JP2014128329A - Photoelectric pulse wave analysis method and photoelectric pulse wave analysis device for peripheral arterial vessel - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a photoelectric pulse wave analysis method and a photoelectric pulse wave analysis device for a peripheral arterial vessel, capable of analyzing a photoelectric pulse wave of a peripheral arterial vessel by a simple and easy method without imposing a load on a subject, and obtaining analysis information effective in decision of the presence/absence of obstruction of the peripheral arterial vessel, a degree of the obstruction and an obstructed region.SOLUTION: A photoelectric pulse wave analysis method and a photoelectric pulse wave analysis device for a peripheral arterial vessel has: a measurement step S1 of irradiating the surface of a lower limb body 10 of a subject with light of a prescribed wavelength, and measuring a reflection light amount or a transmission light amount of the light; a photoelectric pulse wave detection step S2 of detecting a waveform of a photoelectric pulse wave from a change of the reflection light amount or the transmission light amount; and a comparison step S3 of comparing the waveform with a reference waveform. The reference waveform is classified based on the presence/absence of obstruction of the peripheral arterial vessel or a degree of the obstruction.

Description

  The present invention relates to a photoelectric pulse wave analyzing method and a photoelectric pulse wave analyzing apparatus for peripheral arterial blood vessels based on the amount of reflected light or transmitted light from the body surface.

  Peripheral arterial disease (PAD), as represented by obstructive arteriosclerosis, is mainly due to chronic occlusion of large blood vessels, causing coldness in mild cases and necrosis of the lower limbs in severe cases. It is a disease that can be reached. The main methods for diagnosing this peripheral arterial disease include angiography, ankle brachial blood pressure ratio (ABI test), and skin perfusion pressure measurement (SPP test). Among these, angiography is a test that incurs a heavy burden on the subject because it injects a contrast medium and is expensive.

  The ABI test estimates the presence or absence of arterial stenosis or occlusion by measuring the blood pressure of the ankle and upper arm. The measured value varies depending on the type of equipment used, and the upper arm and ankle of the sphygmomanometer band (cuff) Depending on the winding method, an error may occur in the measurement value, and the measurement value may not be correctly diagnosed due to the influence of the sclerosing state of the blood vessel. In addition, it may be a burden on the subject to wrap the cuff and apply pressure.

  The SPP test measures the blood flow in the small blood vessels on the surface of the skin, and takes a long time to measure and cannot identify the occlusion site. Moreover, the operation of the laser sensor used for the measurement is complicated in the SPP inspection, and experience is required for handling. In addition, as with the ABI test, it may be a burden on the subject to apply pressure by wrapping the cuff.

  In addition, as a method for calculating an index of arteriosclerosis, a pulse wave waveform is detected from a change in internal pressure of a sphygmomanometer cuff, and the pulse wave velocity is analyzed to calculate a pulse wave velocity (PWV). How to do is known. As one form of the pulse wave velocity (PWV), the upper arm-ankle pulse wave velocity calculated by analyzing a pulse wave waveform collected from the upper arm and ankle while holding a cuff wound around the upper arm and ankle at a constant pressure. (For example, see Patent Document 1).

When baPWV is used as an index of the degree of arteriosclerosis, it is necessary to attach two cuffs to the upper arm and ankle. Therefore, PWV is measured by attaching a single cuff to the upper arm, and based on the measured PWV. A blood pressure information measuring device that can acquire an index indicating the degree of arteriosclerosis is also known (see, for example, Patent Document 2).
In addition, as a method for measuring the state of arteriosclerosis, the degree of arteriosclerosis is determined from the time when the heart contracts and the time when the pulse wave propagates through the blood vessel from the waveform of the aortic pulse wave and the photoelectric pulse wave of the peripheral artery. There is a method (for example, Non-Patent Document 1).

JP 2011-92556 A JP 2011-177249 A

http://www.nihonkohden.co.jp/iryo/techinfo/pwtt/principle.html

  However, as described in Cited Document 1 and Cited Document 2, in the method of detecting the pulse wave waveform from the change in the internal pressure of the cuff, as in the ABI test and the SPP test, it is subject to applying pressure by winding the cuff. The problem of becoming a burden on the company remains. In addition, there is a problem that accurate measurement cannot be performed because the measurement value varies depending on how the cuff is wound around the upper arm and the ankle.

