CN101842088B - 用于包封亲水性和/或亲油性分子的水性-核脂质纳米胶囊 - Google Patents

用于包封亲水性和/或亲油性分子的水性-核脂质纳米胶囊 Download PDF

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Publication number
CN101842088B
CN101842088B CN200880114087.8A CN200880114087A CN101842088B CN 101842088 B CN101842088 B CN 101842088B CN 200880114087 A CN200880114087 A CN 200880114087A CN 101842088 B CN101842088 B CN 101842088B
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oil
water
surfactant
aqueous
phase
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Expired - Fee Related
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CN200880114087.8A
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English (en)
Chinese (zh)
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CN101842088A (zh
Inventor
N·安东
P·索尼耶
J·P·伯努瓦
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Universite dAngers
Institut National de la Sante et de la Recherche Medicale INSERM
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University Angers
Institut National de la Sante et de la Recherche Medicale INSERM
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/87—Polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/16—Interfacial polymerisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CN200880114087.8A 2007-09-18 2008-09-18 用于包封亲水性和/或亲油性分子的水性-核脂质纳米胶囊 Expired - Fee Related CN101842088B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07291109.2 2007-09-18
EP07291109A EP2039352A1 (en) 2007-09-18 2007-09-18 Aqueous-core lipid nanocapsules for encapsulating hydrophilic and/or lipophilic molecules
PCT/EP2008/062435 WO2009037310A2 (en) 2007-09-18 2008-09-18 Aqueous-core lipid nanocapsules for encapsulating hydrophilic and/or lipophilic molecules

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201410049011.9A Division CN103800304A (zh) 2007-09-18 2008-09-18 用于包封亲水性和/或亲油性分子的组合物

Publications (2)

Publication Number Publication Date
CN101842088A CN101842088A (zh) 2010-09-22
CN101842088B true CN101842088B (zh) 2014-03-12

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CN200880114087.8A Expired - Fee Related CN101842088B (zh) 2007-09-18 2008-09-18 用于包封亲水性和/或亲油性分子的水性-核脂质纳米胶囊
CN201410049011.9A Pending CN103800304A (zh) 2007-09-18 2008-09-18 用于包封亲水性和/或亲油性分子的组合物

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CN201410049011.9A Pending CN103800304A (zh) 2007-09-18 2008-09-18 用于包封亲水性和/或亲油性分子的组合物

Country Status (7)

Country Link
US (1) US9522121B2 (https=)
EP (2) EP2039352A1 (https=)
JP (2) JP5989964B2 (https=)
KR (1) KR20100074196A (https=)
CN (2) CN101842088B (https=)
CA (1) CA2699802A1 (https=)
WO (1) WO2009037310A2 (https=)

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US9393315B2 (en) 2011-06-08 2016-07-19 Nitto Denko Corporation Compounds for targeting drug delivery and enhancing siRNA activity
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JP4834775B2 (ja) 2010-03-04 2011-12-14 株式会社 資生堂 日焼け止め用組成物
US10196637B2 (en) 2011-06-08 2019-02-05 Nitto Denko Corporation Retinoid-lipid drug carrier
CN102441355B (zh) * 2011-08-29 2013-10-30 华南理工大学 一种嵌段离聚体水相自组装纳米胶囊及其制备方法
US20130251855A1 (en) * 2012-03-21 2013-09-26 Pepsico, Inc. Aqueous product comprising oil-containing microcapsules and method for the manufacture thereof
EP2808355B1 (en) 2012-06-25 2016-12-21 LG Chem, Ltd. Emulsion composition for preparing polyakylene carbonate molded foam and resin molded foam prepared using same
ES2670995T3 (es) 2013-03-12 2018-06-04 Cephalon, Inc. Formulaciones de nanopartículas y macropartículas
JP6377913B2 (ja) * 2013-04-16 2018-08-22 積水化学工業株式会社 マイクロカプセルの製造方法及びマイクロカプセル
TWI482782B (zh) * 2013-05-31 2015-05-01 Univ Nat Chiao Tung 架接抗體之雙乳化核殼奈米結構
CN103271406B (zh) * 2013-06-08 2014-07-16 吉林大学 一种复合型两亲性芯材微胶囊冲剂及其制备方法
FR3008900B1 (fr) * 2013-07-25 2018-03-30 Centre Nat Rech Scient Nanoparticules lipidiques multicompartimentees
GB2520370B (en) 2014-05-01 2016-09-14 Frito Lay Trading Co Gmbh Snack food seasoning
GB2520371B (en) * 2014-05-01 2016-09-14 Frito Lay Trading Co Gmbh Snack food seasoning
AU2015265874B2 (en) * 2014-05-30 2020-05-14 AbbVie Deutschland GmbH & Co. KG Highly drug-loaded poly(alkyl 2-cyanoacrylate) nanocapsules
JP6572598B2 (ja) * 2015-04-02 2019-09-11 日本製鉄株式会社 ナノ粒子の粒径測定方法
CN111545143A (zh) * 2015-04-09 2020-08-18 沙特阿拉伯石油公司 用于提高烃采收的胶囊型纳米组合物及其制备方法
KR102692648B1 (ko) * 2015-12-04 2024-08-06 (주)아모레퍼시픽 변성 단백질 수상 분산입자를 포함하는 화장료 조성물 및 이의 제조방법
CN106942771A (zh) * 2017-04-06 2017-07-14 贝因美婴童食品股份有限公司 一种用于制备营养品的胶囊
CN112368562A (zh) * 2018-07-11 2021-02-12 香港大学 用于液滴的连续和定量收集的自动微流控系统
FR3092833B1 (fr) * 2019-02-18 2021-07-16 Commissariat Energie Atomique Procede de fabrication de nanoparticules hybrides metal/polymere a faible distribution de tailles par polymerisation en mini-emulsion

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Also Published As

Publication number Publication date
WO2009037310A3 (en) 2010-02-18
US20100297247A1 (en) 2010-11-25
EP2187877A2 (en) 2010-05-26
JP2014221802A (ja) 2014-11-27
WO2009037310A2 (en) 2009-03-26
CN103800304A (zh) 2014-05-21
EP2039352A1 (en) 2009-03-25
JP2010539221A (ja) 2010-12-16
CA2699802A1 (en) 2009-03-26
JP5989964B2 (ja) 2016-09-07
KR20100074196A (ko) 2010-07-01
CN101842088A (zh) 2010-09-22
US9522121B2 (en) 2016-12-20

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