CN110398596A - Full-automatic sample introduction blood cell analysis measurement method and device carry out the method for mixing operation to peripheral blood test tube - Google Patents
Full-automatic sample introduction blood cell analysis measurement method and device carry out the method for mixing operation to peripheral blood test tube Download PDFInfo
- Publication number
- CN110398596A CN110398596A CN201910324839.3A CN201910324839A CN110398596A CN 110398596 A CN110398596 A CN 110398596A CN 201910324839 A CN201910324839 A CN 201910324839A CN 110398596 A CN110398596 A CN 110398596A
- Authority
- CN
- China
- Prior art keywords
- test tube
- peripheral blood
- sample
- blood
- rack
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009534 blood test Methods 0.000 title claims abstract description 178
- 210000005259 peripheral blood Anatomy 0.000 title claims abstract description 152
- 239000011886 peripheral blood Substances 0.000 title claims abstract description 149
- 238000002156 mixing Methods 0.000 title claims abstract description 142
- 238000004458 analytical method Methods 0.000 title claims abstract description 70
- 210000000601 blood cell Anatomy 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims abstract description 26
- 238000000691 measurement method Methods 0.000 title claims abstract description 20
- 238000012360 testing method Methods 0.000 claims abstract description 357
- 210000004369 blood Anatomy 0.000 claims abstract description 76
- 239000008280 blood Substances 0.000 claims abstract description 76
- 238000005070 sampling Methods 0.000 claims abstract description 36
- 238000005259 measurement Methods 0.000 claims abstract description 25
- 238000010521 absorption reaction Methods 0.000 claims abstract description 9
- 230000009471 action Effects 0.000 claims abstract description 6
- 230000007246 mechanism Effects 0.000 claims description 85
- 238000001514 detection method Methods 0.000 claims description 39
- 210000000078 claw Anatomy 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 10
- 230000007423 decrease Effects 0.000 claims description 8
- 238000004159 blood analysis Methods 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 5
- 230000002093 peripheral effect Effects 0.000 claims description 5
- 230000000630 rising effect Effects 0.000 claims description 5
- 238000007689 inspection Methods 0.000 claims description 2
- 238000010586 diagram Methods 0.000 description 7
- 238000010790 dilution Methods 0.000 description 6
- 239000012895 dilution Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 3
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 description 3
- 230000000149 penetrating effect Effects 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000002473 artificial blood Substances 0.000 description 1
- 210000000746 body region Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000012812 general test Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1051—General features of the devices using the transfer device for another function for transporting containers, e.g. retained by friction
Abstract
The invention discloses a kind of full-automatic sample introduction blood cell analysis measurement method and devices, which comprises during sample introduction loading platform traverse feed rack for test tube, determines the loading condition of the test tube on rack for test tube；In the case where being mounted with test tube on determining rack for test tube, test tube type is determined, wherein test tube type includes venous blood test tube and peripheral blood test tube；Blending manner is determined according to test tube type, and mixing operation is carried out to invisible spectro blood using determining blending manner；When rack for test tube, which is fed into, inhales sample position, falling head is determined according to determining test tube type, sampling needle executes lowering action corresponding with the falling head determined and draws sample；Analysis measurement carried out to the sample of absorption, after analysis is measured, rack for test tube, which is fed to the unloading of unloading position and is withdrawn into, to be unloaded on carrying platform, exports the analysis measurement result of the sample of absorption.Described device is for realizing the method.It is high degree of automation of the present invention, high-efficient, reduce clinical staff labor intensity.
Description
Technical field
The invention belongs to blood cell analysis technical fields, it is more particularly related to which a kind of full-automatic sample introduction blood is thin
Born of the same parents' analysis measurement method and device carry out the method for mixing operation to peripheral blood test tube.
Background technique
Full-automatic sample introduction blood cell analysis measuring device is only applicable to venous blood at present, but for peripheral blood, since it is adopted
Blood volume is fewer, does not there is corresponding full-automatic sample introduction blood cell analysis measuring device at present.Because of existing blood cell analysis
The venous blood evenly mixing device of existing setting in instrument be not suitable for peripheral blood mixing, so at the beginning when, need operator
It is mixed manually, then a hand-held test tube equipped with the peripheral blood blood sample mixed is placed on to the sampling of cellanalyzer
Under needle, the peripheral blood blood sample mixed is sucked in cellanalyzer and is tested and analyzed by sampling needle, haemocyte in this case
It, can only be by way of hand sampling when analyzer analyzes peripheral blood.And the efficiency of hand sampling mode is too low, therefore on the market
Occur realizing the device of automatic sampling to a certain extent, when in use, test tube is placed on rack for test tube the device, blood cell analysis
Instrument can be automatically brought into operation the test tube on entire rack for test tube, and operator is only placed on rack for test tube with by test tube, without lifting
Under test tube to sampling needle；But cellanalyzer is needed first to squeeze into dilution in test tube, then operator is also by test tube
Frame takes out inside cellanalyzer, adds peripheral blood blood sample again in the test tube for beaten dilution, it is thin then to put back to blood again
Inside born of the same parents' analyzer, compressing mixing is carried out by cellanalyzer, then carries out subsequent detection operation automatically.The certain journey of the device
Automatic sampling is had been realized on degree, but manual operation is still wanted in centre, i.e., has beaten in test tube in cellanalyzer dilute
After releasing liquid, operator is needed to take out test tube, then the artificial blood sample for adding peripheral blood toward test tube the inside.And it can not automatic distinguishing
Venous blood and peripheral blood, automatic sampling efficiency are still to be improved.
Summary of the invention
The purpose of the present invention is to provide a kind of full-automatic sample introduction blood cell analysis measurement method and devices, being capable of automatic area
Other venous blood and peripheral blood, and automatic sampling detection is carried out to venous blood and peripheral blood.
Purpose to realize the present invention, the embodiment of the present invention provide a kind of pair of peripheral blood test tube and carry out the method for mixing operation,
It is characterised by comprising:
Control test tube clamp claw clip holds the rising of peripheral blood test tube；
Control peripheral blood test tube mixing mechanism, which is fed into, mixes position, and the test tube clamp claw clip holds the decline of peripheral blood test tube,
Peripheral blood test tube is placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, peripheral blood test tube bottom and peripheral blood test tube are mixed
The test tube support of even mechanism abuts, and test tube clamping jaw executes horizontal feed and moves to horizontal ready bit far from rack for test tube direction；
The brushless motor of peripheral blood test tube mixing mechanism drives eccentric block rotation, and then perforation test tube support is driven to generate revolution
Formula is swung, and is caused to set the blood sample in the peripheral vessel abutted with the test tube support and is mixed.
Purpose to realize the present invention, the embodiment of the present invention provide a kind of full-automatic sample introduction blood cell analysis measurement method, institute
The method of stating includes the following steps:
During sample introduction loading platform traverse feed rack for test tube, the loading condition of the test tube on rack for test tube is determined；
In the case where being mounted with test tube on determining the rack for test tube, the test tube of the test tube loaded in the rack for test tube is determined
Type, wherein the test tube type includes venous blood test tube and peripheral blood test tube；
Corresponding blending manner is determined according to the test tube type, and using determining blending manner to invisible spectro blood
Carry out mixing operation；
When rack for test tube, which is fed into, inhales sample position, falling head is determined according to the test tube type of the determination, sampling needle executes
Lowering action corresponding with the falling head of the determination simultaneously draws sample；
Analysis measurement is carried out to the sample of absorption, after analysis is measured, rack for test tube is fed to the unloading of unloading position and is withdrawn into
It unloads on carrying platform, exports the analysis measurement result of the sample of absorption.
