CN102389549B

CN102389549B - Traditional Chinese medicinal composition for treating psoriasis

Info

Publication number: CN102389549B
Application number: CN201110384020.XA
Authority: CN
Inventors: 王娟
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-11-28
Filing date: 2011-11-28
Publication date: 2014-07-30
Anticipated expiration: 2031-11-28
Also published as: CN102389549A

Abstract

Belonging to the traditional Chinese medicine field, the invention especially discloses a traditional Chinese medicinal composition for treating psoriasis. The traditional Chinese medicine takes moutan bark, dry radix rehmanniae, rhizoma imperatae, raw rhizoma atractylodis macrocephalae, plantain seeds, cortex dictamni, zaocys dhumnades, gentiana macrophylla, coptis chinensis, rheum officinale, radix rhapontici, Chinese Angelica, smilax glabra, agaric, fructus kochiae, and nidus vespae as active components, and is composed in certain weight ratio. The traditional Chinese medicine of the invention is special for treating psoriasis and is coordinated by a plurality of medicines. The synergistic or resisting effects among the medicines can improve the curative effect so as to adapt to treatment requirements of complex disease conditions and reduce adverse reactions. The traditional Chinese medicinal composition provided in the invention has the advantages of simple formula, substantial curative effect, safety and reliability, simple administration, good treatment effect on psoriasis, and pain relieving as well as economic burden alleviating for patients simultaneously. Applied in treatment of 152 cases totally, the traditional Chinese medicinal composition of the invention has a total effective rate up to 99%.

Description

One is treated psoriatic oral traditional Chinese medicine composition

(1) technical field

The invention belongs to the field of Chinese medicines, particularly one is treated psoriatic oral traditional Chinese medicine composition.

(2) background technology

Psoriasis is a kind of common chronic recurrent inflammatory skin disease, is commonly called as " psoriasis ", is also " chronic eczema ", " tinea alba ", " tinea corporis " etc. in the traditional Chinese medical science.The cause of disease is still not exclusively clear and definite at present, is still a world medicine difficult problem.For a long time, on clinical treatment, because its morbidity is chronic, doctor trained in Western medicine is difficult to treatment, and patient does not feel like oneself for a long time, has had a strong impact on patient's daily life, and psoriasis shows effect repeatedly, usually needs repeatedly to treat, and has also brought very large financial burden to patient.

(3) summary of the invention

The present invention, in order to make up the deficiencies in the prior art, provides a kind of psoriatic oral traditional Chinese medicine composition for the treatment of simple, evident in efficacy of filling a prescription.

The present invention is achieved through the following technical solutions:

One is treated psoriatic oral traditional Chinese medicine composition, and its special character is: its active component is made up of the raw material of following parts by weight:

Cortex Moutan 10-15 part, Radix Rehmanniae 15-20 part, Rhizoma Imperatae 15-20 part

Rhizoma Atractylodis Macrocephalae 10-12 part, Semen Plantaginis 10-12 part, Cortex Dictamni 15-25 part

Zaocys 6-9 part, Radix Gentianae Macrophyllae 10-12 part, Rhizoma Coptidis 6-9 part

Radix Et Rhizoma Rhei 9-15 part, Radix Rhapontici 6-9 part, Radix Angelicae Sinensis 10-15 part

Rhizoma Smilacis Glabrae 15-20 part, Polyporus 15-25 part, Fructus Kochiae 15-20 part

Nidus Vespae 20-30 part.

The weight proportion of its preferred each active component is:

12 parts of Cortex Moutans, 17 parts of Radix Rehmanniaes, 18 parts of Rhizoma Imperataes

11 parts of Rhizoma Atractylodis Macrocephalae, 11 parts of Semen Plantaginiss, 20 parts of Cortex Dictamni

7 parts of Zaocyss, 11 parts of Radix Gentianae Macrophyllae, 8 parts of Rhizoma Coptidis

12 parts of Radix Et Rhizoma Rhei, 7 parts of Radix Rhapontici, 12 parts of Radix Angelicae Sinensis

17 parts of Rhizoma Smilacis Glabraes, 20 parts of Polyporus, 18 parts of the Fructus Kochiae

25 parts of Nidus Vespaes.

Usage and dosage: decoct twice with decocting method, twice liquid of boiling medicine is merged, be equally divided into two parts, every day, potion, divided morning, evening to take for twice.

In formula, all medicines share, and have clearing away heat and cooling blood, invigorating blood and dispelling wind, effect of the lung moistening of nourishing blood, invigorating spleen to remove dampness removing toxic substances, are used for the treatment of acute and chronic psoriasis.

Chinese medicine of the present invention is specifically designed to treatment psoriasis, multi-medicament is suitably coordinated, utilize its mutual collaborative or resistant function, improve curative effect, to adapt to the treatment requirement of the complicated state of an illness, reduce untoward reaction, formula is simple, evident in efficacy, safe and reliable, take simply, psoriasis had to good therapeutic effect, in alleviating patient's slight illness again for patient has alleviated financial burden.Treat altogether 152 examples, total effective rate reaches 99%.

