CN103149125B - Whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination method and equipment - Google Patents
Whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination method and equipment Download PDFInfo
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- CN103149125B CN103149125B CN201310039497.3A CN201310039497A CN103149125B CN 103149125 B CN103149125 B CN 103149125B CN 201310039497 A CN201310039497 A CN 201310039497A CN 103149125 B CN103149125 B CN 103149125B
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Abstract
The invention discloses a whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination method and equipment and belongs to measuring equipment and using methods. The equipment is applied to a clinical inspection department and used for detecting a hemorrheology index of a whole blood sample. The whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination equipment is characterized by comprising a hemorheology measuring device, a blood sedimentation measuring device, a puncture sampling needle translation device, a blood detection control circuit system and a horizontal centrifugal system which is independently fixed on the ground, the hemorheology measuring device, the blood sedimentation measuring device, the puncture sampling needle translation device and the blood detection control circuit system are arranged on a support of an outer shell, and the hemorheology measuring device, the blood sedimentation measuring device and the puncture sampling needle translation device are electrically connected with the blood detection control circuit system and the horizontal centrifugal system. The whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination equipment has the advantages of integrating relevant detection equipment, reducing pain of a patient due to multiple times of blooding, improving detection efficiency, achieving once blooding, and the aim at one machine completes measuring of hemorheology indexes, such as whole blood and plasma viscosity and blood sedimentation and hematocrit, and adopting a centrifugal machine independent fixed method so as to prevent a centrifugal machine from affecting other equipment.
Description
Technical field
The invention belongs to measuring equipment, be applied to clinical examination department, be used for detecting the equipment of the Hemorheology index of whole blood sample.
Background technology
Clinical examination hemorheology project, conventionally with blood flow, become the viscosity that kinetic analyzer is measured whole blood and blood plasma, but also need the manual measurement of erythrocyte sedimentation rate and packed cell volume of carrying out, and the result of complete blood rheodynamic analysis must have the viscosity number of whole blood and blood plasma, the measured value of erythrocyte sedimentation rate and hematocrit, can there is diagnostic significance, traditional esr measurement is used Wei Shi method, need to use rubber pipette bulb and erythrocyte sedimentation rate test tube that the whole blood after anti-freezing is filled in erythrocyte sedimentation rate test tube, and use encapsulant by erythrocyte sedimentation rate test tube sealed bottom in erythrocyte sedimentation rate test tube bottom, erythrocyte sedimentation rate test tube is fixed on special-purpose erythrocyte sedimentation rate test tube rack, after standing 1 hour, manually read erythrocyte sedimentation rate value, aforesaid operations is very loaded down with trivial details, and the consumptive material needing is also a lot, measure complete also needs erythrocyte sedimentation rate test tube, support cleans, to operating personnel's gimmick and technical ability, require also higher, affected work efficiency, loaded down with trivial details manual operations has also increased the infected possibility of reviewer, use in addition at present wynn's method to measure erythrocyte sedimentation rate, approximate with Wei Shi method, just erythrocyte sedimentation rate test tube can be used disposable, simplified operation, but also need manually to read the numerical value of erythrocyte sedimentation rate, also has a kind of erythrocyte sedimentation rate, hematocrit surveying instrument, that the erythrocyte sedimentation rate test tube having prepared is placed on to erythrocyte sedimentation rate, standing in hematocrit surveying instrument, erythrocyte sedimentation rate, hematocrit surveying instrument starts timing, and use the method for optoelectronic scanning in the variation of the erythrocyte sedimentation rate value of 1 hour interscan whole blood sample, after esr measurement, also need manually erythrocyte sedimentation rate test tube to be taken out and be placed on high speed centrifugation in horizontal centrifuge, after centrifugal end, test tube is placed on to erythrocyte sedimentation rate again, hematocrit surveying instrument is inner, start hematocrit process of measurement, erythrocyte sedimentation rate, hematocrit surveying instrument re-uses the numerical value of the method scanning packed cell volume of optoelectronic scanning, conventionally the manufacturer of blood flow change kinetic analyzer can provide supporting erythrocyte sedimentation rate, hematocrit surveying instrument, erythrocyte sedimentation rate, between hematocrit surveying instrument and blood flow change kinetic analyzer, use serial port data line to connect, for blood flow, become kinetic analyzer, erythrocyte sedimentation rate, hematocrit surveying instrument belongs to external accessory, at erythrocyte sedimentation rate, after hematocrit measuring instrument is measured, also need its measurement result to receive or manual making a copy of, in sum, the hand dipping of erythrocyte sedimentation rate and hematocrit or automanual erythrocyte sedimentation rate, the operation of hematocrit measuring instrument is all more loaded down with trivial details, consumptive material is used many, to reviewer's technical ability, require higher, the infected possibility of reviewer is large, the automaticity of instrument is low, the problems such as accuracy of detection is poor.
