CN101961010B - Absorbent disinfection dry powder and preparation method thereof - Google Patents
Absorbent disinfection dry powder and preparation method thereof Download PDFInfo
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- CN101961010B CN101961010B CN 201010531259 CN201010531259A CN101961010B CN 101961010 B CN101961010 B CN 101961010B CN 201010531259 CN201010531259 CN 201010531259 CN 201010531259 A CN201010531259 A CN 201010531259A CN 101961010 B CN101961010 B CN 101961010B
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Abstract
The invention discloses absorbent disinfection dry powder and a preparation method thereof. The absorbent disinfection dry powder comprises the following components in percentage by mass: 90 to 99 percent of polyacrylic acid-series macromolecule absorbent resin and 1 to 10 percent of trichloroiminocyanuric acid. The absorbent disinfection dry powder can disinfect an object and remarkable bacteriostatic effect is achieved after the absorbent disinfection dry powder with the disinfectant content of 10 percent, 5 percent and 3 percent absorbs 30 times, 20 times and 10 times of water respectively; and water in the semi-solid/liquid-state object is absorbed and solidified so as to form gel, effectively prevent potential harmful substances or bacteria in the object from dispersing and be convenient for clearing. The absorbent disinfection dry powder has high water absorption speed, high water absorption rate and wide application prospect, is safe and convenient to use and has the average time of 30 seconds from the addition of the absorbent disinfection dry powder to the solidification of the object.
Description
Technical field
The present invention relates to the health and epidemic prevention field, particularly a kind of absorbent disinfection dry powder and preparation method thereof.
Background technology
In recent years, epidemic infectious diseases is becoming increasingly rampant, and has Public Health Emergencies to occur in the time of all over the world, these accidents as can not be in time, effectively reply, usually can cause huge economic loss and society's fear.For this reason, the public health department of national governments studies and defines the emergency preplan of the various Public Health Emergencies of reply one after another, strengthens the supporting dynamics to the research and development of epidemic prevention equipment.Wherein, disinfectant is prevented epidemic after daily sterilization, calamity, is happened suddenly such as SARS, H
1N
1In the great public health event such as influenza, hand-foot-and-mouth disease, brought into play important function.
The characteristics such as desirable disinfectant should possess that fungicidal spectrum is wide, valid density is low, speed of action is fast, soluble in water, non-corrosiveness, noresidue, toxicity are low.In the work of after daily sterilization and calamity, preventing epidemic; often can face the processing problem of the semisolids such as blood, urine, vomitus and excreta, liquid object; but present disinfectant can't be processed semi-solid, liquid dirt fast, effectively, and work has increased difficulty to subsequent treatment.
Summary of the invention
The present invention is directed to the shortcoming that existing disinfectant can't fast carry out disinfection and clear up semi-solid, liquid dirt, a kind of absorbent disinfection dry powder is provided.This absorbent disinfection dry powder bactericidal effect is good, safe, rapid-action, and it is simple, convenient and rapid to process semisolid and liquid dirt.
In order to realize the foregoing invention purpose, the invention provides following technical scheme:
The invention provides a kind of absorbent disinfection dry powder, by percentage to the quality, formed by the polyacrylic hydroscopic high-molecular resin of 90-99% and the sym-closene of 1-10%.
As preferably, by percentage to the quality, absorbent disinfection dry powder provided by the invention is comprised of the polyacrylic hydroscopic high-molecular resin of 95-97% and the sym-closene of 3-5%.
Preferably, by percentage to the quality, absorbent disinfection dry powder provided by the invention is comprised of 95% polyacrylic hydroscopic high-molecular resin and 5% sym-closene.
At present, water-absorbing resin mainly contains the series of products such as polyacrylonitrile, polyacrylic acid, polyacrylamide both at home and abroad, and wherein polyacrylonitrile based water-absorbing resin hydrolysate water absorption rate is high, but complex process, remaining cyano group is poisonous; Polyacrylamide water-absorbing resin salt resistance is high, but water absorption rate is low; The polyacrylic water-absorbing resin is except possessing the key propertys such as high water absorbing capacity, and its raw material is from industrial acrylic acid, and production cost is relatively low, and technique is easier, and constant product quality.
When the processing target thing, consider that the human body fluid major part is acid, the present invention is chosen in pH value＜7 and o'clock still has the polyacrylic hydroscopic high-molecular resin of better soaking effect as water absorbing agent.The polyacrylic hydroscopic high-molecular resin, be a kind of containing-COOH ,-the strongly hydrophilic group such as OH and water-soluble intumescent high molecular polymer with certain degree of cross linking, the polyacrylic water-absorbing resin mainly refers to the terpolymer that acrylic acid, acrylates and crosslinking agent form, or the multiple copolymer of the formation such as acrylic acid and other organic and inorganic things.
Polyacrylic hydroscopic high-molecular resin water absorbent rate is higher, can within a few minutes even a few second, suck the water that reaches hundreds of times of sole masses, have high suction and water retention capacity, be widely used in the every field such as industry, agricultural, health care, coating and people's lives.Although polyacrylic water-absorbing resin water absorption rate is good, salt resistance is poor.