  In addition, arteriosclerosis based on the measurement of the electrocardiogram described in Non-Patent Document 1 and the measurement of the time required for the pulse wave to propagate through the blood vessels in the aorta and peripheral blood vessels is the average from the heart to the photoelectric pulse wave measurement site. It is only possible to measure arteriosclerosis, and it is not possible to determine the presence or absence of occlusion of peripheral arterial blood vessels or the occlusion site of human blood vessels.

  As described above, the conventional diagnostic method has a problem that the burden on the subject is large, such as injecting a contrast medium or winding a sphygmomanometer band (cuff) around the subject.

  Therefore, the present invention can analyze the photoelectric pulse wave of the peripheral arterial blood vessel without burdening the subject and by a simple method, and determine whether the peripheral arterial blood vessel is occluded, the degree of occlusion, and the occluded site. The present invention provides a photoelectric pulse wave analysis method and a photoelectric pulse wave analysis device for peripheral arterial blood vessels that can obtain effective analysis information.

  In order to solve the above problem, the present invention irradiates a plurality of locations on the body surface of a subject with light of a predetermined wavelength, and measures the reflected light amount of the light reflected at the plurality of locations, Photoelectric pulse wave analysis method and photoelectric pulse wave analysis of peripheral arterial blood vessel, comprising: a photoelectric pulse waveform detection step for detecting a plurality of photoelectric pulse wave waveforms from a change in reflected light amount; and a comparison step for comparing the plurality of waveforms. A device is provided.

  According to the present invention, it is possible to detect, as a waveform of a photoelectric pulse wave, a wave when a change in pressure in a blood vessel that is generated when blood is pushed out to the aortic root by contraction of the heart is transmitted to the distal direction. It is possible to obtain analysis information effective for determining the presence or degree of occlusion of peripheral arterial blood vessels by comparing with a reference waveform classified based on the presence or absence or degree of occlusion of peripheral arterial blood vessels it can. That is, according to the present invention, the presence or absence of occlusion of the peripheral arterial blood vessels or the degree of occlusion can be performed by a simple method without burdening the subject such as injecting a contrast agent or applying pressure by winding a cuff. It is possible to obtain analysis information that is effective for the determination.

  Further, in the photoelectric pulse wave analysis method for peripheral arterial blood vessels of the present invention, the reflected light measurement step is performed from the group of the subject's back of the knee, the front side of the ankle, the back side of the ankle, the outside of the ankle, the back of the foot, and the bottom of the foot. One or two or more measured parts to be measured are irradiated with light of a predetermined wavelength, and the amount of reflected light is measured.

  ADVANTAGE OF THE INVENTION According to this invention, the analysis information effective in the presence or absence of the obstruction | occlusion of the peripheral artery blood vessel below a test subject's knee, the degree of obstruction | occlusion, and the obstruction | occlusion site | part can be obtained.

  In the method for analyzing a photoelectric pulse wave of a peripheral arterial blood vessel according to the present invention, the reflected light measurement step includes one or more selected from a group in the vicinity of an artery before the artery of the upper limb of the subject branches and a portion in the vicinity of the branched portion of the artery. The measurement site is irradiated with light of a predetermined wavelength, and the amount of reflected light of this light is measured.

  ADVANTAGE OF THE INVENTION According to this invention, the analysis information effective in the presence or absence of the peripheral artery blood vessel of a test subject's upper limb, the degree of obstruction | occlusion, and determination of an obstruction | occlusion site | part can be obtained. In addition, since the cuff wraps around the entire arm and ankle, the presence or absence of occlusion / stenosis for each blood vessel after branching could not be determined. The presence or absence of stenosis can be determined, and the blood vessel in which occlusion / stenosis has occurred can be accurately identified.

  Further, in the method for analyzing a photoelectric pulse wave of a peripheral arterial blood vessel of the present invention, the comparison step is based on one or more comparison targets selected from a group of a peak position of the waveform, a magnitude of an amplitude, and a waveform pattern. Compare with reference waveform.

  According to the present invention, the waveform can be quantitatively compared with the peak position or amplitude of the photoelectric pulse wave, while the waveform can also be qualitatively compared with the pattern of the photoelectric pulse wave. Multifaceted analysis of waves can be performed.

