CN102866083B - Blood pressure measuring method - Google Patents
Blood pressure measuring method Download PDFInfo
- Publication number
- CN102866083B CN102866083B CN201210371625.XA CN201210371625A CN102866083B CN 102866083 B CN102866083 B CN 102866083B CN 201210371625 A CN201210371625 A CN 201210371625A CN 102866083 B CN102866083 B CN 102866083B
- Authority
- CN
- China
- Prior art keywords
- sample
- blood
- position data
- plasma
- measuring device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Abstract
The invention relates to a blood pressure measuring method. The blood pressure measuring method comprises the steps of using a sample adding capillary fluid viscosity measuring device, an automatic control circuit based on a microprocessor and matching programs; injecting the processed to-be-measured blood sample into a sample pipe, and completely separating erythrocyte and plasma; starting the sample adding capillary fluid viscosity measuring device, and collecting first height position data in time when the bottom end of a sample adding probe contacts the liquid level of the plasma; starting an injection pump to extract the plasma at the constant speed, collecting pressure signals corresponding to the plasma viscosity in real time, and collecting second height position data in time when the bottom end of the sample adding probe contacts the liquid level of the erythrocyte; and calculating the blood pressure results of the venous blood sample by the microprocessor according to the first height position data and the second height position data.
Description
Technical field
The present invention relates to the long-pending measuring method of a kind of blood pressure, use adding sample capillary tube fluid viscosity measuring device, automatic control circuit and matcher based on micro processor, apparatus, calculate the long-pending result of blood pressure of venous samples can according to the first height and position data, the second height and position data.
Background technology
Chinese patent 200520104155.6 discloses a kind of fluid viscosity measuring device based on adding sample capillary tube, there is a frame, this frame is provided with sample needle erecting frame, on described sample needle erecting frame, fix a capillary type sample needle, this sample needle is communicated with a sample-adding pump by an application of sample pipeline, on described application of sample needle body or described application of sample pipeline, a pressure transducer is set, this pressure transducer is resolved processor and is electrically connected with one by data line, the described processor that resolves is electrically connected with described sample-adding pump input end by control line, below described capillary type sample needle, sample cup fixator is set, in described sample cup fixator, be provided with tested liquid sample cup and tested liquid sample cup.The present invention has online detection, can immediately obtain testing result, data advantage accurately and reliably.But this patent only can be measured plasma viscosity or whole blood viscosity.Cannot measure plasma viscosity, whole blood viscosity and erythrocyte hematocrit by a machine, therefore, need to propose the long-pending measuring method of a kind of new blood pressure.
Summary of the invention
The object of the present invention is to provide a kind of blood pressure to amass measuring method, use adding sample capillary tube fluid viscosity measuring device, automatic control circuit and matcher based on micro processor, apparatus, calculate the long-pending result of blood pressure of venous samples can according to the first height and position data, the second height and position data.The present invention utilizes the flow difference of static pressure value and plasma flow using dynamic and static pressures value of red blood cell, and the height value of detection red blood cell component in sample tube also calculates packed cell volume.The present invention is easy and simple to handle, and the data of measurement are accurate.
The object of the invention is to be realized by following technical proposals: a kind of blood pressure amasss measuring method, use adding sample capillary tube fluid viscosity measuring device, automatic control circuit and matcher based on micro processor, apparatus, the long-pending step of measuring of blood pressure is:
A, a sample tube of the rear injection of venous samples can anti-freezing processing that will be to be measured, generate anticoagulated whole blood, to the processing of described sample tube mark, by described anticoagulated whole blood centrifugal treating, makes red blood cell separate completely and be kept at blood plasma in described sample tube;
B, the described sample tube of preserving red blood cell and blood plasma is put into sample pipe support, start adding sample capillary tube fluid viscosity measuring device, the mouth of pipe of the sample needle in described fluid viscosity measuring device and described sample tube aligns;
C, the described sample needle of order at the uniform velocity move downwards along described sample tube, and in the time that described sample needle bottom touches the liquid level of blood plasma, described automatic control circuit instantaneous acquiring the first height and position data are also saved in micro processor, apparatus; In the time that described sample needle bottom touches the liquid level of blood plasma, the syringe pump in described adding sample capillary tube fluid viscosity measuring device starts, and presses constant flow rate and extract blood plasma from described sample tube;
D, in the time that the blood plasma extracting arrives the pressure transducer position in described adding sample capillary tube fluid viscosity measuring device along described sample needle and application of sample pipeline, the described pressure transducer output pressure signal corresponding with this plasma viscosity, described this pressure signal of automatic control circuit instantaneous acquiring is also saved in micro processor, apparatus;
E, in the time that described sample needle bottom touches erythrocytic liquid level, described automatic control circuit instantaneous acquiring the second height and position data are also saved in micro processor, apparatus; The described syringe pump of order quits work;
Calculation procedure in micro processor, apparatus described in f, startup, the blood pressure that calculates described venous samples can according to the first height and position data, the second height and position data amasss result.
