Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains Difenoconazole and Propineb.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains Difenoconazole and Propineb, wherein Difenoconazole and Propineb weight ratio are 4: 1~1: 64.
The described bactericidal composition that contains Difenoconazole and Propineb, wherein the weight ratio of Difenoconazole and Propineb be preferably 1: 1~1: 32.
The described bactericidal composition that contains Difenoconazole and Propineb, wherein the weight ratio of Difenoconazole and Propineb is more preferably 1: 2~1: 16.
The described bactericidal composition that contains Difenoconazole and Propineb, wherein the weight ratio of Difenoconazole and Propineb is more preferably 1: 4~1: 16.
The described bactericidal composition that contains Difenoconazole and Propineb, wherein the effective active component content accounts for 1~85% of gross weight, is preferably 10~80%.
The described bactericidal composition of Difenoconazole and Propineb that contains is by method well-known in the art, add conventional auxiliary agent and excipient, be processed into acceptable forms on any agricultural chemicals, the wherein excellent formulation of selecting is wetting powder, water dispersible granules, seed treatment etc.
When making wetting powder, composition comprises following constituent content: Difenoconazole 1~50%, Propineb 1~80%, dispersant 5~10%, wetting agent 2~10%, filler 8~90%.
Difenoconazole, Propineb, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into Difenoconazole Wettable propineb powder product.
When making water dispersible granules, composition comprises following constituent content: Difenoconazole 1~50%, Propineb 1~80%, dispersant 3~12%, wetting agent 1~8%, disintegrant 1~10%, filler 10~90%.
Difenoconazole, Propineb, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, obtain the materials of granulating.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes Difenoconazole Propineb water dispersible granules product.
Described dispersant is selected from polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, in phonetic one or more of polyoxyethylene carboxylate, ester polyoxyethylene.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, the soapberry powder.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, the polyethylene glycol.
Described thickener is selected from: one or more in xanthan gum, polyvinyl alcohol, the polyethylene glycol.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, the aluminium chloride.
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, the precipitated calcium carbonate.
Composition of the present invention is mainly used in powdery mildew, anthracnose, spot defoliation, downy mildew, eqpidemic disease and cereal banded sclerotial blight, rice blast of vegetables and fruit tree etc.
Beneficial effect of the present invention:
(1) present composition effective active composition Difenoconazole and Propineb belong to the bactericide of two kinds of different mechanisms of action, and both are mixed mutually and can produce conflict;
(2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little;
(3) the present invention not with an organic solvent is not difficult for producing poisoning, is convenient to transportation and storage;
(4) present composition has special efficacy to eqpidemic disease, downy mildew, spot defoliation and rice blast, the banded sclerotial blight of vegetables and fruit tree.
Embodiment
To further instruction of the present invention, the percentage among the embodiment all is weight percentage below in conjunction with embodiment, but the present invention is not limited thereto.
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one: Difenoconazole and Propineb are composite to be provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation cucumber downy mildew Toxicity Determination test medicine.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament cucumber downy mildew.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR<0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR>1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively Difenoconazole and Propineb shared ratio in combination
A is a Difenoconazole
B is a Propineb
Result of the test is as shown in table 1:
Table 1 Difenoconazole, Propineb and composite toxicity test analysis of results table thereof to cucumber downy mildew
As shown in Table 1, Difenoconazole, Propineb are to the EC of cucumber downy mildew
50Be respectively 0.18mg/L and 57.51mg/L.The virulence of Difenoconazole is higher than the virulence of Propineb.Difenoconazole and Propineb were mixed in the scope at 4: 1~1: 64 and all show obvious synergistic effect.Wherein Difenoconazole and Propineb mixed synergies in 1: 1~1: 32 scope is comparatively desirable, and the effect that was mixed in the scope at 1: 2~1: 16 is particularly outstanding.
Implementation of an application example two the implementation of Formulation Example
Embodiment 180% Difenoconazole Propineb water dispersible granules
Difenoconazole 8%, Propineb 72%, lauryl sodium sulfate 4%, lignosulfonates 3%, alkylphenol-polyethenoxy are phonetic 3%, starch adds to 100%, mixed 80% Difenoconazole Propineb water dispersible granules.
Embodiment 266% Difenoconazole Propineb water dispersible granules
Difenoconazole 6%, Propineb 60%, polycarboxylate 3%, polyoxyethylene carboxylate 3%, lauryl sodium sulfate 4%, sodium bicarbonate 3%, starch 10%, bentonite add to 100%, the mixed 66% Difenoconazole Propineb water dispersible granules that gets.