The principal element that affects water-absorbing resin quality and water absorbing properties has the consumption of the consumption of crosslinking agent, acrylic acid degree of neutralization, monomer etc.Crosslinking agent makes water-absorbing resin become the crosslinking net macromolecular structure, and crosslink density can not be too large, can not be too little.The water absorbing capacity of crosslink density and resin is closely related, if dosage of crosslinking agent is less, then resin crosslinks is insufficient, and the resin after the suction becomes half dissolved state; And the increase dosage of crosslinking agent can increase the resin crosslinks degree, but when crosslink density was excessive, the stretching, extension of molecular resin chain can be restricted, fully imbibition, and then soaking effect descends.Preferably select the resin that in water-fast situation, is in the minimum degree of cross linking, just may have high water absorbing properties.Do the water-absorbing resin of crosslinking agent with glycerine, good salt tolerance, water absorption rate is high, and the maximum water absorption rate of gained water absorbing agent can reach 800g/g, absorbs more than 0.9% the sodium chloride solution 80g/g.Need to use in the alkali before the acroleic acid polymerization and a part of hydroxy-acid group, the degree of neutralization general control is at 30-80%.Therefore, as preferably, the present invention amid all these factors can the selective polymerization degree be 1,000,000, degree of neutralization is 60%, adopts glycerine to do the synthetic polyacrylic hydroscopic high-molecular resin of crosslinking agent.In an embodiment of the present invention, the employed degree of polymerization is 1,000,000 polyacrylic hydroscopic high-molecular resin, is provided by TangShan BoYa resin Co., Ltd.Its outward appearance is white uniform powder or particle, the water absorbent rate of distilled water is 300-400g/g, the water absorbent rate of 0.9% sodium chloride solution is 55 ± 3g/g, centrifugal maintenance dose 〉=35g/g, the pressurizing absorption amount 〉=26g/g under the 0.3PSI condition, the Xia Housudu that swirl method is measured is≤50s, the pH value is 5.5-6.5, granularity is 180-600 μ m, standard screen percent of pass 〉=85%, self moisture≤7.0%.
Sym-closene is a kind of chloride high effect disinfectants, by making the bacterium protein sex change, changes membrane permeability, and interferases system Physiology and biochemistry the and affect processes such as DNA is synthetic makes rapidly death of pathogen.The structural formula of sym-closene is as follows:
Sym-closene, molecular formula are C
3Cl
3N
3O
3, molecular weight: 232.41, fusing point: 247-251 ℃, be white crystalline powder or granular solids, have strong chlorine pungent taste, contain available chlorine more than 90%, the solvability in the time of 25 ℃ in the water is 1.2%, meets acid or alkali and easily decomposes.It is a kind of extremely strong oxidant and chlorinating agent, has efficient, wide spectrum, safer disinfective action, and bacterium, virus, fungi, gemma etc. are had killing action, and coccidian oocyst is also had certain killing effect.
Sym-closene carries out disinfection by producing hypochlorous acid, and hypochlorous acid is the most important base substance of destroy microorganisms.Sterilization mechanism comprises effect and the chlorination of hypochlorous oxidation, newborn oxygen.Hypochlorous oxidation is the topmost sterilization mechanism of chlorine-containing disinfectant.Hypochlorous acid not only can be had an effect with microorganism wall, and because its molecule is little, neutral so easily invade in the microbial cell and protein generation oxidation or destruction phosphate dehydrogenase, makes the glycometabolism imbalance and death; Can also produce nascent oxygen when hypochlorous acid decomposes, the hypochlorous acid disinfective action may with the nascent oxygen relation that combined with microbial cell magma; Chlorine-containing disinfectant also can play bactericidal action by chlorine, and chlorine changes cell wall, permeability of cell membrane; Chlorine can be combined with epicyte protein, forms nitrogen-chlorine compound; Chlorine has oxidation to some important enzyme of bacterium, thereby interference cell is metabolic.Because the polyacrylic hydroscopic high-molecular resin is responsive to salt, so the present invention selects sym-closene as disinfectant.
The present invention also provides the preparation method of described absorbent disinfection dry powder, comprises following steps:
Step 1: supply raw materials: by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 90-99%, and sym-closene accounts for 1-10%;
Step 2: described polyacrylic hydroscopic high-molecular resin and sym-closene are passed through respectively 40 mesh sieves;
Step 3: behind described polyacrylic hydroscopic high-molecular resin and sym-closene mixed grinding, cross 60 mesh sieves.
Wherein, consider the water imbibition of absorbent disinfection dry powder and preparation technology's operability, in preparation technology, polyacrylic hydroscopic high-molecular resin and sym-closene are screened by 40 mesh sieves respectively; Cross mixed grinding behind 40 mesh sieves, again the mixture of above-mentioned polyacrylic hydroscopic high-molecular resin and sym-closene is crossed 60 mesh sieves, namely make absorbent disinfection dry powder provided by the invention.
As preferably, when preparation absorbent disinfection dry powder provided by the invention, raw material by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 95-97%, sym-closene accounts for 3-5%.
As preferably, when preparation absorbent disinfection dry powder provided by the invention, raw material by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 95%, sym-closene accounts for 5%.