(4) detailed description of the invention

Embodiment 1:

Get 12 grams of Cortex Moutans, 17 grams of Radix Rehmanniaes, 18 grams of Rhizoma Imperataes, 11 grams of Rhizoma Atractylodis Macrocephalae, 11 grams of Semen Plantaginiss, 20 grams of Cortex Dictamni, 7 grams of Zaocyss, 11 grams of Radix Gentianae Macrophyllae, 8 grams of Rhizoma Coptidis, 12 grams of Radix Et Rhizoma Rhei, 7 grams of Radix Rhapontici, 12 grams of Radix Angelicae Sinensis, 17 grams of Rhizoma Smilacis Glabraes, 20 grams of Polyporus, 18 grams of the Fructus Kochiae, 25 grams of Nidus Vespaes, above-mentioned raw materials is decocted twice with decocting method, twice liquid of boiling medicine is merged, be equally divided into two parts, every day, potion, divided morning, evening to take for twice.

Embodiment 2:

Get 10 grams of Cortex Moutans, 15 grams of Radix Rehmanniaes, 15 grams of Rhizoma Imperataes, 10 grams of Rhizoma Atractylodis Macrocephalae, 10 grams of Semen Plantaginiss, 15 grams of Cortex Dictamni, 6 grams of Zaocyss, 10 grams of Radix Gentianae Macrophyllae, 6 grams of Rhizoma Coptidis, 9 grams of Radix Et Rhizoma Rhei, 6 grams of Radix Rhapontici, 10 grams of Radix Angelicae Sinensis, 15 grams of Rhizoma Smilacis Glabraes, 15 grams of Polyporus, 15 grams of the Fructus Kochiae, 20 grams of Nidus Vespaes, above-mentioned raw materials is decocted twice with decocting method, twice liquid of boiling medicine is merged, be equally divided into two parts, every day, potion, divided morning, evening to take for twice.

Embodiment 3:

Get 15 grams of Cortex Moutans, 20 grams of Radix Rehmanniaes, 20 grams of Rhizoma Imperataes, 12 grams of Rhizoma Atractylodis Macrocephalae, 12 grams of Semen Plantaginiss, 25 grams of Cortex Dictamni, 9 grams of Zaocyss, 12 grams of Radix Gentianae Macrophyllae, 9 grams of Rhizoma Coptidis, 15 grams of Radix Et Rhizoma Rhei, 9 grams of Radix Rhapontici, 15 grams of Radix Angelicae Sinensis, 20 grams of Rhizoma Smilacis Glabraes, 25 grams of Polyporus, 20 grams of the Fructus Kochiae, 30 grams of Nidus Vespaes, above-mentioned raw materials is decocted twice with decocting method, twice liquid of boiling medicine is merged, be equally divided into two parts, every day, potion, divided morning, evening to take for twice.

Embodiment 4: clinical observation:

(1) clinical data

The inventor in calendar year 2001 so far, 152 routine psoriatics are carried out to clinical observation treatment, wherein, male patient's 118 examples, female patient 34 examples, age reckling 12 years old, the maximum 66 years old.Person's 118 examples between 20-50 year, account for 77.6%; More than 50 years old person's 23 examples, 20 years old following person's 11 example, 30 people of the course of disease more than 1 year, 1 year above, 5 years following person 30 people, more than 10 years person 30 people, the shortest person of the course of disease more than 10 days, elder more than 30 year.

(2) Therapeutic Method

Every day, potion, divided morning, evening to take for twice.Calculate treatment time according to conditions of patients weight, patients with mild was taken about 10 days, and severe case serve on 90 days and can fully recover.

(3) curative effect determinate standard

" healing ": clinical symptoms sign disappears, recovers normal.

" effective ": basic or most of disappearance of clinical symptoms sign.

" effectively ": clinical symptoms is clearly better.

Engineering noise: clinical symptoms sign is without improvement.

(4) therapeutic effect:

Clinical cure 93 examples, account for 61%; Effective 47 examples, account for 31%; Effective 11 examples, account for 7%; Invalid 1 example, total effective rate 99%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, safe, is conducive to patient and alleviates in time condition of illness.

Model case:

Case 1: Zhang, female, 37 years old, Luohe City Lin Ying county, Henan Du Qu people from town.First visit on March 5 in 2005, readme, since 18 years old, first has two ancons to occur little skin lesion, and development gradually, merges in flakes gradually mutually, is examined as psoriasis in locality, and once repeatedly treatment was not healed.After the improper medication in other places, erythra was developed to whole body suddenly afterwards, especially attach most importance to head, lower limb, scalp, trunk, the extremity skin lesion in blocks that all heals is shown in inspection, the scarlet infiltration of substrate, there is silvery white multilamellar squama on surface, after peeling off squama, there is petechia bottom surface, and fingernail has slight thimble pitting.Inspection: hematuria is conventional no abnormality seen just, liver function, kidney merit are normal.Take the embodiment of the present invention 1 decoction of decocting after 10 days, skin lesion is thin out, infiltrates attenuation and soft, take again after 10 days, and the obvious thin out attenuation of skin lesion, surperficial squama disappears substantially, then takes after 15 days, and skin lesion place only leaves over the patch of brown, and surperficial squama all disappears.Treatment is evaluated: cure, on May 10th, 2007 follows up a case by regular visits to, not recurrence, and on May 12nd, 2011 follows up a case by regular visits to, not recurrence.