Summary of the invention
In order to overcome existing blood flow, become the deficiency that needs multiple devices in detection, the invention provides the equipment of a kind of whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit one machine mensuration.Another object of the present invention is to provide the using method of the equipment of a kind of whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit one machine mensuration.
The technical solution adopted for the present invention to solve the technical problems is: the equipment that a kind of whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit one machine are measured, it is characterized in that: the horizontal centrifugal system that is arranged on blood rheology measurement device on outer casing stand, esr measurement device puncture sampling probe translating device, blood testing control circuit system and is independently fixed on ground, consist of, each measurement mechanism and centrifugation systems are electrically connected to blood testing control circuit system.
The centrifugal electric machine support of speed governing of described horizontal centrifugal system is fixed on floor by expansion bolt, centrifugal pan rotary body is equipped with on centrifugal machine shaft top, centrifugal pan rotary body periphery is equipped with whole blood, plasma viscosity and hematocrit measures test tube (be called for short whole blood and measure test tube) support, and the reduction gearing for being connected with stepper motor is equipped with in centrifugal machine shaft bottom.
Tachogenerator and speed measuring device are equipped with in described centrifugal machine shaft bottom, and speed measuring device is electrically connected to control circuit system.
Described stepper motor is fixed on stepper motor translating device, and the stepper motor reduction gearing matching with the reduction gearing that is arranged on centrifugal machine shaft bottom is housed on step motor shaft.
Described whole blood is measured test-tube stent and is arranged on uniformly centrifugal pan rotary body periphery by rack shaft, and the measurement test tube outside of centrifugal pan rotary body one side is provided with liquid level and hematocrit scanning device, and measurement test-tube stent top is provided with whole blood and mixes vertical rod.
Described liquid level and hematocrit scanning device are arranged on outer casing stand, liquid level and hematocrit scanning device can along continuous straight runs displacements, to be used for switched scan and diverse location when centrifugal, when carrying out high speed centrifugation, liquid level and hematocrit scanning device are moved horizontally to away from centrifugation systems end, when carrying out scan operation, liquid level and hematocrit scanning device are moved horizontally near whole blood and measure test tube, and the photoelectric scanning device of liquid level and hematocrit scanning device can also be measured test tube direction along whole blood and be subjected to displacement, to be used for accurately detecting the various liquid levels that whole blood is measured test tube inside.
Described whole blood mixes vertical rod and is arranged on and is fixed on outer casing stand opertaing device, this opertaing device equipment can make whole blood mix vertical rod and do movement vertically, so that whole blood mixes when vertical rod can move downward, drives whole blood measurement test-tube stent to turn clockwise along rack shaft.
Described whole blood is measured test-tube stent upper end a boring, to be used for mounting bracket rotating shaft, boring lower end is a T-shaped test tube support, a U-shaped curved test tube that fixes is arranged at test tube support bottom, while being used for preventing high speed centrifugation, test tube comes off from support, rack shaft right side is the rocking arm of a level, when mixing operation, whole blood mixes vertical rod and moves downward and withstand rocking arm and move together, so that whole blood mixes and drives whole blood to measure test-tube stent when vertical rod can move downward to turn clockwise along rack shaft.