The present invention adds the polyacrylic hydroscopic high-molecular resin in the disinfectant sym-closene, check its absorbent disinfection effect.Result of the test shows, disinfectant content is that 10%, 5%, 3% absorbent disinfection dry powder absorbs water respectively after 30 times, 20 times and 10 times, and antibacterial ring is obvious, the fungistatic effect highly significant.
The result of soaking effect shows that the absorption speed of absorbent disinfection dry powder is fast, and the time average that is cured as gel from adding absorbent disinfection dry powder to target handled thing is 30s; Water absorbent rate is high, and average out to 45-63g/g, maximum water absorbent rate are 63 times.Soaking effect is subjected to the pH value of target handled thing, the impact of absorbent disinfection dry powder addition, be in the 3-9 scope in the pH of target handled thing value, the water absorbent rate of absorbent disinfection dry powder reaches 44.1-48.6 doubly, add excessive absorbent disinfection dry powder and still can make the excessively low solution generation water absorbent gel of pH value, but be subjected to hardly the impact of absorbent time.
Comprehensive above-mentioned result of the test, after absorbent disinfection dry powder provided by the invention makes an addition to semisolid, liquid target handled thing surface, in sterilizing, moisture absorption in the target handled thing can be solidified, effectively prevent harmful substance potential in the target handled thing or proliferation of germs, be convenient to cleaning.Therefore can process the semisolid, the liquid dirt that run in the epidemic prevention process after daily sterilization, the calamity, such as vomitus, blood, urine etc., Disinfection Effect is remarkable, has reduced the difficulty of follow-up cleaning work, is with a wide range of applications.
Description of drawings
Fig. 1 shows that 0.9% sodium-chloride water solution of different pH values is on the impact of the water absorbent rate of absorbent disinfection dry powder.
Fig. 2 shows that absorbent time is on the impact of absorbent disinfection dry powder water absorbent rate when the pH value is 1.
Embodiment
The invention discloses a kind of absorbent disinfection dry powder and preparation technology thereof, those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are deemed to be included in the present invention.Method of the present invention and application are described by preferred embodiment, the related personnel obviously can change or suitably change and combination methods and applications as herein described within not breaking away from content of the present invention, spirit and scope, realizes and use the technology of the present invention.
Absorbent disinfection dry powder provided by the invention, select in the high effect disinfectants sym-closene that to add the degree of polymerization be 1,000,000 polyacrylic hydroscopic high-molecular resin, semi-solid in the epidemic prevention after daily sterilization, calamity with solving, the liquid dirt is difficult for processing, the easy problem of diffusion of germ.In an embodiment of the present invention, the employed degree of polymerization is 1,000,000 polyacrylic hydroscopic high-molecular resin, is provided by TangShan BoYa resin Co., Ltd.Its outward appearance is white uniform powder or particle, the water absorbent rate of distilled water is 300-400g/g, the water absorbent rate of 0.9% sodium chloride solution is 55 ± 3g/g, centrifugal maintenance dose 〉=35g/g, the pressurizing absorption amount 〉=26g/g under the 0.3PSI condition, the infiltration rate that swirl method is measured is≤50s, the pH value is 5.5-6.5, granularity is 180-600 μ m, standard screen percent of pass 〉=85%, self moisture≤7.0%.
Character by the polyacrylic hydroscopic high-molecular resin determines that its water absorbing properties mainly is subject to the pH value of target handled thing, the impact of salinity.Human body fluid oozes salting liquid for waiting, therefore use physiological saline namely 0.9% sodium-chloride water solution investigated as the salt disturbing factor; The scope of pH value in the human body fluid minimumly in the stomach reaches 1, can reach 8.5 in the bile, so range of choice is that the pH value of 1-9 is investigated the target handled thing of different pH values to the impact of absorbent disinfection dry powder water absorbent rate.
Utilizing sodium chloride and distilled water compound concentration is 0.9% sodium-chloride water solution, with hydrochloric acid or sodium hydrate regulator solution pH value, obtaining pH value is respectively: 1,2,3,5,7,9 concentration is 0.9% sodium-chloride water solution, utilizes the variation of mentioned solution detection absorbent disinfection dry powder water absorbent rate in 0.9% sodium-chloride water solution of different pH values; Considering that human gastric juice pH value can reduce reaches 1, therefore, further investigates when pH=1, and the absorbent time of absorbent disinfection dry powder is on the impact of water absorbent rate; For the extreme case of pH=1, by adding excessive absorbent disinfection dry powder, investigate the absorbent disinfection dry powder addition to the impact of water absorbent rate; Consider in the actual conditions, when absorbent disinfection dry powder has potential contagiosity body fluid for the treatment of blood, urine, vomitus and excreta etc., blood and urine contain large quantity of moisture, absorbent disinfection dry powder absorbs it and changes into the solid-state cleaning that is easy to, but absorbent disinfection dry powder is when the semi-solid material such as processing vomitus and excreta, the thickness of semi-solid material may exert an influence to the absorbent disinfection dry powder soaking effect, therefore, investigates the milled congee of different denseness to the impact of water absorbent rate; Consider that ground is covered with the situation of the fabrics such as carpet, we select a white towel simulate fabric, milled congee is poured over simulates vomitus on the towel, investigate dirt surface texturisation of living in to the impact of water absorbent rate; Utilize again the actual sample of blood, urine and vomitus, the water absorbent rate of absorbent disinfection dry powder is carried out practice examining.
