CN101990964A - Inflammation-diminishing heart-nourishing tea relieving gynecological inflammation and menopause manic depression - Google Patents

Abstract

The invention relates to gynecological inflammation-diminishing heart-nourishing tea based on a latest scientific result of the cell response of a female central nervous system and a female genital system. The Chinese medicine intelligence in the ancient China is combined with the traditional health-protection concept; gynecological inflammatory virus inhibiting factors contained in organisms and nervous nutrient substances promoting or controlling brain moods are extracted from herbaceous plants which have the effects of allaying excitement and calming mind, diminishing inflammation and protecting health, a right amount of trace elements synthesized in substances promoting the trace elements to have immunologic functions and multiple nutrient factors, i.e. crocin, triterpenoid saponin, cordyceps polypeptide, angelica sinensis polysaccharide, and the like which have the functions of strengthening body health, by applying a modern high-technology biological extraction technology from a macroscopic balance theory of the bioelectrochemistry of a human body to the microcosmic discovery of genetic and molecular levels, and are replenished into an energy system of the human body, thus the effects of diminishing the inflammation, treating a disease and beautifying skin are realized.

Description

A kind of alleviate gynaecological imflammation and climacteric dry strongly fragrant disease the anti-inflammatory tea that nourishes heart

Affiliated technical field

The present invention relates to a kind of rapid rehabilitation that promotes patient's illnesss such as gynaecological imflammation such as cervical erosion, pelvic infecton, vaginitis, adnexitis, the dry strongly fragrant or anxiety that reduction of patient causes is thus also improved plant formula of its sleep quality and preparation method thereof.By the anti-inflammatory of this plant essence allotment tea that nourishes heart, set about from traditional traditional Chinese medical science equilibrium between yin and yang and element culturing fixed folder, raising body immunity, based on biomolecule electrochemistry, gene regulation and cell response technology, with excellent green tea is basic medium, be equipped with the essence that from multiple famous and precious herbal plant, extracts, so can effectively alleviate of the infringement of gynaecological imflammations such as cervical erosion, pelvic infecton, vaginitis, adnexitis to health, especially to menstrual period courses of infection and the QIXUELIANGXU type cervical erosion that causes because of the repeatedly stream of people or production special efficacy is arranged; Simultaneously this drink to silt resistance type irregular menstruation, dysmenorrhoea and Menopause in advance and symptoms such as the common anxiety that is caused, dry strongly fragrant, insomnia good conditioning effect is all arranged.

Background technology

Gynaecological imflammation is a kind of common frdquently encountered disease disease.According to the statistical report of the World Health Organization, the whole world 80% or more adult married women all can suffer from all kinds of gynaecological imflammations of varying degree at different times, adult female's ratio of wherein suffering from cervical erosion in various degree is up to 20%.In recent years, along with the increase of the increasing the weight of of environmental pollution, life stress, the incidence of disease of gynecological disease is in sustainable growth.Survey data shows, China has 70% the women of child-bearing age to suffer from various degree gynecological disease approximately.Variation along with external environment conditions such as social development, work rhythm, life styles, the gynecological disease type has also had obvious change, the incidence of disease of diseases such as ovary variation, endometriosis, pelvic infecton, menopausal syndrome rises rapidly, and young woman's illness rate is also increasing.According to hygiene department statistics, China women's ovary aberration rate is nearly 33% at present, and the incidence of disease of endometriosis rises to about 15%, and the incidence of disease of common gynecological diseases such as pelvic infecton, cervicitis continues to rise.Carried out a women's diseases investigation and unite by " healthy Times " and " 39 healthy net " recently, found that the age less than 30 years old women, once suffered from vaginitis, the proliferation of mammary gland, fibroid and cervical erosion person and all reached more than 50%.The height of illness rate, patient age little all arrived astonishing degree.Along with the development of modern society, politics, the economic status of women in society had comprehensive raising, and the physical and mental health of caring about this colony also becomes society and gives each national substantial responsibility and obligation.

Gynaecological imflammation is a kind of common women's inferior health performance, and the puzzlement that do not accommodate that it brings for numerous women is that a kind of chronicity physiology torments, and also can cause the part women to produce simultaneous phenomenons such as psychological depression or anxiety thus.On the pathogenesis of gynaecological imflammation,, after all, all be based on imbalance of yin and yang, the immunity degradation of body self though its cause has nothing in common with each other.In general, or by the so-called positive unsaturated vapor of traditional Chinese medical science tradition, the seven human emotions too, intemperance of taking food, malnutrition, or by unclean sexuality, the stream of people and production process Chinese traditional medicine or mechanical injuries, or by all multifactor make ovary, the disorders of hormone in vivo mediation function such as microorganism, toxin, chemical substance infringement, radioactive ray and systemic diseases, cause dash appointing hollow, the sea of blood is spill-over on schedule, and even abdominal distension, pain in low back and legs.On the whole, these all are because the human body resistance against diseases is low, kidney qi loss, six external factors which cause diseases invasion and attack, Qi dysfunction in blood control due to.

Studies show that gynaecological imflammation also is to characterize the early stage of all kinds of gynaecology seriously disease.And in the special existing medicine at gynaecological imflammation, doctor trained in Western medicine is mainly with harmful and very easily produce chemical sproof antibiotic, and tens of kinds of Chinese medicine preparations and part that the traditional Chinese medical science only has then that FUKE QIANJIN PIAN, White Phoenix Bolus of Black-bone Chicken, JINJI JIAONANG, HUAHONG PIAN etc. make by traditional Chinese medical science ancient prescription are mixed with synthetic chemistry composition or antibiotic compound medicine.This class medicine all has its corresponding limitation, chemical classes anti-inflammatory antibiotic medicine particularly, can not effect a radical cure gynaecological imflammation and prevent its recurrence or be converted into the severe gynecological disease, can not effectively alleviate by gynaecological imflammation syndrome diseases such as the mental depression of the uncomfortable initiation of inflammatory or anxieties.

The old classical "The Book of Changes" of China thinks that all life entities comprise human body, all be by the interaction of the material of two kinds of different attributes of Yin and Yang and hair tonic, running, survival and apoptosis, thereby the health of human body need keep equilibrium between yin and yang generally.And the explaination of the modern life science of human body yin-yang balancing promptly is meant the balance on the bioelectrochemistry material in the human body.Discover that biological cell is made up of this four big class chemical substance of carbohydrate, lipid, amino acid and protein basically.The organic molecule that constitutes biological cell can show biological electricity polarity feature under varying environment.Constitute protein 20 surplus in the seed amino acid, by the polarity of its biomolecule classify with biological electric charge, it is not charged just can be divided into polarity zone negative electrical charge, polarity zone positive charge and polarity.Contain 550 amino acid residues as haemocyanin, wherein contain 82 of acidic amino acid residues, 99 of alkaline amino acid residues.When the pH value was 4.7, it is not charged that the human albumin just shows as polarity.The uncharged pH value of this polarity is referred to as protein-based " isoelectric point ".Research shows that also the pepsic acidic amino acid/protein molecular in the human body has 37, and basic amino acid/protein molecular has 6, and its isoelectric point is pH1.0; The acidic amino acid of hemoglobin has 53, and basic amino acid has 88, and its isoelectric point is pH6.7; The acidic amino acid of ribalgilase has 7, and basic amino acid has 20, and its electricity such as electricity such as grade is pH9.5.We are according to the electronegative characteristics of the common positively charged alkaline matter of acidic materials, suppose that body temperature is a constant substantially steady state value, so, if in the food of taking in the amino acid contained or protein molecule, the electronegative quantity of polarity is greater than polarity zone positive electricity, the pH value will appear in internal body to be changed, and the variation of acid-base value can have influence on the biologically active of these materials, as the most suitable pepsic pH value is 1.5, the most suitable pH value of lipase is 5.5～5.8, the most suitable pH value of ribalgilase is 7.8, and the most suitable tryptic pH value is 7.7, and the most suitable pH value of arginase is 9.7.Protein molecule is tool biologically active under its most suitable pH value condition, its group or also the rapidest to the speed of dissociating of substrate.Surmount its most suitable pH value, the space structure of its bioprotein enzyme molecule can be destroyed or be changed, and causes its vigor to be affected, and also can make in the body biomolecule be with the positive and negative charge total amount to change simultaneously.And the physics feature that change showed of this quantity of electric charge is the balance of body negative charge and positive electricity or unbalance.Its body electric charge imbalance state and the vital sign that is reflected thereof, it promptly is the imbalance of yin and yang performance of traditional traditional Chinese medical science, thereby also just need use the medicine of warm (acidity, molecular polarity is positively charged) or cold and cool (alkalescence, molecular polarity is electronegative) character to be nursed one's health respectively.Therefore, the modern bioelectrochemistry explaination that traditional traditional Chinese medical science negative and positive mediation is theoretical is that this product is researched and developed a successful extremely important prerequisite.

