CN101995364A - Method and device for detecting blood viscosity and hematocrit by using one instrument - Google Patents

Method and device for detecting blood viscosity and hematocrit by using one instrument Download PDF

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Publication number
CN101995364A
CN101995364A CN2009100908097A CN200910090809A CN101995364A CN 101995364 A CN101995364 A CN 101995364A CN 2009100908097 A CN2009100908097 A CN 2009100908097A CN 200910090809 A CN200910090809 A CN 200910090809A CN 101995364 A CN101995364 A CN 101995364A
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sample
pipe support
blood
slideway
sample pipe
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CN101995364B (en
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陈生
肖继昌
董成刚
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Beijing Mindray Medical Instrument Co ltd
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Beijing Precil Instrument Co Ltd
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Abstract

The invention relates to a method and a device for detecting blood viscosity and hematocrit by using one instrument. In the invention, full-automatic detection equipment, including a stirring pin device, a sample loading pin device, a capillary viscosity measurement device, a rotary type blood rheological measurement device, a hematocrit scanning measurement device, a computer device based automatic control circuit and a matched program of the automatic control circuit is used. The detection method comprises the following steps of: collecting a patient blood sample, carrying out anticoagulant processing, injecting into a sample tube, and centrifuging; putting the sample tube in a sample tube frame, conveying the sample tube frame to a hematocrit test position for detecting, and storing hematocrit data; conveying the sample tube frame to a blood viscosity test position for detecting plasm viscosity and storing data; stirring the blood sample into whole blood by the stirring pin device, and reading the blood viscosity data by the rotary type blood rheological measurement device; and processing the detected data by a resolving processor. By using the full-automatic detection manner disclosed in the invention, operators avoid contacting the patient blood sample directly and cannot be polluted, all the processes of sample loading process, detection process and cleaning process are all accomplished by instruments automatically, thereby improving the detection speed and accuracy of clinical examination.

Description

A kind of blood viscosity, a long-pending machine method for measuring and the equipment of blood pressure
Technical field
The present invention relates to a kind of blood viscosity, a long-pending machine method for measuring and the equipment of blood pressure, this method is used a kind of full-automatic sensing equipment, and described full-automatic sensing equipment includes mixing needle device, sample needle device, rotary hemorheology measurement mechanism, hematocrit sweep measuring device, automatic control circuit and matcher.
Background technology
Chinese patent 200520104155.6 discloses a kind of fluid viscosity measurement mechanism based on the application of sample capillary pipeline, a frame is arranged, this frame is provided with the sample needle erecting frame, fix a capillary type sample needle on the described sample needle erecting frame, this sample needle is communicated with a sample-adding pump by an application of sample pipeline, on described application of sample needle body or described application of sample pipeline, a pressure transducer is set, this pressure transducer resolves processor and is electrically connected with one by data line, the described processor that resolves is electrically connected with described sample-adding pump input end by control line, below described capillary type sample needle, the sample cup fixator is set, is provided with tested liquid sample cup and tested liquid sample cup in the described sample cup fixator.The utlity model has online detection, can obtain testing result, data advantage accurately and reliably immediately.But this patent is energy measurement plasma viscosity or whole blood viscosity only.Can't measure plasma viscosity, whole blood viscosity and erythrocyte hematocrit by a machine, therefore, need to propose a kind of new blood viscosity, a long-pending machine method for measuring and the equipment of blood pressure.
Summary of the invention
The object of the present invention is to provide a long-pending machine method for measuring and the equipment of a kind of blood viscosity, blood pressure, described full-automatic sensing equipment includes mixing needle device, sample needle device, capillary viscosity measurement mechanism, rotary hemorheology measurement mechanism, hematocrit sweep measuring device, based on the automatic control circuit and the matcher of computer installation; Full-automatic detection mode of the present invention; operating personnel have been avoided because of directly contacting contaminated with patient's blood sample; protected greatly that the operator's is healthy; all application of sample program, test procedure, cleaning procedure are finished automatically by instrument, have improved the test speed and the accuracy of clinical examination greatly.