Whole blood, plasma viscosity and erythrocyte sedimentation rate, the using method of the equipment that hematocrit one machine is measured, it is characterized in that: A. is used the two kinds of disposable negative pressure hemostix anti-freezing of special use test tubes, whole blood wherein, what plasma viscosity and hematocrit were measured use is the disposal vacuum blood sampling test tube of liquaemin anti-freezing, blood sampling volume 3ml, esr measurement is used the disposal vacuum blood sampling test tube of sodium citrate anti-freezing, blood sampling volume 1.2ml, B. two test tubes are placed on respectively to detecting position separately, esr measurement device is understood the position, hole that record is put into simultaneously of putting into of automatic test tubes, and startup is put into the measurement timing program of test tube to each, in whole esr measurement process or measure to finish, with per family can function software, to each position, hole input of esr measurement and the catalogue number(Cat.No.) of revising appointment, with corresponding whole blood, the measurement result of blood plasma and hematocrit, C. whole blood measurement test tube is placed on whole blood measurement test-tube stent, whole blood is measured on test-tube stent rack shaft is installed, rack shaft is arranged in centrifugal pan rotary body, and whole blood measurement test-tube stent be take rack shaft as rotating shaft, can in centrifugal pan rotary body, rotate to an angle, when needs mix operation, whole blood mixes vertical rod and moves downward, whole blood is measured to test-tube stent to be rotated along rack shaft, when whole blood measurement test tube rotates to horizontality, flow in the right side that inner whole blood sample can be measured test tube to whole blood, whole blood mixes in vertical rod and carries, whole blood is measured test-tube stent and is got back to again original state, tiltedly below is mobile left again for the whole blood sample of whole blood measurement test tube inside, so repeatedly several times, the whole blood sample of whole blood measurement test tube inside is put upside down and has been mixed, D. when needs are measured whole blood viscosity, make itself and whole blood measure test tube liquid level and hematocrit sweep circuit parallel separated, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives centrifugal machine shaft and the rotation of centrifugal pan rotary body, make the sample that centrifugal pan rotary body is measured needs rotate the below to the sampling probe that punctures, centrifugal pan rotary body and centrifugal machine shaft are used spline joint to fix, and use centrifugal pan rotary body gland fastening, puncture sampling probe penetrates the seal rubber plug that whole blood is measured test tube, draw sample, puncture sampling probe is extracted test tube, puncture sampling probe translating device is moved horizontally in blood rheology measurement device, carry out the detection of whole blood viscosity, E. after the whole blood viscosity of all whole blood samples detects, start centrifugal blood plasma and carry out the mensuration of packed cell volume, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are separated from each other, the centrifugal machine shaft of electric drive on the centrifugal motor of speed governing, centrifugal pan rotary body and tachogenerator rotation, speed measuring device detects the rotating speed of centrifugal machine shaft in real time, and by speed feedback signal to control circuit system, control circuit system both can be controlled the rotating speed of the centrifugal motor of speed governing in real time, when the centrifugal motor of speed governing reaches after predetermined centrifugal rotational speed, whole blood measures test-tube stent and whole blood measurement test tube is the level of state under the effect of centrifugal force, when completing default centrifugation time, after centrifugal end, the centrifugal motor power-off of speed governing, centrifugal pan rotary body is slowly decelerated to and stops under inertia effect, whole blood measures test-tube stent and whole blood measurement test tube is got back to original state under the effect of gravity, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives the rotation of centrifugal pan rotary body, the plasma sample that centrifugal pan rotary body is measured needs rotates to the position of liquid level and hematocrit sweep circuit, the testing circuit of liquid level and hematocrit sweep circuit moves to whole blood and measures test tube both sides, blood plasma liquid level is carried out in the both sides that liquid level and hematocrit sweep circuit are measured test tube along whole blood, the detection of red blood cell liquid level, each liquid level information is passed to control circuit system simultaneously, control circuit system is according to this signal analysis, calculate the numerical value of packed cell volume, control the stroke of puncture sampling probe simultaneously, with the sampling probe that prevents from puncturing, be drawn to part-blood cell or can not enough absorption blood plasma and affect the measurement of plasma viscosity, after puncture sampling probe is drawn blood plasma, extract test tube, be moved horizontally in blood rheology measurement mechanism, carry out the detection of plasma viscosity, in measuring process, control circuit system can be to the measurement data of erythrocyte sedimentation rate and whole blood, the measurement data of plasma viscosity and hematocrit is carried out real-time preservation according to catalogue number(Cat.No.).