Modern biotechnology has been found that all metabolic activities of biological cell all are the aerobic activities, and the process that the protein in the cell body, carbohydrate, lipid and amino acid decompose and releases energy is the process of an organic oxidation.In this course, human or animal's cell absorbs oxygen and carries out oxidation reaction by the dissolved oxygen cell delivery in the blood to each position of body by its respiratory system, generates new material and gives off energy and carbon dioxide.The carbon dioxide that is produced in the metabolic process is then taken away and is excreted by blood.If this respiratory of cell body is obstructed,, promptly be the deficiency of vital energy or the blood stasis state that causes body from traditional traditional Chinese medical science viewpoint.Traditional traditional Chinese medical science what is called " pain is then obstructed, and general rule is not bitterly " theory promptly is to carry or transport oxygen, CO in the body circulatory system ₂, nutriment and other metabolite the running of channels and collaterals vascular system be in a kind of improper state.The inflammation of female reproductive system, be because oxygen part in the body and nutriment are supplied with unbalance to a great extent, thereby cause cell normally propagation, metabolism, apoptosis and to absorption, the oxidation of nutriment, modify, transcribe, secrete, degraded, metabolism, transhipment and germ or variation biological tissue be by timely deactivation, or the biological cell remains of apoptosis have failed in time to be cleared, so that bring into play a kind of abnormal condition of its physiological function.

Modern medicine is verified, and under the normal physiological state, the histological anatomy of female reproductive system and biochemistry characteristics are enough to defend the invasion and attack of external microbe.But its immune system is as being destroyed, and then pathogen can be taken advantage of the occasion and be gone into, and borrows all internal and external factors, may cause positions such as vagina, annex, uterine neck, ovary to be inflamed.According to another nearest official's report, China has entered the AIDS high-incidence season at present, and per 4000 philtrums just have a HIV virus carrier in the national population, and every year will be with 30% speed increment.The expert thinks that AIDS has entered the phase that increases fast in China.What should draw attention especially is the unclean probability that will increase infected by HIV of woman vagina.Thereby gynaecological imflammation is a kind of subhealth symptom that never can neglect.

Control for this class gynaecological imflammation, the present invention pays attention to eliminating pathogen to support vital qi and the reinvigoration to body, strengthen immunity of organisms and anti-virus ability with element culturing fixed folder, up-to-date scientific and technological achievement in conjunction with molecular level, gene regulation and cell response in the modern biochemistry, utilize gene technology to regulate and control the suitable acid-base value of the chemical isoelectric substance that produces in the processes such as the secretion of its reproductive system organ cell body related substances, propagation, metabolism, deactivation, degraded and equilibrium between yin and yang on the whole, in the hope of receiving body-building, keeping fit the effect of fair complexion.

It is considered herein that gynaecological imflammation is because qi and blood nutrient normal fortuneization not in reproductive system and the organ-tissue thereof, thereby causes moisture to sink, heat is malicious deposits the result that germ multiplies.With the gynaecology's anti-inflammation health care product that has gone on the market by the high-purity bio-extract as the effectiveness medium different be, the route that the present invention adopts traditional Chinese medicine technology to combine with the modern high technology abstraction technique extracts it and multiplely has a tonifying middle-Jiao and Qi antiphlogistic and bactericidal active ingredient of invigorating blood circulation from pure natural plant.Its technology prerequisite based on the nineties in 20th century since full-fledged biological gene science, scientific payoffs according to gene expression in the female reproductive system and cell response, in conjunction with Chinese traditional traditional Chinese medical science health care theory, find to the microcosmic on the gene level from macroscopic view (negative and positive) equilibrium theory of human body, the production route that combines with the biological abstraction technique of traditional handicraft and modern high technology, from green tea, Chinese caterpillar fungus, safflower, the root of large-flowered skullcap, Asian puccoon, the radix paeoniae rubrathe, the bighead atractylodes rhizome, in the multiple herbaceous plant such as the Radix Astragali, extract it and have the lifting antiviral ability, promote the active ingredient of the oxygen content of blood, thereby reach the disease anti-inflammatory of dispelling, consolidate and set upright, the purpose of body-building.

Summary of the invention:

Gynaecological imflammation is the general name of the multiple reproductive organs mucous membrane inflammatory disease that causes of the different causes of disease.For all associated conditions that reach the treatment gynaecological imflammation and caused, this invention and products thereof is set about from traditional traditional Chinese medical science equilibrium between yin and yang and element culturing fixed folder, based on biomolecule electrochemistry, gene regulation and cell response technology, with excellent green tea is basic medium, be equipped with gynaecology's anti-inflammatory tea of the essence modulation that from multiple famous and precious book on Chinese herbal medicine, extracts, can effectively alleviate of the harmful effect of gynaecological imflammations such as cervical erosion, pelvic infecton, vaginitis, adnexitis, especially body void cervical erosion and the vaginitis that causes because of the repeatedly stream of people or production be had produce effects health and psychology; According to the beverage of this prescription and extracting method preparation thereof, anxiety and the dry strongly fragrant disease common to irregular menstruation, dysmenorrhoea and climacteric all have obvious conditioning effect simultaneously.

This invention solves the technical scheme that its technical problem adopted:

The traditional Chinese medical science thinks that disease for a long time must be empty.So-called empty, be certain class material supply or secrete inadequate a kind of fuselage state in a kind of body tissue.In this state, the anti-virus ability of body and function of immune system are weakened, thereby cause the immunity of organism sexual function can not normal operation, and this is that body void is subject to the external factor influence and the physiological mechanisms of the attitude sign of causing a disease.

Inner inflammatory disease of female reproductive system internal organs and relevant diseases thereof are because the sensory nerve ending rareness that organ surface is distributed in the body is insensitive to mild inflammatory pathology or pain that the internal body initial stage takes place.And to finding or recognize that the unusual or pathology of body takes place, usually be the long period even be in this consumption physical efficiency for many years, reduce the sub-health state of immunity of organisms.The women after marriage, particularly behind the stream of people or postpartum or gynecologic surgery, as not fully nourish conditioning, or cause the initial stage disease of sub-health state Qi dysfunction in blood control due to kidney qi loss, the six external factors which cause diseases invasion and attack by intemperance in sexual life, be various gynaecological imflammations.Thereby we think that the inflammatory sign is the important sign of body void, and on treatment and health care mode, should pay attention to YIN and YANG balance regulating, reinvigoration is prerequisite to strengthen immunity.

The technology path that this invention is adopted promptly is a bioelectrochemistry environment of adjusting body from molecular regulation, gene expression and cellular metabolism, make the environment of the viral cell of multiplying in reproductive system and even the whole machine body destroyed, thereby reach healthy, realize body equilibrium between yin and yang truly.

Principle and mechanism of action

Gynaecological imflammation is the general name of the multiple female sex organ mucous membrane inflammatory disease that causes of the different causes of disease.At the normal physiological state, the histological anatomy of vagina and biochemistry characteristics are enough to defend the invasion and attack of external microbe.If destroyed, then pathogen can be taken advantage of the occasion and be gone into, and borrows all factors, causes colpitis.Under the normal condition, vaginal fluid is acid (mucous plug then is alkalescence in the cervical canal), thereby can suppress activity, the breeding and up of pathogenic bacteria, and inflammation generally is not prone to.When the vaginal fluid acid-base value changes, or when having the specific disease substance to invade, reaction can cause inflammation.The general features of inflammatory reaction is that vulva, vagina have tenesmus and burning heat sensation, and vagina epithelium comes off in a large number, and vagina mucosa hyperemia is touched a tender spot obviously.Occur malaise, underbelly discomfort when serious, the leukorrhea amount is many, be purulence or serosity, and frequent micturition, odynuria can appear in leukorrhea outflow stimulation urethral orifice.If develop into colpomycosis, its outstanding symptom is that leucorrhea increasing and vulva, vagina are very itched, and feels restless when serious, painful unusual, also frequent micturition, odynuria, intercourse pain can be arranged.The leukorrhea stiff bean dregs sample that is white in color, vaginal membranes is treating serious edema caused, and the block film of adularescent sheet adheres to, and easily peels off, even the rotten to the corn substrate of impaired mucous membrane forms shallow table ulcer, it is this sick classical symptom that severe patient can be left over ecchymosis; Another kind of patient's leukorrhea does not have white plates for a large amount of water samples or purulence, and it is rubescent that vagina mucosa is medium degree, oedema, and no serious itch and burning heat sensation only have that vulva is moist to be felt.

The incidence of disease of colpomycosis is only second to trichomonas vaginitis, mainly by due to the candida albicans infection.It is generally acknowledged that Candida albicans is mainly infected and caused by podex, irrelevant with tinea of feet and hands.Certainly, colpomycosis also can be propagated through sexual intercourse.According to statistics, this bacterium parasitism is arranged, non-evident sympton in about 10% non-pregnant woman woman, the 30% pregnant woman's vagina.When adult female's reproductive system local condition is fit to or hygienic habit bad, or the person that uses the antibiotic for a long time causes that easily the vagina acid-base value changes, and candida albicans is bred and causes infection.

Because external factor influence or body ANOMALOUS VARIATIONS, the adult female also situations such as irregular menstruation, dysmenorrhoea can occur.The traditional Chinese medical science thinks that irregular menstruation is many, and resistance against diseases is low because of the positive unsaturated vapor of body, kidney qi loss, six external factors which cause diseases invasion and attack; The seven human emotions too, eating and drinking without temperance, malnutrition, sexual strain fecund, too fat too thin, injury from falling down, all multifactor make ovary, the disorders of hormone in vivo mediation function such as mechanical stimulus and systemic disease, cause dashing and appoint inanition, the sea of blood is spill-over on schedule, and the rule of passing through is not normal and sick.Traditional medicine distinguishes that disease executing control, and thinks that the quality of irregular menstruation should be held up spleen with kidney tonifying, and the vital energy regualting and blood circulation-promoting method is in harmonious proportion qi and blood, YANG promoting growth while YIN promoting generation, and taste are strong, and the prosperous then stream of essence and blood is from smooth.

Chronic cervicitis mostly occurs reproduction age or the vigorous women of ovarian function, because estrogen level increases, makes cervical canal cylindrical epithelial proliferation run off the uterine neck collar extension.Strip off owing to the scaly epithelium on uterine neck surface is dipped in the alkaline inflammation secretion for a long time, strip off very soon, replaced very soon by adapting to the cervical canal cylindrical epithelium of in alkaline environment, growing by adapting in alkaline inflammation secretion.The chronic cervicitis pathogenic process more than childbirth, miscarriage or surgical injury cervix after, invade and cause infection by pathogen.Cervicitis is the women of child-bearing age's a common disease, has acute and chronic two kinds, sees with chronic cervicitis clinically more, is often caused by streptococcus, staphylococcus and enterococcus, and minority also can cause special inflammation because of infective virus, tuberculosis, parasite and actinomyces etc.Chronic cervicitis has multiple performance.As cervical erosion, cervical hypertrophy, cervical polyp, Naboth's cysts etc., wherein see so that cervical erosion more.Can have waist and sacrum pain, lower abdomen to weigh down when the chronic cervicitis inflammation is diffused into pelvic cavity expands and dysmenorrhoea.These symptoms are in menstruation front and back, defecation and sexual intercourse postemphasis.Sometimes also with frequent micturition, dysuria and irregular menstruation, infertile etc.Cervical erosion and cervix cancer have relation closely.Suffer from the patient of cervical erosion, the incidence of cervical carcinoma is much higher than no patients of cervical ruin, so answer active treatment when suffering from cervical erosion.

The traditional Chinese medical science focuses on treats both principal and secondary aspect of disease.We discover: human body is the product that nature is evolved, and is the part of nature.Balance is not only the rule of nature, also is the rule of health.Therefore, human optimal health care pattern should be to keep normal self-repairing capability on the basis that keeps the human body integral balance.This is that one in the traditional Chinese medicine development process innovated greatly, also is " gynaecology's anti-inflammatory nourish heart tea " exclusive feature.It has embodied the material base of the group effect of the health of being healthy and strong in the modern biotechnology.

The present invention from the research and development of molecule, cell level new, to realize really with health, to nourish one's nature, with all worries set aside, be healthy and strong and be purpose, product is a starting point with Yin Yang balancing, element culturing fixed folder, fundamentally change the women because ignore the slight pathology of initial stage reproductive system to the weak situation of the body that finally causes gynaecological imflammation, the trend that takes place in advance of containment Menopause, is improved the functional health tea of female life quality at delaying female aging and raising.This product is soothing the liver, kidney tonifying, accent taste, beneficial vital essence develop simultaneously with nourishing blood, by nourishing blood with regulating the qi flowing in the channels, can promote nucleic acid in vivo protein synthetic, regulate cellular metabolism, improve each internal organs system of body (particularly nerve, endocrine, immunity) function, make these several big systems keep " homeostasis ".It nourishes the proposition of bioelectrochemistry balance theory in the human body from deep layer, comes from deep understanding and development to traditional Chinese medical science yin and yang in equilibrium theory just, is the application of traditional Chinese medical science yin-yang theory in the daily life health care.The scope that deep layer is nourished is multiple, and action pathway also is various.The main mode that deep layer is nourished, be to regulate the amino acid of the different electric charges of band in the human body microcosmos or the concentration of protein molecule, so that reach in the body with the material of negative electric charge and the metastable state that is in dynamic equilibrium with the material of positive electric charge, just do not hindering thereby reach eliminating evil, setting upright and do not stay heresy; Its main purpose is by functional relationships such as the negative and positive of regulating human body, internal organs, qi and bloods, to reach dynamic equilibrium and the harmony between organismic internal environment and body and the environment, particularly make the acid-base value of female reproductive system such as vagina, uterus endocrine environment of living in reach the optimum balance state, make it to realize truly health and health with it.This health care anti-inflammatory contained active component of tea that nourishes heart, immune system, nervous system, E﹠M system, cardiovascular system etc. had regulating action, make these several big systems keep dynamic equilibrium, this is to realize that the human body integral balance keeps the prerequisite of health.Anti-inflammatory nourishes heart that tea not only is confined to single nourishing, toxin expelling, anti-inflammatory, the stasis of blood of invigorating blood circulation, dispel, nourish heart, allay excitement, we can say, in known field, " gynaecology's anti-inflammatory nourish heart tea " founded new thinking, the new model of modern health balanced health medical science, this be this invention and products thereof an exclusive big characteristic.

The married women that grows up is owing to perplexed by gynaecological imflammation, therefore relation between the man and wife will inevitably be involved, and gynaecological imflammation is how unbalance relevant with the female hormone secretion level, and the hormone secretion level is too high or too low, the capital makes on the human physiology and psychologically and all changes, may make inflammatory patients because not good and unable cooking family matters of body condition or easily other people are produced to doubt and avoid, time one is long more can to produce hot-tempered strongly fragrant psychology.The biological factor that this psychology that is caused by gynaecological imflammation makes a variation is associated with dopamine concentration is unbalance among norepinephrine secretion level and the cerebral limbic system.Therefore, this product is in the psychological anxiety and the hot-tempered strongly fragrant sufficient concern that given of conditioning women inflammatory patients.

The principle that the present invention treats both principal and secondary aspect of disease according to the traditional Chinese medical science except that the basic medium that adopts excellent green tea as drink liquid, fully takes into account the synergy of the functional components of following three aspects on its compatibility, so that the patient obtains best health-care efficacy:

1, the composition that has the antibacterial clearing damp effect of anti-inflammatory: with the capsule of weeping forsythia is monarch drug in a prescription, is aided with stamen nelumbini, cape jasmine, feverfew, honeysuckle, the fruit of Cherokee rose, plantain seed, the dried rhizome of rehmannia, the root of large-flowered skullcap, umbellate pore furgus, Poria cocos etc. and helps as minister;

2, the composition that has detoxicating functions promoting blood circulation and removing blood stasis:, be aided with the radix paeoniae rubrathe, daphne odera, corydalis tuber, the red sage root, safflower, peach kernel, the root bark of tree peony, Mitsubishi, the fruit of glossy privet, frutus cnidii, the seed of Chinese dodder, reticulate millettia etc. and help as minister with when being classified as monarch drug in a prescription;

3, have the composition that tonifying middle-Jiao and Qi promotes immunity of organisms: with two American ginsengs is monarch drug in a prescription, is aided with the Radix Astragali, Bai Ren, Radix Codonopsis, the bighead atractylodes rhizome, Cordyceps Militaris, purple sesame, asparagus fern, longan, Chinese ephedra etc. and helps as minister.

Experiment showed, that this drink can significantly improve immunity of organisms,, thereby reach the purpose that anti-inflammatory body-building is allayed excitement and nourished heart by the lifting of immunity of organisms.