An object of the present invention is to realize: a kind of blood viscosity, the long-pending machine method for measuring of blood pressure by following technical proposals, use a kind of full-automatic sensing equipment, described full-automatic sensing equipment includes mixing needle device, sample needle device, capillary viscosity measurement mechanism, rotary hemorheology measurement mechanism, hematocrit sweep measuring device, based on the automatic control circuit and the matcher of computer installation; Determination step is:
A, the anti-freezing of collection patient venous samples can are handled in the injecting sample pipe, generate anticoagulated whole blood, described sample tube mark are handled, with the anticoagulated whole blood centrifugal treating;
B, the blood sample sample tube after the centrifugal treating is put into the sample pipe support, carry the sample pipe support to arrive the hematocrit test position, hematocrit sweep measuring device starts also scanning blood sample, measures and also preserves the packed cell volume data;
C, order conveying device are transported to the blood viscosity test position with the sample pipe support, start the sample needle device, extract the plasma sample in the described sample tube, use the capillary viscosity measurement mechanism to measure described plasma sample viscosity and preserve this viscosity data; Again used plasma sample is recycled in the sample tube;
D, startup mixing needle device stir into the whole blood state with blood sample; Order sample needle device is pressed the examination criteria consumption and is drawn blood sample from described sample pipe support, inject rotary hemorheology measurement mechanism, and rotary hemorheology measurement mechanism reads the whole blood viscosity data automatically;
E, utilization are resolved processor the data of being measured are handled, and generate test report according to the patient information of being imported.
Another object of the present invention is realized by following technical proposals: a kind of blood viscosity, the long-pending full-automatic sensing equipment of blood pressure, a support is arranged, support is provided with mixing needle device, sample needle device, rotary hemorheology measurement mechanism, capillary viscosity measurement mechanism, based on the automatic control circuit and the matcher of computer installation, described support middle part is provided with a testing stand, one side of this testing stand is provided with sample pipe support input slideway, and opposite side is provided with sample pipe support output slideway; The outlet of described sample pipe support input slideway is communicated with the inlet of a sample pipe support stepping slideway, and the outlet of described sample pipe support stepping slideway is communicated with the inlet of described sample pipe support output slideway; Set gradually rotary hemorheology measurement mechanism, rinse bath device on the described testing stand, described testing stand top is provided with two-dimentional mobile working device, this two dimension mobile working device comprises transverse moving mechanism, vertically to travel mechanism, described mixing needle device and sample needle device are installed on this two dimension mobile working device; The first test position of described sample pipe support stepping slideway is provided with hematocrit sweep measuring device; Below the described sample pipe support input slideway V shape propulsive mechanism is set, the exit position of described sample pipe support stepping slideway is provided with the pivoted arm output mechanism; Below the described sample pipe support stepping slideway pivoted arm propulsive mechanism is set; Described sample needle device is connected with automatic application of sample pipeline.
Compared with the prior art the present invention has following advantage:
1, the present invention uses an instrument, can measure plasma viscosity, whole blood viscosity, also can measure packed cell volume; Directly use the centrifugal and test of blood sampling test tube, reduced the use amount of test tool, reduced the cleaning amount of test tool.
2, the present invention has overcome the defective of prior art, and automatic application of sample, detection automatically, the automatic cleaning are incorporated on the instrument, has realized application of sample, detection, cleaning, removal waste fluid, dry full-automatic, has improved the test speed of clinical examination greatly.
3, full-automatic detection mode of the present invention makes operating personnel avoid having protected the healthy of operator greatly because of directly contacting contaminated risk with patient's blood sample, has simultaneously also avoided the operator pollution of blood sample to be influenced the accuracy of detection.
4, the present invention is modified into the long-pending value of manual read's pressure by the test of equipment autoscan, has increased the automaticity of test operation.