Optionally, in one embodiment, the tube bottom thickness of the peripheral blood test tube is greater than the pipe of the venous blood test tube
Base thickness degree, the tube bottom of the peripheral blood test tube are light-permeable.
Optionally, in one embodiment, the peripheral blood test tube includes outer tube body and interior tube body, the pipe of said inner tube body
Body bottom is located at the central region of outer tube body, and the lower area of outer tube body is light-permeable.
Optionally, in one embodiment, described that corresponding blending manner is determined according to the test tube type, and using true
Fixed blending manner carries out mixing operation to invisible spectro blood, further includes:
In the case where the test tube type is peripheral blood test tube, using peripheral blood test tube mixing mechanism in the test tube
Blood sample carry out mixing operation.
Optionally, in one embodiment, it is described using peripheral blood test tube mixing mechanism to the invisible spectro blood sample into
Row mixes operation, further includes:
The test tube is placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, the bottom and end of the test tube are made
The test tube support of tip blood test tube evenly mixing device abuts.
Optionally, in one embodiment, the perforation that the test tube is placed on peripheral blood test tube mixing mechanism tries
Guan Cangzhong, after abutting the bottom of the test tube with the test tube support of peripheral blood test tube mixing mechanism, further includes:
The bottom of the test tube and the peripheral blood test tube mixing mechanism be that conduit saddle abuts in the case where, the tip
The brushless motor of blood test tube evenly mixing device drives eccentric block rotation, and then the test tube support for driving the test tube to be abutted generates shake
It is dynamic, cause the rotary swing of peripheral blood test tube and vibration penetrated through in test tube storehouse, to realize the mixing of blood sample in test tube.
Optionally, in one embodiment, described that corresponding blending manner is determined according to the test tube type, and using true
Fixed blending manner carries out mixing operation to invisible spectro blood, further includes:
In the case where the test tube type is venous blood test tube, test tube clamping jaw clamps test tube and is moved to from rack for test tube
Above rack for test tube, implementation overturns mix to blood sample back and forth.
Optionally, in one embodiment, in the case where the test tube type is venous blood test tube, it is determining with it is described quiet
The corresponding rotary speed parameter of arteries and veins blood test tube, the brushless motor of the peripheral blood test tube mixing mechanism use the rotary speed parameter of the determination
Mixing operation is carried out to the invisible spectro blood sample.
In addition, the embodiment of the present invention also provides a kind of full-automatic sample introduction blood cell analysis measuring device, including control unit,
Described device further includes connecting with described control unit and controlling its execution by sending control instruction by described control unit
Platform machine is exited in the device for analyzing samples of corresponding operating, venous blood test tube mixing mechanism, peripheral blood test tube mixing mechanism, unloading
Structure, sampling needle, sample introduction loading platform, test tube detection unit, test tube clamping jaw；
Rack for test tube for holding test tubes frame and is fed to sample analysis mechanism by the sample introduction loading platform, so that the sample
This analysis institution carries out sample analysis measurement to the invisible spectro blood sample on rack for test tube；
The test tube detection unit is used to detect the loading condition and test tube type of test tube on the rack for test tube；
The sampling needle is used to execute decline corresponding with the falling head according to the falling head that control unit determines dynamic
Make and draws sample so that the device for analyzing samples carries out sample analysis measurement；
The venous blood test tube mixing mechanism and/or peripheral blood test tube mixing mechanism are used for the test tube on the rack for test tube
Interior blood sample carries out mixing operation；
It is described unloading exit platform mechanism for unload exit rack for test tube；
The test tube clamping jaw is for clamping the rising of peripheral blood test tube；
The peripheral blood test tube mixing mechanism mixes position for controlled be fed into, and the test tube clamp claw clip holds peripheral blood examination
Pipe decline, the test tube clamping jaw is for peripheral blood test tube to be placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, tip
Blood test tube bottom is abutted with the test tube support of peripheral blood test tube mixing mechanism, and test tube clamping jaw executes horizontal feed far from rack for test tube direction
Move to horizontal ready bit；
Peripheral blood test tube mixing mechanism includes brushless motor and eccentric block, and brushless motor drives eccentric block rotation, and then band
Dynamic perforation test tube support generates rotary swing, causes to set the blood sample in the peripheral vessel abutted with the test tube support and is mixed.
Optionally, in one embodiment, the test tube detection unit is that can be set and fill in the sample introduction to optocoupler is penetrated
On any operative position before mixing position or mixing position on carrying platform.
Optionally, in one embodiment, test tube pawl, the test tube pawl are provided on the venous blood test tube mixing mechanism
Blood sample is mixed for implementing to overturn back and forth from clamping test tube in rack for test tube and being moved to above rack for test tube.
Optionally, in one embodiment, the peripheral blood test tube mixing mechanism includes feed mechanism, at least three levels
Bracket, flexible column, perforation test tube storehouse, the test tube support with inner sunken face, brushless motor and eccentric block
Optionally, in one embodiment, the brushless motor is located on the second horizontal bracket, and the test tube support is located at the
On two horizontal brackets, the perforation test tube position in storehouse is on third horizontal bracket.
Optionally, in one embodiment, one end of the flexible column connects the first level bracket, other end connection
Second horizontal bracket.
The method and device for implementing the embodiment of the present invention has the following beneficial effects:
The present invention provides a kind of full-automatic sample introduction blood cell analysis measurement method and devices, realize more easy end
Tip blood whole blood test operation mode, first is that being not necessarily to pre-dilution outside the machine of dilution, second is that measurement sample without stringent quantitative requirement
It influences, need to only meet minimum test dosage requirement, such as the measurement method of venous blood, what is provided through the invention is full-automatic
It is automatic on same machine that peripheral blood sample and venous blood sample may be implemented in sample introduction blood cell analysis measurement method and device
Sample introduction completes detection, does not need to detect on different correspondence cellanalyzers respectively, simplifies the operation of medical staff, drops
The cost of Di Liao hospital detection.Present invention method and device can pass through detection unit automatic identification venous samples simultaneously
Product acquire the test tube type of test tube and tip blood sample acquisition test tube, and implement corresponding blood blending manner according to test tube, and
It is sampled analysis automatically according to different test tube type control sampling needles, finally output analysis measurement result.The present invention is implemented
Example provide method and device high degree of automation, release the labor intensity of clinical staff, improve blood sample sample introduction and
The efficiency of detection.
To enable the above objects, features and advantages of the present invention to be clearer and more comprehensible, better embodiment is cited below particularly, and match
Appended attached drawing is closed, is described in detail below.
Detailed description of the invention
It, below will be to use required in embodiment in order to illustrate more clearly of the technical solution of embodiment of the present invention
Attached drawing be briefly described, it should be understood that the following drawings illustrates only certain embodiments of the invention, therefore should not be seen
Work is the restriction to range, for those of ordinary skill in the art, without creative efforts, can be with
Other relevant attached drawings are obtained according to these attached drawings.
Fig. 1 is a kind of structural schematic diagram of full-automatic sample introduction blood cell analysis measuring device in one embodiment；
Fig. 2 is the full-automatic sample introduction blood cell analysis measuring device stereoscopic schematic diagram of the embodiment of the present invention；
Fig. 3 is a kind of flow diagram of full-automatic sample introduction blood cell analysis measurement method in one embodiment；
Fig. 4 is peripheral blood cuvette construction form figure of the embodiment of the present invention；
Fig. 5 is that the embodiment of the present invention loads the rack for test tube structure after venous blood test tube and/or peripheral blood test tube and effect is shown
It is intended to；
Fig. 6 is that the embodiment of the present invention loads the rack for test tube structure after venous blood test tube and/or peripheral blood test tube and effect is shown
It is intended to；
Fig. 7 is apparatus structure partial schematic diagram of the sampling needle of the embodiment of the present invention in automatic sample bits；
Fig. 8 is peripheral blood test tube mixing mechanism structural schematic diagram of the embodiment of the present invention；
Fig. 9 is the flow diagram for mix to test tube operation in the embodiment of the present invention；
Figure 10 is test tube of embodiment of the present invention clamping jaw and peripheral blood test tube mixing mechanism in a certain interoperation position state
Schematic diagram.