The invention has the beneficial effects as follows coherent detection integration of equipments is integrated, in order to prevent that hydro-extractor from having adopted hydro-extractor fixing method separately to the impact of other equipment, realized once blood sampling, a machine completes the mensuration that the blood flows such as whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit is become to index, both can alleviate the misery that patient repeatedly takes a blood sample, improve again detection efficiency.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention,
Fig. 2 is that the whole blood of the middle use of Fig. 1 is measured test-tube stent schematic diagram,
Fig. 3 is that whole blood is measured test tube and esr measurement test tube schematic diagram.
In figure, 1. whole blood is measured test tube, 2. esr measurement test tube, 3. whole blood is measured test-tube stent, 31. test tube support, 32.U type is curved, 33. rocking arms, 4. rack shaft, 5. centrifugal pan rotary body, 6. whole blood mixes vertical rod, 7. centrifugal machine shaft, 8. reduction gearing, 9. stepper motor reduction gearing, 10. stepper motor, 11. speed measuring devices, 12. tachogenerators, 13. stepper motor translating devices, the centrifugal motor of 14. speed governing, 15. puncture sampling probes, 16. liquid levels and hematocrit scanning device, the centrifugal electric machine support of 17. speed governing, 18. expansion bolts, 19. floors, 20. centrifugal pan rotary body glands, 21. outer casing stands, 22. puncture sampling probe translating devices, 23. blood rheology measurement devices, 24. esr measurement devices.
Embodiment
The specific embodiment of the present invention is, as shown in the figure:
Embodiment 1, the equipment that a kind of whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit one machine are measured, it is characterized in that: the horizontal centrifugal system that is arranged on blood rheology measurement device 23 on outer casing stand 21, esr measurement device 24 puncture sampling probe translating devices 22, blood testing control circuit system and is independently fixed on ground, consist of, each measurement mechanism and centrifugation systems are electrically connected to blood testing control circuit system.
The centrifugal electric machine support 17 of speed governing of described horizontal centrifugal system is fixed on floor 19 by expansion bolt 18, centrifugal pan rotary body 5 is equipped with on centrifugal machine shaft 7 tops, centrifugal pan rotary body periphery is equipped with whole blood measures test-tube stent 3, and the reduction gearing 8 for being connected with stepper motor 10 is equipped with in centrifugal machine shaft bottom.
Tachogenerator and speed measuring device are equipped with in described centrifugal machine shaft bottom, and speed measuring device is electrically connected to control circuit system.
Described stepper motor 10 is fixed on stepper motor translating device 13, and the stepper motor reduction gearing 9 matching with the reduction gearing that is arranged on centrifugal machine shaft bottom is housed on step motor shaft.
Described whole blood is measured test tube 1 support and is arranged on uniformly centrifugal pan rotary body 5 peripheries by rack shaft 4, and the measurement test tube outside of centrifugal pan rotary body one side is provided with liquid level and hematocrit scanning device 16, and measurement test-tube stent top is provided with whole blood and mixes vertical rod 6.