Description of drawings
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 is a full-automatic sensing equipment structural representation of the present invention
Fig. 2 is plan structure figure of the present invention (the A-A cut-open view of Fig. 1)
Fig. 3 is sample pipe support primary importance figure of the present invention
Fig. 4 is sample pipe support second place figure of the present invention
Fig. 5 is sample pipe support the 3rd location drawing of the present invention
Fig. 6 is a hematocrit sweep measuring structure drawing of device of the present invention
Fig. 7 is a two-dimentional mobile working structure drawing of device of the present invention
Fig. 8 is pivoted arm pusher composition of the present invention (the B-B cut-open view of Fig. 5)
Fig. 9 is a V shape propulsive mechanism synoptic diagram of the present invention
Figure 10 is a V shape propulsive mechanism of the present invention longitudinal profile synoptic diagram (the C-C cut-open view of Fig. 9)
Figure 11 is sample pipe support plan structure figure
Embodiment
Embodiment one:
Blood viscosity of the present invention, the long-pending machine method for measuring of blood pressure, use a kind of full-automatic sensing equipment, described full-automatic sensing equipment includes mixing needle device, sample needle device, capillary viscosity measurement mechanism, rotary hemorheology measurement mechanism, hematocrit sweep measuring device, based on the automatic control circuit and the matcher of computer installation; The detailed structure of full-automatic sensing equipment can be referring to embodiment two disclosed contents, and determination step of the present invention is:
A, the anti-freezing of collection patient venous samples can are handled in the injecting sample pipe, generate anticoagulated whole blood, and this sample tube mark is handled; Normally from the about 5ml of vein venous blood samples, put into anti-coagulants in the sample tube in advance, shake up anti-freezing then; With the anticoagulated whole blood centrifugal treating, centrifugal force 2300g, (3000 rev/mins) centrifugal 30 minutes; Described sample tube mark is handled and is meant the adhesive sticker mark is arranged on the sample tube, the adhesive sticker label record testing sequence, patient information; Described adhesive sticker mark supports electron scanning to handle; It can also be the electronic marker (for example the barcode label form sprays mark etc. on sample tube) of making other form on sample tube that described sample tube mark is handled;
B, the blood sample sample tube after the centrifugal treating is put into the sample pipe support, carry the sample pipe support to arrive the hematocrit test position, hematocrit sweep measuring device starts also scanning blood sample sample tube, measures and also preserves the packed cell volume data; The content of described scanning comprises testing sequence, patient information, packed cell volume data; Described mensuration and preservation packed cell volume data are that the employing photoelectric switching circuit reads the transmission data on the sample hose automatically;
C, order conveying device are transported to the blood viscosity test position with the sample pipe support, start the sample needle device, extract the plasma sample in the described sample tube, use the capillary viscosity measurement mechanism to measure described plasma sample viscosity and preserve this viscosity data; Again used plasma sample is recycled in this sample tube;
D, startup mixing needle device stir into the whole blood state with this blood sample; Order sample needle device is pressed the examination criteria consumption and is drawn the whole blood blood sample from this blood sample, inject rotary hemorheology measurement mechanism, and rotary hemorheology measurement mechanism reads the whole blood viscosity data automatically;
E, utilization are resolved processor the data of being measured are handled, and generate test report according to the patient information of being imported.
F, order sample needle device clean sample needle, mixing needle, rotary hemorheology measurement mechanism, and next test process is carried out in circulation then.Blood sample of the every suction of sample needle all carries out cleaning operation one time.
The detailed content that the capillary viscosity measurement mechanism that relates in the present embodiment, plasma viscosity are measured can not be described in detail referring to China Patent No. 200510092821.3 disclosed contents.
Method of the present invention is incorporated into automatic application of sample, detection automatically, the automatic cleaning on the instrument, automatic control by computer installation, realize application of sample, detection, cleaning, removal waste fluid, dry full-automatic, improved the test speed of clinical examination greatly; Operating personnel have been avoided because of directly contacting contaminated risk with patient's blood sample, also avoided the operator pollution of blood sample to be influenced the accuracy of detection simultaneously.
Embodiment two:
Referring to Fig. 1, Fig. 2 (Fig. 1 right part is a broken section), blood viscosity of the present invention, the long-pending full-automatic sensing equipment of blood pressure, a box support 1 is arranged, support is provided with mixing needle device, sample needle device, rotary hemorheology measurement mechanism, capillary viscosity measurement mechanism, based on the automatic control circuit and the matcher of computer installation, described support middle part is provided with a testing stand 2, one side (right side) of this testing stand is provided with sample pipe support input slideway 3, and opposite side is provided with sample pipe support output slideway 5; The outlet of described sample pipe support input slideway is communicated with the inlet of a sample pipe support stepping slideway 4, and the outlet of described sample pipe support stepping slideway is communicated with the inlet of described sample pipe support output slideway; Set gradually rotary hemorheology measurement mechanism 201, rinse bath device 202 on the described testing stand, described testing stand top is provided with two-dimentional mobile working device 6, this two dimension mobile working device comprises transverse moving mechanism, vertically to travel mechanism, described mixing needle device and sample needle device are installed on this two dimension mobile working device; The first test position of described sample pipe support stepping slideway is provided with hematocrit sweep measuring device 7; Below the described sample pipe support input slideway V shape propulsive mechanism 8 is set, the exit position of described sample pipe support stepping slideway is provided with pivoted arm output mechanism 9; Below the described sample pipe support stepping slideway pivoted arm propulsive mechanism 10 is set; Described sample needle device is connected with automatic application of sample pipeline.