The computing formula of water absorbent rate:
In the formula: v: water absorbent rate; m
0: absorbent disinfection dry powder quality (g); m
1: filter blank sample nylon net bag quality (g); m
2: absorbent disinfection dry powder and nylon net bag gross mass (g) after the suction.
The result of the soaking effect of absorbent disinfection dry powder provided by the invention shows that the absorption speed of absorbent disinfection dry powder is fast, and the time average that is cured as gel from adding absorbent disinfection dry powder to target handled thing is 30s; Water absorbent rate is high, and average out to 45-63g/g, maximum water absorbent rate are 63 times.Soaking effect is subjected to the impact of pH value, absorbent disinfection dry powder addition,, adds excessive absorbent disinfection dry powder still can make the lower solution generation water absorbent gel of pH value for water absorbent rate in the 3-9 scope reaches 44.1-48.6 doubly in the pH value; But be subjected to hardly the impact of absorbent time.
In the check soaking effect, Disinfection Effect to absorbent disinfection dry powder is tested, need to carry out Germicidal test: according to the requirement of 2002 editions disinfection technology standards, when the Disinfection Effect of general article surface and fabric is tested, with staphylococcus aureus ATCC 6538, Latin is called Staphylococcus aureus, as the representative of pyococcus in the bacterial propagule; Escherichia coli 8099, Latin is called Escherichia coli, as the representative of enteron aisle bacterium in the bacterial propagule.
Escherichia coli, Latin is called Escherichia coli, is under the jurisdiction of Escherichia, is that Escherich found in 1885, within the quite a long time, is taken as the part of normal the gut flora always, thinks non-pathogenic bacteria.Until 20 middle of century recognize that just the Escherichia coli of some special serotypes have pathogenicity to humans and animals, especially to baby and cub, fowl, often cause severe diarrhea and septicemia.
Staphylococcus aureus, Latin is called Staphyloccocus aureus Rosenbach, is under the jurisdiction of staphylococcus, is human a kind of important pathogen, can cause multiple severe infections.Staphylococcus aureus is modal pathogen in the human suppurative infection, can cause local suppurative infection, also can cause pneumonia, pseudomembranous enteritis, pericarditis etc., even the general infection such as septicemia, pyemia.
Absorbent disinfection dry powder provided by the invention shows the fungistatic effect result of Escherichia coli and staphylococcus aureus, disinfectant content is that 10%, 5%, 3% absorbent disinfection dry powder absorbs water respectively after 30 times, 20 times and 10 times, antibacterial ring is obvious, and fungistatic effect is remarkable.
Below in conjunction with embodiment, further set forth the present invention:
The preparation of embodiment 1 absorbent disinfection dry powder
The degree of polymerization that is provided by TangShan BoYa resin Co., Ltd is that 1,000,000 polyacrylic hydroscopic high-molecular resin character is as shown in table 1, accurately take by weighing polyacrylic hydroscopic high-molecular resin 95g, the 5g sym-closene, cross 40 mesh sieves after the drying respectively, grind after mixing, cross 60 mesh sieves, make the absorbent disinfection dry powder of 100g independent packaging.
The physical and chemical index of table 1 polyacrylic hydroscopic high-molecular resin
The preparation of embodiment 2 absorbent disinfection dry powders
The degree of polymerization that accurately taking by weighing 90g is provided by TangShan BoYa resin Co., Ltd is 1,000,000 polyacrylic hydroscopic high-molecular resin, the 10g sym-closene, dry rear 40 mesh sieves of crossing grind after mixing respectively, cross 60 mesh sieves, make the absorbent disinfection dry powder of 100g independent packaging.
The preparation of embodiment 3 absorbent disinfection dry powders
The degree of polymerization that accurately taking by weighing 97g is provided by TangShan BoYa resin Co., Ltd is 1,000,000 polyacrylic hydroscopic high-molecular resin, the 3g sym-closene, dry rear 40 mesh sieves of crossing grind after mixing respectively, cross 60 mesh sieves, make the absorbent disinfection dry powder of 100g independent packaging.
The preparation of embodiment 4 absorbent disinfection dry powders
The degree of polymerization that accurately taking by weighing 99g is provided by TangShan BoYa resin Co., Ltd is 1,000,000 polyacrylic hydroscopic high-molecular resin, the 1g sym-closene, dry rear 40 mesh sieves of crossing grind after mixing respectively, cross 60 mesh sieves, make the absorbent disinfection dry powder of 100g independent packaging.
The preparation of embodiment 5 absorbent disinfection dry powders
The degree of polymerization that accurately taking by weighing 93g is provided by TangShan BoYa resin Co., Ltd is 1,000,000 polyacrylic hydroscopic high-molecular resin, the 7g sym-closene, dry rear 40 mesh sieves of crossing grind after mixing respectively, cross 60 mesh sieves, make the absorbent disinfection dry powder of 100g independent packaging.