Specific embodiment
Below in conjunction with attached drawing in embodiment of the present invention, to the technical solution in embodiment of the present invention carry out it is clear,
It is fully described by, it is clear that described embodiment is only some embodiments of the invention, rather than whole embodiment party
Formula.The component of the embodiment of the present invention being usually described and illustrated herein in the accompanying drawings can be arranged with a variety of different configurations
And design.Therefore, requirement is not intended to limit to the detailed description of the embodiments of the present invention provided in the accompanying drawings below to protect
The scope of the present invention of shield, but it is merely representative of selected embodiment of the invention.Based on embodiments of the present invention, this field
Technical staff's every other embodiment obtained without making creative work, belongs to protection of the present invention
Range.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", " vertical ",
The orientation or positional relationship of the instructions such as "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of retouching
It states the present invention and simplifies description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific
Orientation construction and operation, therefore be not considered as limiting the invention.In addition, term " first ", " second ", " third " are only
For descriptive purposes, it is not understood to indicate or imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " installation ", " phase
Even ", " connection " shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected；It can
To be mechanical connection, it is also possible to be electrically connected；It can be directly connected, can also can be indirectly connected through an intermediary
Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood at this with concrete condition
Concrete meaning in invention.
In the present embodiment, a kind of full-automatic sample introduction blood cell analysis measurement method and device are proposed, it being capable of automatic area
Other venous blood and peripheral blood, and automatic sampling detection is carried out to venous blood and peripheral blood.
Specifically, in one embodiment, as shown in Figure 1, proposing a kind of full-automatic sample introduction blood cell analysis measurement dress
It sets, including control unit 100, described device further includes connecting with described control unit 100 and passing through hair by described control unit
Control instruction is sent to control its device for analyzing samples 1001, venous blood test tube mixing mechanism 200, peripheral blood for executing corresponding operating
Platform mechanism 2, sampling needle 7, sample introduction loading platform 6, test tube detection unit 1002 are exited in test tube mixing mechanism 300, unloading；
Wherein,
Rack for test tube for holding test tubes frame and is fed to device for analyzing samples by the sample introduction loading platform, so that the sample
This analytical equipment carries out sample analysis measurement to the invisible spectro blood sample on rack for test tube；
The test tube detection unit is used to detect the loading condition and test tube type of test tube on the rack for test tube；
The sampling needle is used to execute decline corresponding with the falling head according to the falling head that control unit determines dynamic
Make and draws sample so that the device for analyzing samples carries out sample analysis measurement；
The venous blood test tube mixing mechanism and/or peripheral blood test tube mixing mechanism are used for the test tube on the rack for test tube
Interior blood sample carries out mixing operation；
It is described unloading exit platform mechanism for unload exit rack for test tube.
Specifically, loading condition of the above-mentioned test tube detection unit for test tube in test tubes frame, and detect the examination of loading
Manage corresponding test tube type.The detection of test tube detection unit judges blood sample tubes type in rack for test tube, i.e. blood in rack for test tube
Sample tube is venous blood test tube or peripheral blood test tube, and according to the testing result of test tube detection unit, described control unit is to examination
It identifies that the test tube of different test tube types is corresponding on pipe support and executes the mixing of venous blood test tube mixing mechanism or the mixing of peripheral blood test tube
Mechanism mixes, and for venous blood test tube and two kinds of peripheral blood test tube different test tube types, control unit controls sampling needle decline not
Blood sample in test tube is drawn, with depth so that the sample analyser carries out sample analysis measurement.
For example, the full-automatic sample introduction blood cell analysis measuring device can be based on entity apparatus as shown in Figure 2.
The embodiment of the present invention also provides a kind of full-automatic sample introduction blood cell analysis measurement method, as shown in figure 3, the method
Include the following steps:
Step S1: during sample introduction loading platform traverse feed rack for test tube, the loading feelings of the test tube on rack for test tube are determined
Condition.
Whether be mounted with test tube in test tubes frame by test tube detection unit, also, the execution of the step be into
What sample loading platform carried out in the case where laterally feeding rack for test tube.That is, the execution of subsequent step is only in test tube
It is just executed in the case where being mounted with test tube on frame, to avoid the waste of unnecessary program.
In a specific embodiment, test tube detection unit is that a pair penetrates optocoupler, passes through examination in rack for test tube traverse feed
Pipe whether there is or not detection to optocoupler is penetrated in the case where, if the test tube whether there is or not detection to penetrate optocoupler generation block signal, judge rack for test tube
In with the presence of test tube, it is on the contrary, it is determined that not to be mounted with test tube in rack for test tube.
Step S2: in the case where being mounted with test tube on determining the rack for test tube, the examination loaded in the rack for test tube is determined
The test tube type of pipe, wherein the test tube type includes venous blood test tube and peripheral blood test tube.
In the case where being mounted with test tube on rack for test tube, need to analyze the invisible spectro blood sample of loading.In
In the present embodiment, there are two types of the test tube possibility of rack for test tube, one is common venous blood test tube, a kind of special peripheral blood examination
Pipe, different test tubes have corresponded to subsequent different operating procedure.Therefore, it is necessary to differentiate to test tube type.Specifically, passing through
Test tube detection unit carrys out the test tube type of the test tube loaded in test tubes frame, wherein test tube type includes venous blood test tube
And peripheral blood test tube.
In an alternative embodiment, the tube bottom thickness of peripheral blood test tube is greater than the tube bottom thickness of the venous blood test tube
Degree, wherein the tube bottom of test tube with a thickness of outside test tube bottom and test tube intracavity bottom (bottommost that test tube inner cavity can fill blood sample)
Between spacing distance size.For example, the test tube intracavity bottom of peripheral blood test tube is located in the middle part of test tube, tube bottom is with a thickness of test tube
The half of whole height, and the tube bottom of venous blood test tube is with a thickness of can for general test tube wall thickness, with test tube whole height
It ignores.In general, the material of test tube is glass or PP material, that is to say, that part corresponding to tube bottom thickness is
Light-permeable, also, no matter in test tube it is intracavitary whether have equipped with blood sample in the case where, be light-permeable.
In the case where being equipped with blood sample, the lower area of test tube corresponding to the tube bottom thickness of the peripheral blood test tube is can
Light transmission, for the venous blood test tube because tube bottom thickness is smaller, tube bottom light-permeable region is negligible, therefore, is being equipped with
In the case where blood sample, the lower area of test tube can not light transmission, that is to say, that test tube detection unit can pass through detection examination
Pipe lower area whether the feature of light-permeable is determined as any test tube.
In another alternative embodiment, as shown in figure 4, the peripheral blood test tube includes outer tube body and interior tube body, institute
The bottom for stating interior tube body is located at the central region of outer tube body, and the lower area of outer tube body is light-permeable.