Referring to Fig. 8, Figure 11 (Fig. 8 is a sample pipe support stepping slideway cut-open view), in the present embodiment, sample pipe support 101 is the plastic processing frames that are in-line, position, 10 holes 102 is set on it, Kong Weizhong can insert the sample tube 106 of regular size, the front of each position, hole is provided with a breach 103, is used to adjust the detection position on the sample tube face of cylinder.Sample pipe support bottom is provided with stepping tooth bar 104, and sample pipe support the right is provided with leads tenon 105, and this is led tenon and cooperates with the guide groove 303 that the sample pipe support is imported on the slideway.
Referring to Fig. 1, Fig. 2, Fig. 3, in the present embodiment, sample pipe support input slideway 3 is plane slideways, its middle part is provided with two parallel propelling elongated slots 304, its both sides are provided with grade limit 301,302, a guide groove 303 is set on the shelves limit, right side, leads tenon 105 coupling on this guide groove and the sample pipe support, prevent that the sample pipe support from toppling over when the input slideway moves.Sample pipe support input slideway front end is a sample pipe support loading port 305, and sample pipe support input slideway rear end is the outlet of sample pipe support, and the outlet of this input slideway is communicated with two orthogonal thereto linkings of slideway with the inlet of a sample pipe support stepping slideway.When the sample pipe support leaves the outlet of input slideway, directly enter sample pipe support stepping slideway.
Referring to Fig. 1, Fig. 9, Figure 10, in the present embodiment, V shape propulsive mechanism 8 is set below the sample pipe support input slideway, this propulsive mechanism comprises horizontal guide rail mechanism, synchronous belt haulage gear, advances support body.Horizontal guide rail mechanism is two guide pillars 801 that be arranged in parallel.This guide pillar is installed on the support 1 by supporting plate 802.Advance support body 803 to be provided with two slide openings, be slidingly connected by this slide opening and guide pillar, advance the support body upper end to be symmetrical arranged two fork arms 804, propelling elongated slot 304 couplings on this fork arm and the sample pipe support input slideway are installed.The synchronous belt haulage gear is by synchronous cog belt 805, stepper motor 808, main synchronizing wheel 806, form from synchronizing wheel 807, stepper motor is fixed on the support, its output shaft is connected (not showing among the figure) with main synchronizing wheel, main synchronizing wheel and be installed on the support by supporting plate 809 from synchronizing wheel advances support body bottom and synchronous cog belt to fix.Stepper motor can drive and advance support body to move back and forth along guide pillar, and two fork arms on it promote the sample pipe support and move to the back-end from sample pipe support input slideway front end, in it being sent into sample pipe support stepping slideway.
Referring to Fig. 1, Fig. 2, Fig. 3, in the present embodiment, sample pipe support output slideway 5 is plane slideways, its both sides are provided with grade limit 501,502, sample pipe support output slideway front end is that sample pipe support dress is collected mouth 503, sample pipe support output slideway rear end is a sample pipe support inlet 504, and the inlet of this input slideway is communicated with two orthogonal thereto linkings of slideway with the outlet of a sample pipe support stepping slideway.When the sample pipe support leaves the outlet of described stepping slideway, directly enter sample pipe support output slideway.
Referring to Fig. 3, Fig. 4, Fig. 5, in the present embodiment, sample pipe support stepping slideway 4 is slideways of a strip, this slideway one side is provided with grade limit 401, this slideway (the right) on one side is connected with sample pipe support input slideway, another side (left side) and sample pipe support output slideway is connected, and sample pipe support stepping slideway and sample pipe support are imported slideway, sample pipe support and exported that slideway is vertical to be provided with, and three slideways are arranged on the same surface level.
Referring to Fig. 4, Fig. 5, Fig. 8 (Fig. 8 is a sample pipe support stepping slideway cut-open view), pivoted arm propulsive mechanism 10 is set below the sample pipe support stepping slideway, this propulsive mechanism comprises main synchronizing wheel, from synchronizing wheel, rotation driving lever, synchronous belt 114, drive motor.Coaxial on the main synchronizing wheel 111 a rotation driving lever 110 is set, coaxial another rotation driving lever 110 that is provided with from the synchronizing wheel 112, two synchronizing wheels are installed on the support by back shaft, drive motor is a stepper motor 113, its output shaft drives with main synchronizing wheel and is connected, in the present embodiment, drive motor is connected with main synchronizing wheel with belt pulley by driving belt.Two driving levers are set by hole 403 on the base plate 402 of sample pipe support stepping slideway, the rotation driving lever can screw in, screw out by the hole along this driving lever.When the rotation driving lever screws in, stepping tooth bar 104 engagements of this rotation driving lever and sample pipe support bottom.Under the driving of drive motor, in a moving week of rotation driving lever revolution, the sample pipe support moves forward a step-length under the rotation driving lever promotes.
Referring to Fig. 4, Fig. 5, in the present embodiment, sample pipe support stepping slideway outlet position is provided with pivoted arm output mechanism 9, the pivoted arm output mechanism comprises: two pivot arms 901, trace 905, drive motor, pivoted arm erecting frame 906, the pivot arm front portion is that working arm 902 middle parts are turning axles 903, the rear portion is a transmission arm 904, one of them turning axle is connected (not showing among the figure) with the output shaft of drive motor, two transmission arms link together by trace, make two pivot arms keep being synchronized with the movement.When the pivoted arm output mechanism is in reset mode, working arm and sample pipe support stepping slideway shelves limit keeping parallelism, when the sample pipe support moves to sample pipe support stepping slideway exit position, drive motor starts, working arm turns clockwise, and working arm turns to and sample pipe support stepping slideway shelves limit plumbness, and the sample pipe support is pushed into sample pipe support output slideway 5, the drive motor backward rotation, working arm resets.
Referring to Fig. 2, Fig. 6, in the present embodiment, the first test position of sample pipe support stepping slideway is provided with hematocrit sweep measuring device 7, and hematocrit sweep measuring device comprises: sample hose transposition driving mechanism, hematocrit scanner, elevating mechanism.Sample hose transposition driving mechanism is made of swinging mounting 701 drive motor 705, driving pulley 702, driven pulley 704, friction belt 703; Swinging mounting is installed on the fixed frame 712 by axis of swing 711; Fixed frame and support are installed, and axis of swing is connected with a stepper motor power; Elevating mechanism is made of fixed support 708, lifting support 707, lifting screw 710, stepper motor 709; Fixed support and support are installed together, and a gathering sill is set on the fixed support, and lifting support rear end and gathering sill are slidingly connected; Hematocrit scanner 706 is arranged on the lifting support front end.The lighting transistor circuit and the photoelectric switching circuit that comprise complete configuration in the used hematocrit scanner, comprise an infrarede emitting diode in the lighting transistor circuit, comprise an infrared receiving crystal pipe in the photoelectric switching circuit, sample tube 106 1 sides are provided with infrarede emitting diode, a corresponding side is provided with infrared receiving crystal pipe (owing to be prior art, not showing among the figure).
Referring to Fig. 1, Fig. 7, in the present embodiment, set gradually rotary hemorheology measurement mechanism 201, rinse bath device 202 on the described testing stand.