Described liquid level and hematocrit scanning device are arranged on outer casing stand 21, liquid level and hematocrit scanning device can along continuous straight runs displacements, to be used for switched scan and diverse location when centrifugal, when carrying out high speed centrifugation, liquid level and hematocrit scanning device are moved horizontally to away from centrifugation systems end, when carrying out scan operation, liquid level and hematocrit scanning device are moved horizontally near whole blood and measure test tube, and the photoelectric scanning device of liquid level and hematocrit scanning device can also be measured test tube direction along whole blood and be subjected to displacement, to be used for accurately detecting the various liquid levels that whole blood is measured test tube inside.
Described whole blood mixes vertical rod 6 and is arranged on and is fixed on outer casing stand opertaing device, this opertaing device equipment can make whole blood mix vertical rod and do movement vertically, so that whole blood mixes when vertical rod can move downward, drives whole blood measurement test-tube stent to turn clockwise along rack shaft.
Described whole blood is measured test-tube stent 3 upper ends a boring, to be used for mounting bracket rotating shaft 4, boring lower end is a T-shaped test tube support 31, test tube support bottom has one U-shaped curved 33 to fix test tube, while being used for preventing high speed centrifugation, test tube comes off from support, rack shaft right side is the rocking arm 33 of a level, when mixing operation, whole blood mixes vertical rod 6 and moves downward and withstand rocking arm and move together, so that whole blood mixes and drives whole blood to measure test-tube stent 3 when vertical rod can move downward to turn clockwise along rack shaft 4.
Embodiment 2, whole blood, plasma viscosity and erythrocyte sedimentation rate, the using method of the equipment that hematocrit one machine is measured, it is characterized in that: A. is used the two kinds of disposable negative pressure hemostix anti-freezing of special use test tubes, whole blood wherein, what plasma viscosity and hematocrit were measured use is the disposal vacuum blood sampling test tube of liquaemin anti-freezing, blood sampling volume 3ml, esr measurement is used the disposal vacuum blood sampling test tube of sodium citrate anti-freezing, blood sampling volume 1.2ml, B. two test tubes are placed on respectively to detecting position separately, esr measurement device is understood the position, hole that record is put into simultaneously of putting into of automatic test tubes, and startup is put into the measurement timing program of test tube to each, in whole esr measurement process or measure to finish, with per family can function software, to each position, hole input of esr measurement and the catalogue number(Cat.No.) of revising appointment, with corresponding whole blood, the measurement result of blood plasma and hematocrit, C. whole blood measurement test tube is placed on whole blood measurement test-tube stent, whole blood is measured on test-tube stent rack shaft is installed, rack shaft is arranged in centrifugal pan rotary body, and whole blood measurement test-tube stent be take rack shaft as rotating shaft, can in centrifugal pan rotary body, rotate to an angle, when needs mix operation, whole blood mixes vertical rod and moves downward, whole blood is measured to test-tube stent to be rotated along rack shaft, when whole blood measurement test tube rotates to horizontality, flow in the right side that inner whole blood sample can be measured test tube to whole blood, whole blood mixes in vertical rod and carries, whole blood is measured test-tube stent and is got back to again original state, tiltedly below is mobile left again for the whole blood sample of whole blood measurement test tube inside, so repeatedly several times, the whole blood sample of whole blood measurement test tube inside is put upside down and has been mixed, D. when needs are measured whole blood viscosity, make itself and whole blood measure test tube liquid level and hematocrit sweep circuit parallel separated, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives centrifugal machine shaft and the rotation of centrifugal pan rotary body, make the sample that centrifugal pan rotary body is measured needs rotate the below to the sampling probe that punctures, centrifugal pan rotary body and centrifugal machine shaft are used spline joint to fix, and use centrifugal pan rotary body gland fastening, puncture sampling probe penetrates the seal rubber plug that whole blood is measured test tube, draw sample, puncture sampling probe is extracted test tube, puncture sampling probe translating device is moved horizontally in blood rheology measurement device, carry out the detection of whole blood viscosity, E. after the whole blood viscosity of all whole blood samples detects, start centrifugal blood plasma and carry out the mensuration of packed cell volume, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are separated from each other, the centrifugal machine shaft of electric drive on the centrifugal motor of speed governing, centrifugal pan rotary body and tachogenerator rotation, speed measuring device detects the rotating speed of centrifugal machine shaft in real time, and by speed feedback signal to control circuit system, control circuit system both can be controlled the rotating