CN101965396B - 具有丙型肝炎病毒基因的重组痘苗病毒 - Google Patents
具有丙型肝炎病毒基因的重组痘苗病毒 Download PDFInfo
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- CN101965396B CN101965396B CN200980107538XA CN200980107538A CN101965396B CN 101965396 B CN101965396 B CN 101965396B CN 200980107538X A CN200980107538X A CN 200980107538XA CN 200980107538 A CN200980107538 A CN 200980107538A CN 101965396 B CN101965396 B CN 101965396B
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- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/863—Poxviral vectors, e.g. entomopoxvirus
- C12N15/8636—Vaccina virus vectors
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01K67/027—New or modified breeds of vertebrates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0337—Animal models for infectious diseases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Virology (AREA)
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- Biotechnology (AREA)
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- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008057515 | 2008-03-07 | ||
| JP2008-057515 | 2008-03-07 | ||
| JP2008294361A JP5584407B2 (ja) | 2008-03-07 | 2008-11-18 | C型肝炎ウイルス遺伝子を有する組換えワクシニアウイルス |
| JP2008-294361 | 2008-11-18 | ||
| PCT/JP2009/054825 WO2009110644A1 (ja) | 2008-03-07 | 2009-03-06 | C型肝炎ウイルス遺伝子を有する組換えワクシニアウイルス |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101965396A CN101965396A (zh) | 2011-02-02 |
| CN101965396B true CN101965396B (zh) | 2013-08-14 |
Family
ID=41056188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200980107538XA Expired - Fee Related CN101965396B (zh) | 2008-03-07 | 2009-03-06 | 具有丙型肝炎病毒基因的重组痘苗病毒 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9000136B2 (enExample) |
| EP (1) | EP2267120B1 (enExample) |
| JP (1) | JP5584407B2 (enExample) |
| KR (1) | KR101607349B1 (enExample) |
| CN (1) | CN101965396B (enExample) |
| AU (1) | AU2009220401B2 (enExample) |
| CA (1) | CA2717626A1 (enExample) |
| ES (1) | ES2573704T3 (enExample) |
| WO (1) | WO2009110644A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101913553B1 (ko) | 2010-10-15 | 2018-11-05 | 고에키자이단호진 도쿄도 이가쿠 소고겐큐쇼 | 신형 인플루엔자 바이러스 유래 헤마글루티닌 단백질 유전자를 갖는 재조합 백시니아 바이러스 |
| EP2950817B1 (en) * | 2013-01-31 | 2019-08-07 | Portland State University | Immunogenic compositions comprising silicified virus and methods of use |
| WO2014162031A1 (es) * | 2013-04-02 | 2014-10-09 | Consejo Superior De Investigaciones Científicas (Csic) | Vectores recombinantes basados en el virus modificado de ankara (mva) como vacunas preventivas y terapéuticas contra la hepatitis c |
| ES2869575T3 (es) * | 2014-11-11 | 2021-10-25 | Nobelpharma Co Ltd | Composición farmacéutica para el tratamiento y/o la prevención de la hepatitis C |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1942585A (zh) * | 2004-02-20 | 2007-04-04 | 财团法人东京都医学研究机构 | 含人丙型肝炎病毒全长基因组的核酸构建物、核酸构建物转入其中的重组全长病毒基因组复制型细胞和生产丙型肝炎病毒颗粒的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06237773A (ja) | 1992-12-22 | 1994-08-30 | Tonen Corp | ポックスウイルスのa型封入体(ati)プロモーター及び前期プロモーターを含んで成る外来遺伝子発現ベクター |
| JP2003064096A (ja) * | 2001-08-29 | 2003-03-05 | Mitsubishi Kagaku Bio-Clinical Laboratories Inc | C型肝炎ウイルス特異的細胞障害性t細胞認識エピトープ |
| DE10143490C2 (de) * | 2001-09-05 | 2003-12-11 | Gsf Forschungszentrum Umwelt | Rekombinantes MVA mit der Fähigkeit zur Expression von HCV Struktur-Antigenen |
| FR2855758B1 (fr) * | 2003-06-05 | 2005-07-22 | Biomerieux Sa | Composition comprenant la polyproteine ns3/ns4 et le polypeptide ns5b du vhc, vecteurs d'expression incluant les sequences nucleiques correspondantes et leur utilisation en therapeutique |
| EP1710300A4 (en) * | 2003-12-05 | 2007-10-24 | Hokkaido Tech Licensing Office | HIGHLY SAFE POX VACCINE VIRUS AND VACCINIA VIRUS VECTOR |
| JPWO2006013815A1 (ja) * | 2004-08-02 | 2008-05-01 | 財団法人ヒューマンサイエンス振興財団 | HCVウイルスタンパク質をコードするDNAを保有する組換えワクチニアウイルスDIs株、およびその利用 |
| JP4665122B2 (ja) * | 2004-10-08 | 2011-04-06 | 財団法人 東京都医学研究機構 | 組み換えウイルスおよびその用途 |
| JP2008057515A (ja) | 2006-09-04 | 2008-03-13 | Mitsubishi Heavy Ind Ltd | ピックアップセンサの出力電圧判定方法および装置 |
| JP5103058B2 (ja) | 2007-05-28 | 2012-12-19 | 株式会社日立ハイテクノロジーズ | 欠陥観察装置及び欠陥観察方法 |
-
2008
- 2008-11-18 JP JP2008294361A patent/JP5584407B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-06 ES ES09717492.4T patent/ES2573704T3/es active Active
- 2009-03-06 CA CA2717626A patent/CA2717626A1/en not_active Abandoned
- 2009-03-06 KR KR1020107022452A patent/KR101607349B1/ko not_active Expired - Fee Related
- 2009-03-06 WO PCT/JP2009/054825 patent/WO2009110644A1/ja not_active Ceased
- 2009-03-06 US US12/736,079 patent/US9000136B2/en not_active Expired - Fee Related
- 2009-03-06 CN CN200980107538XA patent/CN101965396B/zh not_active Expired - Fee Related
- 2009-03-06 EP EP09717492.4A patent/EP2267120B1/en not_active Not-in-force
- 2009-03-06 AU AU2009220401A patent/AU2009220401B2/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1942585A (zh) * | 2004-02-20 | 2007-04-04 | 财团法人东京都医学研究机构 | 含人丙型肝炎病毒全长基因组的核酸构建物、核酸构建物转入其中的重组全长病毒基因组复制型细胞和生产丙型肝炎病毒颗粒的方法 |
Non-Patent Citations (1)
| Title |
|---|
| AY045702;K.TSUKIYAMA-KOHARA;《NCBI》;20070905;1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009110644A1 (ja) | 2009-09-11 |
| AU2009220401A1 (en) | 2009-09-11 |
| AU2009220401B2 (en) | 2015-07-30 |
| EP2267120A4 (en) | 2012-06-27 |
| EP2267120A1 (en) | 2010-12-29 |
| US9000136B2 (en) | 2015-04-07 |
| CA2717626A1 (en) | 2009-09-11 |
| US20110275139A1 (en) | 2011-11-10 |
| ES2573704T3 (es) | 2016-06-09 |
| CN101965396A (zh) | 2011-02-02 |
| EP2267120B1 (en) | 2016-05-18 |
| KR101607349B1 (ko) | 2016-03-29 |
| KR20100131480A (ko) | 2010-12-15 |
| JP5584407B2 (ja) | 2014-09-03 |
| JP2009232836A (ja) | 2009-10-15 |
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