CN102008625B - Medicine for treating tuberculous lymphadenitis and preparation method thereof - Google Patents

Medicine for treating tuberculous lymphadenitis and preparation method thereof Download PDF

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CN102008625B
CN102008625B CN201010558546A CN201010558546A CN102008625B CN 102008625 B CN102008625 B CN 102008625B CN 201010558546 A CN201010558546 A CN 201010558546A CN 201010558546 A CN201010558546 A CN 201010558546A CN 102008625 B CN102008625 B CN 102008625B
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黄书芳
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Abstract

The invention discloses a medicine for treating tuberculous lymphadenitis. The medicine comprises the following components in parts by weight: 5-9 parts of borneol, 500 parts of fresh cinnamomvine, 8-12 parts of Cryptotympana pustulata Fabricius, 3-5 parts of toad, 5-10 parts of golden scorpion, 9-15 parts of apiary, 9-20 parts of forged calamine, 5-10 parts of frankincense, 5-10 parts of myrrh, 10-12 parts of Astragalus membranaceus and 45 parts of Salvia miltiorrhiza bunge, wherein all the components are organically compatible and have synergistic effect, thus the medicine has a unique penetration function, can reach the nidus directly with strong drug effect, can externally cure internal diseases, can be subject to transdermal absorption, and has the efficacies of activating blood, dissolving stasis, warming meridians, regulating the flow of vital energy, removing obstruction, relieving pain, dispersing pathogenic wind and expelling toxin, so that the medicine generates strong drug effect to effectively remove the organism nidus, thereby achieving favorable curative effect.

