CN102027019A - 高密度脂蛋白样肽磷脂支架("hpps")纳米颗粒 - Google Patents
高密度脂蛋白样肽磷脂支架("hpps")纳米颗粒 Download PDFInfo
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- CN102027019A CN102027019A CN200880126584XA CN200880126584A CN102027019A CN 102027019 A CN102027019 A CN 102027019A CN 200880126584X A CN200880126584X A CN 200880126584XA CN 200880126584 A CN200880126584 A CN 200880126584A CN 102027019 A CN102027019 A CN 102027019A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6917—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a lipoprotein vesicle, e.g. HDL or LDL proteins
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
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- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
- A61K49/0082—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion micelle, e.g. phospholipidic micelle and polymeric micelle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
- G01N33/587—Nanoparticles
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
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- Cell Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
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- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610245387.6A CN105903029A (zh) | 2007-12-12 | 2008-12-12 | 高密度脂蛋白样肽磷脂支架(“hpps”)纳米颗粒 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1323307P | 2007-12-12 | 2007-12-12 | |
| US61/013,233 | 2007-12-12 | ||
| US10450608P | 2008-10-10 | 2008-10-10 | |
| US61/104,506 | 2008-10-10 | ||
| PCT/CA2008/002203 WO2009073984A1 (en) | 2007-12-12 | 2008-12-12 | High-density lipoprotein-like peptide-phospholipid scaffold ('hpps') nanoparticles |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610245387.6A Division CN105903029A (zh) | 2007-12-12 | 2008-12-12 | 高密度脂蛋白样肽磷脂支架(“hpps”)纳米颗粒 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102027019A true CN102027019A (zh) | 2011-04-20 |
Family
ID=40755223
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880126584XA Pending CN102027019A (zh) | 2007-12-12 | 2008-12-12 | 高密度脂蛋白样肽磷脂支架("hpps")纳米颗粒 |
| CN201610245387.6A Pending CN105903029A (zh) | 2007-12-12 | 2008-12-12 | 高密度脂蛋白样肽磷脂支架(“hpps”)纳米颗粒 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610245387.6A Pending CN105903029A (zh) | 2007-12-12 | 2008-12-12 | 高密度脂蛋白样肽磷脂支架(“hpps”)纳米颗粒 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110020242A1 (enExample) |
| EP (1) | EP2229411B1 (enExample) |
| JP (1) | JP5658568B2 (enExample) |
| CN (2) | CN102027019A (enExample) |
| CA (1) | CA2708719A1 (enExample) |
| WO (1) | WO2009073984A1 (enExample) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013181934A1 (zh) * | 2012-06-07 | 2013-12-12 | 华中科技大学 | 一种具有协同靶向诊疗鼻咽癌功能的多肽和携带此多肽的纳米颗粒及其应用 |
| CN103910802A (zh) * | 2014-04-24 | 2014-07-09 | 华中科技大学 | 一种促进树突细胞摄取抗原肽的多肽、促进树突细胞摄取抗原肽的纳米颗粒及其应用 |
| CN106659684A (zh) * | 2014-06-20 | 2017-05-10 | 大学健康网络 | 含肽的卟啉脂质纳米囊泡 |
| CN106831997A (zh) * | 2015-12-03 | 2017-06-13 | 中国科学院苏州纳米技术与纳米仿生研究所 | 多肽、脂蛋白样纳米粒子及其应用 |
| CN108143719A (zh) * | 2017-12-27 | 2018-06-12 | 华中科技大学 | 一种携载多肽的纳米脂质体及其制备方法和应用 |
| CN111012555A (zh) * | 2019-12-03 | 2020-04-17 | 刘训伟 | 载放射性核素微纳米涂层支架及其制备方法 |
| CN111494641A (zh) * | 2020-04-22 | 2020-08-07 | 南开大学 | 肿瘤微环境响应性的表面电荷可反转纳米药物递送载体 |
| CN111971028A (zh) * | 2017-11-21 | 2020-11-20 | 西奈山伊坎医学院 | 用治疗性纳米生物组合物促进训练免疫 |
| US11859021B2 (en) | 2021-03-19 | 2024-01-02 | Icahn School Of Medicine At Mount Sinai | Compounds for regulating trained immunity, and their methods of use |