The pH value of embodiment 6 objects and salinity are on the impact of absorbent disinfection dry powder soaking effect
Prepare 6 parts of concentration and be 0.9% sodium-chloride water solution, take by weighing respectively 0.09gNaCl, measure 10mL distilled water, place 250mL conical flask mixing for subsequent use.Regulate each pH with the hydrochloric acid of 1mol/L and the sodium hydroxide of 1mol/L, so that the pH value of 6 part 0.9% sodium-chloride water solution is respectively: 1,2,3,5,7,9.In above-mentioned 6 part 0.9% sodium-chloride water solution, add respectively the absorbent disinfection dry powder that provides among the 1g embodiment 1.Investigate the soaking effect of absorbent disinfection dry powder in different pH value.Result such as table 2, shown in Figure 1.
The pH value of table 2 solution is on the impact of water absorbent rate
| The pH value | Water absorbent rate (g/g) |
| 1 | 12 |
| 2 | 10.2 |
| 3 | 44.1 |
| 5 | 48.6 |
| 7 | 48.5 |
| 9 | 47 |
Test finds that absorbent disinfection dry powder reaches 44.1-48.6 times in the pH value for water absorbent rate in the 3-9 scope, and when the pH value was reduced to 2, the water absorbent rate of absorbent disinfection dry powder was dropped rapidly to 10.2 times; When the pH value was reduced to 1, the water absorbent rate of absorbent disinfection dry powder was 12 times.As seen, the water absorbent rate of absorbent disinfection dry powder is affected by the pH value.
Embodiment 7 is under identical pH value and salinity, and absorbent time is on the impact of absorbent disinfection dry powder soaking effect
In the sodium-chloride water solution of the 10mL 0.9% of pH=1, add the absorbent disinfection dry powder that 1g embodiment 1 provides, use stopwatch writing time, the absorbent time of investigation absorbent disinfection dry powder is on the impact of water absorbent rate.Result such as table 3, shown in Figure 2.
Table 3 is under the same solution condition, and absorbent time is on the impact of water absorbent rate
| Absorbent time (min) | Water absorbent rate (g/g) |
| 3 | 10.2 |
| 5 | 11.3 |
| 10 | 9.7 |
| 15 | 8.6 |
| 30 | 9.6 |
| 60 | 12 |
The result shows, when absorbent disinfection dry powder adds in the solution behind the 3min, water absorbent rate has reached 10.2g/g, and the onset of visible absorbent disinfection dry powder provided by the invention is rapid; Behind the suction 5min, water absorbent rate reaches 11.3g/g, prolongs in time again, and the water absorbent rate of absorbent disinfection dry powder is without obvious increase, even when 10-30min, water absorbent rate is reduced to 8.6-9.7g/g, even absorbent time prolongs, also can't improve its water absorbent rate.When absorbent time reached 60min, water absorbent rate increased to 12g/g, and the water absorbent rate during with 5min is compared does not have significant difference.As seen, absorbent disinfection dry powder water absorbent rate when low pH value descends, but affected by absorbent time.
Embodiment 8 is under identical pH value and salinity, and addition is on the impact of absorbent disinfection dry powder soaking effect
In the sodium-chloride water solution of the 10mL 0.9% of pH=1, add the absorbent disinfection dry powder 23.4g that excessive embodiment 1 provides, investigate the addition of absorbent disinfection dry powder to the impact of water absorbent rate.
Test is found, adds excessive absorbent disinfection dry powder, still liquid absorption can be formed gel.As seen, absorbent disinfection dry powder water absorbent rate when low pH value descends, but after adding excessive absorbent disinfection dry powder, still moisture-curing in the solution can be formed gel.
The thickness of embodiment 9 objects is on the impact of absorbent disinfection dry powder soaking effect
When object thickness is 5mm:
Millet and the water ratio according to 1: 20 is mixed in culture dish, and making thickness is the milled congee simulation test sample of 5mm, then adds the absorbent disinfection dry powder that 5g embodiment 1 provides, and is spread across the milled congee surface, places 2-3min, observed result.Investigate object thickness to the impact of the water absorbent gel effect of absorbent disinfection dry powder.
Test finds, absorbent disinfection dry powder is spread across the milled congee surface after, upper strata moisture is rapidly absorbed and is solidified into gel; Behind the 2-3min to be placed, scratch the top layer, find that the moisture in lower floor's milled congee also is cured, the milled congee after the curing still is fixed on the culture dish bottom in the culture dish that tilts, do not flow.As seen, when the 5mm, do not affect the performance of the water absorbent gel of absorbent disinfection dry powder for semi-solid object thickness.
When object thickness is 15mm:
Millet and the water ratio according to 1: 10 is mixed in culture dish, and making thickness is the milled congee simulation test sample of 15mm, then adds the absorbent disinfection dry powder that 10g embodiment 1 provides, and is spread across the milled congee surface, places 2-3min, observed result.Investigate object thickness to the impact of the water absorbent gel effect of absorbent disinfection dry powder.
Test finds, absorbent disinfection dry powder is spread across the milled congee surface after, upper strata moisture is rapidly absorbed curing; Behind the 2-3min to be placed, scratch the top layer, find that the moisture in lower floor's milled congee also is cured.As seen, when the 15mm, do not affect the performance of the water absorbent gel of absorbent disinfection dry powder for semi-solid object thickness.