Description

Scrofulous medicine of a kind of treatment and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine preparation, specifically, relate to a kind of scrofulous medicine and preparation method thereof that is used for the treatment of, belong to the Chinese medicine technical field.
Background technology
Lymphoid tuberculosis is by the lymph node chronic inflammation due to the mycobacterium tuberculosis infection, so be also referred to as tuberculous lymphadenitis, is the more common disease of surgery.The approach that tubercule bacillus is invaded cervical lymph node has four kinds: tulase enters the hilus pulumonis mediastinal lymph nodes in (1) pulmonary lesion, at up arrival cervical lymph node, causes tuberculous lymphadenitis; (2) lymph node has oral cavity, nasopharynx part or tonsil to invade lymph net under the mucosa more, arrives at cervical lymph node by lymphatic vessel.The lymphoid tuberculosis people that this approach causes is mostly occurred on neck top; (3) tulase of apex pulmonis portion reaches cervical lymph node by pleural adhesion with the lymphatic drainage sword, is many with one-sided morbidity; (4) by hematogenous spread generation pathological changes, lymphoid tuberculosis is a topical manifestations of whole body hematogenous spread tuberculosis, bilateral morbidity mostly.
More than the cause and the clinical manifestation of several diseases: morbidity the lighter can not have any General Symptoms, and heavier person can produce whole body tuberculosis and poisoning symptom, sees in that the child is more.Tuberculosis of cervical lymph nodes feels that mostly there is the swelling sense part, pain and local redness etc.In conjunction with plain reaction of inspection palpation knot and clinical experience, can be divided into five types.(1) initial stage swelling type: after finding cervical lymph node swelling, can successively occur 1 to several lymphadenectasis in a couple of days, touch it with pointing, high resilience and does not have adhesion on every side, and is removable, and slight tenderness is arranged, and skin is not rubescent, the ripple disable of touching; (2) invade the profit type: tangible perilymphadenitis is arranged, and adhesion is arranged on every side, mobile restricted, tenderness is more obvious, can form sometimes as the swollen thing of bread.Can contact the big enlarged lymph node of the big goose egg of thumb head; (3) ulcer fistula pass: on the enlarged lymph node surface fistula hole is arranged, often suppurate, the surface can form one deck skin crust sometimes, and through fistula orifice flow pus still can be arranged in short-term, natural healing person seldom; (4) hardening: through the longer stage, enlarged lymph node elasticity disappears after the morbidity, and that touches is harder, can move, not have tenderness, belongs to stable phase this moment, as without regular reasonable antituberculosis therapy, recurrence suppuration possibility can be arranged.
The lymphoid tuberculosis drug resistance is strong, the relapse rate height, and treatment cycle is long, and financial burden is heavy.The routine treatment of doctor trained in Western medicine is an anti-inflammatory and antalgic at present, take antiinflammation pain-stopping pharmaceutical more, can cause renal function to go down and take this class medicine, diseases such as the edema of the face, osteoporosis, limbs fatigue, anorexia, spirit are sleepy, infringement liver function, also have and adopt the excision lymph node, but damage accessory nerve easily, certain danger is arranged; And general Chinese medicine preparation is limited by the efficacy of a drug of digesting and assimilating, reach focus of intestinal as decoction, so patient's obstinate delays time of treatment.
Summary of the invention
The problem that invention will solve is at above deficiency, and scrofulous medicine of a kind of treatment and preparation method thereof is provided, and this medicine is blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, the knot pain relieving that disappears of regulating the flow of vital energy fast.
For solving above technical problem, the technical solution adopted in the present invention is: the scrofulous medicine of a kind of treatment, and it is characterized in that: described medicine comprises the composition of following weight portion:
45 parts of Borneolum Syntheticum 5-9 part, 500 parts of fresh Rhizoma dioscoreae, cicada 8-12 part, Bufo siccus 3-5 part, Scorpio 5-10 part, Nidus Vespae 9-15 part, Calamina (calcined and quenched) 9-20 part, Olibanum 5-10 part, Myrrha 5-10 part, Radix Astragali 10-12 part and Radix Salviae Miltiorrhizaes.
As further improvement in the technical proposal:
Described medicine comprises the composition of following weight portion:
45 parts of Borneolum Syntheticum 6-8 part, 500 parts of fresh Rhizoma dioscoreae, cicada 9-11 part, Bufo siccus 3-5 part, Scorpio 6-8 part, Nidus Vespae 9-13 part, Calamina (calcined and quenched) 10-15 part, Olibanum 6-8 part, Myrrha 6-9 part, Radix Astragali 11-12 part and Radix Salviae Miltiorrhizaes.
Described medicine comprises the composition of following weight portion:
45 parts of 7 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 10 parts of cicada, 4 parts of Bufo siccuss, 6 parts of Scorpios, 9 parts in Nidus Vespae, 12 parts of Calamina (calcined and quenched), 7 parts of Olibanums, 6 parts of Myrrhas, 12 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
A kind of preparation method for the treatment of scrofulous medicine may further comprise the steps preparation:
A, get each composition according to described weight portion, Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae are pulverized, bottling respectively is standby then;
B, fresh Rhizoma dioscoreae is ground into Rhizoma dioscoreae paste, with pulverize after Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae furnishing pasty state, scrofulous medicine obtains medical treatment.
In the above composition,
Borneolum Syntheticum, sensible heat radiation, anti-inflammatory analgetic are used for that calentura is refreshing dizzy, heatstroke, external treatment throat, gingival swelling and pain, aphtha of the mouth and tongue, conjunctival congestion, pain be swollen.
Rhizoma Dioscoreae, supplementing QI and nourishing YIN, invigorating the spleen to benefit the lung, the kidney invigorating arresting seminal emission.
Cicada, loose wind heat, lung qi dispersing, rash, spasmolytic are applicable to affection due to external wind and heat, laryngopharynx swelling and pain, infantile convulsion and tetanic tic.
Bufo siccus, detoxifcation diuretic, parasite killing analgesic therapy can be controlled the malignant boil tumor, can ward off dirty epidemic disease poison, and be effective to pestilence.