As shown in figure 4, peripheral blood test tube includes tube body 11 and pipe cap 12；12 entirety of pipe cap or middle part are rubber material, with
Just sampling needle penetrates through；Tube body 11 includes interior tube body and outer tube body, and the bottom of said inner tube body is set as taper round bottom, with
Just sampling needle submerges the depth in blood sample；The outer tube body is interior tube body bottom taper top straight flange along the tube body short transverse
The skirt 111 for extending downwardly certain length composition, so that peripheral blood collecting tube is put into the clamping that rack for test tube is suitable for test tube clamping jaw
Be put into, without changing rack for test tube；Skirt 111 is transparent or semitransparent state close to bottom zone, is examined to the vacuum blood collection tube
It surveys light and does not generate occlusion state.Specifically can be as shown in Figure 5 and Figure 6, Fig. 5 and Fig. 6 give and are mounted with venous blood on rack for test tube
The case where test tube and peripheral blood test tube, wherein as shown in figure 5, the corresponding blood sample in venous blood test tube of number 011,
The corresponding blood sample in peripheral blood test tube of number 021, as shown in fig. 6, it is corresponding to be mounted with number 010 on rack for test tube 5
Be venous blood test tube and number 020 it is corresponding be peripheral blood test tube.
In another alternative embodiment, test tube detection unit is photoelectric sensor, such as be can be to optocoupler is penetrated, and is led to
It crosses to penetrating optocoupler to determine detection, and the photoelectric information received according to the optocoupler of opposite side to the bottom of test tube or lower area
To determine test tube type.In the present embodiment, it is flat in sample introduction loading to determine that the test tube detection unit of test tube type can be setting
On any operative position before mixing position or mixing position on platform, that is to say, that test tube type before carrying out mixing operation
It is detected.
Optionally, whether the test tube detection unit is selected to optocoupler is penetrated, as shown in Figure 7, wherein fill on test tubes frame
The the first test tube detection unit for being loaded with test tube is to be set on the venous blood test tube mixing mechanism, test tubes to optocoupler 8 is penetrated
Second test tube detection unit of type is to be set on the peripheral blood test tube mixing mechanism to optocoupler 10 is penetrated.
That is, test tube detection unit is when rack for test tube traverse feed is to preset working position, if test tube detection pair
It penetrates optocoupler not to be blocked, is judged as micro peripheral blood test tube；If test tube detection is blocked to penetrating optocoupler, it is judged as that venous blood tries
Pipe.Specifically, present invention method by it is newly-increased be arranged in test tube bottom blood sample region to penetrate optocoupler low and high level,
And binding tube has been detected as test tube state whether there is or not judgement and has realized the two kinds of test tube type inspections of venous blood test tube and peripheral blood test tube
It surveys；It is transparent or semitransparent state that the peripheral blood test tube, which corresponds to described increase newly to the tube body region for penetrating optocoupler,.
Step S3: corresponding blending manner is determined according to the test tube type, and using determining blending manner to test tube
Interior blood carries out mixing operation.
In the present embodiment, the corresponding different blending manner of venous blood test tube and peripheral blood test tube, blood sample therein
Amount and position are different, it is thus necessary to determine that blending manner corresponding with test tube type mixes invisible spectro blood
Even operation, to improve the effective percentage and accuracy rate of subsequent suction sample and analysis measurement.
Specifically, in the case where test tube type is venous blood test tube, using general corresponding with venous blood test tube mixed
Even operation carries out mixing operation.For example, test tube clamping jaw 9 is implemented to come from clamping test tube in rack for test tube and being moved to above rack for test tube
It returns to overturn and blood sample is mixed.
In the case where test tube type is peripheral blood test tube, need to carry out using mixing corresponding with peripheral blood type operation
Mix operation.Specifically, carrying out mixing operation to the invisible spectro blood sample using peripheral blood test tube mixing mechanism.Peripheral blood examination
Pipe mixing mechanism is internally provided with perforation test tube storehouse, test tube support, brushless motor, eccentric block, during carrying out mixing operation,
The test tube is placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism by control, makes bottom and the peripheral blood of the test tube
The test tube support of test tube evenly mixing device abuts, so that the effect of the mixing operation in later period is best.Bottom and institute in the test tube
State peripheral blood test tube mixing mechanism is in the case that conduit saddle abuts, and the brushless motor of the peripheral blood test tube evenly mixing device drives
Eccentric block rotation, and then the test tube support for driving the test tube to be abutted generates vibration, causes the peripheral blood penetrated through in test tube storehouse examination
Rotary swing and vibration are managed, to realize the mixing of blood sample in test tube.
In another alternative embodiment, in order to save the space of equipment, venous blood test tube will can be mixed
The mixing mechanism that operation and peripheral blood mix operation is set as the same mechanism, for example, being that peripheral blood test tube mixes
Mechanism.Specifically, in the present embodiment, in the case where the test tube type is venous blood test tube, the determining and venous blood
The corresponding rotary speed parameter of test tube, the brushless motor of the peripheral blood test tube mixing mechanism is using the rotary speed parameter of the determination to institute
It states invisible spectro blood sample and carries out mixing operation.That is, peripheral blood test tube and the corresponding different mixing of venous blood test tube
Parameter carries out mixing behaviour using different mixing parameters (such as rotary speed parameter of brushless motor) for different test tube types
Make.
It is peripheral blood test tube shown in number 300 as shown in figure 8, being venous blood test tube mixing mechanism shown in number 200
Mixing mechanism is to contain the sample of sampling needle 7 to draw sampling needle mechanism shown in number 400.
Step S4: when rack for test tube, which is fed into, inhales sample position, determining falling head according to the test tube type of the determination, samples
Needle executes lowering action corresponding with the falling head of the determination and draws sample.
As mentioned previously, because the difference (tube bottom height) of test tube type and the difference of invisible spectro blood volume, lead to difference
Test tube type in blood sample height it is also different, therefore, which results in sampling needles to be also required to use when drawing sample
Different height is drawn under partial picture less than sample or the sample of absorption if using identical height and may result in
It is insufficient.Therefore, in the present embodiment, in the case where rack for test tube is fed into and inhales sample position, it is necessary to be determined according to test tube type
Then sampling needle corresponding position during drawing sample, i.e., corresponding falling head control sampling needle and execute and determine
The corresponding lowering action of falling head, then carry out draw sample operation, thus improve draw sample success rate, mention
The validity of high subsequent samples analysis.
Step S5: carrying out analysis measurement to the sample of absorption, and after analysis is measured, rack for test tube is fed to the unloading of unloading position
It is withdrawn into and unloads on carrying platform, export the analysis measurement result of the sample of absorption.
In this step, sample analysis mechanism carries out analysis measurement to the sample that sampling needle is drawn, and is measured in analysis
Export corresponding analysis measurement result later for using；Also, after analysis is measured, the test tube on rack for test tube is no longer
It is operated, needs to unload in test tube thereon in this case, that is to say, that control rack for test tube, which is fed into, to be unloaded
Carry position with exit to unload carrying platform complete this automatic sampling and analysis measurement process.
In the embodiment of the present invention, specifically, after identifying test tube state and type, such as identify that peripheral blood tries
Guan Shi, test tube clamping jaw is first carried out and is closed to the horizontal feed in test tube direction from its ready position on venous blood test tube mixing mechanism
Right position is set, and generates clamping to peripheral blood test tube；Then moved axially upward to proper height along test tube, it is ensured that lift test tube and detach
Rack for test tube and be raised test tube bottom between test tube top of support space allow peripheral blood test tube mixing mechanism horizontal feed be inserted into.