The present invention compared with prior art tool has the following advantages:
1, the present invention utilizes the flow difference of static pressure value and plasma flow using dynamic and static pressures value of red blood cell, and the height value of detection red blood cell component in sample tube also calculates packed cell volume.The present invention is easy and simple to handle, and the data of measurement are accurate.
2, the present invention can measure plasma viscosity and packed cell volume simultaneously, has improved measurement efficiency.
Below in conjunction with drawings and Examples, the invention will be further described.
Brief description of the drawings
Fig. 1 is the structural representation of adding sample capillary tube fluid viscosity measuring device;
Fig. 2 is the vertical view of adding sample capillary tube fluid viscosity measuring device.
Embodiment
Embodiment mono-:
Referring to Fig. 1, Fig. 2, blood pressure of the present invention amasss measuring method, uses adding sample capillary tube fluid viscosity measuring device, automatic control circuit and matcher based on micro processor, apparatus, and the long-pending step of measuring of blood pressure is:
A, a sample tube of the rear injection of venous samples can anti-freezing processing that will be to be measured, generate anticoagulated whole blood, to the processing of described sample tube mark, by described anticoagulated whole blood centrifugal treating, makes red blood cell separate completely and be kept at blood plasma in described sample tube; In the present embodiment, venous samples can is generally got 4ml, is centrifuged into blood plasma and red blood cell.The centrifugal 3000rpm that adopts, 30 minutes; Sample tube can adopt the blood flow of BD to become anticoagulant tube; In the present embodiment, red blood cell is the red blood cell of liquid condition, and blood plasma is the blood plasma of liquid condition; Red blood cell separates refer to that the blood plasma of liquid condition, the red blood cell of liquid condition are divided into two-layer up and down completely with blood plasma;
B, the described sample tube of preserving red blood cell and blood plasma is put into sample pipe support, start adding sample capillary tube fluid viscosity measuring device, the mouth of pipe of the sample needle in described fluid viscosity measuring device and described sample tube aligns; Sample pipe support belongs to prior art, in accompanying drawing, does not show;
C, the described sample needle of order at the uniform velocity move downwards along described sample tube, and in the time that described sample needle bottom touches the liquid level of blood plasma, described automatic control circuit instantaneous acquiring the first height and position data are also saved in micro processor, apparatus; In the time that described sample needle bottom touches the liquid level of blood plasma, the syringe pump in described adding sample capillary tube fluid viscosity measuring device starts, and presses constant flow rate and extract blood plasma from described sample tube; In the present embodiment, the liquid level of blood plasma detects and adopts capacitance method to detect, and the height that capacitance method detects liquid level belongs to prior art, is not described in detail; The blood plasma liquid level detecting is exactly the sample overall height in sample tube, and the first height and position data refer to the overall height value that red blood cell in sample tube and blood plasma are superimposed; Sample needle downwards at the uniform velocity mobile speed is 1 mm/second, and in the long-pending measuring process of blood pressure, sample needle moves down continuously, and translational speed remains unchanged, and the flow velocity of blood plasma is 1 milliliters/second;
D, in the time that the blood plasma extracting arrives the pressure transducer position in described adding sample capillary tube fluid viscosity measuring device along described sample needle and application of sample pipeline, the described pressure transducer output pressure signal corresponding with this plasma viscosity, described this pressure signal of automatic control circuit instantaneous acquiring is also saved in micro processor, apparatus; Be associated and corresponding relation because this pressure signal and plasma viscosity have, micro processor, apparatus converts this pressure signal to plasma viscosity value (this conversion belongs to prior art) automatically; In the present embodiment, be 140ul(microlitre from sample needle bottom to the volume of pressure transducer entrance);
E, sample needle at the uniform velocity move downwards along described sample tube, and in the time that described sample needle bottom touches erythrocytic liquid level, described automatic control circuit instantaneous acquiring the second height and position data are also saved in micro processor, apparatus; The described syringe pump of order quits work;
In the present embodiment, because viscosity number and the red blood cell viscosity number of blood plasma differ widely, in the time that described sample needle bottom touches erythrocytic liquid level, red blood cell enters sample needle immediately, this red blood cell enters the moment of sample needle, there is transition in the pressure signal of pressure transducer output, micro processor, apparatus learns that according to the pressure signal of transition sample needle bottom touches erythrocytic liquid level, these height and position data of automatic control circuit instantaneous acquiring (the second height and position data) immediately; The second height and position data refer to the erythrocytic height value in sample tube; In the present embodiment, the measurement of the first height and position data and the second height and position data is all (sample tube bottom is vertical true origin) taking sample tube bottom as reference field; The long-pending environment temperature of measuring of blood pressure is 25 DEG C-35 DEG C;
Calculation procedure in micro processor, apparatus described in f, startup, the blood pressure that calculates described venous samples can according to the first height and position data, the second height and position data amasss result.In the present embodiment, blood pressure is long-pending is the ratio of the second height number and the first height number.
