CN102000004A - Inflammation diminishing and pain relieving lipstick containing zingiber corallinum hance essential oil - Google Patents
Inflammation diminishing and pain relieving lipstick containing zingiber corallinum hance essential oil Download PDFInfo
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- CN102000004A CN102000004A CN 201010561053 CN201010561053A CN102000004A CN 102000004 A CN102000004 A CN 102000004A CN 201010561053 CN201010561053 CN 201010561053 CN 201010561053 A CN201010561053 A CN 201010561053A CN 102000004 A CN102000004 A CN 102000004A
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Abstract
The invention provides a broad spectrum antibiotic, inflammation-diminishing swelling-relieving and pain-relieving functional lipstick, which is suitable for preventing and treating, has short treatment course, low cost, and simple and feasible preparation method. The product comprises the following components in parts by weight: 0.5-3 parts of zingiber corallinum hance essential oil, 10-15 parts of tea tree oil, 10-15 parts of castor oil, 10-15 parts of beewax, 8-10 parts of paraffin oil, 20-40 parts of essential oil, 10-20 parts of triglyceride isooctyl acid ester and 2-6 parts of wool grease, and is prepared by the following steps: heating, congruent melting and evenly stirring the tea tree oil, the castor oil, beewax, the paraffin oil, the wool grease and the triglyceride isooctyl acid ester, and cooling to the temperature of 35-45 DEG C; and adding the zingiber corallinum hance essential oil, fully and evenly stirring and cooling to obtain the product. The functional lipstick has obvious inflammation diminishing, swelling relieving and pain relieving effects, improves the microcirculation obstacle resulted from lip inflammation, promotes the blood circulation, strengthens the self renewal and self repairing of tissues, has rapid effect, short treatment course, high recovery rate and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of lip pomade, particularly a kind of lip pomade that contains natural Zingiber corallinum Hance essential oil with anti-inflammatory analgesic function.
Background technology
Lip is the window of health.Because wind, cold, summer-heat, wet, dry, fiery endogenous cause of ill, external force stimulate the threshold value of resisting that surpasses human body, often cause dry lip, chapped lip, lip boil, lip wound, treat untimely or malpractice, influence the human body physical and mental health, quality of life.Commercially available lip pomade is of all shapes and colors, but mostly is the beauty treatment type, and analgesia, inflammation-diminishing function type lip pomade is few, and effect is undesirable.
Summary of the invention
The purpose of this invention is to provide a kind of lip pomade that contains natural Zingiber corallinum Hance essential oil with anti-inflammatory analgesic function.
The present invention is prepared as follows:
(1) takes by weighing various raw materials by following parts by weight: 0.5～3 part of Rhizoma Zingiberis corallini quintessence oil, 10～15 parts of tea tree oil, 10～15 parts of Oleum Ricini, 10～15 parts in Cera Flava, 8～10 parts of paraffin oil, 20～40 parts in essential oil, 10～20 parts of glycerol three tricaprylates, 2～6 parts of lanolines;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, be cooled to 35～45 ℃, add Rhizoma Zingiberis corallini quintessence oil and stir, cooling gets final product.
The better scope of various raw materials in part by weight is: 1～2 part of Rhizoma Zingiberis corallini quintessence oil, 12～14 parts of tea tree oil, 12～14 parts of Oleum Ricini, 12～14 parts in Cera Flava, 8.5～9.5 parts of paraffin oil, 25～35 parts in essential oil, 13～18 parts of glycerol three tricaprylates, 3～5 parts of lanolines;
The present invention is main curative effect composition with natural Zingiber corallinum Hance essential oil, tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, lanoline, glycerol three tricaprylates, and makes by described method, and various raw materials all can be buied from market.
Rhizoma Zingiberis corallini is a kind of good natural broad spectrum antimicrobicide, its Main Ingredients and Appearance terpinene～4～alcohol, sabinene-3.5～dimethyl cinnamic aldehyde alkynes etc., golden Portugal bacterium and multiple pathogenic dermatophytes there are inhibition, killing action, can improve the mucocutaneous threshold value of resisting to the bad factor, mechanical damage, improve the microcirculation disturbance that physics, chemistry, biological factor cause, the self renewal of enhancing body affected tissue and self-repairing capability play good preventing, therapeutical effect.Can prevent and treat angular stomatitis, cheilosis, lip boil, lip wound.
Tea tree oil is that the expressed white of camellia oleosa seed, room temperature for solid-state oil, have antibacterial action down.
Oleum Ricini has moisture-keeping functions.
Cera Flava has convergence, granulation promoting, pain-relieving functions.
Paraffin oil have moisturize, moisture-keeping functions.
Lanoline has moist, soft skin function.
Glycerol three tricaprylates have the soft skin function of pacifying.