The invention has the beneficial effects as follows:

(1) effectively regulates human body negative and positive non-equilibrium state, activate body immunity;

(2) energy is clearing heat and detoxicating, eliminating dampness only is with, stasis-dispelling and pain-killing; Effectively menstruation regulating and relieving dysmenorrhea;

(3) cause that to damp invasion of lower energizer and because of vaginitis, endometritis, adnexitis, pelvic infecton all cards are effective;

(4) can alleviate the erosive colpitis rapidly; The erosive hemorrhage of cervix there is the promote tissue regeneration and stop bleeding effect;

(5) effective Light-headedness and aching pain in waist and back of alleviating by pelvic infecton, cervical erosion and menstrual disorder caused;

(6) regulate mood, alleviate depression, agitation and anxiety keep positive joyful phychology;

(7) regulate biological clock; Promote sleep, improve sleep quality;

(8) improve physical efficiency and tolerance and emergency reaction ability, drive away bad body conditions such as tired sleepiness;

(9) improve antiviral ability; Improve microcirculation, please the residual nuclear of apoptotic cell in face beauty treatment and the efficient removing body.

The explanation of accompanying drawing table

1, major ingredient accounts for 70%.Proportioning is as follows:

Green tea 3%; Radix Angelicae Sinensis 5%; Stamen nelumbini 3%; American ginseng 5%; Radix rehmanniae recen 5%; Poria cocos 5%; Honeysuckle 3%

Purple sesame 5%; Asparagus fern 5%; Mountain, Huaihe River 3%; The Radix Astragali 5%; Cordyceps Militaris 5%; Longan 5%; Feverfew 3%

Glucose, honey, purified water are an amount of

2, auxiliary material accounts for 30%.

The specific embodiment (proportioning and preparation flow)

Choose listed plant finished product in the table (2) from Chinese herbal medicine operator with qualification, do not clean up by assortment, thoroughly remove the impurity sandy soil, brown stain takes place in dry run in order to prevent raw material with purified water, select the saturated vapor of the 0.1～0.2Mpn enzyme that goes out, held time 5～10 minutes; The material coarse cutting that the raw material behind the enzyme of will going out is dried or dried, the granularity of coarse crushing is 3～6 millimeters, drop into extractor, add 10～12 times to the purified water of raw material weight, the purifying electrical conductivity of water is 10～100 μ s/cm, water logging 8～12 hours, be heated to 60～90 degrees centigrade then, stir and extracted 90～120 minutes, filter residue after the extraction drains juice through squeezer to be mixed with extract, left standstill 8～12 hours, place the Chinese medicine ultrafiltration apparatus carry out essence filter clear solution, the extract after the filtration decolours with active carbon.The decolorizer particle diameter is the granular activated carbon of 0.5～1.0mm; consumption is 1～2% of a total amount of liquid; under 55 degree left and right sides temperature conditions Celsius, stirred 15～30 minutes; leave standstill about 1h; use 150～200 order filter clothes to filter; in de-inking solution, add the diatomite of solution total amount 0.5～1.5% before filtering, filter, till obtaining clear and bright limpid solution while mixing.

Concrete classification and operating process are as follows:

(1) raw material that genseng, purple sesame, asparagus fern, the dried rhizome of rehmannia etc. are produced effective ingredient in the raw medicinal material adopts low temperature to soak with the constant temperature water boiling method and extracts its effective ingredient.Be limited to when its heating and temperature control and immersion and poach: the raw material chosen is cleaned to remove impurity such as silt with purified water, soak 12h with 1: 10 ratio of solid-liquid ratio, heating to 85-90 degree Celsius decocted 5 hours, leached to add water after the medicine soup and boiled 3-5 hour again.The gained decoction of medicinal ingredients should be at 9: 1 with the ratio of bulk drug.

(2) the little peptide material of kind of alkalescence is arranged in the corydalis tuber, can effectively block the reuptake of DAT (DAT), make that DA factor density increases between the dopamine neuron cynapse, thereby improve brain awakening degree and learning memory the DA factor.This alkaline little peptide kind material can adopt traditional Chinese medicine to add the warm water extracting method and extract.

(3) there is kind of material can play the dopamine-receptor stimulant effect in the ephedra sinica, for extracting this dopamine-receptor stimulant effective ingredient, must earlier ephedra sinica be pulverized, with 65～85 degrees centigrade of emerge in worm water 24～36 hours, when soaking, must add a small amount of caustic soda, pH value of water solution is maintained about 13.Filter residue mixes the gained soup with other soup.

It should be noted that, boil principle according to traditional Chinese medicine, every kind of medicine boils in the process all in heating can absorption portion other medicines composition, and be not easy to incorporate once more in the decoction of medicinal ingredients, so fibrous root is according to the auxilliary mutually principle of Chinese medicine mutual reinforcement between in preparation process, whole vegetable drugs of this prescription must divide jar preparation in batches, in the hope of obtaining the effective ingredient that maximum is limited the quantity of.

Part biological little molecu-lar mediator material composition and function declaration

1, serotonin:

5-HT (serotonin) claims thrombocytin or serum tension force element again, for monoamine type neurotransmitter, is derived by tryptophane, synthesizes in the enterochromaffin cell of nervous centralis (CNS) unit and animal (comprising the mankind) alimentary canal.Under the physiological pH condition, 5-HT can not break through blood-brain barrier, can not enter in the cell from the pericellular gap, so the synthetic of it can only be in the 5-HT neuron.Synthetic ferrous ion and the O of needing in the body of 5-HT ₂Participate in.

The precursor substance of 5-HT is a tryptophan, and tryptophan is a kind of essential amino acid, can absorb after tryptophan transhipment body is written in the big mesencephalic centre by diet.But because the transporter of transhipment tryptophan equally also can be transported other neutral amino acid such as phenylalanine, serine, glycine, valine, leucine etc., therefore, a key factor of contents level is exactly the relative amount ratio of tryptophan and other neutral amino acid in the food of picked-up in the decision 5-HT neuron.Consequently relevant with 5-HT function behavior is subjected to the influence of diet especially easily.

Discover that thrombocytin participates in the decision process of brain frontal cortex, regulates and control our mood, appetite, sexual desire, awakening, memory and learning activities.It is also relevant with the symptom of many mental illnesses, as depression, anxiety, depression, insomnia, besetment and insanity etc.Studies show that thrombocytin can make most of sympathetic preganglionic neuron excitements, and the parasympathetic preganglionic neuron is suppressed, sensory neuron is also produced inhibitory action, not only can produce the pain sensation to the activation of 5-HT acceptor and suppress, can also cause pain sensation facilitation.Norepinephrine (NA) and serotonin (5-HT) are to keep a pair of cerebral nerve medium that sleep and awake state play a decisive role.Constant or when increasing, the content that reduces 5-HT can cause insomnia when NA content in the brain; Normal or when increasing when 5-HT content in the brain, reduce NA content and then cause drowsiness.Increase 5-HT and discharge or suppress the 5-HT reuptake and can cause that synaptic cleft 5-HT concentration increases and to cause anxiety, on the contrary, exhaust in the brain 5-HT or intercept the 5-HT acceptor then have the effect of alleviating anxiety.Patients with depression and dissect because of depression felo-de-se's brain and to show that 5-HT content is low than the normal person in patient's cerebrospinal fluid.The 5-HT content of high concentration also is to cause one of aggressive lower physiological reason in the cerebral neuron.Aspect the physiology electricity, the neuronic maximum characteristics of 5-HT are discharged slowly and rule exactly, grouping discharge never occurs.Discharge was slowed down when human body was sleepy, can reduce to zero during sleep (particularly slow wave sleep); When giving temporarily to be increased to 5-6Hz when audiovisual stimulates.Emotion such as thrombocytin and obsession and love has substantial connection.In addition, research shows that also the neuronic destruction of serotonergic may be the reason that illusion appears in the psychotic disorder patient.Some researchs in recent years show that again the variation of 5-HT content in brain can influence the change of blood-brain barrier permeability, and the haemoconcentration that increases serotonin helps mediator class material permeance blood-brain barrier.

The acceptor of thrombocytin is known is divided into 7 types, removes 5-HT ₃Outside the receptor, the 5-HT acceptor of all the other types all belongs to G protein couplet superfamily member.5-HT _1BReceptor antagonist can improve because the cognitive disorder of cholinergic neurotransmitter due to losing.Activate 5-HT ₄And 5-HT ₇Acceptor strengthens memory and to waking up of incident in the past.The 5-HT preparation is used to treat GAD more.Other there are some researches show that the 5-HT dysfunction can cause obsession.

The picked-up of 5-HT can be intercepted by some antidepressants, is the extra-heavy inhibitor of 5-HT picked-up as antidepressants such as Prozac, Zoloft and Paxil.But fenfluramine is kind of a more special material, it both can suppress the transhipment of vesica transporter to 5-HT, plasma membrane-bound translocating protein capable of inhibiting cell again is to the transhipment of 5-HT, 5-HT leaks out from synaptic vesicle as a result, accumulate in the kytoplasm, cause cytoplasma membrane transport protein antiport, cause that 5-HT discharges at the end eventually from cellular neural.

2, GABA:

GABA (GABA) is a kind of inhibition type neurotransmitter, mainly has an effect in cerebral cortex, hippocampus, thalamus, basal ganglion and cerebellum, and its main function is to keep the equilibrium of various mediator levels in the cerebral nervous system.GABA is distributed in multiple inhibitory interneuron and projection neuron, about about 30% the cynapse of brain discharges GABA, be more than 1000 times of monoamine neurotransmitters, Purkinje cell layer content at corticocerebral shallow-layer hippocampus and cerebellar cortex is higher, at some position of cerebral cortex, just there is one to discharge GABA in per 5 neurons as neurotransmitter.The GABA effect is extensive, participates in the morbidity of multiple neuropsychiatric disease and the adjusting of pain, neuroendocrine and feeding behaviour; Its function changes or the sex change of GABA serotonergic neuron, and is relevant with epilepsy, Huntingdon syndrome, tardive dyskinesia and sleep-disorder etc.In fact, being positioned at the basal forebrain veutro is that to intersect the special GABA serotonergic neuron of a group in proparea be the necessary biochemical of human sleep.Can systemic-function by strengthening central GABA, can produce calmness, antianxiety and effect such as anticonvulsion.

Studies show that strengthening GABA can treat some anxiety disorder and epilepsy by nervous function, lack GABA and will cause certain nerve cell to be degenerated, thereby the vision selective power is descended.As use the part to check material such as the picrotoxin or the Bic of GABA effect, then can change the receptive field group structure of retinal ganglial cells and cortex complexity.GABA acceptor class medicine such as penicillin are checked in application, can cause tic, and this also shows the importance of the inhibition modulating action that GABA is mediated in the signal transmission of CNS.In addition, GABA has also participated in the activity of brain physiological cycle as a kind of physiologically active ingredient, has mediated the inhibiting nerve conduction of central nervous system more than 64%.It can improve the blood circulation of brain and oxygen is supplied with, stable spirit, promote long-term memory, improve nerve cell old age stupid, alleviate headache, tinnitus that cerebral thrombus, cerebral arteriovenous malformation causes, bring high blood pressure down, the nerve of also can calming, improve arrhythmia cordis, improvement and activation hepatic and renal function.

GABA is synthetic under glutamic acid decarboxylation catalytic action by glutamic acid.Its synthetic and other peptide hormones synthetic the same by gene regulation, and on ribosomes, pass through to translate to synthesize.GABA can help brain at the top.But with advancing age, the GABA that cerebral nerve metasystem obtains replenishes or the interior biosynthesis amount of brain will reduce gradually, and worsening also can appear along with the increase at age in people's visual performance.Positron emission computerized tomography and the research of single photon emission tomoscan show in patient's temporal lobe even whole brain district GABA is arranged all with panic disorder and anxiety patient _AAcceptor BDZ binding site reduces phenomenon, and interior GABA concentration of prompting patient brain and expression are lower than normal healthy controls group.The corresponding reduction of GABA energy inhibition system makes central nervous system excitement-inhibition balance to the skew of excitability direction, thereby has participated in the generation of anxiety disorder.When brain was in fitness form, people can select signal and make a response, and this also is that the study notice can not be concentrated the material base that waits the morbid state generation.

As inhibiting nerve mediator main in the cental system, GABA plays an important role in depression is brought out.Experimental study shows before clinical, and the GABA level reduces in the depression model animal brain, also can observe the reduction of GABA level in clinical emotionally disturbed patient's blood plasma and the cerebrospinal fluid.In the patients with depression brain of committing suiside, can detect the downward modulation of GABA level in addition, and GABA _BThe minimizing of receptor binding site.Studies show that in addition that simultaneously antidepressants and GABA receptor stimulating agent can be by the active performance of GABA serotonergic neuron in brain antidepressant effects, studies show that the effect of GABA in the depression pathogenic process in addition, may be by it and adrenergic and the 5-HT interaction at end eventually, the system that affects the nerves excitement-inhibition balance.

GABA is the acid of a kind of small molecule amine base, and it can make in the brain blood unobstructed, increases the cerebral nervous system oxygen-supplying amount, promotes function of brain cell.GABA summarizes in addition following in fact several functions: (1) prevention senile dementia; (2) alleviate up to about 85% menopause symptom, can suppress the self-disciplining neurological disorder, improve insomnia and have stable effect; (3) improve hypertension, angiocardiopathy, headstroke symptom; (4) effect that activates the kidney function is arranged; (5) activation liver function reduces liver index (GOT, GPT); (6) neutral fat of reduction liver and blood, the prevention fatty liver also prevents obesity; (7) eliminate stink and (8) prevention colorectal cancer.

3, norepinephrine:

NA (norepinephrine) is the same with dopamine, belongs to the catecholamines classical neurotransmitter.It is that precursor is synthetic with tyrosine, and tyrosine hydroxylase and dopamine-B-hydroxylase is the necessary two kinds of enzymes of biochemical reaction process of synthetic NA, NA is mainly synthetic in brain locus coeruleus district, act on Alpha and beta adrenergic receptor, performance important physical effect in multiple functions such as sleep, awakening, attention, learning and memory.Norepinephrine also participates in the morbidity and the process of inhibition of depressed and anxiety disorder.

Discover, participate in synthetic enzyme of brain cental system norepinephrine and receptor sensitivity thereof and all be subjected to hormone and frightened influence; And the gene pleiomorphism of adrenergic receptor may be the considerable influence that is formed with of human makings difference.This important target molecule-cAMP who also means the signal path of NA mediation has also participated in corticocerebral awakening.Being positioned at basal forebrain has the neuronic discharge activities of veutro prechiasma area (vlPOA) of facilitation to sleep, both can be suppressed by acetylcholine, can be suppressed by norepinephrine again, thereby reduce sleep degree and improve arousal level.The former has an effect by m receptor, and the latter is then worked by the NEa-1b acceptor.Norepinephrine concentration is unbalance to cause that drowsiness, body temperature descends, pain reduces and non-essential feeding behaviour.Animal experiment finds that norepinephrine reduces in the brain, can cause mental depression; The norepinephrine excessive concentration then can show manic uneasiness in the brain.Hence one can see that, and norepinephrine is a kind of neurotransmitter with inhibition and excited bidirectional modulation function.

Norepinephrine distributes comparatively extensive in central nervous system, content is more, the tyrosine of biosynthetic raw material sources in blood in its body, the few and active lower tyrosine hydroxylase catalysis by institute's content in the adrenergic fiber cytoplasm, and because O ₂And Fe ^{+ 2}Also be its biosynthesis key element, this just makes the biosynthesis speed of norepinephrine be restricted.Norepinephrine enters the transhipment of nerve ending and can be blocked by cocaine, and tricyclene class antidepressant is the strong inhibition agent of norepinephrine uptake, the effectively degraded of NA in the block nerves system.

4, CAMP:

CAMP (CAMP) is a kind of little molecule with cell internal information transfer function, is called as courier or second messenger in the cell, is that atriphos (ATP) generates under the adenylate cyclase enzymatic.Caffeine makes us keep clear-headed and vigilance by barrier ring AMP acceptor.The precursor that produces adenosine is single AMP (AMP), and it extensively is present in the body tissue, is that signal is led transduction molecule in a kind of cell.CAMP is the interior second messenger of a kind of cell of very easily diffusion, can activate another kind of enzyme---the cAMP dependent kinases.The catalytic subunit mediation phosphate radical of this protein kinase is transferred on the serine and threonine residues of plurality of enzymes and passage from ATP, thereby the activity of modifying them causes the movable increase of calcium channel.Adenosine activates corresponding adenosine receptor and starts the nerve signal transmission mechanism, depends on the G albumen kind of coupling with it, and adenosine receptor then can be divided into the inhibition receptor of adenosine content in the reduction cell and the excitability acceptor of the interior adenosine content of rising cell.

It is synthetic that cAMP has the neurotransmitter of adjusting, promotes the effect of hormone secretion.A large number of experiments show that some secondary trophic hormone promote that secondary hormone is synthetic to be regulated by the cAMP approach.After corticotropin is attached to adrenal cortical cell, activate AC, at the synthetic cAMP of postsynaptic membrane, and then activate PKA, the phosphorylation by memebrane protein changes the permeability of film to ion, thus the excitability of the cell that affects the nerves.Nerve fiber contains high-caliber cAMP and metabolism regulatory enzyme thereof.In brain, spinal cord, cerebrospinal fluid and peripheral nerve, all there are a large amount of cAMP to exist.In vertebrate brain, cAMP content is the highest, and non-nervous tissue is high approximately 10 times, and AC and cAMP phosphodiesterase content are also high 10～20 times than its hetero-organization.More than explanation synthetic and decomposition rate of CAMP in nerve fiber is higher than its hetero-organization far away, and cAMP plays an important role in nerve fiber.In gonad cell, similar situation is also arranged, follicle-stimulating hormone increases the synthetic of estradiol, progesterone by the cAMP approach.CAMP can induce the release of GH, thereby promotes the synthetic of liver internal protein, DNA and RNA, and can strengthen lipolysis, stimulates the synthetic of body protein.

Cyclic adenosine monophosphate is an important function of gene expression regulation material to the adjusting of gene expression: AMP.CAMP is considered to the direct activation RNA polymerase and transcribes promoting in prokaryotes, and promptly the phosphorylation rice of 6 factors by this enzyme realizes promoting that InRNA transcribes.Studies show that in recent years, the effect of cAMP is regulated relevant with transcription factor in the eukaryotic.The palindromic sequence 5 '-TGACGTCA-3 ' that contains 8 base-pairs of unanimity or intimate unanimity around the promoter of the eukaryotic gene of the many cAMP inducible transcriptions of discoveries such as Montndny more, and called after cAMP reaction sequence, be the significant points of these gene identification cAMP signal.Simultaneously, they find that also expression of target gene that cAMP induces also needs the activation of PKA.The cAMP level increases activation PKA, and PKA may carry out phosphorylation by making some special transcription factor again, the gene expression that mediation cAMP causes.Many tests show that PKA can make the histone phosphorylation, and the histone of phosphorylation makes to transcribe and carried out because the change of electriferous state and conformation separates in conjunction with relaxing with DNA, thereby removed the inhibition of histone to this fragment gene.Other has test to find, can make nonhistones phosphorylation at external PKA, and the acidic protein of phosphorylation is acid to be strengthened, have more negative electrical charge, with positively charged histone stronger affinity is arranged and mutually combine, histone is separated with DNA, remove histone preventing of DNA transcribed.

The propagation of the adjusting cell of cyclic adenosine monophosphate on cell proliferation and differentiation is two essential characteristics of cell with differentiation.Propagation comprises growth, dna replication dna and the cell division of cell, realizes by the cell cycle.Differentiation means that intracellular DNA generates InRNA by transcribing, and further synthetic more narrow spectrum protein (enzyme) finally causes each species diversity such as cellular morphology, structure, biochemical composition and function.Cell proliferation is a pair of process that there is harmony as well as contradiction between that both interrelated with differentiation, and cAMP plays an important role in to contradiction regulating this.CAMP has the effect that suppresses cell division, promotes differentiation to isolated cells.Therefore, all factors that the interior cAMP content of cell is raise all can reduce the speed of growth of cell, suppress the propagation of cell, and promote the differentiation of cell.Miyasaki thinks that the cAMP on cell proliferation has double effect, promptly GO or early G1 during the phase on cell proliferation have facilitation, then play inhibitory action during the phase at late G1.

In addition, cAMP and tumour have certain relation, and the cAMP content in normal cell and the tumour cell is discrepant, and cAMP generally is lower than the normal cell level in tumour cell.Can quicken the death of tumour cell when the cAMP level raises in the tumour cell, thereby the lifting of cAMP concentration has the function of anti-curing oncoma in the cell.

CAMP has physiological significance very widely, as and effect kidney cardiovascular to mammal, but its half-life is shorter, and the discovery and the application of the antagonist of adenosine degraded afterwards xanthine, caffeine and theophylline are for the effect of gland battalion commander effect provides one to use new approaches.Research according to 2000 annual Nobel Laureate Kan Deer and Greengard, cAMP required protein phosphorylation in forming the long-term memory process has facilitation with forming in the new memory synapse process, disclosed the later stage that long time-histories explicit memory strengthens, by the adjusting of cAMP and PKA, dopamine can activate this memory nerve pathway.Bank Dare and then discovery, the long time space memory impairment of mouse can improve by adjusting cAMP.This shows the nerve signal transmission channels activity that cAMP not only can strengthen having failed, also can stop neure damage, even rebuilds those cynapses that lacked connections.

In short, CAMP has following effect to nervous system: (1) antianxiety and sedative-hypnotic effect.The release of adenosine receptor antagonists methyl xanthine endogenous adenosine capable of blocking strengthens brain awakening degree, improves cognitive function.(2) activate the release that to regulate neurotransmitter behind the corresponding acceptor, cause the hyperpolarization of nerve cell, reduce neuronic excitability, thereby suppress neuronic conduction, reduced release and the neural toxic and side effect and the antiepileptic action of excitatory amino acid.(3) neuron there is protective effect.In nervous system, adenosine both can be the steady-state adjustment agent, can serve as neuroregulator again.It should be noted, slightly stress situation under the steady-state adjustment effect of adenosine be advantage, may cover up its nerve regulation effect.(4) the dopaminergic nerve system there is material impact.In the extrapyramidal system motor function was regulated, the basal ganglion dopaminergic neuron played an important role.Normal locomotor activity is regulated and is derived from direct activation and suppresses balance between the corpus straitum DA path indirectly.Directly act on the DA neuron that contains GABA, SP and strong non-peptide from corpus straitum, eliminate by the GABA intrerneuron and suppress or excited up thalamus-cortex glutamic acid serotonergic neuron.Indirectly-acting then contains the DA serotonergic neuron of GABA and enkephalins from corpus straitum, by activation pars reticulata GABA neuron, thereby suppress thalamus-cortex uplink.In addition, CAMP may influence maincenter and pain sensation conduction on every side, participates in the pain process.

The degraded of cAMP is subjected to the restriction of adenyl cyclase.Therefore, promote cAMP activity in the body if desired, then can realize by the activity that suppresses adenyl cyclase.Adenylate cyclase activity can be suppressed by the fast cry of certain animals of methyl yellow, salicylic acid tea calcium alkali and caffeine.

5, the DA factor (dopamine):

The DA factor is that a kind of usefulness is helped the biochemical that the nerve conduction cell transmits pulse signal, is responsible for regulation and control lust, sensation, motion notice and consciousness activity in central nervous system, and with excitement and happy information transmission.Though limit to but be very single-minded in the brain district that it is arranged, and special physiological function is all arranged.Be lower than 5/1000000ths though can secrete the dopaminergic nerve cell sum of the DA factor in the human brain, the DA factor is very important a kind of and relevant classical neurotransmitters such as memory, notice, mood.The DA factor is a base-material with tyrosine, in human brain as a kind of crucial neurotransmitter in hypothalamus and the pituitary gland, its biosynthesis in hippocampus black substance dopaminergic nerve cell, and being stored in the neuron membrane.

Studies show that, the DA factor mainly is positioned at tubercle-funnel position of black substance-corpus straitum, mesolimbic system in the brain central nervous system, concentration is subjected to the influence of individual spirit factor and the strong and weak degree of outside stimulus in its brains, exists aixs cylinder contact and interaction between the GnRH of nerve endings and the DA factor.The DA factor mainly is present in the cerebral hippocampus body, and also there is a small amount of distribution temporal lobe and marginal portion.DAT is that cocaine produces the target site that spiritual floaty euphoria and dependence and amphetamine excitation energy produce similar psychotic symptoms.Cocaine is the retarding agent of DAT, and amphetamine then is to promote the release of dopaminergic neuron DA and the important chemical substance of blocking-up DA reuptake.The major avenues of approach of release of DA nerve synapse and running is as follows:

1. black substance-corpus straitum path belongs to extrapyramidal system, with coordinated movement of various economic factors function.When appearring in this path, functional disorder can cause Parkinson's disease (PD).Its Clinical Processing method is to replenish DA or use the DA receptor stimulating agent; And dopamine is hyperfunction in black substance-corpus straitum path, then can cause ADD.

2. midbrain-limbic system path is mainly regulated mood, and its function and mood, emotion, learning and memory are relevant.

3. temporal lobe path before midbrain-cortex, main participation in learning memory and cognitive, its function with spiritual, the rational faculty is relevant with logic; It also is the positive and negative symptoms action site of schizophrenia.The characteristics of its positive symptom are exaggerative normal function such as vain hope, illusion, the disturbance of emotion etc.; And the characteristics of negative symptoms are to weaken normal function, reduce the ability of identification things, as sensation, understanding, reasoning and vitality atrophy etc.

4. tubercle-funnel path is responsible for prehypophyseal endocrine function.Generally speaking, the DA factor is that a kind of usefulness is helped the biochemical that the nerve conduction cell transmits pulse signal, is responsible for regulation and control lust, sensation, motion notice and consciousness activity in central nervous system, and with excitement and happy information transmission.

Studies show that, the frontal lobe part is as reason and higher level thinking activities zone, if the DA contents level is on the low side, brain can produce and interrupt incoherent state of mind, the mood fluctuation, and reason is out of control, can produce passiveness and feeling of despair without reason, also be easy to cause the logic entanglement, remember badly, even simple mental arithmetic all can the occurrence count obstacle.If the limbic system dopamine concentration is too high, then can cause the suspicious frame of mind, sometimes even can produce vain hope, it is unsociable and eccentric then to seem on the personality, is reluctant to exchange with other people.

Generally speaking, when the nigral dopaminergic neuron unit of the brain endocrine DA factor is partially damaged or because of movable a large amount of the consumption so that its brains DA factor concentration when reducing of long-time learning and memory, just can causes memory and reaction speed decline, motion and cognitive ability impaired.Thereby in diet, suitably replenish the DA factor and biosynthetic precursor substance and cell nutrient solution, so that these materials penetrate blood brain barrier and enter in the nervous system under the help of some bioactivator, make hippocampus black substance dopaminergic nerve cell obtain nourishing, thereby effectively improve cognitive activities and motor functions such as brain memory, study, spontaneous exploratory behavior.

As a kind of brain healthy drink that improves memory and study notice, the contained DA factor of this product and precursor substance thereof are to make joyful, the positive psychology of people's mood and dispel the hot-tempered main functional component in unhealthy emotion aspect such as strongly fragrant.Though the precursor substance tyrosine of human brain biosynthesis DA is nonessential amino acid, the precursor substance phenylalanine of synthetic hydroxyphenylaminopropionic acid is the necessary amino acid that a kind of human body can not synthesize in vain in the organism, so need replenish from food.Discover that levodopa and dopamine exist only in a few natural plants such as banana, Huai Shan, purslane and spunyarn vine.

6, macro-and microelement

Show that according to the study at present known element kind surplus in the of 60 nearly is wherein higher as the content of elements such as calcium, potassium, sodium, oxygen, carbon in the human body, is referred to as the macroelement in the human body, less as nickel, cobalt, selenium equal size, be lower than 60ppm, so be referred to as trace element.Below several the listed anti-inflammatory most important also modal elemental species in the tea that nourishes heart, all be trace or the macroelement that human body must replenish from diet.

(1) ferro element: iron is to the present many aspects of the menu of human body, and iron participates in the transportation and the storage of oxygen.Hemoglobin in the red blood cell is the carrier of transportation oxygen; Iron is the constituent of hemoglobin, combines with oxygen and is transported to each part of health, breathes oxidation for people, and so that energy to be provided, digest food obtains nutrition; Synthetic and the activity of iron and some metalloenzyme is closely related, is the catalyst of life movement.Iron participates in cytochromes, cytochrome oxidase, peroxidase and catalatic synthetic, undertakes electronics transmission and oxidation-reduction process, removes the poisonous substance that tissue metabolism produces.Now known iron and acetyl coenzyme A, succinate dehydrogenase, xanthine oxidase, cytochrome C-reductase etc. is active closely related.And these enzymes all have important physical and biochemical function.Discover that ferro element lacks or excessive meeting causes following dysfunction: 1. iron deficiency causes the brain tissue energy metabolism impairment in human body; 2. iron deficiency causes phenylalanine and catecholamine metabolism unusual.Catecholamine is in its catabolic process, and monoamine oxidase is a key enzyme, and this enzyme to be iron rely on enzyme, its activity depends on sufficient iron in the body, this enzymatic activity descends during iron deficiency, catecholamine metabolism is unusual, thus generation behavior, disturbance of intelligence; 3. iron deficiency makes dopamine receptor function reduction in the brain, the generation behavior and the disturbance of emotion; 4. acetylcholine is and the closest neurotransmitter of learning and memory relation, and iron deficiency can cause cerebral hippocampus district acetyl choline content to descend, thereby influences human brain memory function and intelligence development; Iron deficiency needs iron when 5. DNA is synthetic, so also may damage the formation of neuronic growth and myelin.Normal person's physical efficiency contains adult 3-5g, and infants includes 500mg.

(2) zinc element: zinc is one of trace element of needed by human, is the maximum trace element of content in the brain, is that to keep the brain normal function necessary.Human nerve's cerebration is regulated by various mediators, and many mediators are relevant with zinc; 120 plurality of enzymes such as glutamte dehydrogenase, glutamate decarboxylase all contain the zinc element in the body, synthetic and the metabolism of these enzymes participation protein and DNA, RNA polymerase, many biochemical functions in the body are played an important role and promote brain cell development perfect, are that human intelligence is grown the essential material of institute.As trace element important in the human body is the composition of hundreds of enzyme in the body, composition and activator, and major function: catalysis human body biochemical reaction activates various zymoproteins and participates in the synthetic promotion activation of albumen metabolism.Scarce zinc can cause: 1, amblygeustia, and the tongue taste bud blocks; 2, the different food of partial eclipse is as cinder, earth, nail, wall skin etc.; 3, nanism; 4, wound is difficult for healing; 5, secondary sex characters hypoplasia; 6, woman's menstruation is not risen or tide back apolipsis; 7, influence sperm motility and cause infertility; In addition, scarce zinc can make zinc enzyme reduce as the activity of the super oxygen dismutase (SOD) of removing free radical, thereby hinders the removing of the synthetic and interior free yl of nucleic acid and protein, causes the interior multiple metabolic disorder of body; Also can cause glutamic acid in the brain (excitatory transmitter in a kind of main brain) concentration to reduce.

(3) manganese element: manganese is one of trace element of needed by human.The manganese that human body absorbed is absorbed in enteron aisle, mainly is distributed in muscle, kidney and the brain.Manganese is the composition of plurality of enzymes in the body, the brain endocrine of neurotransmitters such as dopamine and acetylcholine and the synthetic participation that just needs manganese ion.Manganese also plays an important role in cellular metabolism.Manganese deficiency can cause hypophrenia, even brings out epilepsy and schizophrenia.The maximum harm of manganese deficiency is to make brain can't bring into play its normal function.

(4) molybdenum element: molybdenum is the trace element of needed by human.The molybdenum that human body absorbs from food is distributed in each internal organs of whole body through stomach and little intestinal absorption.Molybdenum is the activator of some enzymes, is again the constituent of some enzyme.When molybdenum lacked, energy i (in vivo) metabolic process generation obstacle can cause the myocardial anoxia necrosis.Scarce molybdenum can cause the xanthine oxidase vigor in the liver to reduce, and uric acid excretion reduces, and forms kidney stone and urethral calculus.Molybdenum also participates in the metabolism of iron, and scarce molybdenum can cause iron deficiency, and iron deficiency can cause baby's brain cell number to be reduced or hypofunction, influences intelligence development, and can cause hypoferric anemia.Intelligence and behavior also show as passionnate, and be capricious, absent minded, and surrounding is indifferent to, slow in reacting etc.

(5) copper: copper is micro elements needed by human, is present in the red blood cell, and liver and central nervous system concentration are higher.The formation of kind of important enzyme surplus in the of 30 in the copper participation body, copper enzyme is relevant with the redox reaction in the human body mostly, and it has important function in the formation of hemoglobin, bone and connective tissue; Copper is the formation that participates in myelin in the effect aspect the nerve fiber metabolism, and cytochrome C oxidase, dopamine etc. are copper enzyme in the brain.The normal supply of copper could guarantee the activity of these enzymes, and the function of brain cell could normal performance.Scarce copper is suppressed the activity of copper enzyme, and energetic supersession generation obstacle makes brain function obstacle occur, occurs that mind is indifferent, blunt, the mental retardation of motion and feeblemindedness.