Referring to Fig. 1, Fig. 7, in the present embodiment, described testing stand top is provided with two-dimentional mobile working device 6, and this two dimension mobile working device comprises transverse moving mechanism, vertically to travel mechanism, and described mixing needle device and sample needle device are installed on this two dimension mobile working device.Transverse moving mechanism is made of horizontal guide rail 601, stepper motor, synchronous cog belt mechanism 602, horizontal tray 603; Synchronous cog belt mechanism comprises that a main synchronizing wheel, one are provided with a synchronous cog belt from synchronizing wheel on two synchronizing wheels, and stepper motor is fixed on the support, and its output shaft is connected with main synchronizing wheel; Horizontal tray top and horizontal guide rail are slidingly installed, and its underpart and synchronous cog belt are fixed; Horizontal tray can move back and forth along horizontal guide rail under step motor drive; Described horizontal guide rail adopts cylindrical slideway.Be provided with two on the horizontal tray vertically to travel mechanism, vertically constitute by upright guide rail 604, stepper motor 605, synchronous cog belt mechanism 606, vertical carriage 607 to travel mechanism; Described upright guide rail adopts cylindrical slideway, and synchronous cog belt mechanism 606 comprises that a main synchronizing wheel, one from synchronizing wheel, are provided with a synchronous cog belt on two synchronizing wheels.A vertical vertical carriage in travel mechanism is installed sample needle device 608, and another is the vertical carriage installation mixing needle device 609 in travel mechanism vertically.Vertically basic identical to the structure and the transverse moving mechanism of travel mechanism, be not described in detail.Sample needle device or mixing needle device can move up and down along upright guide rail under step motor drive.
In the present embodiment, the sample needle device is connected with the capillary viscosity measurement mechanism by automatic application of sample pipeline; The detailed content of the detailed content of related capillary viscosity measurement mechanism, automatic application of sample pipeline in the present embodiment, can be referring to China Patent No. 200510092821.3 disclosed contents, belong to the routine techniques content based on computer installation automatic control circuit and matcher, be not described in detail; The concrete structure of rotary hemorheology measurement mechanism can not be described in detail with reference to the LBY-N6C fully automatic blood flow graph of selling on the market.The sensor and the control circuit thereof of the detection movement position that relates in the present embodiment belong to the routine techniques content, are not described in detail.
Operation logic of the present invention is as follows:
Gathering the anti-freezing of patient's venous samples can handles in the injecting sample pipe, generate anticoagulated whole blood, with the anticoagulated whole blood centrifugal treating, blood sample sample tube after the centrifugal treating is put into the sample pipe support, operating personnel are manual to put into blood viscosity of the present invention with the sample pipe support, sample pipe support input slideway inlet 305 on the long-pending full-automatic sensing equipment of blood pressure, (referring to accompanying drawing 2,3,4,5), after the sample pipe support is arrived in Equipment Inspection, automatically open V shape propulsive mechanism 8, this propulsive mechanism is transported to sample pipe support stepping slideway 4 with the sample pipe support, after the sample pipe support is arrived in Equipment Inspection, opens pivoted arm propulsive mechanism 10 automatically, simultaneously, the V shape propulsive mechanism resets.The pivoted arm propulsive mechanism is transported to the sample pipe support according to step-by-step system and reaches the hematocrit test position, after first sample tube of Equipment Inspection to the sample pipe support, hematocrit sweep measuring device starts, wherein, the swing span of sample hose transposition driving mechanism tilts to move to the sample tube direction, friction belt 703 contacts with the sample tube surface, the driving sample tube is rotated, simultaneously, the hematocrit scanner to sample tube scanning one time, is sent to the electronic marker content on the sample tube (testing sequence, patient information) in the storer of computing machine from bottom to top; Been scanned for the first time, sample hose transposition driving mechanism is thrown off with sample tube, and the hematocrit scanner carries out scanning second time to sample tube from bottom to top, measures the packed cell volume data, and is sent to the interior preservation of storer of computing machine.After the been scanned, the pivoted arm propulsive mechanism is pushed ahead a step-length again with the sample pipe support for the second time, and the hematocrit scanner is implemented test to second sample tube; When first sample tube of Equipment Inspection to the sample pipe support arrives hemorheology measurement mechanism position, the two-dimentional mobile working device of testing stand top starts, referring to Fig. 7, the sample needle device starts, sample needle extend into and extracts plasma sample in the sample tube, starts the capillary viscosity measurement mechanism and measures described plasma sample viscosity and preserve this viscosity data; Again used plasma sample is recycled in this sample tube; Then, the mixing needle device starts, and mixing needle extend in the sample tube, and blood sample in this sample tube is stirred into the whole blood state; Order the sample needle device to draw the whole blood blood sample again from this sample tube, be injected into rotary hemorheology measurement mechanism 201, rotary hemorheology measurement mechanism reads the whole blood viscosity data automatically; Equipment cleans sample needle, mixing needle, rotary hemorheology measurement mechanism automatically, and next test process is carried out in circulation then.After the blood sample in first sample tube is finished whole test events, the pivoted arm propulsive mechanism is pushed ahead a step-length according to step-by-step system again with the sample pipe support, when the sample pipe support arrives the exit position of sample pipe support stepping slideway, equipment is devoted oneself to work according to the detection signal startup pivoted arm output mechanism of sensor, two pivot arms in the pivoted arm output mechanism rotate, and the sample pipe support is pushed into sample pipe support output slideway.The testing process of a sample pipe support finishes, and other sample pipe support carries out continuously according to above-mentioned flow process.