Case 2: Fang, female, 28 years old, Fang Liu village, Lai He town, Dan County, Shandong, first visit on March 5 in 2008, before 2 years, there is minority macule in portion overhead, upper cover silvery white squama, institute of Zeng Dao county is medical, examined as psoriasis, once arrived Duo Jia hospital and private clinic medical, use multi-medicament not cure, specifically because of flu, trunk, there is same large area erythra in extremity, be fused into again sheet, especially attach most importance to two lower limb, whole body self-induction fever, itch very, and constantly there is new erythra to occur, check: the full crown covers silvery white squama, sheet comes off, trunk, extremity all have squama large as Ulmus pumila L., little of the erythra of syringe needle, after scratching, squama is many, after peeling off, there is petechia.

Inspection: hematuria stool routine examination is normal, liver function, kidney merit are normal.Take the embodiment of the present invention 2 decoction of decocting after 14 days, stable disease, has no new rash and occurs, the attenuation of former erythra squama is thin out, minimizing, substrate is kermesinus, itches and alleviates, no longer sense fever, take again after 10 days, disappear substantially in the large stretch of skin lesion of whole body center, squama disappears, and continues to take 10 days, whole body skin lesion disappears, and cures.Follow up a case by regular visits to not recurrence on May 16th, 2009, on April 7th, 2011 follows up a case by regular visits to, not recurrence.

Case 3: Zhao, man, 25 years old, north pass village, Dan County, Shandong, first visit in March, 2010, found before 3 years that red point-like erythra appears in lower limb, played white squama, once arrived many hospital admissions, was examined as psoriasis, once in other places, oral medicine for external use did not take effect.At present general head of erythra, trunk, extremity, desquamation, pruritus are obvious.Check: erythra is point-like, and color flushing is clouded in head, extremity and trunk, and there is the squama that silvery white is thicker on surface, base coat colour flushing, infiltration.

Inspection: hematuria stool routine examination is normal, liver function, kidney merit are normal.Take the embodiment of the present invention 3 decoction of decocting after 7 days, skin lesion attenuation, color is thin out red by flushing, have no newborn erythra, itch and alleviate, then continue to take after 10 days, head, trunk erythra major part disappear, and present depigmentation, and extremity erythra squama is thin out, thin, but still color red, itch, take again after 7 days, skin rash disappears, present depigmentation, only before lower limb shank, erythra is not moved back only, continues to take 2 weeks, erythra all disappears, clinical cure.On June 10th, 2011 follows up a case by regular visits to, not recurrence.

Claims

1. the psoriatic oral traditional Chinese medicine composition for the treatment of, is characterized by: its active component is made up of the raw material of following parts by weight:

Cortex Moutan 10-15 part, Radix Rehmanniae 15-20 part, Rhizoma Imperatae 15-20 part,

Rhizoma Atractylodis Macrocephalae 10-12 part, Semen Plantaginis 10-12 part, Cortex Dictamni 15-25 part,

Zaocys 6-9 part, Radix Gentianae Macrophyllae 10-12 part, Rhizoma Coptidis 6-9 part,

Radix Et Rhizoma Rhei 9-15 part, Radix Rhapontici 6-9 part, Radix Angelicae Sinensis 10-15 part,

Rhizoma Smilacis Glabrae 15-20 part, Polyporus 15-25 part, Fructus Kochiae 15-20 part,

Nidus Vespae 20-30 part;

Preparation method is decocting method.

2. the psoriatic oral traditional Chinese medicine composition for the treatment of according to claim 1, is characterized by: its active component is made up of the raw material of following parts by weight:

12 parts of Cortex Moutans, 17 parts of Radix Rehmanniaes, 18 parts of Rhizoma Imperataes,

11 parts of Rhizoma Atractylodis Macrocephalae, 11 parts of Semen Plantaginiss, 20 parts of Cortex Dictamni,

7 parts of Zaocyss, 11 parts of Radix Gentianae Macrophyllae, 8 parts of Rhizoma Coptidis,

12 parts of Radix Et Rhizoma Rhei, 7 parts of Radix Rhapontici, 12 parts of Radix Angelicae Sinensis,

17 parts of Rhizoma Smilacis Glabraes, 20 parts of Polyporus, 18 parts of the Fructus Kochiae,

25 parts of Nidus Vespaes;

Preparation method is decocting method.