| US12377054B2 (en) | 2016-04-29 | 2025-08-05 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
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| WO2010057203A2 (en) | 2008-11-17 | 2010-05-20 | The Board Of Regents Of The University Of Texas System | Hdl particles for delivery of nucleic acids |
| US20100233270A1 (en) | 2009-01-08 | 2010-09-16 | Northwestern University | Delivery of Oligonucleotide-Functionalized Nanoparticles |
| WO2011035279A2 (en) * | 2009-09-21 | 2011-03-24 | Board Of Regents, The University Of Texas System | Nanocarriers for imaging and therapy applications |
| US10498796B2 (en) * | 2009-10-16 | 2019-12-03 | Real Innovations International Llc | System and method for providing real-time data |
| US20130034599A1 (en) | 2010-01-19 | 2013-02-07 | Northwestern University | Synthetic nanostructures including nucleic acids and/or other entities |
| KR101405403B1 (ko) * | 2010-01-20 | 2014-06-11 | 주식회사 진코스 | 클로린 유도체와 불포화 지방산의 접합체, 이를 함유하는 광감작제, 및 이를 포함하는 광역학 치료에 사용하기 위한 암 치료용 조성물 |
| US9592268B2 (en) | 2011-05-23 | 2017-03-14 | Cornell University | Endothelium protective materials and methods of use |
| CA2883080A1 (en) * | 2011-08-26 | 2013-03-07 | Vecoy Nanomedicines Ltd. | Pathogen and substance traps |
| US9901616B2 (en) | 2011-08-31 | 2018-02-27 | University Of Georgia Research Foundation, Inc. | Apoptosis-targeting nanoparticles |
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| JP2014129317A (ja) * | 2012-02-23 | 2014-07-10 | Canon Inc | 光音響造影剤用色素含有ナノ粒子 |
| EP2882459A1 (en) | 2012-08-10 | 2015-06-17 | University of North Texas Health Science Center | Drug delivery vehicle comprising conjugates between targeting polyamino acids and fatty acids |
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| US9371364B2 (en) | 2012-06-07 | 2016-06-21 | Huazhong University Of Science And Technology | Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof |
| WO2013181934A1 (zh) * | 2012-06-07 | 2013-12-12 | 华中科技大学 | 一种具有协同靶向诊疗鼻咽癌功能的多肽和携带此多肽的纳米颗粒及其应用 |
| CN103910802A (zh) * | 2014-04-24 | 2014-07-09 | 华中科技大学 | 一种促进树突细胞摄取抗原肽的多肽、促进树突细胞摄取抗原肽的纳米颗粒及其应用 |
| CN106659684A (zh) * | 2014-06-20 | 2017-05-10 | 大学健康网络 | 含肽的卟啉脂质纳米囊泡 |
| CN106831997B (zh) * | 2015-12-03 | 2020-04-24 | 中国科学院苏州纳米技术与纳米仿生研究所 | 多肽、脂蛋白样纳米粒子及其应用 |
| CN106831997A (zh) * | 2015-12-03 | 2017-06-13 | 中国科学院苏州纳米技术与纳米仿生研究所 | 多肽、脂蛋白样纳米粒子及其应用 |
| US12377054B2 (en) | 2016-04-29 | 2025-08-05 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| CN111971028A (zh) * | 2017-11-21 | 2020-11-20 | 西奈山伊坎医学院 | 用治疗性纳米生物组合物促进训练免疫 |
| CN108143719A (zh) * | 2017-12-27 | 2018-06-12 | 华中科技大学 | 一种携载多肽的纳米脂质体及其制备方法和应用 |
| CN111012555A (zh) * | 2019-12-03 | 2020-04-17 | 刘训伟 | 载放射性核素微纳米涂层支架及其制备方法 |
| CN111494641A (zh) * | 2020-04-22 | 2020-08-07 | 南开大学 | 肿瘤微环境响应性的表面电荷可反转纳米药物递送载体 |
| CN111494641B (zh) * | 2020-04-22 | 2021-08-03 | 南开大学 | 肿瘤微环境响应性的表面电荷可反转纳米药物递送载体 |
| US11859021B2 (en) | 2021-03-19 | 2024-01-02 | Icahn School Of Medicine At Mount Sinai | Compounds for regulating trained immunity, and their methods of use |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2229411A1 (en) | 2010-09-22 |
| CA2708719A1 (en) | 2009-06-18 |
| CN105903029A (zh) | 2016-08-31 |
| JP5658568B2 (ja) | 2015-01-28 |
| US20110020242A1 (en) | 2011-01-27 |
| JP2011507807A (ja) | 2011-03-10 |
| EP2229411B1 (en) | 2019-02-27 |
| EP2229411A4 (en) | 2015-03-04 |
| WO2009073984A1 (en) | 2009-06-18 |
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