That is, be provided with test tube pawl on venous blood test tube mixing mechanism, the test tube pawl for the test tube on holding test tubes frame with
Mobile test tube.It is quiet after identifying test tube state and type, such as when identifying peripheral blood test tube in the embodiment of the present invention
Test tube clamping jaw 9 first carries out the horizontal feed suitable position to test tube direction from its ready position on arteries and veins blood test tube mixing mechanism,
Clamping is generated to peripheral blood test tube；Then moved axially upward to proper height along test tube, it is ensured that lift test tube and detach rack for test tube 5
And be raised test tube bottom allows peripheral blood test tube mixing mechanism horizontal feed to be inserted into space between 5 top surface of rack for test tube.
Specifically, the above-mentioned detailed process for mix operation to peripheral blood test tube includes the steps that S31- as shown in Figure 9
S33, before introducing corresponding the step of mixing operation, first to execute the peripheral blood test tube mixing mechanism of mixing operation into
Row is described in detail:
As shown in Figure 10, the peripheral blood test tube mixing mechanism 300: including feed mechanism, third horizontal bracket 21, second
Horizontal bracket 19, brushless motor 24 and eccentric block 26；Test tube storehouse 22, second water are provided on the third horizontal bracket 19
The test tube support with inner sunken face is provided on flat bracket；The test tube support 23 is used to support peripheral blood collecting tube, the test tube
Storehouse 22 is used to test tube being limited in the test tube support 23；The brushless motor 24 of peripheral blood test tube mixing mechanism drives eccentric block 26
Motor shaft around brushless motor 24 is rotated, and then the second horizontal bracket and test tube support is driven to generate rotary swing.
Further, feed mechanism described in the embodiment of the present invention preferably includes: horizontal feed linear motor 13, the level
Feeding 13 motor shaft of linear motor is fixed in the horizontal direction on L shape peripheral blood test tube mixing mechanism pedestal 14, solid on pedestal 14
Surely there is horizontal direction linear guide 15, the sliding part that fixed block 16 is fixed in linear guide 15 corresponds on sliding block, mobile push plate
17 connect with the sliding screw of fixed block 16 and linear motor 13 respectively.
Further, the peripheral blood test tube mixing mechanism 300 further includes first level bracket 18, the first level branch
Frame 18 is fixed on fixed block 16, and 19 flexible rubber shock structure 25 of the second horizontal bracket is fastened on first level bracket 18
Side, and the rubber test tube support 23 with inner sunken face is fixed on the second horizontal bracket 19；Support rod 20 is fixed on the first water
Flat 18 top of bracket, and 20 height of support rod will be crossed higher than the second horizontal bracket 19, accordingly be passed through in the second horizontal bracket 19
Region should have empty avoiding evacuation；Third horizontal bracket 21 be fixed on 20 upper end of support rod and and thereon be fixed with perforation test tube storehouse
22, brushless motor 24 is fixed on 19 top of the second horizontal bracket, eccentric block 26 is fixed on 24 output shaft end of brushless motor, and movement pushes away
It is fixed on plate 17 and moves horizontally position and block optocoupler baffle 27, corresponding horizontal position detection optocoupler 28 is fixed on pedestal 14
On.
300 working principles of peripheral blood test tube mixing mechanism described in the embodiment of the present invention are as follows: in horizontal feed straight-line electric
Under machine 13 drives, the sliding screw of linear motor 13 drives mobile push plate 17, optocoupler baffle 27 and fixed block 16 along level side
It is moved horizontally to the execution of 15 guide direction of linear guide, the first level bracket 18, second that installation is associated on fixed block 16 is horizontal
Bracket 19, support rod 20, third horizontal bracket 21, perforation test tube storehouse 22, test tube support 23, brushless motor 24, flexible rubber damping
Column 25,26 level of synchronization of eccentric block are mobile.Under the driving of brushless motor 24, fixed eccentric block on 24 output shaft end of brushless motor
26 execute rotation around motor shaft；Since the second horizontal bracket 19 of fixed brushless motor 24 is connected by flexible rubber shock structure 25
18 top of first level bracket and 26 rotary shaft hole of eccentric block are fixed on not in its center of gravity, therefore band when the rotation of eccentric block 26
Move the rotary swing of second horizontal bracket 19 and vibration.
Specifically, it is above-mentioned to peripheral blood test tube carry out mix operation detailed process is as follows:
Step S31: control test tube clamp claw clip holds the rising of peripheral blood test tube；
Step S32: control peripheral blood test tube mixing mechanism, which is fed into, mixes position, and the test tube clamp claw clip holds peripheral blood examination
Pipe decline, peripheral blood test tube is placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, peripheral blood test tube bottom and tip
The test tube support of blood test tube mixing mechanism abuts, and test tube clamping jaw execution horizontal feed moves to horizontal ready far from rack for test tube direction
Position；
Step S33: the brushless motor of peripheral blood test tube mixing mechanism drives eccentric block rotation, and then drives perforation test tube support
Rotary swing is generated, causes to set the blood sample in the peripheral vessel abutted with the test tube support and is mixed.
Optionally, it is described executed the corresponding mixing operation of the corresponding peripheral blood test tube of above-mentioned steps S31-S33 after, also
Include the following steps:
Step S34: control test tube clamp claw clip is held the peripheral blood test tube after mixing and is risen, and causes peripheral blood test tube far from described
Penetrate through test tube storehouse；
Step S35: peripheral blood test tube mixing mechanism is executed to be moved far from rack for test tube direction；
Step S36: control test tube clamp claw clip holds the peripheral blood test tube decline after mixing, and the peripheral blood test tube after mixing is put
It returns in rack for test tube.
Optionally, the step S33 further include: the brushless motor of peripheral blood test tube mixing mechanism executes one timing of driving
Between, eccentric block is rotated around motor shaft, and then the second horizontal bracket is driven to generate rotary swing；It is fixed on the second horizontal branch
The test tube in test tube support on frame with inner sunken face, bottom generate rotary swing with the second horizontal bracket.The present invention is real
The test tube that example is fallen in the rubber test tube support 23 with inner sunken face fixed on the second horizontal bracket 19 is applied, bottom is with second
Horizontal bracket 19 generates rotary swing and vibration, and perforation test tube storehouse 22 is opposing stationary constrains test tube pipe shaft, test tube bottom
The opposite swing in portion is larger；To which blood sample reaches blood sample mixed well mesh in centrifugation whipping and the multiple influence of vibration in conjunction under in test tube
, while preventing broken haemocyte.
Optionally, the corresponding mixing operation of the venous blood test tube includes: that test tube clamping jaw lifts from rack for test tube to examination
It manages above rack for test tube, after implementation is mixed by inversion back and forth, then puts test tube and return in rack for test tube and exit test tube clamping jaw.
Optionally, in the step S35, in the case where being identified as venous blood test tube, by the corresponding examination of venous blood test tube
The sampling needle descending depth of tubing type setting executes；When being identified as peripheral blood test tube, set by the test tube type of peripheral blood test tube
The sampling needle descending depth set executes；The sampling needle descending depth of venous blood test tube setting is greater than the sampling of peripheral blood test tube setting
Needle descending depth.
Optionally, the full-automatic sample introduction blood cell analysis measuring device further includes automatic counting module, is used to trigger
For blood sample automatically analyze and counting operation, for the ease of starting, the automatic counting module is provided with as shown in Figure 2
Automatic counting button 1, full-automatic sample introduction is analyzed the measurement for pressing that automatic counting button 1 can start under whole blood mode.Also,
Press automatic counting button 1 be equivalent to inform control unit carried out primary analysis, which can be used for analysis tube
Number carry out statistics or the quantity for checking analysis tube.