  Moreover, in the photoelectric pulse wave analysis method for peripheral arterial blood vessels according to the present invention, the reflected light measurement step measures the amount of reflected light from two or more measurement sites in each lower limb, and the comparison step includes each measurement target. A waveform change detecting step is provided for detecting a change in the waveform by comparing the waveforms of the parts.

  According to the present invention, it is possible to detect a change in waveform at two or more measured sites in each lower limb of a subject, and to obtain analysis information effective for determining a blocked site of a peripheral artery blood vessel. .

  In the method for analyzing a peripheral artery blood vessel in the present invention, the light having the predetermined wavelength is infrared light.

  According to the present invention, infrared light applied to the surface of the lower limbs of the subject reaches the deep part of the skin, and the waveform of the photoelectric pulse wave can be reliably detected.

  In the method for analyzing a photoelectric pulse wave of a peripheral artery blood vessel of the present invention, the reference waveform is classified based on a correlation with a value of skin perfusion pressure (SPP).

  According to the present invention, by comparing the waveform of the photoelectric pulse wave detected from the subject with the reference waveform, the correlation between the waveform of the photoelectric pulse wave detected from the subject via the reference waveform and the SPP value can be obtained. it can. Since the magnitude of the SPP value represents the degree of peripheral artery disease (PAD), the degree of PAD disease can be quantified based on the waveform of the photoelectric pulse wave, Effective analysis information can be obtained for determining the degree of occlusion.

  According to the photoelectric pulse wave measuring method of the present invention, the peripheral arterial blood vessel is blocked or not blocked by a simple method without burdening the subject such as injecting a contrast medium or applying pressure by winding a cuff. It is possible to obtain analysis information that is effective for determining the degree and the obstruction site.

The flowchart which shows one Example of the photoelectric pulse wave measuring method which concerns on this invention. The block diagram which shows one Example of the apparatus used for the photoelectric pulse wave measuring method. The figure which shows the artery of a leg body. The figure which shows one Example of the irradiation part of infrared light. The figure which shows one Example of the irradiation part of infrared light. The figure which shows the peak position of a photoelectric pulse wave. The figure which shows the amplitude of a photoelectric pulse wave. The figure which shows an example of the pattern change of a photoelectric pulse wave.

  Embodiments of the present invention will be described based on examples shown in the drawings.

  In the method for analyzing a peripheral arterial blood vessel according to the present invention, a reflected light measuring step S1 for irradiating a surface of a lower limb 10 of a subject with light of a predetermined wavelength and measuring a reflected light amount of the light, and a change in the reflected light amount. A photoelectric pulse waveform detecting step S2 for detecting a waveform of the photoelectric pulse wave from the reference signal, and a comparing step S3 for comparing the waveform with a reference waveform, wherein the reference waveform indicates whether or not the peripheral arterial blood vessel is occluded or the degree of occlusion. It is classified based on. Note that, as an example of using the reflected light amount in the reflected light measurement step S1, the following description will be made on the lower limb. On the other hand, examples of using the transmitted light amount include a fingertip that does not need to penetrate deeply inside the living body.

  The photoelectric pulse wave is a wave that is generated when the blood pressure is pushed to the origin of the aorta due to the contraction of the heart and is transmitted to the distal direction. It is drawn and obtained by irradiating the subject with a certain amount of light, detecting the remaining light other than the light absorbed by blood as reflected light, and measuring the fluctuation component.

  FIG. 2 is a diagram showing an embodiment of the device configuration of the photoelectric pulse wave measuring apparatus used in the method for measuring the photoelectric pulse wave of the peripheral arterial blood vessel according to the present invention. In the illustrated embodiment, the photoelectric pulse wave measuring apparatus has a measurement terminal 12 to be worn on the surface of the lower limb body 10 of a subject and a light shield 11 covering the periphery of the measurement terminal 12, and the reflected light measurement by the measurement terminal 12 is performed. The computer 13 analyzes the change in the amount of reflected light obtained by the above, and detects the waveform of the photoelectric pulse wave.

  The measurement terminal 12 includes, for example, a light emitting element that emits light of a predetermined wavelength such as infrared light, and a light receiving element that receives light such as a photodiode or a phototransistor. Light is irradiated and the reflected light is measured. The light shielding body 11 is made of, for example, a light shielding cloth and covers the periphery of the measurement site to eliminate the influence of light from the outside such as an indoor fluorescent lamp. As the irradiation light, it is preferable to use infrared light since the light reaches the deep part of the skin and the waveform of the photoelectric pulse wave can be reliably detected. However, the irradiation light is not limited to infrared light.

  The computer 13 includes a control unit 14 that controls the measurement terminal 12, an analysis unit 15 that detects and analyzes the waveform of the photoelectric pulse wave from a change in the amount of reflected light measured by the measurement terminal 12, and a storage unit that stores a reference waveform 16 is provided. Moreover, it has the function to control the irradiation part of this invention, a measurement part, a detection part, and a comparison part. The control unit 14 controls the amount of infrared light irradiated from the measurement terminal 12 and the irradiation time. The analysis unit 15 compares the detected waveform of the photoelectric pulse wave with the reference waveform stored in the storage unit 16 based on the peak position of the waveform, the magnitude of the amplitude, and the waveform pattern. The storage unit 16 stores, as a reference waveform, a waveform of a photoelectric pulse wave that verifies the relationship with the presence or absence or degree of occlusion of peripheral arterial blood vessels. Based on classification. In the embodiment, the storage unit 16 classifies and stores the reference waveform based on the correlation with the value of the skin perfusion pressure (SPP).

  Next, the photoelectric pulse wave analysis method for peripheral arterial blood vessels according to the present invention will be described.

  As shown in FIG. 3, the arteries of the lower limbs of a person branch from the thigh to the knee under the anterior tibial artery 21, the posterior tibial artery 22, and the radial artery 23, and the anterior tibial artery 21 further extends from the ankle to the foot. The dorsal artery 24 and the posterior tibial artery 22 are connected to the plantar artery 25. In the lower limbs below the knee, in order to obtain effective analysis information for determining the presence or absence of the peripheral arterial blood vessels, the degree of occlusion or the site of occlusion, the measured site of photoelectric pulse wave is for each of the left and right lower limbs, Back of knee 1, anterior ankle 2 (subject to blood vessels near the body surface governed by anterior tibial artery 21), posterior ankle 3 (subject to blood vessels near the body surface governed by posterior tibial artery 22), It is preferable that there are six locations, namely, the ankle outer side 4 (the target is a blood vessel group near the body surface governed by the radial artery 23), the foot back 5 and the sole 6 (FIGS. 4 and 5).

  Note that the measurement site may be any one or 2 to 5 locations of the knee back portion 1, the ankle front side portion 2, the ankle rear side portion 3, the ankle outer side portion 4, the foot dorsal portion 5, and the sole portion 6. Good. Further, the measurement site is not limited to the site shown in FIGS. 4 and 5, and seven or more sites may be selected.

  As shown in FIG. 1, the photoelectric pulse wave analysis method for peripheral arterial blood vessels includes a reflected light measurement step S1 in which the irradiation unit irradiates the surface of the lower limb body 10 of the subject with a predetermined wavelength and measures the amount of reflected light of the light. And a photoelectric pulse waveform detection step S2 for detecting the waveform of the photoelectric pulse wave from the change in the amount of reflected light, and a comparison step S3 for comparing this waveform with the reference waveform.

  In the reflected light measurement step S1 by the measurement unit, the photoelectric pulse wave measuring device shown in FIG. 2 is used, and the subject's body posture is resting in the prone position, and measurement is performed on the left and right lower limbs.

  As shown in FIGS. 4 and 5, the photoelectric pulse waves are measured at the lower limbs on the left and right legs, as shown in FIGS. 4 and 5. The measurement terminals 12 are attached to the six portions to be measured, and the photoelectric pulse waves for 5 seconds are collected. At the time of measurement, in order to eliminate the influence of light from the outside such as an indoor fluorescent lamp, the periphery of the measurement site is covered with a light shielding body 11 such as a light shielding cloth.

  The measurement terminal 12 irradiates each measurement site with infrared light of a predetermined light amount for 5 seconds and measures the reflected light. A photoelectric pulse wave consisting of a change in the amount of reflected light for 5 seconds measured by the measurement terminal 12 is stored in the storage unit 16 of the computer 13.

  The photoelectric pulse waveform detection step S2 by the detection unit separates the photoelectric pulse wave included in the recording time (5 seconds) for each beat at each measurement site, and adds the average, normalization, etc. to the obtained waveform. Perform processing to shape the waveform. For example, noise can be removed by averaging the waveforms of photoelectric pulse waves of a plurality of beats separated for each beat. The waveform of the photoelectric pulse wave subjected to this waveform shaping process is stored in the storage unit 16 as a comparison target with the reference waveform.

  In the comparison step S3 by the comparison unit, the waveform of the photoelectric pulse wave subjected to the waveform shaping process in the photoelectric pulse waveform detection step S2 is compared with the reference waveform stored in the storage unit 16. This comparison is performed in the analysis unit 15 of the computer 13, and in the case of the embodiment, the comparison is made based on the peak position of the waveform, the magnitude of the amplitude, and the waveform pattern. Note that the comparison target is not limited to the peak position of the waveform, the magnitude of the amplitude, and the waveform pattern.

  As for the peak position of the waveform, for example, as shown in FIG. 6, the degree to which the peak position of the photoelectric pulse waveform deviates from the pulse wave start position is evaluated as a ratio to the entire pulse wave. In the example of FIG. 6, the peak position is shifted by 22% with respect to the entire pulse wave. The peak position of the whole pulse wave changes depending on whether or not the peripheral artery blood vessel is occluded, and generally the peak position shifts backward as the occlusion progresses. Therefore, the comparison step S3 quantifies this peak position. The evaluation can be compared with a reference waveform classified based on the presence or absence of the peripheral arterial blood vessel or the degree of the occlusion.

  For example, as shown in FIG. 7, the magnitude of the amplitude of the waveform is evaluated based on the degree of attenuation of the pulse wave amplitude. Since the degree of attenuation of the pulse wave amplitude changes depending on whether or not the peripheral artery blood vessel is occluded or the degree of occlusion, the amplitude attenuation generally increases as the occlusion progresses. Can be compared with a reference waveform classified based on whether or not the peripheral artery blood vessel is occluded or the degree of occlusion. That is, the blocking progresses as P1 → P2 → P3 shown in FIG.

  In the waveform pattern, for example, as shown in FIG. 8, the waveform of the photoelectric pulse wave changes depending on whether or not the peripheral artery blood vessel is occluded or the degree of occlusion. Regarding the waveform pattern, the reference waveform is classified into several patterns based on whether or not the peripheral arterial blood vessels are occluded or the degree of occlusion, and the correlation between the comparison target waveform and the classified reference waveform The evaluation enables comparison with a reference waveform.

  The comparison step S3 evaluates the peak position and amplitude magnitude of the photoelectric pulse waveform as a quantitative correlation coefficient, and determines the waveform pattern of the photoelectric pulse wave based on whether or not the peripheral artery blood vessel is occluded or the degree of occlusion. It can be qualitatively evaluated by comparing with the classified reference waveform. For example, the reference waveform is classified into a plurality of waveform patterns by evaluating the correlation between each waveform pattern of the photoelectric pulse wave and the presence / absence level of the peripheral arterial blood vessel evaluated by a known evaluation means. It is. As a known evaluation means, it is preferable to use skin perfusion pressure measurement (SPP test) because the magnitude of the value represents the degree of peripheral arterial disease (PAD).

  Moreover, it is preferable that the comparison step 3 includes a waveform change detection step that detects the change in the waveform by comparing the waveforms of the photoelectric pulse waves at a plurality of measurement sites in each lower limb body 10. By providing the waveform change detection step, the comparison step 3 can not only compare the waveform of the photoelectric pulse wave with the reference waveform but also detect the waveform change of the photoelectric pulse wave at two or more measured sites. In addition, it is possible to obtain analysis information effective for determining the occlusion site of the peripheral artery blood vessel.

  The reference waveform stored in the storage unit 16 is obtained by the following method.

  The photoelectric pulse wave measurement device shown in FIG. 2 is used to detect the waveform of the photoelectric pulse wave for a plurality of subjects whose presence or degree of occlusion of the peripheral arterial blood vessel has been evaluated by a known evaluation means. In a plurality of subjects, a correlation is evaluated between a healthy person and a PAD patient with respect to a difference between a known evaluation means and a waveform of a photoelectric pulse wave. The waveform of the photoelectric pulse wave is evaluated with respect to the waveform peak position, amplitude magnitude, and waveform pattern. Among these, the peak position of the waveform and the magnitude of the amplitude are evaluated as a quantitative correlation coefficient, and the waveform pattern is evaluated for a pattern difference between a healthy person and a PAD patient.

  As a known evaluation means, skin perfusion pressure measurement (SPP test) can be used. Since the magnitude of the SPP value represents the degree of PAD disease, by correlating the change in the SPP value with the change in the waveform of the photoelectric pulse, the waveform of the photoelectric pulse is occluded in the peripheral arterial blood vessel. And can be stored in the storage unit 16 as a reference waveform.

DESCRIPTION OF SYMBOLS 1 Knee back part 2 Ankle front part 3 Ankle rear part 4 Ankle outer part 5 Foot back part 6 Foot bottom part 10 Lower limb 11 Shading body 12 Measuring terminal 13 Computer 14 Control part 15 Analysis part 16 Storage part 21 Anterior tibial artery 22 Retrotibial artery 23 radial artery 24 foot dorsal artery 25 plantar artery S1 reflected light measurement step S2 photoelectric pulse waveform detection step S3 comparison step

Claims (11)

  A measurement step of irradiating a plurality of locations on the body surface of the subject with light of a predetermined wavelength and measuring a reflected light amount or a transmitted light amount of the light at the plurality of locations, and a plurality of photoelectric signals based on a change in the reflected light amount or the transmitted light amount. A photoelectric pulse wave analysis method for peripheral arterial blood vessels, comprising: a photoelectric pulse waveform detection step for detecting a pulse wave waveform; and a comparison step for comparing the plurality of waveforms.   The at least one of the plurality of locations on the body surface is in the vicinity of the artery before branching of the lower limb artery, and at least one other location is in the vicinity of the artery after branching of the artery. 2. A method for analyzing a photoelectric pulse wave of a peripheral arterial blood vessel.   The vicinity of the artery before branching of the lower limb artery, which is at least one of the plurality of points on the body surface, is the back of the subject's knee, and at least one other part is the vicinity of the artery after branching, the anterior side of the ankle, the back of the ankle 3. The method for analyzing a photoelectric pulse wave of a peripheral arterial blood vessel according to claim 2, wherein the measurement part is one or more measured sites selected from the group consisting of a side part, an ankle outer part, a foot back part, and a sole part.   The at least one of the plurality of locations on the body surface is in the vicinity of the artery before the branch of the artery of the upper limb, and at least one other location is in the vicinity of the artery after the branch of the artery. 2. A method for analyzing a photoelectric pulse wave of a peripheral arterial blood vessel.   2. The peripheral arterial blood vessel according to claim 1, wherein the step of comparing the plurality of waveforms is a waveform of a photoelectric pulse wave in the vicinity of an artery before branching and a detected waveform of the photoelectric pulse wave after branching. Photoelectric pulse wave analysis method.   The peripheral arterial vascular photoelectric sensor according to claim 1, wherein the step of comparing the plurality of waveforms compares the waveforms of photoelectric pulse waves after branching of two or more measured sites near the artery after branching. Pulse wave analysis method. A measurement step of irradiating a plurality of light on the body surface of the subject with light of a predetermined wavelength and measuring a reflected light amount or a transmitted light amount of the light, and a photoelectric pulse waveform detecting a waveform of the photoelectric pulse wave from the change in the reflected light amount or the transmitted light amount A detection step, and a comparison step for comparing the waveform with a reference waveform,
The reference waveform is a photoelectric pulse wave analysis method for peripheral arterial blood vessels classified based on whether or not the peripheral arterial blood vessels are occluded or the degree of occlusion.   The photoelectric pulse wave analysis of peripheral arterial blood vessels according to claim 1 or 7, wherein the comparison step performs comparison based on one or more comparison targets selected from a group of the peak position, amplitude magnitude, and waveform pattern of the waveform. Method.   9. The method of analyzing a peripheral arterial blood vessel according to claim 1, wherein the light having the predetermined wavelength is infrared light.   10. The method of analyzing a peripheral arterial blood vessel according to claim 1, wherein the reference waveform is classified based on a correlation with a value of skin perfusion pressure (SPP).   From an irradiation unit that irradiates a plurality of locations on the body surface of the subject with light of a predetermined wavelength, a measurement unit that measures the amount of reflected or transmitted light of the plurality of locations, and a change in the amount of reflected or transmitted light A photoelectric pulse wave analysis device for peripheral arterial blood vessels, comprising: a detection unit for detecting a waveform of a plurality of photoelectric pulse waves; and a comparison unit for comparing the plurality of waveforms.

Images