Claims (7)

1. a blood viscosity, blood pressure amass a machine method for measuring, it is characterized in that: use a kind of full-automatic sensing equipment, described full-automatic sensing equipment includes mixing needle device, sample needle device, capillary viscosity measurement mechanism, rotary hemorheology measurement mechanism, hematocrit sweep measuring device, based on the automatic control circuit and the matcher of computer installation; Determination step is:
A, the anti-freezing of collection patient venous samples can are handled in the injecting sample pipe, generate anticoagulated whole blood, described sample tube mark are handled, with the anticoagulated whole blood centrifugal treating;
B, the blood sample sample tube after the centrifugal treating is put into the sample pipe support, carry the sample pipe support to arrive the hematocrit test position, hematocrit sweep measuring device starts also scanning blood sample, measures and also preserves the packed cell volume data;
C, order conveying device are transported to the blood viscosity test position with the sample pipe support, start the sample needle device, extract the plasma sample in the described sample tube, use the capillary viscosity measurement mechanism to measure described plasma sample viscosity and preserve this viscosity data; Again used plasma sample is recycled in the sample tube;
D, startup mixing needle device stir into the whole blood state with blood sample; Order sample needle device is pressed the examination criteria consumption and is drawn blood sample from described sample pipe support, inject rotary hemorheology measurement mechanism, and rotary hemorheology measurement mechanism reads the whole blood viscosity data automatically;
E, utilization are resolved processor the data of being measured are handled, and generate test report according to the patient information of being imported.
2. a blood viscosity, blood pressure amass full-automatic sensing equipment, a support is arranged, support is provided with mixing needle device, sample needle device, rotary hemorheology measurement mechanism, capillary viscosity measurement mechanism, based on the automatic control circuit and the matcher of computer installation, it is characterized in that: described support middle part is provided with a testing stand, one side of this testing stand is provided with sample pipe support input slideway, and opposite side is provided with sample pipe support output slideway; The outlet of described sample pipe support input slideway is communicated with the inlet of a sample pipe support stepping slideway, and the outlet of described sample pipe support stepping slideway is communicated with the inlet of described sample pipe support output slideway; Set gradually rotary hemorheology measurement mechanism, rinse bath device on the described testing stand, described testing stand top is provided with two-dimentional mobile working device, this two dimension mobile working device comprises transverse moving mechanism, vertically to travel mechanism, described mixing needle device and sample needle device are installed on this two dimension mobile working device; The first test position of described sample pipe support stepping slideway is provided with hematocrit sweep measuring device; Below the described sample pipe support input slideway V shape propulsive mechanism is set, the exit position of described sample pipe support stepping slideway is provided with the pivoted arm output mechanism; Below the described sample pipe support stepping slideway pivoted arm propulsive mechanism is set; Described sample needle device is connected with automatic application of sample pipeline.
3. full-automatic sensing equipment according to claim 2 is characterized in that: the V shape propulsive mechanism below the described sample pipe support input slideway comprises horizontal guide rail mechanism, synchronous belt haulage gear, advances support body; Advance the support body upper end to be symmetrical arranged two fork arms, advance support body bottom and synchronous cog belt to fix, the synchronous belt haulage gear by synchronous cog belt, stepper motor, main synchronizing wheel, form stepper motor output shaft and main synchronizing wheel from synchronizing wheel.