speed of the centrifugal motor of speed governing in real time, when the centrifugal motor of speed governing reaches after predetermined centrifugal rotational speed, whole blood measures test-tube stent and whole blood measurement test tube is the level of state under the effect of centrifugal force, when completing default centrifugation time, after centrifugal end, the centrifugal motor power-off of speed governing, centrifugal pan rotary body is slowly decelerated to and stops under inertia effect, whole blood measures test-tube stent and whole blood measurement test tube is got back to original state under the effect of gravity, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives the rotation of centrifugal pan rotary body, the plasma sample that centrifugal pan rotary body is measured needs rotates to the position of liquid level and hematocrit sweep circuit, the testing circuit of liquid level and hematocrit sweep circuit moves to whole blood and measures test tube both sides, blood plasma liquid level is carried out in the both sides that liquid level and hematocrit sweep circuit are measured test tube along whole blood, the detection of red blood cell liquid level, each liquid level information is passed to control circuit system simultaneously, control circuit system is according to this signal analysis, calculate the numerical value of packed cell volume, control the stroke of puncture sampling probe simultaneously, with the sampling probe that prevents from puncturing, be drawn to part-blood cell or can not enough absorption blood plasma and affect the measurement of plasma viscosity, after puncture sampling probe is drawn blood plasma, extract test tube, be moved horizontally in blood rheology measurement mechanism, carry out the detection of plasma viscosity, in measuring process, control circuit system can be to the measurement data of erythrocyte sedimentation rate and whole blood, the measurement data of plasma viscosity and hematocrit is carried out real-time preservation according to catalogue number(Cat.No.).
Claims (2)
1. the equipment that a whole blood, plasma viscosity and erythrocyte sedimentation rate, hematocrit one machine are measured, it is characterized in that: by the horizontal centrifugal system that is arranged on blood rheology measurement device on outer casing stand, esr measurement device puncture sampling probe translating device, blood testing control circuit system and is independently fixed on ground, formed, each measurement mechanism and centrifugation systems are electrically connected to blood testing control circuit system
The centrifugal electric machine support of speed governing of described horizontal centrifugal system is fixed on floor by expansion bolt, centrifugal pan rotary body is equipped with on centrifugal machine shaft top, centrifugal pan rotary body periphery is equipped with whole blood measures test-tube stent, and the reduction gearing for being connected with stepper motor is equipped with in centrifugal machine shaft bottom
Tachogenerator and speed measuring device are equipped with in described centrifugal machine shaft bottom, and speed measuring device is electrically connected to control circuit system,
Described stepper motor is fixed on stepper motor translating device, and the stepper motor reduction gearing matching with the reduction gearing that is arranged on centrifugal machine shaft bottom is housed on step motor shaft,
Described whole blood is measured test-tube stent and is arranged on uniformly centrifugal pan rotary body periphery by rack shaft, and the measurement test tube outside of centrifugal pan rotary body one side is provided with liquid level and hematocrit scanning device, and measurement test-tube stent top is provided with whole blood and mixes vertical rod,
Described liquid level and hematocrit scanning device are arranged on outer casing stand, liquid level and hematocrit scanning device can along continuous straight runs displacements, to be used for switched scan and diverse location when centrifugal, when carrying out high speed centrifugation, liquid level and hematocrit scanning device are moved horizontally to away from centrifugation systems end, when carrying out scan operation, liquid level and hematocrit scanning device are moved horizontally near whole blood and measure test tube, and the photoelectric scanning device of liquid level and hematocrit scanning device can also be measured test tube direction along whole blood and be subjected to displacement, to be used for accurately detecting the various liquid levels that whole blood is measured test tube inside
Described whole blood mixes vertical rod and is arranged on and is fixed on outer casing stand opertaing device, this opertaing device equipment can make whole blood mix vertical rod and do movement vertically, so that mixing when vertical rod can move downward, whole blood drive whole blood measurement test-tube stent to turn clockwise along rack shaft
Described whole blood is measured test-tube stent upper end a boring, to be used for mounting bracket rotating shaft, boring lower end is a T-shaped test tube support, a U-shaped curved test tube that fixes is arranged at test tube support bottom, while being used for preventing high speed centrifugation, test tube comes off from support, rack shaft right side is the rocking arm of a level, can drive whole blood to measure test-tube stent and turn clockwise along rack shaft when rocking arm moves downward.