The object simulating situation is investigated object thickness to the impact of soaking effect
Select a white towel simulation carpet, the milled congee among the embodiment 5 is poured over simulates vomitus on the towel, then add and spill the absorbent disinfection dry powder 5g that embodiment 1 provides, observed result.
Test finds that after white towel was toppled over milled congee, towelling coverlet soaked, and milled congee is bonded on the towel not easy-clear; Milled congee dipping position add spill absorbent disinfection dry powder after, moisture is cured into rapidly gel in the milled congee, the semisolid after solidifying can be simulated the vomitus milled congee with scuppit and scoop up, and remains a small amount of residue, available scuppit picks up removing; White towel after the processing, only stay water stain on a small quantity, without solid residue.
Situation in kind in the embodiment 10 simulated aircraft cabins, the soaking effect of absorbent disinfection dry powder
When analogies are clinical vomitus:
Select a white towel simulation carpet, a small amount of clinical vomitus is positioned on the towel, add on the vomitus surface and spill the absorbent disinfection dry powder that embodiment 1 provides, addition is as the criterion to cover clinical vomitus.Behind the 2-3min, observed result.
Test finds that after white towel was toppled over clinical vomitus, towelling coverlet soaked, and clinical vomitus is bonded on the towel not easy-clear; Clinical vomitus dipping position add spill absorbent disinfection dry powder after, the moisture in the clinical vomitus is cured into rapidly gel, the semi-solid clinical vomitus after the curing can be scooped up with scuppit, remains a small amount of residue, available scuppit picks up removing; White towel after the processing, only stay water stain on a small quantity, without solid residue.As seen, absorbent disinfection dry powder possesses the performance with the vomitus water absorbent gel.
When analogies are clinical blood:
Select a white plastic cloth simulation accomodation ground, a small amount of clinical blood is positioned on the Polypropylence Sheet, add on the clinical blood surface and spill the absorbent disinfection dry powder that embodiment 1 provides, addition is as the criterion to cover clinical blood.Behind the 2-3min, observed result.
Test finds that after white plastic cloth was toppled over clinical blood, Polypropylence Sheet was soaked, and clinical blood is bonded on the Polypropylence Sheet not easy-clear; Clinical blood dipping position add spill absorbent disinfection dry powder after, the moisture in the clinical blood is cured into rapidly gel, the semi-solid clinical blood after the curing can be scooped up with scuppit, remains a small amount of residue, available scuppit picks up removing; White plastic cloth after the processing only stays a small amount of bloodstain, without solid residue.As seen, absorbent disinfection dry powder possesses the performance with the blood water absorbent gel.
When analogies are clinical urine:
Select a white plastic cloth simulation accomodation ground, a small amount of clinical urine is positioned on the Polypropylence Sheet, add on clinical urine surface and spill the absorbent disinfection dry powder that embodiment 1 provides, addition is as the criterion to cover clinical urine.Behind the 2-3min, observed result.
Test finds that after white plastic cloth was toppled over Clinical Urinary liquid, Polypropylence Sheet was soaked, and clinical urine is bonded on the Polypropylence Sheet not easy-clear; Clinical urine dipping portion position add spill absorbent disinfection dry powder after, the moisture in the clinical urine is cured into rapidly gel, the semi-solid clinical urine after solidifying can be scooped up with scuppit, remains a small amount of residue, available scuppit picks up removing; White plastic cloth after the processing only stays a small amount of urine stain, without solid residue.As seen, absorbent disinfection dry powder possesses the performance with the urine water absorbent gel.
The soaking effect of embodiment 11 absorbent disinfection dry powders
Set up the evaluation method of measuring water absorbing properties
Accurately take by weighing the absorbent disinfection dry powder that 1.0000g embodiment 1 provides, above-mentioned absorbent disinfection dry powder is added in the 200mL distilled water, place 60min; The Nylon Bag that adopts 4 layers of nylon sock to make filters dry powder and the solution after the above-mentioned suction, no longer includes liquid to the Nylon Bag to ooze, and keeps 5min; Take by weighing absorbent disinfection dry powder after the above-mentioned suction and the gross mass of Nylon Bag.The record result.Filtrate and distilled water adopt optical colorimetry relatively, there was no significant difference.The absorbent disinfection dry powder of staying after absorbing water in the nylon net bag presents solid-state colorless transparent gel.
The result shows, behind the mesh bag that 200mL distilled water is made through 4 layers of nylon sock, the mesh bag quality increases to 13.0g by 11.9g, and the mesh bag 1.1g that only increases weight is little on the impact of water absorbent rate measurement result, can ignore.Therefore, in measuring the test of absorbent disinfection dry powder water absorbent rate, the mesh bag that 4 layers of nylon sock are made can be used as the apparatus that filters moisture, allows moisture to pass through, and the gel that forms after the resin suction is stayed in the bag, and can not impact result of the test.The method of above-mentioned detection water absorbing properties has operability, and obtained result has confidence level.