(6) calcium constituent: calcium is the mineral nutrient of needed by human, and all cells all need calcium.Calcium is a kind of metallic element, and argenteous crystallization is easy to chemical combination, is one of human body macroelement, accounts for the 5th.The effect of calcium in human body mainly is: 1, calcium is to form human skeleton, and body support is again the flexible fulcrum of muscle.2, calcium ion (Ca ²⁺) in organism the trigger of many biochemical processes and physiology course, as triggering contraction of muscle, releasing hormone transmits pulse, promotes blood clotting, regulates the rhythm of the heart etc.Ca ²⁺Particularly various senior organisms institute is essential.Studies show that a plurality of systemic-functions such as immunity in calcium and the body, nerve, endocrine, digestion, circulation, motion, reproduction are closely related, calcium ion participates in the overall process of life evolution and life movement.

(7) selenium element: selenium is the indispensable trace element of human body, and selemium nutrition and body's immunity, oxidation resistance, antitumaous effect etc. are closely related.Document shows that in the body antioxidant system, the sweet Guang peptide of GSH-Px and paddy phosphatide peroxidase (PHGSH-Px or HPHGPX) is the selenoenzyme in the human body, can remove free radical and lipid peroxide (LPO).Selenium Supplement can make its activities of antioxidant enzymes strengthen, and removes free radical and LPO ability and strengthens, thereby reach the purpose that delays senility, and for the protection biomembrane special biological significance is arranged.In addition, studies show that selenium is the carrier of calcium, do not have the selenium calcium can not be calm on bone.Selenium is that to keep muscle (comprising heart) healthy necessary.Selenium is also to keeping eyesight, skin and hair healthy that certain effect is arranged.Human selenium deficiency can have multiple performance, and common have: myalgia, myositis, cardiomyoliposis, Keshan disease, and hemolytic anemia, skeleton change (Kaschin-Beck disease), leucocyte sterilizing power and cellular immunity reduction easily cause infection etc.

In addition, except above-mentioned element, drink of the present invention also contains an amount of brain tonic allays excitement institute's essential trace element such as trace elements such as phosphorus, germanium, magnesium, strontium, cobalts.

Claims (3)

1. One kind have anti-inflammatory and mind tranquilizing medicine siddhi can pure natural plant elite health drink, it is characterized in that these health products are is major ingredient by excellent green tea, the biological essence that in addition from the plant that the listed anti-inflammatory of following table is nourished heart, extracts, materials allotments such as the glucose through adding proper proportion, honey and stabilizing agent form again:

   1. main material accounts for 70%.Proportioning is as follows:

   Green tea 8%; Radix Angelicae Sinensis 8%; Stamen nelumbini 8%; American ginseng 8%; Radix rehmanniae recen 8%; Poria cocos 8%; Honeysuckle 5%

   Purple sesame 8%; Asparagus fern 8%; Mountain, Huaihe River 8%; The Radix Astragali 8%; Cordyceps Militaris 5%; Longan 5%; Feverfew 5%

   Glucose, honey, purified water are an amount of

   2. auxilliary material accounts for 30%;
2. 2. according to claim 1 and the described pure natural plant elite of claim 2 health drink, it is characterized in that: comprised the following material that from the listed plant of last table 2, extracts in the contained effective ingredient of these health products with characteristic or function:

   1. gynaecology's anti-inflammatory all substances in the tea formulation that nourish heart must be from extracting through having proved the pure natural plant that has no side effect after people take for a long time over the past thousands of years;

   2. the composition such as triterpenoid saponin, astragalus polyose and the tealeaves bases that contain the raising body immunity that extracts from rare medicinal herbs such as Chinese medicine genseng astragalus, angelica have the material that can keep the excitement of brain appropriateness, can impel brain to keep excitement levels, and extract must guarantee to take for a long time and have no side effect than elevation;

   3. contain higher concentration neurokyme quantity of material, as cAMP, cGMP, ATP, small-molecular peptides, several amino acids, little peptide molecule, protein, glucose;

   4. contain neurotransmitter with the soothing the liver Yu Gongneng of dispelling and the precursor of reprinting trophic factors and neurotransmitter biology and break through the material of blood-brain barrier: GABA, 5-HT, NA, D-sweet mellow wine, alkalescence and neutral amino acid class material;

   5. contain and be degraded rapidly in the antagonism neurotransmitter body or the material of deactivation, as the DAT activity inhibitor that from corydalis tuber, extracts, and the dopamine receptor excitement of extracting from Chinese ephedra, but the yellow fast cry of certain animals of the antagonism cAMP that from tealeaves, the Radix Astragali, genseng, extracts degraded;

   6. contain element potassium, sodium, calcium, iron, manganese, zinc, molybdenum, selenium, germanium, copper, cobalt with the enzymatic activity agent function that makes the deactivation of organism inner virus cell;

   7. contain the vessel dilator that from Chinese medicine safflower, Radix Angelicae Sinensis, the red sage root, extracts, enter nerve center so that the neurotrophy material of larger molecular weight is broken through blood-brain barrier, and remove apoptotic cell remains;

   8. contain the effective ingredient that can promote human body allomeric function and immunity.
3. One kind have anti-inflammatory and mind tranquilizing medicine siddhi can the preparation method of plant health-care beverage, it is characterized in that this beverage made by following method:

   1. choose raw medicinal material: choose listed herbaceous plant finished product in the table from the Chinese herbal medicine operator who appraises and decides registration through national health department, do not clean up, thoroughly remove the impurity sandy soil with purified water by assortment with qualification;

   2. raw medicinal material bulk processing: in order to prevent raw material brown stain takes place in dry run, select the saturated vapor of the 0.1～0.2Mpn enzyme that goes out, held time 5～10 minutes; The material coarse cutting that the raw material behind the enzyme of will going out is dried or dried, the granularity of coarse crushing is 3～6 millimeters;

   3. effective ingredient is slightly carried in the raw medicinal material: the raw medicinal material after will handling drops into extractor, add 10～12 times to the purified water of raw material weight, the purifying electrical conductivity of water is 10～100 μ s/cm, water logging 8～12 hours, be heated to 60～90 degrees centigrade then, stir and extracted 90～120 minutes, the filter residue after the extraction drains juice through squeezer to be mixed with extract;

   4. extracting liquid decoloration and essence are carried: the gained soup was left standstill 8～12 hours, place the Chinese medicine ultrafiltration apparatus carry out essence filter clear solution, the extract after the filtration decolours with active carbon.The decolorizer particle diameter is the granular activated carbon of 0.5～1.0mm, consumption is 1～2% of a total amount of liquid, under 55 degree left and right sides temperature conditions Celsius, stirred 15～30 minutes, leave standstill about 1h, use 150～200 order filter clothes to filter, in de-inking solution, add the diatomite of solution total amount 0.5～1.5% before filtering, filter, till obtaining clear and bright limpid solution while mixing;

   5. must be through the processing process of the medicinal material that processes raw material especially: similar dopamine-receptor stimulant on kind of the material function is arranged in the Chinese ephedra, for extracting these many materials, must earlier ephedra sinica be pulverized, with 65～85 degrees centigrade of emerge in worm water 24～36 hours, when soaking, add a small amount of caustic soda, pH value of water solution is maintained about 13, and filter residue mixes the gained soup with other soup then;

   6. Beverage Service method: the various soups that will be from prescription extract in the raw medicinal material of defined mix to be mixed well, and adds the pure glucose of 5-6% and the high-quality pure honey of 6-8% according to gained soup weight summation;

   A. be deployed into oral liquid: will heat to 85 degrees centigrade from mixed good soup, remain on the sterilization in 3-5 minute of this temperature, add an amount of stabilizing agent, leave standstill 90 minutes, clarification, canned;

   B. be modulated into the powder electuary: according to food-grade particles/powder electuary production process, adopt environment-friendly low-temperature dehydrogenation drying equipment and normal process, reject impurity earlier, clean with the clear water rinsing, put into steamer then and steamed about 3 hours, take out, air-dry, powder essence adds honey, glucose and other extract and stirs to insert in the dehydration equipment after being in harmonious proportion and dehydrate, and powder is pure becomes particle diameter to be no more than 75 microns superfine particles.Divide then in the container of the specified vol of packing into, high-temperature sterilization is also vacuum-packed;

   C. as making pill, then earlier with rejecting impurity such as direct-edible bulk drugs, clean with the clear water rinsing, putting into steamer then steamed about 3 hours, take out air-dry, add honey, glucose and other herbal elite extract stir be in harmonious proportion after, insert in the dehydration equipment and dewater, regrind into ultramicro powder (powder diameter is not more than 75 microns), can make water-honeyed pill or capsule then;

   D. if make syrup, the high-quality honey refining of adding proper proportion in the time of then the decoction that boils should being concentrated to a certain degree.