2. whole blood claimed in claim 1, plasma viscosity and erythrocyte sedimentation rate, the using method of the equipment that hematocrit one machine is measured, it is characterized in that: A. is used the two kinds of disposable negative pressure hemostix anti-freezing of special use test tubes, whole blood wherein, what plasma viscosity and hematocrit were measured use is the disposal vacuum blood sampling test tube of liquaemin anti-freezing, blood sampling volume 3ml, esr measurement is used the disposal vacuum blood sampling test tube of sodium citrate anti-freezing, blood sampling volume 1.2ml, B. two test tubes are placed on respectively to detecting position separately, esr measurement device is understood the position, hole that record is put into simultaneously of putting into of automatic test tubes, and startup is put into the measurement timing program of test tube to each, in whole esr measurement process or measure to finish, with per family can function software, to each position, hole input of esr measurement and the catalogue number(Cat.No.) of revising appointment, with corresponding whole blood, the measurement result of blood plasma and hematocrit, C. whole blood measurement test tube is placed on whole blood measurement test-tube stent, whole blood is measured on test-tube stent rack shaft is installed, rack shaft is arranged in centrifugal pan rotary body, and whole blood measurement test-tube stent be take rack shaft as rotating shaft, can in centrifugal pan rotary body, rotate to an angle, when needs mix operation, whole blood mixes vertical rod and moves downward, whole blood is measured to test-tube stent to be rotated along rack shaft, when whole blood measurement test tube rotates to horizontality, flow in the right side that inner whole blood sample can be measured test tube to whole blood, whole blood mixes in vertical rod and carries, whole blood is measured test-tube stent and is got back to again original state, tiltedly below is mobile left again for the whole blood sample of whole blood measurement test tube inside, so repeatedly several times, the whole blood sample of whole blood measurement test tube inside is put upside down and has been mixed, D. when needs are measured whole blood viscosity, make itself and whole blood measure test tube liquid level and hematocrit sweep circuit parallel separated, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives centrifugal machine shaft and the rotation of centrifugal pan rotary body, make the sample that centrifugal pan rotary body is measured needs rotate the below to the sampling probe that punctures, centrifugal pan rotary body and centrifugal machine shaft are used spline joint to fix, and use centrifugal pan rotary body gland fastening, puncture sampling probe penetrates the seal rubber plug that whole blood is measured test tube, draw sample, puncture sampling probe is extracted test tube, puncture sampling probe translating device is moved horizontally in blood rheology measurement device, carry out the detection of whole blood viscosity, E. after the whole blood viscosity of all whole blood samples detects, start centrifugal blood plasma and carry out the mensuration of packed cell volume, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are separated from each other, the centrifugal machine shaft of electric drive on the centrifugal motor of speed governing, centrifugal pan rotary body and tachogenerator rotation, speed measuring device detects the rotating speed of centrifugal machine shaft in real time, and by speed feedback signal to control circuit system, control circuit system both can be controlled the rotating speed of the centrifugal motor of speed governing in real time, when the centrifugal motor of speed governing reaches after predetermined centrifugal rotational speed, whole blood measures test-tube stent and whole blood measurement test tube is the level of state under the effect of centrifugal force, when completing default centrifugation time, after centrifugal end, the centrifugal motor power-off of speed governing, centrifugal pan rotary