Summary of the invention
Goal of the invention: the object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of pain, the present invention also provides the preparation method of said preparation, to realizing that the alleviating pain effect is strong, onset time is fast, long action time.
Technical scheme: in order to realize the foregoing invention purpose, the technical solution adopted in the present invention is:
A kind of Chinese medicine preparation that is used for the treatment of pain, be comprised of the raw material of following parts by weight: 10~20 parts, Moschus, 10~20 parts of Radix Saposhnikoviaes, 10~20 parts of the Radixs Angelicae Dahuricae, 10~20 parts of Herba Asaris, 10~40 parts of Caulis Sinomeniis, 10~40 parts of Rhizoma Et Radix Notopterygiis, 10~30 parts of Radix Angelicae Pubescentiss, 10~30 parts of Olibanums, 10~30 parts of Myrrhas, 15~25 parts of Radix Aconiti Preparatas, 15~25 parts of Radix Salviae Miltiorrhizaes, 15~30 parts of Herba Epimedii, 15~25 parts of Herba Lycopodiis, 15~30 parts of Herba speranskiae tuberculataes.
Preferably, the raw material by following parts by weight forms: 10~15 parts, Moschus, 10~15 parts of Radix Saposhnikoviaes, 10~15 parts of the Radixs Angelicae Dahuricae, 10~15 parts of Herba Asaris, 20~30 parts of Caulis Sinomeniis, 10~30 parts of Rhizoma Et Radix Notopterygiis, 10~20 parts of Radix Angelicae Pubescentiss, 10~20 parts of Olibanums, 20~30 parts of Myrrhas, 15~20 parts of Radix Aconiti Preparatas, 15~20 parts of Radix Salviae Miltiorrhizaes, 15~25 parts of Herba Epimedii, 15~20 parts of Herba Lycopodiis, 20~30 parts of Herba speranskiae tuberculataes.
Preferably, the raw material by following parts by weight forms: 20 parts, Moschus, 15 parts of Radix Saposhnikoviaes, 15 parts of the Radixs Angelicae Dahuricae, 15 parts of Herba Asaris, 20 parts of Caulis Sinomeniis, 30 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Radix Angelicae Pubescentiss, 20 parts of Olibanums, 20 parts of Myrrhas, 15 parts of Radix Aconiti Preparatas, 15 parts of Radix Salviae Miltiorrhizaes, 15 parts of Herba Epimedii, 20 parts of Herba Lycopodiis, 20 parts of Herba speranskiae tuberculataes.
Method for the preparation of the Chinese medicine preparation for the treatment of pain, the step of described method is: Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae are pressed to quality proportioning prescription, ethanol 2000~5000ml by volumetric concentration 75%, after soaking 15d, filter, the prepared slices of Chinese crude drugs that will soak again are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to the ethanol volumetric concentration 30~40%; The medicinal liquid dress spray bottle configured is standby.
Beneficial effect: compared with prior art, remarkable advantage of the present invention is: raw material sources of the present invention are extensive, cheap; Chinese medicine preparation of the present invention is evident in efficacy on treating on pain, and total treated effect is 96%; On alleviating pain, effect is remarkable, significantly reduces pain; Pain relieving time is short, rapid-action; Preparation method of the present invention is simple, and the preparation of making is easy to use.
The specific embodiment
Below by specific embodiment, the present invention is further described; it should be pointed out that for the person of ordinary skill of the art, under the premise without departing from the principles of the invention; can also make some modification and improvement, these also should be considered as belonging to protection scope of the present invention.
Embodiment 1
Get Moschus 10g, Radix Saposhnikoviae 10g, Radix Angelicae Dahuricae 10g, Herba Asari 10g, Caulis Sinomenii 10g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Pubescentis 10g, Olibanum 10g, Myrrha 10g, Radix Aconiti Preparata 15g, Radix Salviae Miltiorrhizae 15g, Herba Epimedii 15g, Herba Lycopodii 15g, Herba speranskiae tuberculatae 15g.Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae are pressed to quality proportioning prescription, ethanol 2000ml by volumetric concentration 75%, after soaking 15d, filter, the prepared slices of Chinese crude drugs that will soak again are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to the ethanol volumetric concentration 30%; The medicinal liquid dress spray bottle configured is standby.
Embodiment 2
Get Moschus 20g, Radix Saposhnikoviae 20g, Radix Angelicae Dahuricae 20g, Herba Asari 20g, Caulis Sinomenii 40g, Rhizoma Et Radix Notopterygii 40g, Radix Angelicae Pubescentis 30g, Olibanum 30g, Myrrha 30g, Radix Aconiti Preparata 25g, Radix Salviae Miltiorrhizae 25g, Herba Epimedii 30g, Herba Lycopodii 25g, Herba speranskiae tuberculatae 30g.Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae are pressed to quality proportioning prescription, ethanol 5000ml by volumetric concentration 75%, after soaking 15d, filter, the prepared slices of Chinese crude drugs that will soak again are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to the ethanol volumetric concentration 40%; The medicinal liquid dress spray bottle configured is standby.