Embodiment 345% Difenoconazole Propineb water dispersible granules
Difenoconazole 5%, Propineb 40%, alkylphenol-polyethenoxy are phonetic 5%, dodecyl benzene sulfonate 3%, gelatin 2%, starch 5%, bentonite add to 100%, mixed 45% Difenoconazole Propineb water dispersible granules.
Embodiment 430% Difenoconazole Propineb water dispersible granules
Difenoconazole 15%, Propineb 15%, alkylphenol-polyethenoxy are phonetic 4%, DBSA 4%, starch 8%, urea 5%, diatomite add to 100%, mixed 30% Difenoconazole Propineb water dispersible granules.
Embodiment 580% Difenoconazole Wettable propineb powder
Difenoconazole 10%, Propineb 70%, polycarboxylate 5%, neopelex 3%, soapberry powder 2%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 80% Difenoconazole Wettable propineb powder.
Embodiment 666% Difenoconazole Wettable propineb powder
Difenoconazole 2%, Propineb 64%, lignosulfonates 5%, spaonin powder 3%, starch 7%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 66% Difenoconazole Wettable propineb powder.
Embodiment 750% Difenoconazole Wettable propineb powder
Difenoconazole 10%, Propineb 40%, alkylphenol-polyethenoxy are phonetic 4%, neopelex 3%, white carbon 5%, kaolin add to 100%, and mixture carries out comminution by gas stream, makes 50% Difenoconazole Wettable propineb powder.
Embodiment 834% Difenoconazole Wettable propineb powder
Difenoconazole 2%, Propineb 32%, lignosulfonates 5%, wetting and penetrating agent F3%, white carbon 7%, bentonite add to 100%, and mixture carries out comminution by gas stream, make 34% Difenoconazole Wettable propineb powder.
Embodiment uses triphenylmethyl ether methyl cyclic-azole and the Propineb and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
This experimental establishment is in the Liquan County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 70% Wettable propineb powder (commercial), 25% Difenoconazole missible oil (commercial).
The investigation alternaria leaf spot of apple state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 3 times.Investigated alternaria leaf spot of apple feelings index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the third time.Experimental result is as follows:
Table 2 Difenoconazole, Propineb and the composite control alternaria leaf spot of apple test of pesticide effectiveness thereof
As can be seen from Table 2, can effectively prevent and treat alternaria leaf spot of apple after Difenoconazole and Propineb are composite, control efficiency all is better than contrasting medicament, and the lasting period is long.In the test scope of medication, the target crop is had no adverse effects.
Implementation of an application example four: Difenoconazole and Propineb and the composite control cucumber downy mildew test of pesticide effectiveness thereof
This experimental establishment is in the Qian County, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 70% Wettable propineb powder (commercial), 25% Difenoconazole missible oil (commercial).
The investigation cucumber downy mildew state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated the cucumber downy mildew disease index respectively and calculated preventive effect in 7 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 3 Difenoconazole, Propineb and the composite control cucumber downy mildew test of pesticide effectiveness thereof
As can be seen from Table 3, energy effectively preventing cucumber downy mildew after Difenoconazole and Propineb are composite, control efficiency all is better than contrasting medicament, and dosage is little, and the lasting period is long.In the test scope of medication, the target crop there is not harm.
Implementation of an application example five: Difenoconazole, Propineb and the composite early blight of tomato test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in the Jinta County, Gansu Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 70% Wettable propineb powder (commercial), 25% Difenoconazole missible oil (commercial).
Investigation early blight of tomato state of an illness radix, total number of sheets, the sick number of sheets and sick leaf-size class number before the medicine, in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively and calculates preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
Table 4 Difenoconazole, Propineb and the composite early blight of tomato test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 4, can effectively prevent and treat early blight of tomato after Difenoconazole and Propineb are composite and take place, control efficiency all is better than contrasting medicament, in this test scope of medication the target crop is had no adverse effects.
Implementation of an application example six: Difenoconazole, Propineb and the composite control rice blast test of pesticide effectiveness thereof
This experimental establishment is in the Yongde County, Yunnan Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 70% Wettable propineb powder (commercial), 25% Difenoconazole missible oil (commercial).
Investigation rice blast state of an illness radix, total number of sheets, the sick number of sheets and sick leaf-size class number before the medicine, in the their early stage dispenser, dispenser in per 7 days once is total to dispenser 2 times, investigates disease index respectively and calculates preventive effect in 7 days, 14 days after the dispenser for the second time.Experimental result is as follows:
The sick test of pesticide effectiveness of table 5 Difenoconazole, Propineb and composite control rice blast thereof
As can be seen from Table 5, can effectively prevent and treat rice blast after Difenoconazole and Propineb are composite and take place, control efficiency all is better than contrasting medicament, in this test scope of medication the target crop is had no adverse effects.And rice sheath blight disease had good preventive effect, preventive effect all reaches more than 90%.