body is slowly decelerated to and stops under inertia effect, whole blood measures test-tube stent and whole blood measurement test tube is got back to original state under the effect of gravity, stepper motor translating device Driving Stepping Motor and stepper motor reduction gearing and reduction gearing are intermeshing, stepper motor rotarily drives the rotation of centrifugal pan rotary body, the plasma sample that centrifugal pan rotary body is measured needs rotates to the position of liquid level and hematocrit sweep circuit, the testing circuit of liquid level and hematocrit sweep circuit moves to whole blood and measures test tube both sides, blood plasma liquid level is carried out in the both sides that liquid level and hematocrit sweep circuit are measured test tube along whole blood, the detection of red blood cell liquid level, each liquid level information is passed to control circuit system simultaneously, control circuit system is according to this signal analysis, calculate the numerical value of packed cell volume, control the stroke of puncture sampling probe simultaneously, with the sampling probe that prevents from puncturing, be drawn to part-blood cell or can not enough absorption blood plasma and affect the measurement of plasma viscosity, after puncture sampling probe is drawn blood plasma, extract test tube, be moved horizontally in blood rheology measurement mechanism, carry out the detection of plasma viscosity, in measuring process, control circuit system can be to the measurement data of erythrocyte sedimentation rate and whole blood, the measurement data of plasma viscosity and hematocrit is carried out real-time preservation according to catalogue number(Cat.No.).
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| CN201310039497.3A CN103149125B (en) | 2013-02-01 | 2013-02-01 | Whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination method and equipment |
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|---|---|---|---|
| CN201310039497.3A CN103149125B (en) | 2013-02-01 | 2013-02-01 | Whole blood and plasma viscosity and blood sedimentation and hematocrit one-machine determination method and equipment |
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| CN103149125A CN103149125A (en) | 2013-06-12 |
| CN103149125B true CN103149125B (en) | 2014-10-29 |
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| CN104713805A (en) * | 2015-03-26 | 2015-06-17 | 山东美医林电子仪器有限公司 | Device for detecting blood rheology and detection method based on device |
| CN104698199A (en) * | 2015-04-01 | 2015-06-10 | 山东美医林电子仪器有限公司 | Hemorheology detecting device |
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| CN109946337B (en) * | 2017-12-21 | 2022-01-04 | 王玉麟 | Blood detection method |
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| CN112284850B (en) * | 2020-10-22 | 2021-05-18 | 四川大学华西医院 | Intelligent analysis front-end processing equipment after gastroenterology biopsy |
| CN113219186B (en) * | 2021-01-29 | 2024-02-09 | 武汉市农业科学院 | Full-automatic heavy metal analyzer |
| CN113252562B (en) * | 2021-05-24 | 2022-10-21 | 南京仁迈生物科技有限公司 | Erythrocyte volume detection device for chemiluminescence apparatus |
| WO2023140755A1 (en) * | 2022-01-21 | 2023-07-27 | Efremov Vitalii | Point-of-care device for erythrocyte sedimentation monitoring |
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| CN2081535U (en) * | 1990-12-28 | 1991-07-24 | 天津中医学院 | Infrared multi-shearing viscosity-determining instrument |
| CN102236009A (en) * | 2010-04-28 | 2011-11-09 | 上海安彩智能技术有限公司 | Integrated blood inspection platform and using method thereof |
| CN102486446A (en) * | 2010-12-01 | 2012-06-06 | 上海安彩智能技术有限公司 | Automatic blood rheometer |
| CN102854094B (en) * | 2012-10-10 | 2014-09-10 | 重庆大学 | Multichannel microfluidic blood rheological analysis chip as well as analysis system and analysis method of chip |
| CN203037549U (en) * | 2013-02-01 | 2013-07-03 | 山东美医林电子仪器有限公司 | One-machine determination equipment of whole blood and plasma viscosity and blood sedimentation and hematocrit |
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