Soaking effect is estimated:
The absorption speed of absorbent disinfection dry powder is fast, and the time average that is cured as gel from adding absorbent disinfection dry powder to target handled thing is 30s; Water absorbent rate is high, and average out to 45-63g/g, maximum water absorbent rate are 63 times.
Embodiment 13 Evaluation of Germicidal Efficacies
Experimental group 1: take by weighing polyacrylic hydroscopic high-molecular resin 0.9g, sym-closene 0.1g, routine mixes.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is a processed group, joins respectively in the sterile water of 10mL, 20mL, 30mL, be solidified into gel until absorbing water fully after, respectively get 1g, for subsequent use.
Experimental group 2: take by weighing polyacrylic hydroscopic high-molecular resin 0.95g, sym-closene 0.5g, routine mixes.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is a processed group, joins respectively in the sterile water of 30mL, 20mL, 10mL, be solidified into gel until absorbing water fully after, respectively get 1g, for subsequent use.
Experimental group 3: take by weighing polyacrylic hydroscopic high-molecular resin 0.97g, sym-closene 0.3g, routine mixes.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is a processed group, joins respectively in the sterile water of 30mL, 20mL, 10mL, be solidified into gel until absorbing water fully after, respectively get 1g, for subsequent use.
Experimental group 4: take by weighing polyacrylic hydroscopic high-molecular resin 0.98g, sym-closene 0.2g, routine mixes.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is a processed group, joins respectively in the sterile water of 30mL, 20mL, 10mL, be solidified into gel until absorbing water fully after, respectively get 1g, for subsequent use.
Experimental group 5: take by weighing polyacrylic hydroscopic high-molecular resin 0.99g, sym-closene 0.1g, routine mixes.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is a processed group, joins respectively in the sterile water of 30mL, 20mL, 10mL, be solidified into gel until absorbing water fully after, respectively get 1g, for subsequent use.
Negative control group: take by weighing polyacrylic hydroscopic high-molecular resin 1g.According to the method described above, prepare altogether 12 parts of identical absorbent disinfection dry powders, per 4 parts is 1 processed group, joins respectively in the sterile water of 30mL, 20mL, 10mL, be solidified into gel until absorbing water fully after, it is for subsequent use respectively to get 1g.
Wherein, 4 parts of gel samples in 30 times of suctions in experimental group 1 to 5 and the negative control group, 20 times of suctions, 3 processed group of 10 times of suctions are had an effect with Escherichia coli, staphylococcus aureus respectively, 2 parts is one group, in test parallel control is set, and end product is averaged.Experimental group 1,2,3,4,5, negative control are designated as respectively A, B, C, D, E, F; 10 times of suctions are designated as 1,20 times of suction to be designated as 2,30 times of suctions and to be designated as 3.The test group sees Table 4.
The grouping of table 4 disinfection effect test
The preparation of bacterial suspension: get the freeze-drying lactobacillus pipe of Escherichia coli, staphylococcus aureus, open under sterile working, add adequate nutrition meat soup with capillary syring, soft pressure-vaccum melts bacterial classification and disperses for several times.Get and contain 5.0mL-10.0mL nutrient broth medium test tube, splash into a little bacteria suspension, put 37 ℃ and cultivate 18h.Get the bacteria suspension that 1st generation is cultivated with oese, streak inoculation is cultivated 18h in 37 ℃ on the nutrient agar flat board.Colonies typical in the above-mentioned 2nd generation culture of picking is inoculated in the nutrient agar inclined-plane, in 37 ℃ of cultivation 18h-24h, is the 3rd culture thing.Get the bacterial classification nutrient agar inclined-plane fresh cultured thing cultivation 18h in the 3rd generation, draw the 5.0mL dilution with the 5.0mL suction pipe and add in the slant tube, pressure-vaccum washes lawn repeatedly.Subsequently, with the 5.0mL suction pipe washing lotion is moved in another sterile test tube, mix vibration 20s with motorized agitator, or shake at palm and to strike 80 times, so that bacterial suspension is even, tentatively make 5 * 10
5-5 * 10
6The bacteria suspension of cfu/mL.Be kept in 4 ℃ of refrigerators for subsequent use.
The preparation of nutrient agar plate: the nutrient agar that will dissolve is poured aseptic plate 10mL into, prevents from solidifying, and is drawn on the nutrient agar surface saying that the bacteria suspension of making evenly is coated with platinum loop respectively.
Laying of disinfectant: in experimental group one to five and negative control group, the 1g absorbent disinfection dry powder absorbs respectively the gel of 10 times, 20 times, the 30 times formation behind the sterile water, respectively get again its 1g respectively cloth be placed on the plate central authorities that are coated with bacterium, above-mentioned plate is placed in the incubator, 37 ℃ ± 1 ℃, cultivate 24h, investigate the Disinfection Effect of absorbent disinfection dry powder.Result such as table 5.
The Disinfection Effect of the absorbent disinfection dry powder under the different water absorbent rates of table 5
Data are the mean value of twice test data in the table 5.