Nidus Vespae, the wind dispelling insecticide detoxifcation is used for skin stubborn dermatitis, skin infection detoxifcation, lymphoid tuberculosis, diseases such as headache.
Scorpio, wind-expelling pain-stopping is usually used in convulsion with spasms, apoplexy, hemiplegia, rheumatic arthralgia, and detoxifcation heat radiation again is applicable to the swollen grade of lymphoid tuberculosis rubella skin ulcer disease.
Calamina (calcined and quenched) detoxifies, makes eye bright, the antipruritic skin ulcer of holding back, and is applicable to conjunctival congestion, diseases such as the wound ulcer that swells and ache is not held back, skin eczema.
Olibanum, blood-activating and qi-promoting, pain relieving, detumescence and promoting granulation.
Myrrha, loose blood detumescence, analgesic therapy, granulation promoting are applicable to that traumatic pain, rheumatic arthralgia blood stasis gather diseases such as in bulk.
The Radix Astragali, spleen reinforcing are good for the stomach, invigorating the lung and benefiting vital QI, strengthening superficial resistance to stop perspiration, evacuation of pus granulation promoting, are applicable to the spontaneous perspiration due to the deficiency of vital energy, suffer from diseases such as skin infection for a long time.
Radix Salviae Miltiorrhizae, the blood stasis of living, tissue regeneration promoting blood, removing heat from blood, knot gather.Abdominal pain due to blood stasis, malignant boil swells and ache.
The present invention adopts above technical scheme, compared with prior art, have the following advantages: cicada among the present invention, Bufo siccus, Scorpio, Nidus Vespae and Calamina (calcined and quenched) are principal agent, Olibanum, Myrrha and Radix Salviae Miltiorrhizae are accessory drugs, Borneolum Syntheticum is for making, fresh Rhizoma dioscoreae, the Radix Astragali is assistant, Olibanum, Myrrha, Borneolum Syntheticum and Radix Salviae Miltiorrhizae cooperate, Borneolum Syntheticum has strengthened Olibanum, the osmosis of Myrrha and Radix Salviae Miltiorrhizae, bring into play the blood circulation promoting and blood stasis dispelling of principal agent effectively, promoting the flow of QI in the collateral by warming the meridian, the knot analgesic effect that disappears of regulating the flow of vital energy, fresh Rhizoma dioscoreae, Radix Astragali human body immunity improving power, the therapeutic effect of enhancing principal agent, the organic compatibility of each component, synergism has unique infiltration function, with the through focus of powerful drug effect, inner disease outer treat, Transdermal absorption reaches blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian, the knot pain relieving that disappears of regulating the flow of vital energy, the toxin expelling that dispels the wind makes this medicine produce powerful drug effect, effectively get rid of the body focus, reach excellent curative.
The invention will be further described below in conjunction with embodiment.
The specific embodiment
Embodiment 1, the scrofulous medicine of a kind of treatment comprises the composition of following weight portion: 45 parts of 5 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 8 parts of cicada, 3 parts of Bufo siccuss, 10 parts of Scorpios, 15 parts in Nidus Vespae, 20 parts of Calamina (calcined and quenched), 5 parts of Olibanums, 10 parts of Myrrhas, 10 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
Embodiment 2, the scrofulous medicine of a kind of treatment comprises the composition of following weight portion: 45 parts of 6 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 9 parts of cicada, 5 parts of Bufo siccuss, 5 parts of Scorpios, 10 parts in Nidus Vespae, 10 parts of Calamina (calcined and quenched), 6 parts of Olibanums, 5 parts of Myrrhas, 11 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
Embodiment 3, the scrofulous medicine of a kind of treatment comprises the composition of following weight portion: 45 parts of 7 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 10 parts of cicada, 4 parts of Bufo siccuss, 6 parts of Scorpios, 9 parts in Nidus Vespae, 12 parts of Calamina (calcined and quenched), 7 parts of Olibanums, 6 parts of Myrrhas, 12 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
Embodiment 4, the scrofulous medicine of a kind of treatment comprises the composition of following weight portion: 45 parts of 8 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 11 parts of cicada, 3 parts of Bufo siccuss, 7 parts of Scorpios, 11 parts in Nidus Vespae, 9 parts of Calamina (calcined and quenched), 8 parts of Olibanums, 9 parts of Myrrhas, 10 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
Embodiment 5, the scrofulous medicine of a kind of treatment comprises the composition of following weight portion: 45 parts of 6 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 12 parts of cicada, 4 parts of Bufo siccuss, 8 parts of Scorpios, 13 parts in Nidus Vespae, 15 parts of Calamina (calcined and quenched), 10 parts of Olibanums, 7 parts of Myrrhas, 11 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
The scrofulous medicine of treatment prepares according to following steps respectively among the above embodiment:
A, get each composition according to described weight portion, Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae are pulverized, bottling respectively is standby then;
B, again fresh Rhizoma dioscoreae is ground into Rhizoma dioscoreae paste, with pulverize after Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae furnishing pasty state, scrofulous medicine obtains medical treatment.
Above embodiment prepares the using method of medicine: treat scrofulous medicine fully in order to the top legal system, apply in half an hour at affected area, twice, 15 day on the one is a course of treatment.
Above five embodiment gained medicines are used for the treatment of scrofulous test, this test is from year August in March, 2009 to 2010,250 patients are treated, be provided with 5 test group, each test group is treated 50 patients respectively, the medicine of test group 1 usefulness embodiment 1 gained, the medicine of test group 2 usefulness embodiment 2 gained, the medicine of test group 3 usefulness embodiment 3 gained, the medicine of test group 4 usefulness embodiment 4 gained, the medicine of test group 5 usefulness embodiment 5 gained.
The use efficacy assessment standard is: produce effects: transference cure; Effectively: doing well,improving; Invalid: doing well,improving is not obvious.
Result such as following table that test obtains:
Figure GSB00000594085500041
Figure GSB00000594085500051
Find out from above data, gained treatment tuberculous lymphadenitis of the present invention, total effective rate reaches more than 70%, and in above embodiment, embodiment 3 is a preferred plan.