As can be seen from the above description, the method and device for implementing the embodiment of the present invention has the following beneficial effects:
The present invention provides a kind of full-automatic sample introduction blood cell analysis measurement method and devices, realize more easy end
Tip blood whole blood test operation mode, first is that being not necessarily to pre-dilution outside the machine of dilution, second is that measurement sample without stringent quantitative requirement
It influences, need to only meet minimum test dosage requirement, such as the measurement method of venous blood, what is provided through the invention is full-automatic
It is automatic on same machine that peripheral blood sample and venous blood sample may be implemented in sample introduction blood cell analysis measurement method and device
Sample introduction completes detection, does not need to detect on different correspondence cellanalyzers respectively, simplifies the operation of medical staff, drops
The cost of Di Liao hospital detection.Present invention method and device can pass through detection unit automatic identification venous samples simultaneously
Product acquire the test tube type of test tube and tip blood sample acquisition test tube, and implement corresponding blood blending manner according to test tube, and
It is sampled analysis automatically according to different test tube type control sampling needles, finally output analysis measurement result.The present invention is implemented
Example provide method and device high degree of automation, release the labor intensity of clinical staff, improve blood sample sample introduction and
The efficiency of detection.
With reference to specific embodiment, although the present invention is illustrated in the specification and illustrated in the drawings, it is to be understood that,
In the case where not departing from the scope of the invention defined in claim, technical field personnel can make it is a variety of change with
And a variety of alternative many of elements of equivalent.Moreover, technical characteristic, element between mode embodied herein and/
Or the combination and collocation of function are clearly apparent, therefore according to these disclosure of that, technical field personnel can
Another embodiment can be optionally incorporated by understanding the technical characteristic in embodiment, element and/or function
In, unless above content has other description.In addition, introduction according to the present invention is fitted in the range for not departing from essence of the invention
Answer special situation or material can be with many modifications may be made.Therefore, the present invention is not limited to graphic of attached drawing institute is other specific
Embodiment and the specific reality described in this description as at present to implement preferred forms contemplated by the present invention
Mode is applied, and the present invention is intended to include all embodiments fallen into description above and scope of the appended claims.
Claims (14)
1. a kind of pair of peripheral blood test tube carries out the method for mixing operation characterized by comprising
Control test tube clamp claw clip holds the rising of peripheral blood test tube；
Control peripheral blood test tube mixing mechanism, which is fed into, mixes position, and the test tube clamp claw clip holds the decline of peripheral blood test tube, will be last
Tip blood test tube is placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, peripheral blood test tube bottom and peripheral blood test tube mixing machine
The test tube support of structure abuts, and test tube clamping jaw executes horizontal feed and moves to horizontal ready bit far from rack for test tube direction；
The brushless motor of peripheral blood test tube mixing mechanism drives eccentric block rotation, and then perforation test tube support is driven to generate rotary pendulum
It is dynamic, cause to set the blood sample in the peripheral vessel abutted with the test tube support and is mixed.
2. carrying out the method for mixing operation to peripheral blood test tube as described in claim 1, which is characterized in that the peripheral blood examination
Pipe includes tube body, and the tube body includes outer tube body and interior tube body, and the bottom of said inner tube body is located at the middle region of outer tube body
Domain, the lower area of outer tube body are light-permeable.
3. carrying out the method for mixing operation to peripheral blood test tube as described in claim 1, which is characterized in that the peripheral blood examination
Pipe further includes pipe cap, and the pipe cap entirety or middle part are rubber material.
4. carrying out the method for mixing operation to peripheral blood test tube as described in claim 1, which is characterized in that said inner tube body
Bottom is set as taper round bottom.
5. carrying out the method for mixing operation to peripheral blood test tube as described in claim 1, which is characterized in that the outer tube body is
Straight flange extends downwardly the skirt of certain length composition along the tube body short transverse above the taper of interior tube body bottom.
6. carrying out the method for mixing operation to peripheral blood test tube as claimed in claim 5, which is characterized in that the skirt is close
Bottom zone is transparent or semitransparent.
7. a kind of full-automatic sample introduction blood cell analysis measuring device, which is characterized in that including control unit, described device further includes
It is connect with described control unit and controls its sample for executing corresponding operating by sending control instruction by described control unit
Platform mechanism, sampling needle, sample introduction dress are exited in analytical equipment, venous blood test tube mixing mechanism, peripheral blood test tube mixing mechanism, unloading
Carrying platform, test tube detection unit, test tube clamping jaw；
Rack for test tube for holding test tubes frame and is fed to sample analysis mechanism by the sample introduction loading platform, so that the sample point
It analyses mechanism and sample analysis measurement is carried out to the invisible spectro blood sample on rack for test tube；
The test tube detection unit is used to detect the loading condition and test tube type of test tube on the rack for test tube；
The sampling needle is used to execute lowering action corresponding with the falling head simultaneously according to the falling head that control unit determines
Sample is drawn so that the device for analyzing samples carries out sample analysis measurement；
The venous blood test tube mixing mechanism and/or peripheral blood test tube mixing mechanism are used for invisible spectro on the rack for test tube
Blood sample carries out mixing operation；
It is described unloading exit platform mechanism for unload exit rack for test tube；
The test tube clamping jaw is for clamping the rising of peripheral blood test tube；
The peripheral blood test tube mixing mechanism mixes position for controlled be fed into, and the test tube clamp claw clip is held under peripheral blood test tube
Drop, the test tube clamping jaw is for peripheral blood test tube to be placed in the perforation test tube storehouse of peripheral blood test tube mixing mechanism, peripheral blood examination
Bottom of the tube is abutted with the test tube support of peripheral blood test tube mixing mechanism, and test tube clamping jaw executes horizontal feed and moves far from rack for test tube direction
To horizontal ready bit；
Peripheral blood test tube mixing mechanism includes brushless motor and eccentric block, and brushless motor drives eccentric block rotation, and then drives and pass through
Logical test tube support generates rotary swing, causes to set the blood sample in the peripheral vessel abutted with the test tube support and is mixed.
8. a kind of full-automatic sample introduction blood cell analysis measuring device as claimed in claim 7, which is characterized in that the test tube inspection
Surveying unit is that any operative position in the mixing position on the sample introduction loading platform or before mixing position can be set to optocoupler is penetrated
On.
9. a kind of full-automatic sample introduction blood cell analysis measuring device as claimed in claim 7, which is characterized in that the peripheral blood
Test tube mixing mechanism includes feed mechanism, at least three horizontal brackets, flexible column, perforation test tube storehouse, the examination with inner sunken face
Conduit saddle, brushless motor and eccentric block, the brushless motor are located on the second horizontal bracket, and the test tube support is located at the second horizontal branch
On frame, the perforation test tube position in storehouse is on third horizontal bracket, and one end of the flexible column connects the first level bracket, separately
One end connects second horizontal bracket.
10. a kind of full-automatic sample introduction blood cell analysis measurement method, which is characterized in that the method is based in claim 7 to 9
Any one described device is implemented, and described method includes following steps:
During sample introduction loading platform traverse feed rack for test tube, the loading condition of the test tube on rack for test tube is determined；
In the case where being mounted with test tube on determining the rack for test tube, the test tube class of the test tube loaded in the rack for test tube is determined
Type, wherein the test tube type includes venous blood test tube and peripheral blood test tube；
Corresponding blending manner is determined according to the test tube type, and invisible spectro blood is carried out using determining blending manner
Mix operation；
When rack for test tube, which is fed into, inhales sample position, falling head is determined according to the test tube type of the determination, sampling needle executes and institute
It states the corresponding lowering action of determining falling head and draws sample；
Analysis measurement is carried out to the sample of absorption, after analysis is measured, rack for test tube is fed to the unloading of unloading position and is withdrawn into unloading
On platform, the analysis measurement result of the sample of absorption is exported.