4. full-automatic sensing equipment according to claim 3, it is characterized in that: described pivoted arm output mechanism comprises two pivot arms, trace, drive motor, pivoted arm erecting frame, the pivot arm front portion is a working arm, the middle part is a turning axle, the rear portion is a transmission arm, one of them turning axle is connected with the output shaft of drive motor, and two transmission arms link together by trace.
5. full-automatic sensing equipment according to claim 4, it is characterized in that: the pivoted arm propulsive mechanism below the described sample pipe support stepping slideway comprises main synchronizing wheel, from synchronizing wheel, rotation driving lever, synchronous belt, drive motor, coaxial on the main synchronizing wheel rotation driving lever is set, coaxial another rotation driving lever that is provided with from the synchronizing wheel.
6. full-automatic sensing equipment according to claim 5 is characterized in that: described hematocrit sweep measuring device comprises sample hose transposition driving mechanism, hematocrit scanner, elevating mechanism; Sample hose transposition driving mechanism is made of swinging mounting, drive motor, driving pulley, driven pulley, friction belt; Elevating mechanism is made of fixed support, lifting support, lifting screw, stepper motor.
7. full-automatic sensing equipment according to claim 6 is characterized in that: the transverse moving mechanism in the described two-dimentional mobile working device is made of horizontal guide rail, stepper motor, synchronous cog belt mechanism, horizontal tray; Synchronous cog belt mechanism comprises that a main synchronizing wheel, one are provided with a synchronous cog belt from synchronizing wheel on two synchronizing wheels, and horizontal tray top and horizontal guide rail are slidingly installed, and its underpart and synchronous cog belt are fixed; Vertically constituting by upright guide rail, stepper motor, synchronous cog belt mechanism, vertical carriage in the described two-dimentional mobile working device to travel mechanism.
CN2009100908097A 2009-08-11 2009-08-11 Method and device for detecting blood viscosity and hematocrit by using one instrument Active CN101995364B (en)

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CN102866083A (en) * 2012-09-29 2013-01-09 北京普利生仪器有限公司 Blood pressure measuring method
CN103364577A (en) * 2012-03-29 2013-10-23 深圳市开立科技有限公司 Feeding and sampling device for hematology analyzer
CN104931460A (en) * 2014-03-18 2015-09-23 北京泰利康信科技有限公司 Method for improving stability of platelet aggregation index
CN108169074A (en) * 2017-12-13 2018-06-15 合肥安为康医学检验有限公司 A kind of whole blood viscosity sensing equipment
WO2018113062A1 (en) * 2016-12-19 2018-06-28 宁波美康盛德生物科技有限公司 Conveying system for biochemical analyzer
CN109932284A (en) * 2019-03-15 2019-06-25 上海市嘉定区中心医院 A kind of hemorheology batch detector methods of optimization
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Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
WO1988002864A1 (en) * 1986-10-17 1988-04-21 Hemascience Laboratories, Inc. Method and apparatus for estimating hematocrit in a blood constituent processing system
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Publication number Priority date Publication date Assignee Title
CN103364577A (en) * 2012-03-29 2013-10-23 深圳市开立科技有限公司 Feeding and sampling device for hematology analyzer
CN102866083A (en) * 2012-09-29 2013-01-09 北京普利生仪器有限公司 Blood pressure measuring method
CN102866083B (en) * 2012-09-29 2014-06-18 北京普利生仪器有限公司 Blood pressure measuring method
CN104931460A (en) * 2014-03-18 2015-09-23 北京泰利康信科技有限公司 Method for improving stability of platelet aggregation index
WO2018113062A1 (en) * 2016-12-19 2018-06-28 宁波美康盛德生物科技有限公司 Conveying system for biochemical analyzer
CN108169074A (en) * 2017-12-13 2018-06-15 合肥安为康医学检验有限公司 A kind of whole blood viscosity sensing equipment
CN108169074B (en) * 2017-12-13 2020-02-11 合肥安为康医学检验有限公司 Whole blood viscosity measurement equipment
CN109932284A (en) * 2019-03-15 2019-06-25 上海市嘉定区中心医院 A kind of hemorheology batch detector methods of optimization
CN115993305A (en) * 2023-03-24 2023-04-21 常州旭普汽车零部件有限公司 Polyurethane adhesive degree testing arrangement

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