Claims (4)

1. treat scrofulous medicine for one kind, it is characterized in that: described medicine is grouped into by the one-tenth of following weight portion:
45 parts of Borneolum Syntheticum 5-9 part, 500 parts of fresh Rhizoma dioscoreae, cicada 8-12 part, Bufo siccus 3-5 part, Scorpio 5-10 part, Nidus Vespae 9-15 part, Calamina (calcined and quenched) 9-20 part, Olibanum 5-10 part, Myrrha 5-10 part, Radix Astragali 10-12 part and Radix Salviae Miltiorrhizaes.
2. the scrofulous medicine of a kind of treatment as claimed in claim 1, it is characterized in that: described medicine is grouped into by the one-tenth of following weight portion:
45 parts of Borneolum Syntheticum 6-8 part, 500 parts of fresh Rhizoma dioscoreae, cicada 9-11 part, Bufo siccus 3-5 part, Scorpio 6-8 part, Nidus Vespae 9-13 part, Calamina (calcined and quenched) 10-15 part, Olibanum 6-8 part, Myrrha 6-9 part, Radix Astragali 11-12 part and Radix Salviae Miltiorrhizaes.
3. the scrofulous medicine of a kind of treatment as claimed in claim 1, it is characterized in that: described medicine is grouped into by the one-tenth of following weight portion:
45 parts of 7 parts of Borneolum Syntheticums, 500 parts of fresh Rhizoma dioscoreae, 10 parts of cicada, 4 parts of Bufo siccuss, 6 parts of Scorpios, 9 parts in Nidus Vespae, 12 parts of Calamina (calcined and quenched), 7 parts of Olibanums, 6 parts of Myrrhas, 12 parts of the Radixs Astragali and Radix Salviae Miltiorrhizaes.
4. as one of them described a kind of preparation method for the treatment of the tuberculous lymphadenitis medicine of claim 1-3, it is characterized in that:
Get each composition according to described weight portion, Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae are pulverized, bottling respectively is standby then;
Fresh Rhizoma dioscoreae is ground into Rhizoma dioscoreae paste, and with Borneolum Syntheticum, cicada, Bufo siccus, Scorpio, Nidus Vespae, Calamina (calcined and quenched), Olibanum, Myrrha, the Radix Astragali and Radix Salviae Miltiorrhizae furnishing pasty state after the pulverizing, scrofulous medicine obtains medical treatment.
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CN1883596A (en) * 2006-05-18 2006-12-27 王培业 Chinese medicinal composition for treating lymphnode tuberculosis

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CN1273848A (en) * 1999-05-14 2000-11-22 王志明 Chinese medicine for treating tuberculosis
CN1748737A (en) * 2005-10-20 2006-03-22 北京阜康仁生物制药科技有限公司 Xiaojin preparation and new preparing method

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CN1883596A (en) * 2006-05-18 2006-12-27 王培业 Chinese medicinal composition for treating lymphnode tuberculosis

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