11. a kind of full-automatic sample introduction blood cell analysis measurement method as claimed in claim 10, which is characterized in that the tip
The tube bottom thickness of blood test tube is greater than the tube bottom thickness of the venous blood test tube, and the tube bottom of the peripheral blood test tube is light-permeable.
12. a kind of full-automatic sample introduction blood cell analysis measurement method according to claim 10, which is characterized in that the end
Tip blood test tube includes outer tube body and interior tube body, and the bottom of said inner tube body is located at the central region of outer tube body, outer tube body
Lower area is light-permeable.
13. a kind of full-automatic sample introduction blood cell analysis measurement method as claimed in claim 10, which is characterized in that the basis
The test tube type determines corresponding blending manner, and carries out mixing behaviour to invisible spectro blood using determining blending manner
Make, further includes:
In the case where the test tube type is venous blood test tube, test tube clamping jaw clamps test tube from rack for test tube and is moved to test tube
Above frame, implementation overturns mix to blood sample back and forth.
14. a kind of full-automatic sample introduction blood cell analysis measurement method as claimed in claim 13, which is characterized in that in the examination
In the case that tubing type is venous blood test tube, rotary speed parameter corresponding with the venous blood test tube, the peripheral blood test tube are determined
The brushless motor of mixing mechanism carries out mixing operation to the invisible spectro blood sample using the rotary speed parameter of the determination.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018103720055 | 2018-04-24 | ||
| CN201810372005 | 2018-04-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110398596A true CN110398596A (en) | 2019-11-01 |
| CN110398596B CN110398596B (en) | 2023-12-01 |
Family
ID=68293754
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910324839.3A Active CN110398596B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sample injection blood cell analysis and measurement method and device and method for uniformly mixing peripheral blood test tubes |
| CN201910325591.2A Active CN110398599B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device |
| CN201910324840.6A Active CN110398597B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device and test tube type determination method |
| CN202011205865.3A Active CN112285369B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device |
| CN202011217859.XA Active CN112326982B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sample injection blood cell analysis measuring device and test tube type determining method |
| CN201920555266.0U Active CN210401441U (en) | 2018-04-24 | 2019-04-22 | Full-automatic sample injection blood cell analysis and measurement device and peripheral blood test tube |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910325591.2A Active CN110398599B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device |
| CN201910324840.6A Active CN110398597B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device and test tube type determination method |
| CN202011205865.3A Active CN112285369B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sampling blood cell analysis and measurement method and device |
| CN202011217859.XA Active CN112326982B (en) | 2018-04-24 | 2019-04-22 | Full-automatic sample injection blood cell analysis measuring device and test tube type determining method |
| CN201920555266.0U Active CN210401441U (en) | 2018-04-24 | 2019-04-22 | Full-automatic sample injection blood cell analysis and measurement device and peripheral blood test tube |
Country Status (2)
| Country | Link |
|---|---|
| CN (6) | CN110398596B (en) |
| WO (1) | WO2019206097A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113607967A (en) * | 2021-09-30 | 2021-11-05 | 宁波奥丞生物科技有限公司 | Test tube sample mixing device for chemiluminescence immunoassay analyzer |
| CN114950218A (en) * | 2022-04-28 | 2022-08-30 | 桂林优利特医疗电子有限公司 | Full-automatic sample blending system and blending method |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112654850A (en) * | 2018-08-24 | 2021-04-13 | 深圳迈瑞生物医疗电子股份有限公司 | Blood sample analyzer and blood sample mixing method |
| CN110686962B (en) * | 2019-11-04 | 2022-06-24 | 无锡博慧斯生物医药科技有限公司 | Mixing device and analysis appearance of test tube |
| CN111157750B (en) * | 2019-12-31 | 2024-03-15 | 深圳开立生物医疗科技股份有限公司 | Automatic sample injection control method and related device |
| CN114054123B (en) * | 2020-07-31 | 2023-04-18 | 深圳市帝迈生物技术有限公司 | Sample analyzer, test tube adapter device |
| CN112415627A (en) * | 2020-12-16 | 2021-02-26 | 深圳市爱康生物科技有限公司 | Test tube detection device and method applied to laboratory assembly line equipment |
| CN113219187B (en) * | 2021-03-17 | 2022-06-17 | 济南国科医工科技发展有限公司 | Automatic supply device of push-pull test tube rack |
| WO2023056625A1 (en) * | 2021-10-09 | 2023-04-13 | 阳普医疗科技股份有限公司 | Uniform mixing mechanism of thromboelastography analyzer |
| CN114236154B (en) * | 2021-11-24 | 2024-04-12 | 昆明金域医学检验所有限公司 | Full-automatic replacement device of whole blood sample collection tube |
| CN114152770B (en) * | 2022-02-09 | 2022-04-29 | 深圳市帝迈生物技术有限公司 | Sample analyzer and detection process thereof |
| CN114354957B (en) * | 2022-03-18 | 2022-08-23 | 深圳市帝迈生物技术有限公司 | Sample analyzer field cleaning method and sample analyzer |
| CN114460321A (en) * | 2022-04-14 | 2022-05-10 | 深圳市帝迈生物技术有限公司 | Sample analyzer and test tube detection assembly thereof |
| CN116242994B (en) * | 2022-12-09 | 2023-10-13 | 中国人民解放军总医院第八医学中心 | Household blood routine automatic analyzer |
| CN117554313B (en) * | 2024-01-10 | 2024-04-02 | 绍兴君鸿智能科技有限公司 | Automatic detection system and automatic detection method |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1932514A (en) * | 2006-09-30 | 2007-03-21 | 江西特康科技有限公司 | Haematocyte analyzer feeding mode and automatic feeding device |
| CN102411059A (en) * | 2010-08-02 | 2012-04-11 | 希森美康株式会社 | Sample processing apparatus |
| CN103237602A (en) * | 2010-12-03 | 2013-08-07 | 贝克顿·迪金森公司 | Specimen collection container assembly |
| CN103760372A (en) * | 2013-12-26 | 2014-04-30 | 杭州中翰盛泰生物技术有限公司 | Full-automatic immediate check meter |
| CN103901220A (en) * | 2014-04-02 | 2014-07-02 | 长春迪瑞医疗科技股份有限公司 | Device for automatically clamping, shaking up and puncturing |
| CN104502178A (en) * | 2015-01-07 | 2015-04-08 | 深圳市帝迈生物技术有限公司 | Full-automatic testing tube liquid sample blending device and hematology analyzer |
| CN204723071U (en) * | 2015-06-17 | 2015-10-28 | 江苏康健医疗用品有限公司 | Trace peripheral blood collecting tube |
| CN107167344A (en) * | 2017-07-05 | 2017-09-15 | 四川迈克生物医疗电子有限公司 | Inhale sample system and sample analyser |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60162955A (en) * | 1984-02-03 | 1985-08-24 | Hitachi Ltd | Automatic analysis device for blood cell |
| JPH0536364U (en) * | 1991-10-22 | 1993-05-18 | 東亜医用電子株式会社 | Sample container |