Referring to Fig. 1, Fig. 2, in described adding sample capillary tube fluid viscosity measuring device, there is a sample needle 2, the top (outlet) of sample needle is connected with one end of application of sample pipeline 201, the application of sample pipeline other end is connected with tee pipe fitting 202 entrances, on tee pipe fitting, settle a pressure transducer 3, tee pipe fitting outlet is connected with solenoid valve 6 entrances by drawing liquid pipeline 301, syringe pump connector is set on solenoid valve, bottle for handling liquid toilet or cosmetic substance connector, bottle for handling liquid toilet or cosmetic substance 5 is connected with the bottle for handling liquid toilet or cosmetic substance connector on solenoid valve by discharge pipe 501, syringe pump 7 is connected with the syringe pump connector on solenoid valve by pipeline, the signal output part of pressure transducer is connected with micro processor, apparatus, automatic control circuit is connected with micro processor, apparatus, automatic control circuit and micro processor, apparatus belong to prior art, be not described in detail.In the present embodiment, tee pipe fitting is a T-valve, and its model is SMC LVM102R; Pressure transducer model is the 26pca of Honeywell, and syringe pump is her rattan syringe pump, and its model is: 1-2586.
In the present embodiment, in adding sample capillary tube fluid viscosity measuring device, there is a jacking gear, this jacking gear has a base 8, base one side arranges vertical rack 802, upright guide rail 803 and lifting screw 804 are set on this vertical rack, lifting support 805 is installed on upright guide rail and lifting screw, a column 9 is set on lifting support, column top arranges a swing arm 4, swing arm motor is set in swing arm, this motor can drive swing arm to swing along surface level, lifting screw bottom is connected with lifting motor 801 power by driving belt, lifting motor drives lifting screw to rotate, thereby drive lifting support to realize lifting, lifting motor and swing arm motor all adopt stepper motor.The object that adopts stepper motor is accurately to control the shift position of sample needle, accurate measure venous blood sample height number.In the present embodiment, sample tube 1 adopts the blood flow of BD to become anticoagulant tube, and sample tube is blood plasma 101 at the middle and upper levels, and lower floor is red blood cell 102.
Claims (1)
1. the long-pending measuring method of blood pressure, is used adding sample capillary tube fluid viscosity measuring device, automatic control circuit and matcher based on micro processor, apparatus, and the long-pending step of measuring of blood pressure is:
A, a sample tube of the rear injection of venous samples can anti-freezing processing that will be to be measured, generate anticoagulated whole blood, to the processing of described sample tube mark, by described anticoagulated whole blood centrifugal treating, makes red blood cell separate completely and be kept at blood plasma in described sample tube;
B, the described sample tube of preserving red blood cell and blood plasma is put into sample pipe support, start adding sample capillary tube fluid viscosity measuring device, the mouth of pipe of the sample needle in described fluid viscosity measuring device and described sample tube aligns;
C, the described sample needle of order at the uniform velocity move downwards along described sample tube, in the time that described sample needle bottom touches the liquid level of blood plasma, the overall height value that red blood cell in described automatic control circuit instantaneous acquiring sample tube and blood plasma are superimposed i.e. the first height and position data, and are saved in micro processor, apparatus; In the time that described sample needle bottom touches the liquid level of blood plasma, the syringe pump in described adding sample capillary tube fluid viscosity measuring device starts, and presses constant flow rate and extract blood plasma from described sample tube;
D, in the time that the blood plasma extracting arrives the pressure transducer position in described adding sample capillary tube fluid viscosity measuring device along described sample needle and application of sample pipeline, the described pressure transducer output pressure signal corresponding with this plasma viscosity, described this pressure signal of automatic control circuit instantaneous acquiring is also saved in micro processor, apparatus;
E, in the time that described sample needle bottom touches erythrocytic liquid level, i.e. the second height and position data of the erythrocytic height value in described automatic control circuit instantaneous acquiring sample tube, and being saved in micro processor, apparatus; The described syringe pump of order quits work;
Calculation procedure in micro processor, apparatus described in f, startup, the blood pressure that calculates described venous samples can according to described the first height and position data, the second height and position data amasss result.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210371625.XA CN102866083B (en) | 2012-09-29 | 2012-09-29 | Blood pressure measuring method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210371625.XA CN102866083B (en) | 2012-09-29 | 2012-09-29 | Blood pressure measuring method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102866083A CN102866083A (en) | 2013-01-09 |
| CN102866083B true CN102866083B (en) | 2014-06-18 |
Family
ID=47445088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210371625.XA Active CN102866083B (en) | 2012-09-29 | 2012-09-29 | Blood pressure measuring method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102866083B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104483237B (en) * | 2015-01-06 | 2017-02-22 | 陈玉梅 | Multi-sample blood pressure product measuring method and device based on transmissivity changing |
| CN107727647A (en) * | 2017-09-30 | 2018-02-23 | 深圳迈瑞生物医疗电子股份有限公司 | The startup method and biological sample analysis instrument of biological sample analysis instrument |
| CN109011733A (en) * | 2018-07-12 | 2018-12-18 | 安陆恩彼饲料有限公司 | A kind of plasma separating unit |
| CN109917001A (en) * | 2019-02-14 | 2019-06-21 | 盈开生物科技（上海）有限公司 | A method of identification blood layering |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101995364A (en) * | 2009-08-11 | 2011-03-30 | 北京普利生仪器有限公司 | Method and device for detecting blood viscosity and hematocrit by using one instrument |
-
2012
- 2012-09-29 CN CN201210371625.XA patent/CN102866083B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101995364A (en) * | 2009-08-11 | 2011-03-30 | 北京普利生仪器有限公司 | Method and device for detecting blood viscosity and hematocrit by using one instrument |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102866083A (en) | 2013-01-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102866083B (en) | Blood pressure measuring method | |
| CN102661888B (en) | Uniformly mixing method and device for whole blood automatic layer absorbing sample suitable for hemorrheology detection | |
| WO2012064809A1 (en) | Real time measurements of fluid volume and flow rate using two pressure transducers | |
| CN105547937A (en) | Automatic control device for detecting erythrocyte sedimentation rate data | |
| CN103033482B (en) | Full-automatic determining instrument of red blood cell osmotic fragility | |
| CN2826373Y (en) | Oil-gas-water automatic gauging instrument | |
| CN1920526B (en) | Method and equipment for measuring fluid viscosity of capillary pipeline | |
| CN205056043U (en) | A disc micro -fluidic chip for in batches quick examination of pesticide residue | |
| CN205317792U (en) | Automatic wei shi method erythrocyte sedimentation rate appearance of accuracy measuring | |
| CN205246139U (en) | Gas content tester | |
| CN107966578B (en) | Medical rapid biochemical detection system and detection method | |
| CN206038693U (en) | Immunofluorescence chromatography detection device | |
| CN108107173B (en) | Portable handheld water quality detection early warning instrument | |
| CN107643355A (en) | The pressure bottle component of automatic sampler | |
| CN201181277Y (en) | Improved sedimentation tube | |
| CN206057356U (en) | Automatic sampler | |
| EP1092140B1 (en) | Method and apparatus for extracting liquid samples from a closed container | |
| CN203037549U (en) | One-machine determination equipment of whole blood and plasma viscosity and blood sedimentation and hematocrit | |
| CN107449712B (en) | Method and device for detecting reagent in channel and cell analyzer system | |
| CN105973825B (en) | A kind of whole blood biochemistry detection method and device | |
| CN114062209A (en) | Blood analyzer | |
| CN220322872U (en) | Full-automatic sample pretreatment detection device | |
| CN207007788U (en) | A kind of spectrum detection device of liquid | |
| CN101915683B (en) | Metering device | |
| KR101476925B1 (en) | Needle apparatus for measuring the viscosity of the blood |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: 102200 1st, 2nd, 4th and 5th floors, building 3, No. 18, kekeyuan Road, Life Science Park, Changping District, Beijing Patentee after: Beijing Mindray Medical Instrument Co.,Ltd. Address before: 100085 Beijing city Haidian District Qunying Science Park Building 5, two floor East Patentee before: BEIJING PRECIL INSTRUMENT Co.,Ltd. |