Embodiment 3
Get Moschus 15g, Radix Saposhnikoviae 15g, Radix Angelicae Dahuricae 15g, Herba Asari 15g, Caulis Sinomenii 30g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Pubescentis 20g, Olibanum 20g, Myrrha 20g, Radix Aconiti Preparata 20g, Radix Salviae Miltiorrhizae 20g, Herba Epimedii 20g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 25g.Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae are pressed to quality proportioning prescription, ethanol 3000ml by volumetric concentration 75%, after soaking 15d, filter, the prepared slices of Chinese crude drugs that will soak again are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to the ethanol volumetric concentration 35%; The medicinal liquid dress spray bottle configured is standby.
Embodiment 4
Get Moschus 20g, Radix Saposhnikoviae 15g, Radix Angelicae Dahuricae 15g, Herba Asari 15g, Caulis Sinomenii 20g, Rhizoma Et Radix Notopterygii 30g, Radix Angelicae Pubescentis 15g, Olibanum 20g, Myrrha 20g, Radix Aconiti Preparata 15g, Radix Salviae Miltiorrhizae 15g, Herba Epimedii 15g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g.Radix Saposhnikoviae, the Radix Angelicae Dahuricae, Herba Asari, Caulis Sinomenii, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Olibanum, Myrrha, Radix Aconiti Preparata, Radix Salviae Miltiorrhizae, Herba Epimedii, Herba Lycopodii, Herba speranskiae tuberculatae are pressed to quality proportioning prescription, ethanol 4000ml by volumetric concentration 75%, after soaking 15d, filter, the prepared slices of Chinese crude drugs that will soak again are placed in boiling machine and decoct with water, filtering liquid medicine and alcoholic extract mix, extract supernatant after precipitation, add Moschus, be adjusted to the ethanol volumetric concentration 40%; The medicinal liquid dress spray bottle configured is standby.
Embodiment 5
100 scapulohumeral periarthritis pain patients of random selection are carried out clinical observation.Be divided into matched group and treatment group, every group of each 50 people.Two groups of ages, sex, course of disease comparable situation are in Table 1.
Table 1
? |
Age/year |
Men and women's ratio |
The course of disease/year |
Matched group |
52.5±6.3 |
0.43 |
5.1±0.6 |
Treatment group |
53.1±5.8 |
0.47 |
4.8±1.1 |
1, experimental technique
Treatment group application Chinese medicine percutaneous drug treatment, be specially: the medicinal liquid that embodiment 1 is prepared directly is sprayed on diseased region, every day 4 times or several; The control group ibuprofen, each 2, every day 3 times, oral, local with damp-affection and pain relieving patch affected part, coordinate physical therapy.
2, observation index
1) treatment fore-and-aft observing patient pain relieving time: from the patient, receive treatment and start the time changed to pain relief, scoring.
2) pain relief situation: pain degree is judged with reference to the pain scores method.1. 0 minute: without any pain; 2. slight (1 minute): indistinctly can feel and mild pain not cause worry; 3. moderate (2 minutes): often feel pain, but do not affect daily routines, can tolerate; 4. severe (3 minutes): often feel obvious pain, and affect daily routines and sleep, or be impatient at.
3, curative effect determinate standard
Cure: through treating various pain symptoms, disappear, function recovers normal fully or substantially, and pain scores is 0 minute;
Take a turn for the better: symptom disappears substantially, and shoulder joint function improves, more than the pain scores reduction reaches in 1 minute;
Invalid: more than treatment 15d, symptom and pain still do not alleviate, and function is not improved.
4, experimental result
4.1 therapeutic effect
Therapeutic outcome is in Table 2.Visible, the total effective rate for the treatment of group is far away higher than matched group, evident in efficacy.
Table 2 therapeutic effect relatively
? |
Healing/example |
Improvement/example |
Invalid/example |
Total effective rate/% |
Matched group |
15 |
20 |
15 |
70 |
Treatment group |
26 |
22 |
2 |
96 |
4.2 pain scores relatively
The pain scores comparative result is in Table 3, and visible treatment group scoring is significantly lower than matched group, and on alleviating pain, effect is remarkable.
Before and after table 3 treatment, two groups of pain scores relatively
? |
Before treatment |
After treatment |
Matched group |
2.3±0.6 |
1.4±0.7 |
Treatment group |
2.3±0.9 |
0.8±0.2 |
4.3 pain relieving time
The matched group pain relieving time is 15.7 ± 3.8h, and the treatment group pain relieving time is 4.2 ± 1.2h, and the treatment group pain relieving time, significantly lower than matched group, illustrates rapid-action.