CN101925596B - 用于治疗糖尿病的β-氨基酸衍生物 - Google Patents

用于治疗糖尿病的β-氨基酸衍生物 Download PDF

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Publication number
CN101925596B
CN101925596B CN200880125427.7A CN200880125427A CN101925596B CN 101925596 B CN101925596 B CN 101925596B CN 200880125427 A CN200880125427 A CN 200880125427A CN 101925596 B CN101925596 B CN 101925596B
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phenyl
dihydro
oxo
propionamide
pyridin
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Expired - Fee Related
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CN200880125427.7A
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Chinese (zh)
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CN101925596A (zh
Inventor
S·本德尔
L·T·布格多夫
U·埃姆德
N·拜尔
J·格莱茨
C·查隆
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Merck Patent GmbH
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Merck Patent GmbH
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
CN200880125427.7A 2008-01-24 2008-12-23 用于治疗糖尿病的β-氨基酸衍生物 Expired - Fee Related CN101925596B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08001305.5 2008-01-24
EP08001305 2008-01-24
PCT/EP2008/011099 WO2009092432A1 (en) 2008-01-24 2008-12-23 Beta-amino acid derivatives for treatment of diabetes

Publications (2)

Publication Number Publication Date
CN101925596A CN101925596A (zh) 2010-12-22
CN101925596B true CN101925596B (zh) 2014-05-28

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Country Link
US (1) US8431602B2 (enExample)
EP (1) EP2231640B1 (enExample)
JP (1) JP5623914B2 (enExample)
KR (1) KR20100110367A (enExample)
CN (1) CN101925596B (enExample)
AR (1) AR070232A1 (enExample)
AU (1) AU2008348817B2 (enExample)
BR (1) BRPI0821827A2 (enExample)
CA (1) CA2712998A1 (enExample)
CY (1) CY1112919T1 (enExample)
DK (1) DK2231640T3 (enExample)
EA (1) EA017775B1 (enExample)
ES (1) ES2388475T3 (enExample)
HR (1) HRP20120510T1 (enExample)
IL (1) IL206904A0 (enExample)
MX (1) MX2010007926A (enExample)
PL (1) PL2231640T3 (enExample)
PT (1) PT2231640E (enExample)
SI (1) SI2231640T1 (enExample)
WO (1) WO2009092432A1 (enExample)
ZA (1) ZA201006002B (enExample)

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WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
IL291017B2 (en) 2015-10-21 2023-11-01 Otsuka Pharma Co Ltd Benzolactam compounds as protein kinase inhibitors
GB201706327D0 (en) 2017-04-20 2017-06-07 Otsuka Pharma Co Ltd A pharmaceutical compound
WO2024229228A2 (en) * 2023-05-02 2024-11-07 The Rockefeller University 1-oxoisoindolin-2-yl amide activators of vcp and derivatives thereof

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US6482951B2 (en) * 2000-12-13 2002-11-19 Hoffmann-La Roche Inc. Isoindolin-1-one glucokinase activators
BR0315316A (pt) 2002-10-15 2005-08-16 Celgene Corp Métodos de tratar, prevenir ou controlar uma sìndrome mielodisplásica, e de reduzir ou evitar um efeito adverso associado com a administração de um segundo ingrediente ativo em um paciente sofrendo de uma sìndrome mielodisplásica, composição farmacêutica, forma de dosagem unitária, e, kit
CA2511843C (en) * 2002-12-30 2012-04-24 Celgene Corporation Fluoroalkoxy-substituted 1,3-dihydro-isoindolyl compounds and their pharmaceutical uses
AU2005302523A1 (en) * 2004-10-28 2006-05-11 Celgene Corporation Methods and compositions using PDE4 modulators for treatment and management of central nervous system injury
JP5386350B2 (ja) * 2006-05-31 2014-01-15 タケダ カリフォルニア インコーポレイテッド グルコキナーゼ活性剤としての、インダゾールおよびイソインドール誘導体

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JP2011510029A (ja) 2011-03-31
KR20100110367A (ko) 2010-10-12
IL206904A0 (en) 2010-12-30
WO2009092432A1 (en) 2009-07-30
ZA201006002B (en) 2011-04-28
MX2010007926A (es) 2010-08-09
EP2231640B1 (en) 2012-06-06
ES2388475T3 (es) 2012-10-15
HRP20120510T1 (hr) 2012-07-31
PT2231640E (pt) 2012-08-23
EP2231640A1 (en) 2010-09-29
CN101925596A (zh) 2010-12-22
JP5623914B2 (ja) 2014-11-12
BRPI0821827A2 (pt) 2015-06-16
SI2231640T1 (sl) 2012-09-28
CY1112919T1 (el) 2016-04-13
AU2008348817A1 (en) 2009-07-30
US20100331346A1 (en) 2010-12-30
AU2008348817B2 (en) 2011-12-15
EA017775B1 (ru) 2013-03-29
AR070232A1 (es) 2010-03-25
US8431602B2 (en) 2013-04-30
CA2712998A1 (en) 2009-07-30
PL2231640T3 (pl) 2012-09-28
EA201001174A1 (ru) 2011-02-28
DK2231640T3 (da) 2012-07-16

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