According to the Ministry of Public Health's 2002 editions " disinfection technology standard " Disinfection Effects criterion: antibacterial ring＞7mm be judged to be antibacterial effectively, it is invalid that≤7mm then is judged to be, by table 1 result as seen, disinfectant content is that 10%, 5%, 3% absorbent disinfection dry powder absorbs water respectively after 30 times, 20 times and 10 times, antibacterial ring is all greater than 35mm, the fungistatic effect highly significant; Disinfectant content is after 30 times, 20 times and 10 times suctions of absorbent disinfection dry powder of 2%, Escherichia coli also to be had obvious fungistatic effect, and it is not obvious to the fungistatic effect of staphylococcus aureus after 30 times to absorb water; The content of disinfectant is after 10 times of suctions of absorbent disinfection dry powder of 1% Escherichia coli to be had inhibitory action, after 20 times, the 10 times suctions staphylococcus aureus is had significantly bacteriostasis, and the fungistatic effect after all the other water absorbent rates suctions is all not obvious.
The detection of the sterilization inspection body that the Disinfection Effect of absorbent disinfection dry powder has been assert by the Ministry of Public Health, indices meets national standard, and obtains the domestic disinfectant health license approval of Ministry of Health of the People's Republic of China.Authentication code: defend No. the 0027th, the word (2001) of disappearing; Approved date: on August 12nd, 2008.
Embodiment 14 safety evaluatios
Safety evaluatio to people, livestock: absorbent disinfection dry powder provided by the invention is to be that 95% hydroscopic high-molecular resin and 5% sym-closene are mixed by mass fraction.Hydroscopic high-molecular resin is polymerized by the acrylic acid height, and is nontoxic, harmless, water insoluble, be dissolved in any solvent hardly.Be widely used at present the many-sides such as sanitary napkin, baby paper diaper, agricultural gardening water conservation, medicine moisturizing, drying, thus can inference, hydroscopic high-molecular resin is safe and reliable to people, livestock.Another composition of absorbent disinfection dry powder is sym-closene, is a kind of organic chlorine-containing disinfectant, and the hydrolysis end product is ammonia, water and carbonic acid gas after using.The FDA of Food and Drug Administration and this product of the equal approved of the EPA of American National Bureau for Environmental Protection are used for the disinfection of agricultural, aquatic products, food and drinking water.
Safety evaluatio to metallic article: in the absorbent disinfection dry powder provided by the invention, hydroscopic high-molecular resin is polymerized by the acrylic acid height, and is nontoxic, harmless, and metallic article without corrosiveness, therefore, is not damaged airframe and parts yet.Another composition sym-closene, belong to organic chlorine-containing disinfectant, aluminium alloy had slight corrosivity, but content is seldom in absorbent disinfection dry powder of the present invention because of it, corrosiveness is weakened, and after the effect of target handled thing, suction is cured as gel, in time process by strict operation sequence again, can avoid it to the infringement of metallic article.
Embodiment 15
With reference to the described method of embodiment 6-14, the absorbent disinfection dry powder of embodiment 2-5 preparation to be tested, it has identical character and the effect of absorbent disinfection dry powder of embodiment 1 preparation.
The above only is preferred embodiment of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (6)
1. an absorbent disinfection dry powder is characterized in that, by percentage to the quality, is comprised of the polyacrylic hydroscopic high-molecular resin of 90-99% and the sym-closene of 1-10%;
Described polyacrylic hydroscopic high-molecular resin is that the degree of polymerization is 1,000,000, degree of neutralization is 60%, adopts glycerine to do the synthetic polyacrylic hydroscopic high-molecular resin of crosslinking agent.
2. absorbent disinfection dry powder as claimed in claim 1 is characterized in that, by percentage to the quality, is comprised of the polyacrylic hydroscopic high-molecular resin of 95-97% and the sym-closene of 3-5%.
3. absorbent disinfection dry powder as claimed in claim 1 is characterized in that, by percentage to the quality, the polyacrylic hydroscopic high-molecular resin by 95% and 5% sym-closene form.
4. the preparation method of an absorbent disinfection dry powder comprises following steps:
Step 1: supply raw materials: by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 90-99%, and sym-closene accounts for 1-10%;
Step 2: described polyacrylic hydroscopic high-molecular resin and described sym-closene are passed through respectively 40 mesh sieves;
Step 3: with described polyacrylic hydroscopic high-molecular resin and described sym-closene mixed grinding, cross 60 mesh sieves.
5. preparation method as claimed in claim 4 is characterized in that, described raw material by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 95-97%, sym-closene accounts for 3-5%.
6. such as claim 4 or 5 described preparation methods, it is characterized in that, described raw material by percentage to the quality, the polyacrylic hydroscopic high-molecular resin accounts for 95%, sym-closene accounts for 5%.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101798146A (en) * | 2010-03-24 | 2010-08-11 | 王显平 | Solid composite sterilizing scale inhibiting agent |
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| CN101798146A (en) * | 2010-03-24 | 2010-08-11 | 王显平 | Solid composite sterilizing scale inhibiting agent |
Non-Patent Citations (2)
| Title |
|---|
| 康红梅等.聚丙烯酸系高吸水树脂合成和吸液性能研究.《精细化工中间体》.2004,第34卷(第2期),第56-58页. |
| 聚丙烯酸系高吸水树脂合成和吸液性能研究;康红梅等;《精细化工中间体》;20040430;第34卷(第2期);第56-第58页 * |
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