| JP2002361061A (en) * | 2001-06-12 | 2002-12-17 | Japan Tobacco Inc | Shaking apparatus |
| CN2820177Y (en) * | 2005-06-16 | 2006-09-27 | 赵缜 | Peripheral blood routine examination specimen container |
| JP5216007B2 (en) * | 2007-07-12 | 2013-06-19 | シスメックス株式会社 | Sample container |
| CN201251579Y (en) * | 2008-09-11 | 2009-06-03 | 杭州迪安医学检验中心有限公司 | Special test tube for a full automatic biochemical immunity analyzer |
| CN101603968B (en) * | 2009-07-14 | 2011-12-21 | 重庆天海医疗设备有限公司 | Closed automatic detection device for blood rheology measurement |
| CN102095841B (en) * | 2011-01-27 | 2013-05-08 | 桂林优利特医疗电子有限公司 | Automatic single sample introduction device of blood cell analyzer |
| CN102151510B (en) * | 2011-02-14 | 2012-12-19 | 四川迈克生物科技股份有限公司 | Mixing device |
| CN103364577B (en) * | 2012-03-29 | 2014-11-26 | 深圳市开立科技有限公司 | Feeding and sampling device for hematology analyzer |
| JP2014128329A (en) * | 2012-12-28 | 2014-07-10 | Aso Corp | Photoelectric pulse wave analysis method and photoelectric pulse wave analysis device for peripheral arterial vessel |
| CN203630149U (en) * | 2013-12-26 | 2014-06-04 | 杭州中翰盛泰生物技术有限公司 | Shaking-up device for full-automatic point-of-care testing instrument |
| CN205317799U (en) * | 2015-12-31 | 2016-06-15 | 四川奥博生物医学电子有限公司 | Automatic sampler |
| CN205656132U (en) * | 2016-04-14 | 2016-10-19 | 深圳市帝迈生物技术有限公司 | Detection apparatus for intraductal reagent that has or not |
| CN105854976B (en) * | 2016-05-04 | 2017-11-21 | 安徽省华腾农业科技有限公司 | Staged automatic identification rack for test tube and test tube identification alarm method |
| CN107121559B (en) * | 2017-05-09 | 2018-11-23 | 深圳市帝迈生物技术有限公司 | The measurement method and device of full-automatic sample introduction blood cell analysis can be carried out to peripheral blood |
| CN207215844U (en) * | 2017-08-22 | 2018-04-10 | 深圳市帝迈生物技术有限公司 | Auto injection blood analyser and its test tube auto injection identification device |
| CN107807247B (en) * | 2017-10-31 | 2020-12-01 | 威海市妇女儿童医院 | Automatic sample loading and mixing integrated machine for blood vacuum tube |
| CN208140723U (en) * | 2018-04-24 | 2018-11-23 | 深圳市帝迈生物技术有限公司 | A kind of full-automatic sample introduction blood cell analysis measuring device |
| CN208459415U (en) * | 2018-04-24 | 2019-02-01 | 深圳市帝迈生物技术有限公司 | A kind of blood sample automatic mixing device and blood cell analysis equipment |
-
2019
- 2019-04-22 CN CN201910324839.3A patent/CN110398596B/en active Active
- 2019-04-22 CN CN201910325591.2A patent/CN110398599B/en active Active
- 2019-04-22 CN CN201910324840.6A patent/CN110398597B/en active Active
- 2019-04-22 CN CN202011205865.3A patent/CN112285369B/en active Active
- 2019-04-22 WO PCT/CN2019/083737 patent/WO2019206097A1/en active Application Filing
- 2019-04-22 CN CN202011217859.XA patent/CN112326982B/en active Active
- 2019-04-22 CN CN201920555266.0U patent/CN210401441U/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1932514A (en) * | 2006-09-30 | 2007-03-21 | 江西特康科技有限公司 | Haematocyte analyzer feeding mode and automatic feeding device |
| CN102411059A (en) * | 2010-08-02 | 2012-04-11 | 希森美康株式会社 | Sample processing apparatus |
| CN103237602A (en) * | 2010-12-03 | 2013-08-07 | 贝克顿·迪金森公司 | Specimen collection container assembly |
| CN103760372A (en) * | 2013-12-26 | 2014-04-30 | 杭州中翰盛泰生物技术有限公司 | Full-automatic immediate check meter |
| CN103901220A (en) * | 2014-04-02 | 2014-07-02 | 长春迪瑞医疗科技股份有限公司 | Device for automatically clamping, shaking up and puncturing |
| CN104502178A (en) * | 2015-01-07 | 2015-04-08 | 深圳市帝迈生物技术有限公司 | Full-automatic testing tube liquid sample blending device and hematology analyzer |
| CN204723071U (en) * | 2015-06-17 | 2015-10-28 | 江苏康健医疗用品有限公司 | Trace peripheral blood collecting tube |
| CN107167344A (en) * | 2017-07-05 | 2017-09-15 | 四川迈克生物医疗电子有限公司 | Inhale sample system and sample analyser |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113607967A (en) * | 2021-09-30 | 2021-11-05 | 宁波奥丞生物科技有限公司 | Test tube sample mixing device for chemiluminescence immunoassay analyzer |
| CN114950218A (en) * | 2022-04-28 | 2022-08-30 | 桂林优利特医疗电子有限公司 | Full-automatic sample blending system and blending method |
| CN114950218B (en) * | 2022-04-28 | 2024-04-02 | 桂林优利特医疗电子有限公司 | Full-automatic sample mixing system and mixing method |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019206097A1 (en) | 2019-10-31 |
| CN210401441U (en) | 2020-04-24 |
| CN110398597B (en) | 2021-12-10 |
| CN110398599B (en) | 2021-03-19 |
| CN112326982B (en) | 2024-04-19 |
| CN112285369B (en) | 2021-11-23 |
| CN112326982A (en) | 2021-02-05 |
| CN110398599A (en) | 2019-11-01 |
| CN110398596B (en) | 2023-12-01 |
| CN110398597A (en) | 2019-11-01 |
| CN112285369A (en) | 2021-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110398596A (en) | Full-automatic sample introduction blood cell analysis measurement method and device carry out the method for mixing operation to peripheral blood test tube | |
| CN208140723U (en) | A kind of full-automatic sample introduction blood cell analysis measuring device | |
| EP1570274B1 (en) | Analyzer and analysing method and a fluid cartridge | |
| CN111712703B (en) | Sample analyzer and sample analysis method | |
| CN106226541B (en) | A kind of automatic clinical chemistry analyzer of novel low cross contamination | |
| CN107121559B (en) | The measurement method and device of full-automatic sample introduction blood cell analysis can be carried out to peripheral blood | |
| JPH087222B2 (en) | Automatic dispensing dilution device | |
| CN1860359B (en) | Hematological analyzer on whole blood with stirring device | |
| JPH08338840A (en) | Method and apparatus for determination of sedimentation velocity of blood | |
| JP2501460B2 (en) | How to measure hematocrit | |
| US20210223276A1 (en) | Blood sample analyzer, blood sample analysis method and computer storage medium | |
| CN113219188A (en) | Integrated modular structure and equipment for thrombus elasticity and blood coagulation analysis | |
| CN113049800A (en) | Immunoassay analyzer, detection method thereof and computer readable storage medium | |
| CN113791235A (en) | Full-automatic thromboelastogram instrument and blood sample testing method | |
| KR101770679B1 (en) | Method of in vitro automatic diagnostics | |
| CN215768613U (en) | Integrated modular structure and equipment for thrombus elasticity and blood coagulation analysis | |
| CN212872486U (en) | Integrated instrument structure for hemagglutination analysis and blood cell counting | |
| CN112684193A (en) | Shifting block mechanism and blood detection device using same | |
| CN214278206U (en) | Shifting block mechanism and blood detection device using same | |
| CN114460320B (en) | Sample analyzer and sample detection process thereof | |
| CN214225197U (en) | Liquid injection and liquid suction device for measuring chamber | |
| JPS5937722Y2 (en) | reactor | |
| JPH05180851A (en) | Micro specimen sampling method for automatic analyzer | |
| CN113960301A (en) | Full-automatic thrombus elastogram detection device | |
| JPH042964A (en) | Apparatus for inspecting medical liquid sample |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |