CN101991519B - Bacteriostatic lotion and preparation method thereof - Google Patents
Bacteriostatic lotion and preparation method thereof Download PDFInfo
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- CN101991519B CN101991519B CN2010105271463A CN201010527146A CN101991519B CN 101991519 B CN101991519 B CN 101991519B CN 2010105271463 A CN2010105271463 A CN 2010105271463A CN 201010527146 A CN201010527146 A CN 201010527146A CN 101991519 B CN101991519 B CN 101991519B
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Abstract
The invention discloses a bacteriostatic lotion and a preparation method thereof. The bacteriostatic lotion comprises the following raw materials in parts by weight: 0.8-1.6 parts of chlorhexidine acetate (CA), 1.5-2.5 parts of fructus cnidii extraction liquid, 1.5-2.5 parts of khosam extraction liquid, 1.5-2.5 parts of phellodendron extraction liquid, 4-8 parts of polyoxyl stearate (40) (S-40), 1-5 parts of Poloxamer (P-188), 0.5-1.5 parts of borneol, 0.5-1.5 parts of menthol, 1.5-2.5 parts of eucalyptus oil, 20-30 parts of 95% ethanol, 10-15 parts of polyethenoxy ether (AE09), 2-5 parts of 1% cacao brown, 0.5-1.5 parts of 20% glacial acetic acid solution, 15-25 parts of glycerin and 900-1000 parts of purified water. The bacteriostatic lotion has simple process control, good bacteriostatic and antipruritic effect and low cost.
Description
Technical field
The present invention relates to the bacteriostatic lotion field, be specially external bacteriostatic lotion and preparation method thereof and preparation method thereof.
Background technology
Gynaecopathia is claimed gynaecopathia again, is the general designation of female reproductive system commonly encountered diseases, and main gynaecopathia comprises vulva, vagina, hysteropathy, diseases of fallopian tubes, ovarian disease etc.; Gynaecopathia is women's commonly encountered diseases and frequently-occurring disease; But because many people lack due understanding to gynaecopathia, lack health care, in addition various bad life habits etc. to health; Physiological health is descended gradually; Cause some women's diseases to be burdened with, and obstinate, bring great inconvenience for normal life, work.
Common gynaecopathia majority causes that because of bacteria breed washing liquid commonly used is carried out antibacterial, and washing liquid kind common on the market is more, but effect is bad, and cost is higher.
Summary of the invention
The technical problem that the present invention solved is to provide a kind of bacteriostatic lotion and preparation method thereof and preparation method thereof, to solve the problem in the background technology:
The technical problem that the present invention solved adopts following technical scheme to realize:
The bacteriostatic lotion component is formed; And count by weight, raw material is formed as follows: chlorhexidine acetate (CA) 0.8-1.6 part, Fructus Cnidii are got liquid 1.5--2.5 part, Radix Sophorae Flavescentis and are got liquid 1.5--2.5 part, Cortex Phellodendri extracting solution 1.5--2.5 part, polyoxyl (40) stearate (S-40) 4--8 part, Poloxamer (P-188) 1--5 part, Borneolum Syntheticum 0.5--1.5 part, Mentholum 0.5--1.5 part, eucalyptus oil 1.5-2.5 part, 95% ethanol 20-30, part, polyoxyethylene ether (AE09) 10--15 part, 1% KEKEZONG 2--5 part, glacial acetic acid solution 0.5-1.5 part, glycerol 15--25 part, purified water 900--1000 part of 20%.
2. and by following processing step and technological parameter prepare:
(1), with load weighted chlorhexidine acetate 0.8-1.6 part, polyoxyl (40) stearate 4--8 part, Poloxamer 1-3 part is mixed, and gets the ebullient purified water dissolving of 55--65 part, and stirs, and is subsequent use;
(2), with load weighted Fructus Cnidii get liquid 1.5--2.5 part, Radix Sophorae Flavescentis is got liquid 1.5--2.5 part, Cortex Phellodendri extracting solution 1.5--2.5 part and Borneolum Syntheticum 0.5--1.5 part, Mentholum 0.5--1.5 part, eucalyptus oil 1.5-2.5 part, and is subsequent use;
(3), Poloxamer 1-2 part is fully dissolved adding (2), stirring, mixing with ethanol 10-15 part of 95%;
(4), ethanol 10-15 part of remaining 95% is added in the mixture of polyoxyethylene ether (AE09) 10--15 part and glycerol 15--25 part, stir, add (3), stirring adds purified water 800-900 part again, mixes;
(5), the mixture of (1) gained is slowly added in (4), stir fast, add KEKEZONG 2--5 part toning of 1%, and add glacial acetic acid solution 0.5-1.5 part of 20% and regulate PH to 4--5, promptly get bacteriostatic lotion.
In the present invention, the optimum weight proportioning is following: 1.2 parts of chlorhexidine acetates (CA), Fructus Cnidii are got 2.0 parts of liquid, Radix Sophorae Flavescentis and are got 3.6 parts of 2.0 parts of liquid, 2.0 parts of Cortex Phellodendri extracting solution, 6 parts of polyoxyl (40) stearate (S-40), 3 parts of Poloxamer (P-188), 1 part of Borneolum Syntheticum, 1 part of Mentholum, 1.9 parts of eucalyptus oils, 25 parts of 95% ethanol, 13 parts of polyoxyethylene ether (AE09), 1% KEKEZONG, 20% 20 parts of 0.748 part of glacial acetic acid solution, glycerol, 950 parts of purified water.
Beneficial effect:
The bacteriostatic lotion technology controlling and process that the present invention makes is simple, and bacterio static itching-relieving is effective, and cost is low.
The specific embodiment
Best embodiment of the present invention divides other scheme according to integral body, implements respectively, through embodiment the present invention is specifically described below:
Embodiment 1:
The bacteriostatic lotion component is formed; And count by weight, raw material is formed as follows: 0.8 part of chlorhexidine acetate (CA), Fructus Cnidii are got 1.5 parts of liquid, Radix Sophorae Flavescentis and are got 2 parts of 1.5 parts of liquid, 1.5 parts of Cortex Phellodendri extracting solution, 4 parts of polyoxyl (40) stearate (S-40), 2 parts of Poloxamer (P-188), 0.5 part of Borneolum Syntheticum, 0.5 part of Mentholum, 1.5 parts of eucalyptus oils, 20 parts of 95% ethanol, 10 parts of polyoxyethylene ether (AE09), 1% KEKEZONG, 20% 15 parts of 0.5 part of glacial acetic acid solution, glycerol, 900 parts of purified water.
2. and by following processing step and technological parameter prepare:
(1), with 0.8 part of load weighted chlorhexidine acetate, 4 parts of polyoxyl (40) stearate, 1 part of mixing of Poloxamer is got 60 parts of ebullient purified water dissolvings, and stirred, and is subsequent use;
(2), with load weighted Fructus Cnidii get 1.5 parts of liquid, Radix Sophorae Flavescentis is got 1.5 parts of liquid, 1.5 parts of Cortex Phellodendri extracting solution and 0.5 part of Borneolum Syntheticum, 0.5 part of Mentholum, 1.5 parts of eucalyptus oils, and is subsequent use;
(3), the Poloxamer that will be left 1 part fully dissolves with 10 part 95% ethanol, adds (2), stirs mixing;
(4), remaining 10 part 95% ethanol is added in the mixture of 10 parts of polyoxyethylene ether (AE09) and 15 parts of glycerol, stir, add (3), stir, add 860 parts of purified water again, mix;
(5), the mixture of (1) gained is slowly added in (4), stir fast, add 2 parts of tonings of KEKEZONG of 1%, and add 20% glacial acetic acid solution and regulate PH to 5 for 0.5 part, promptly get bacteriostatic lotion.
Bacteriostatic lotion of the present invention, each once a day 2ml cleans pudendum, can effectively suppress bacteria breed.
Embodiment 2:
The bacteriostatic lotion component is formed; And count by weight, raw material is formed as follows: 1.2 parts of chlorhexidine acetates (CA), Fructus Cnidii are got 2.0 parts of liquid, Radix Sophorae Flavescentis and are got 3.6 parts of 2.0 parts of liquid, 2.0 parts of Cortex Phellodendri extracting solution, 6 parts of polyoxyl (40) stearate (S-40), 3 parts of Poloxamer (P-188), 1 part of Borneolum Syntheticum, 1 part of Mentholum, 1.9 parts of eucalyptus oils, 25 parts of 95% ethanol, 13 parts of polyoxyethylene ether (AE09), 1% KEKEZONG, 20% 20 parts of 0.748 part of glacial acetic acid solution, glycerol, 950 parts of purified water.
2. and by following processing step and technological parameter prepare:
(1), with 1.2 parts of load weighted chlorhexidine acetates, 6 parts of polyoxyl (40) stearate, 2 parts of mixing of Poloxamer are got 55 parts of ebullient purified water dissolvings, and stirred, and are subsequent use;
(2), with load weighted Fructus Cnidii get 2.0 parts of liquid, Radix Sophorae Flavescentis is got 2.0 parts of liquid, 2.0 parts of Cortex Phellodendri extracting solution and 1 part of Borneolum Syntheticum, 1 part of Mentholum, 1.9 parts of eucalyptus oils, and is subsequent use;
(3), the Poloxamer that will be left 1 part fully dissolves with 10 part 95% ethanol, adds (2), stirs mixing;
(4), remaining 15 part 95% ethanol is added in the mixture of 13 parts of polyoxyethylene ether (AE09) and 20 parts of glycerol, stir, add (3), stir, add 895 parts of purified water again, mix;
(5), the mixture of (1) gained is slowly added in (4), stir fast, add 3.6 parts of tonings of KEKEZONG of 1%, and add 20% glacial acetic acid solution and regulate PH to 4.8 for 0.748 part, promptly get bacteriostatic lotion.
Bacteriostatic lotion of the present invention, each once a day 1ml cleans pudendum, can be effectively antipruritic, suppress bacteria breed.
More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; The present invention is not restricted to the described embodiments; That describes in the foregoing description and the description just explains principle of the present invention; Under the prerequisite that does not break away from spirit and scope of the invention, the present invention also has various changes and modifications, and these variations and improvement all fall in the scope of the invention that requires protection.The present invention requires protection domain to be defined by appending claims and equivalent thereof.
Claims (3)
1. the bacteriostatic lotion component is formed; It is characterized in that; Count by weight, raw material is formed as follows: 1.5-2.5 parts of 0.8-1.6 parts of chlorhexidine acetate, Fructus Cnidii extracting solution 1.5--2.5 part, Radix Sophorae Flavescentis extractive liquid 1.5--2.5 part, Cortex Phellodendri extracting solution 1.5--2.5 part, polyoxyl (40) stearate 4--8 part, poloxamer 1--5 part, Borneolum Syntheticum 0.5--1.5 part, Mentholum 0.5--1.5 part, eucalyptus oil, 95% ethanol 20-30, part, polyoxyethylene ether 10--15 part, 1% KEKEZONG 2--5 part, 0.5-1.5 parts of glacial acetic acid solutions, glycerol 15--25 part, purified water 900--1000 part of 20%.
2. bacteriostatic lotion according to claim 1; It is characterized in that weight proportion is following: 3.6 parts of 1.2 parts of chlorhexidine acetate, 2.0 parts of Fructus Cnidii extracting solution, 2.0 parts of Radix Sophorae Flavescentis extractive liquids, 2.0 parts of Cortex Phellodendri extracting solution, 6 parts of polyoxyl (40) stearate, 3 parts of poloxamers, 1 part of Borneolum Syntheticum, 1 part of Mentholum, 1.9 parts of eucalyptus oils, 25 parts of 95% ethanol, 13 parts of polyoxyethylene ether, 1% KEKEZONG, 20% 20 parts of 0.748 part of glacial acetic acid solution, glycerol, 950 parts of purified water.
3. the bacteriostatic lotion method for preparing is characterized in that, processing step is following:
(1), with 0.8-1.6 parts of load weighted chlorhexidine acetate, polyoxyl (40) stearate 4--8 part, 1-3 parts of mixing of poloxamer are got the dissolving of the ebullient purified water of 55--65 part, and stirred, and are subsequent use;
(2), with 1.5-2.5 parts of load weighted Fructus Cnidii extracting solution 1.5--2.5 part, Radix Sophorae Flavescentis extractive liquid 1.5--2.5 part, Cortex Phellodendri extracting solution 1.5--2.5 part and Borneolum Syntheticum 0.5--1.5 part, Mentholum 0.5--1.5 part, eucalyptus oils, subsequent use;
(3), the ethanol with remaining 1-2 parts of usefulness of poloxamer 95% fully dissolves adding (2), stirring, mixing for 10-15 parts;
(4), 10-15 parts of ethanol with remaining 95% add in the mixture of polyoxyethylene ether 10--15 part and glycerol 15--25 part, stir, and add (3), stirring adds 800-900 parts of purified water again, mixes;
(5), the mixture of (1) gained is slowly added in (4), stir fast, add KEKEZONG 2--5 part toning of 1%, and add 20% glacial acetic acid solution and regulate PH to 4--5 for 0.5-1.5 parts, promptly get bacteriostatic lotion.
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CN105106563A (en) * | 2015-09-25 | 2015-12-02 | 万思雄 | Plantain-Sophora lotion having long-acting disinfection without sensitization and preparation method thereof |
CN106511568A (en) * | 2016-12-21 | 2017-03-22 | 南通华津医药保健品有限公司 | Antibacterial lotion achieving skin and vagina cleanliness and preparation method and application thereof |
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CN109453278A (en) * | 2018-12-25 | 2019-03-12 | 赵显梁 | A kind of external application bacteriostatic Chinese medicinal particle and preparation method thereof |
CN110179880A (en) * | 2019-07-09 | 2019-08-30 | 许富明 | A kind of draft bacteriostatic agent and preparation method thereof |
CN110624062A (en) * | 2019-11-02 | 2019-12-31 | 本冠生物科技(上海)有限公司 | Efficient stable antibacterial powder and preparation method thereof |
CN111544354A (en) * | 2020-05-26 | 2020-08-18 | 湖北汇海医药研究所(有限合伙) | Skin bacteriostatic private care solution and preparation method thereof |
CN112022947A (en) * | 2020-09-25 | 2020-12-04 | 长沙市嘉丽美生物科技有限公司 | Bacteriostatic agent based on traditional Chinese herbal medicines and small molecular compounds, and preparation method and application thereof |
CN112220900A (en) * | 2020-09-27 | 2021-01-15 | 大连双迪科技股份有限公司 | Antibacterial lotion and preparation method thereof |
CN115252733A (en) * | 2022-08-29 | 2022-11-01 | 南阳九方中医药有限公司 | Composition for conditioning and maintaining prostate and using method thereof |
CN115778841A (en) * | 2022-12-08 | 2023-03-14 | 刘伟涛 | Anus nursing professional cleaning lotion and preparation method thereof |
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CN100998809A (en) * | 2006-12-28 | 2007-07-18 | 西安仁仁药业有限公司 | Chinese medicine external use lotion for treating woman reproduction system inflammation |
CN101168044A (en) * | 2006-10-26 | 2008-04-30 | 马小歧 | Product formula for lady daily nursing gel |
CN101612258A (en) * | 2009-08-04 | 2009-12-30 | 黄叶清 | A kind of herbal liquid medicine and a kind of antibacterial knitted underwear |
CN101623251A (en) * | 2009-08-11 | 2010-01-13 | 湖北穆兰同大科技有限公司 | Gynecological antibacterial gel bionic propellant |
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CN101168044A (en) * | 2006-10-26 | 2008-04-30 | 马小歧 | Product formula for lady daily nursing gel |
CN100998809A (en) * | 2006-12-28 | 2007-07-18 | 西安仁仁药业有限公司 | Chinese medicine external use lotion for treating woman reproduction system inflammation |
CN101612258A (en) * | 2009-08-04 | 2009-12-30 | 黄叶清 | A kind of herbal liquid medicine and a kind of antibacterial knitted underwear |
CN101623251A (en) * | 2009-08-11 | 2010-01-13 | 湖北穆兰同大科技有限公司 | Gynecological antibacterial gel bionic propellant |
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