CN101849017A - 具有下调的维生素b12系统的微生物 - Google Patents
具有下调的维生素b12系统的微生物 Download PDFInfo
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- CN101849017A CN101849017A CN200880020285A CN200880020285A CN101849017A CN 101849017 A CN101849017 A CN 101849017A CN 200880020285 A CN200880020285 A CN 200880020285A CN 200880020285 A CN200880020285 A CN 200880020285A CN 101849017 A CN101849017 A CN 101849017A
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- 239000002151 riboflavin Substances 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 235000019515 salmon Nutrition 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000003153 stable transfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- VNOYUJKHFWYWIR-ITIYDSSPSA-N succinyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCC(O)=O)O[C@H]1N1C2=NC=NC(N)=C2N=C1 VNOYUJKHFWYWIR-ITIYDSSPSA-N 0.000 description 1
- 238000009923 sugaring Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000005460 tetrahydrofolate Substances 0.000 description 1
- 101150014006 thrA gene Proteins 0.000 description 1
- 229910021654 trace metal Inorganic materials 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 238000013518 transcription Methods 0.000 description 1
- 230000035897 transcription Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 229910000406 trisodium phosphate Inorganic materials 0.000 description 1
- 235000019801 trisodium phosphate Nutrition 0.000 description 1
- 229960003281 tyrothricin Drugs 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
- C12P19/40—Nucleosides having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07110382.4 | 2007-06-15 | ||
| EP07110382 | 2007-06-15 | ||
| EP08157115.0 | 2008-05-28 | ||
| EP08157115 | 2008-05-28 | ||
| PCT/EP2008/057158 WO2008152016A1 (en) | 2007-06-15 | 2008-06-09 | Microorganisms with deregulated vitamin b12 system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101849017A true CN101849017A (zh) | 2010-09-29 |
Family
ID=39769554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200880020285A Pending CN101849017A (zh) | 2007-06-15 | 2008-06-09 | 具有下调的维生素b12系统的微生物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20100047881A1 (enExample) |
| EP (1) | EP2158324A1 (enExample) |
| JP (1) | JP2010530223A (enExample) |
| KR (1) | KR20100049012A (enExample) |
| CN (1) | CN101849017A (enExample) |
| BR (1) | BRPI0812515A2 (enExample) |
| RU (1) | RU2010101001A (enExample) |
| WO (1) | WO2008152016A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113025729A (zh) * | 2020-12-24 | 2021-06-25 | 复旦大学 | 结核分枝杆菌对氨基水杨酸耐药相关的基因突变位点及其应用 |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2712779C (en) | 2008-01-22 | 2021-03-16 | Genomatica, Inc. | Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol |
| CN101981202B (zh) | 2008-01-23 | 2013-09-11 | 巴斯夫欧洲公司 | 发酵生产1,5-二氨基戊烷的方法 |
| JP5755884B2 (ja) | 2008-03-05 | 2015-07-29 | ジェノマティカ， インコーポレイテッド | 第一級アルコールを産生する生物 |
| JP2011519561A (ja) | 2008-05-01 | 2011-07-14 | ジェノマティカ， インコーポレイテッド | メタクリル酸の産生のための微生物 |
| KR20110097951A (ko) | 2008-12-16 | 2011-08-31 | 게노마티카 인코포레이티드 | 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법 |
| BRPI1013426A2 (pt) | 2009-04-30 | 2016-11-08 | Genomatica Inc | organismos para produção de 1,3-butanodiol |
| US8993285B2 (en) | 2009-04-30 | 2015-03-31 | Genomatica, Inc. | Organisms for the production of isopropanol, n-butanol, and isobutanol |
| EP2462221B1 (en) | 2009-08-05 | 2017-02-22 | Genomatica, Inc. | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
| KR20180014240A (ko) | 2009-10-23 | 2018-02-07 | 게노마티카 인코포레이티드 | 아닐린의 제조를 위한 미생물 |
| CN109136161A (zh) | 2009-12-10 | 2019-01-04 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
| CA2787314A1 (en) | 2010-01-29 | 2011-08-04 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of p-toluate and terephthalate |
| US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
| JP2013535203A (ja) | 2010-07-26 | 2013-09-12 | ジェノマティカ・インコーポレイテッド | 芳香族、２，４−ペンタジエノエートおよび１，３−ブタジエンを生合成するための微生物および方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6432686B1 (en) * | 1998-05-12 | 2002-08-13 | E. I. Du Pont De Nemours And Company | Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport |
| JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
| DE10239308A1 (de) * | 2002-08-27 | 2004-03-11 | Basf Ag | Verfahren zur fermentativen Herstellung von schwefelhaltigen Feinchemikalien |
| WO2006138689A2 (en) * | 2005-06-17 | 2006-12-28 | Microbia, Inc. | Improved amino acid and metabolite biosynthesis |
-
2008
- 2008-06-09 EP EP08760723A patent/EP2158324A1/en not_active Withdrawn
- 2008-06-09 WO PCT/EP2008/057158 patent/WO2008152016A1/en not_active Ceased
- 2008-06-09 JP JP2010511606A patent/JP2010530223A/ja not_active Withdrawn
- 2008-06-09 BR BRPI0812515-5A2A patent/BRPI0812515A2/pt not_active IP Right Cessation
- 2008-06-09 RU RU2010101001/10A patent/RU2010101001A/ru not_active Application Discontinuation
- 2008-06-09 US US12/518,531 patent/US20100047881A1/en not_active Abandoned
- 2008-06-09 CN CN200880020285A patent/CN101849017A/zh active Pending
- 2008-06-09 KR KR1020107000839A patent/KR20100049012A/ko not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113025729A (zh) * | 2020-12-24 | 2021-06-25 | 复旦大学 | 结核分枝杆菌对氨基水杨酸耐药相关的基因突变位点及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20100047881A1 (en) | 2010-02-25 |
| WO2008152016A1 (en) | 2008-12-18 |
| WO2008152016A9 (en) | 2009-05-07 |
| KR20100049012A (ko) | 2010-05-11 |
| JP2010530223A (ja) | 2010-09-09 |
| RU2010101001A (ru) | 2011-07-20 |
| EP2158324A1 (en) | 2010-03-03 |
| BRPI0812515A2 (pt) | 2014-12-30 |
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