Also can add essence, pigment in right amount, the amount those of ordinary skill of interpolation can according to circumstances be adjusted.
Lip pomade usage of the present invention: directly smear lip, day is coated with 1～2 time, smears continuously and promptly heals in 3～5 days.Effective percentage reaches 100%.
The invention has the beneficial effects as follows compares with common lip pomade has added natural Zingiber corallinum Hance essential oil, can improve the mucocutaneous threshold value of resisting to the bad factor, mechanical damage, improve the microcirculation disturbance that physics, chemistry, biological factor cause, strengthen the self renewal and the self-repairing capability of tissue, can prevent and treat angular stomatitis, cheilosis, lip boil, lip wound.
In order to confirm effectiveness of the present invention, hinder the infective inflammation and the edema that cause at dry lip, chapped lip, lip boil, lip and done following experiment:
1. in-vitro antibacterial experiment of the present invention
Picking Jia Xingrongxuexinglianqiujun, escherichia coli, staphylococcus aureus, B-mode A family Hemolytic streptococcus, be positioned over respectively in the corresponding liquid culture medium (10ml), culture medium put in the 36 degrees Celsius constant incubator cultivate after 24 hours as for examination bacterium liquid (it is 1: 1000 that staphylococcus aureus is diluted with normal saline).
Get sample of the present invention and make and contain that medical material concentration is respectively 160,80,40,20,10,5,2.5,1.25, the pastille culture medium of 0.625mg/ml, with the packing of sterilization test tube, every pipe 1ml.
Get each 0.1ml of bacterium liquid that configures and be inoculated in respectively in the corresponding pastille culture medium, put in the 36 degrees Celsius constant incubator 24 hours.Get respectively manage culture respectively streak inoculation in corresponding solid medium, put in the 36 degrees Celsius constant incubator 24 hours.Observation has or not bacterial growth.Be lower than 5 liquor strength as the minimal inhibitory concentration (MIC) of these these product with the growth bacterium colony.The results are shown in Table 1.
As seen, test sample has killing action to escherichia coli, staphylococcus aureus in concentration 〉=2.5mg/ml, and test sample has killing action to Jia Xingrongxuexinglianqiujun, B-mode A family Hemolytic streptococcus in concentration 〉=10mg/ml.
2. the present invention is to the influence of inflammatory swelling due to the rat paw injection carrageenin
It is heavy to get body weight 150～180g
30 of SD rats are divided into 3 groups at random, 10 every group.Be respectively blank group, test sample group (smearing the anti-inflammatory and analgesic lipstick that 1g contains natural Zingiber corallinum Hance essential oil) and indomethacin matched group, after the administration 1 hour, cause inflammation at the rat toes with sc 1% carrageenin 0.1ml, cause the volumetrical variation of scorching front and back different time foot pawl with rat foot claw volumetry mensuration, per hour one-time continuous is 4 times, so that the volumetrical difference of scorching metapedes pawl is as the swelling degree.
The results are shown in Table 2.
3. skin irritation test of the present invention
Get 20 of adult healthy white rabbit, male and female half and half, body weight are at 2.5～3.0kg, put into the experiment room 3 days of 25 degrees centigrade of temperature, relative humidity 60%～70%, and it is conformed.
Just tame rabbit back spinal column diamond wool cuts off after 3 days, the about 3cm*3cm of unhairing scope.Test sample 1.0g is applied on the hospital gauze of 2.5cm*2.5cm size, spreads on left side skin, cover with cellophane, sealing was applied ointment or plaster 4 hours.The right side is as blank.Observed application site skin in 1,24,48 hour respectively at removing behind the test sample, carry out the dermoreaction scoring by " disinfection technology standard " 2.3.3 skin irritation test invading the exterior 2-11, according to the top value, 2-12 judges skin irritation intensity by table.
The results are shown in Table 3.
An intact skin irritant experiment scoring of table 3 rabbit
As seen, once to contact the total mark value that animal causes the skin irritation reaction be 0 minute to the anti-inflammatory and analgesic lipstick that contains natural Zingiber corallinum Hance essential oil: belong to nonirritant according to " skin irritation strength grading " standard.
The unit of weight of various raw materials is kilogram among all embodiment of specific embodiment (totally 4 examples).
Embodiment 1
(1) takes by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 0.5, tea tree oil 10, Oleum Ricini 10, Cera Flava 10, paraffin oil 8, essential oil 20, glycerol three tricaprylates 10, lanoline 2;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, to be cooled during to 35 ℃, add Rhizoma Zingiberis corallini quintessence oil and stir, cooling is promptly.
Embodiment 2:
(1) takes by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 3, tea tree oil 15, Oleum Ricini 15, Cera Flava 15, paraffin oil 10, essential oil 40, glycerol three tricaprylates 20, lanoline 6;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, to be cooled during to 45 ℃, add Rhizoma Zingiberis corallini quintessence oil, essence 10, stir, cooling gets final product.
Embodiment 3
(1) takes by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 1, tea tree oil 12,12 parts of Oleum Ricini, 12 parts in Cera Flava, 8.5 parts of paraffin oil, 25 parts in essential oil, glycerol three tricaprylates 13, lanoline 3;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, be cooled to 40 ℃, add Rhizoma Zingiberis corallini quintessence oil and stir, cooling promptly.
Embodiment 4
(1) takes by weighing various raw materials by following weight: Rhizoma Zingiberis corallini quintessence oil 2, tea tree oil 14,14 parts of Oleum Ricini, 14 parts in Cera Flava, 9.5 parts of paraffin oil, 35 parts in essential oil, glycerol three tricaprylates 18, lanoline 5;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, be cooled to 42 ℃, add Rhizoma Zingiberis corallini quintessence oil and stir, cooling promptly.
Claims (2)
1. anti-inflammatory and analgesic lipstick that contains natural Zingiber corallinum Hance essential oil is characterized in that preparing as follows:
(1) takes by weighing various raw materials by following parts by weight: 0.5～3 part of Rhizoma Zingiberis corallini quintessence oil, 10～15 parts of tea tree oil, 10～15 parts of Oleum Ricini, 10～15 parts in Cera Flava, 8～10 parts of paraffin oil, 20～40 parts in essential oil, 10～20 parts of glycerol three tricaprylates, 2～6 parts of lanolines;
(2) tea tree oil, Oleum Ricini, Cera Flava, paraffin oil, essential oil, glycerol three tricaprylates, lanoline are heated to congruent melting, stir, be cooled to 35～45 ℃, add Rhizoma Zingiberis corallini quintessence oil and stir, cooling gets final product.
2. the anti-inflammatory and analgesic lipstick that contains natural Zingiber corallinum Hance essential oil according to claim 1, it is characterized in that the described various raw materials in part by weight of step (1) are: 1～2 part of Rhizoma Zingiberis corallini quintessence oil, 12～14 parts of tea tree oil, 12～14 parts of Oleum Ricini, 12～14 parts in Cera Flava, 8.5～9.5 parts of paraffin oil, 25～35 parts in essential oil, 13～18 parts of glycerol three tricaprylates, 3～5 parts of lanolines.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105610532A CN102000004B (en) | 2010-01-29 | 2010-11-19 | Inflammation diminishing and pain relieving lipstick containing zingiber corallinum hance essential oil |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201010102992A CN101862283A (en) | 2010-01-29 | 2010-01-29 | Anti-inflammatory and analgesic lipstick containing natural Zingiber corallinum Hance essential oil |
| CN201010102992.0 | 2010-01-29 | ||
| CN2010105610532A CN102000004B (en) | 2010-01-29 | 2010-11-19 | Inflammation diminishing and pain relieving lipstick containing zingiber corallinum hance essential oil |
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| CN102000004A true CN102000004A (en) | 2011-04-06 |
| CN102000004B CN102000004B (en) | 2011-12-07 |
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| CN201010102992A Pending CN101862283A (en) | 2010-01-29 | 2010-01-29 | Anti-inflammatory and analgesic lipstick containing natural Zingiber corallinum Hance essential oil |
| CN2010105610532A Active CN102000004B (en) | 2010-01-29 | 2010-11-19 | Inflammation diminishing and pain relieving lipstick containing zingiber corallinum hance essential oil |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104606120A (en) * | 2015-02-13 | 2015-05-13 | 南通蛇类治疗研究所 | Nanometer negative ion natural plant lipstick |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1132633A (en) * | 1995-04-04 | 1996-10-09 | 张俊巍 | Application of Glehnia littoralis in health product and cosmetics |
| CN101361938A (en) * | 2008-09-24 | 2009-02-11 | 重庆灵方生物技术有限公司 | Kibe paste containing natural zingiber oil |
-
2010
- 2010-01-29 CN CN201010102992A patent/CN101862283A/en active Pending
- 2010-11-19 CN CN2010105610532A patent/CN102000004B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1132633A (en) * | 1995-04-04 | 1996-10-09 | 张俊巍 | Application of Glehnia littoralis in health product and cosmetics |
| CN101361938A (en) * | 2008-09-24 | 2009-02-11 | 重庆灵方生物技术有限公司 | Kibe paste containing natural zingiber oil |
Non-Patent Citations (1)
| Title |
|---|
| 《中国皮肤性病学杂志》 20050831 曹煜等 特应性皮炎患者皮损表面金黄色葡萄球菌培养及药敏分析 第474-475页 1-2 第19卷, 第8期 2 * |
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| CN101862283A (en) | 2010-10-20 |
| CN102000004B (en) | 2011-12-07 |
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