CN101827604B - 焦虑治疗 - Google Patents

焦虑治疗 Download PDF

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Publication number
CN101827604B
CN101827604B CN200880104999.7A CN200880104999A CN101827604B CN 101827604 B CN101827604 B CN 101827604B CN 200880104999 A CN200880104999 A CN 200880104999A CN 101827604 B CN101827604 B CN 101827604B
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CN
China
Prior art keywords
anxiety
patient
arg
xaa
prt
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN200880104999.7A
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English (en)
Chinese (zh)
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CN101827604A (zh
Inventor
A·塔斯克
T·杜塞特
M·蒂米安斯基
K·门多萨
M·P·贝尔马里斯
D·加曼
P·S·卢
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NoNO Inc
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NoNO Inc
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Publication of CN101827604B publication Critical patent/CN101827604B/zh
Expired - Fee Related legal-status Critical Current
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1787—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN200880104999.7A 2007-07-03 2008-07-02 焦虑治疗 Expired - Fee Related CN101827604B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94789207P 2007-07-03 2007-07-03
US60/947,892 2007-07-03
PCT/US2008/069085 WO2009006548A2 (en) 2007-07-03 2008-07-02 Treatment for anxiety

Publications (2)

Publication Number Publication Date
CN101827604A CN101827604A (zh) 2010-09-08
CN101827604B true CN101827604B (zh) 2014-05-07

Family

ID=40226818

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880104999.7A Expired - Fee Related CN101827604B (zh) 2007-07-03 2008-07-02 焦虑治疗

Country Status (10)

Country Link
US (2) US8008253B2 (OSRAM)
EP (1) EP2175873B1 (OSRAM)
JP (2) JP5775303B2 (OSRAM)
KR (1) KR101604428B1 (OSRAM)
CN (1) CN101827604B (OSRAM)
AU (1) AU2008272903B2 (OSRAM)
CA (1) CA2692412C (OSRAM)
DK (1) DK2175873T3 (OSRAM)
ES (1) ES2555172T3 (OSRAM)
WO (1) WO2009006548A2 (OSRAM)

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US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
AU2009246316B2 (en) * 2008-05-16 2014-06-19 Nono Inc. Treatment for epilepsy
JP5801197B2 (ja) 2008-09-03 2015-10-28 ノノ インコーポレイテッド 痛みの治療に関する薬剤及び方法
AU2013251426A1 (en) * 2012-04-27 2014-11-20 Indiana University Research And Technology Corporation Compositions and methods for treating PTSD and related diseases
WO2015068558A1 (ja) 2013-11-05 2015-05-14 三菱樹脂株式会社 粘着剤組成物
JP6388023B2 (ja) 2014-03-10 2018-09-12 三菱ケミカル株式会社 画像表示装置構成用積層体の製造方法
US10206973B2 (en) * 2014-05-28 2019-02-19 Nono Inc. Chloride salt of TAT-NR2B9c
ES2843724T3 (es) 2015-11-30 2021-07-20 Inst Nat Sante Rech Med Antagonistas de NMDAR para el tratamiento de la angiogénesis tumoral
TWI799903B (zh) 2016-02-08 2023-04-21 日商三菱化學股份有限公司 透明雙面黏著片及黏著片積層體
TWI799372B (zh) 2016-02-08 2023-04-21 日商三菱化學股份有限公司 透明雙面黏著片及黏著片積層體
EP3450448B1 (en) * 2016-04-27 2021-04-07 Biocells (Beijing) Biotech Co., Ltd. Therapeutic peptide for excitatory neurotoxicity-related injuries
CN107312069B (zh) * 2016-04-27 2018-11-06 拜西欧斯（北京）生物技术有限公司 兴奋性神经毒性相关损伤的治疗肽
CN106632601B (zh) * 2016-11-16 2020-10-20 中国科学院昆明动物研究所 一种阻断突触长时程增强（ltp）的短肽及其应用
AU2017422458B2 (en) * 2017-07-05 2021-07-15 Biocells (Beijing) Biotech Co., Ltd. Polypeptide pharmaceutically acceptable salt et use thereof
JP7073486B2 (ja) * 2017-09-30 2022-05-23 ▲拝▼西欧斯（北京）生物技▲術▼有限公司 興奮性神経毒性に関連した損傷の治療用ペプチド組成物
FR3075038B1 (fr) 2017-12-15 2020-03-06 Melchior Material And Life Science France Utilisation de la fluoroethylnormemantine pour la prevention de l'apparition et le traitement de l'anxiete
US20220370546A1 (en) * 2019-11-05 2022-11-24 Kyoto University Peptide, composition, and method for treating, preventing, or ameliorating mood disorder
CN111285923B (zh) * 2020-03-05 2023-02-03 成都奥达生物科技有限公司 一种psd-95抑制剂
CN113735938B (zh) 2021-07-30 2024-11-08 英纳氏(珠海)药业有限公司 一种神经保护多肽化合物及其应用

Citations (2)

* Cited by examiner, † Cited by third party
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US6723838B1 (en) * 1998-04-22 2004-04-20 Johns Hopkins University Signal transducing synaptic molecules and uses thereof
CN1747735A (zh) * 2003-02-17 2006-03-15 诺瓦提斯公司 S－10－羟基－10,11－二氢－卡马西平在治疗焦虑和双相情感障碍中的用途

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6942981B1 (en) * 1999-05-14 2005-09-13 Arbor Vita Corporation Method of determining interactions with PDZ-domain polypeptides
US20060148711A1 (en) * 1999-05-14 2006-07-06 Arbor Vita Corporation Molecular interactions in neurons
US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6432985B2 (en) 2000-04-25 2002-08-13 Hoffmann-La Roche Inc. Neuroprotective substituted piperidine compounds with activity as NMDA NR2B subtype selective antagonists
JP2004501901A (ja) * 2000-06-26 2004-01-22 メルク　エンド　カムパニー　インコーポレーテッド イミノピリミジン系ｎｍｄａｎｒ２ｂ受容体拮抗薬
FI20012082A0 (fi) * 2001-10-26 2001-10-26 Paeivi Liesi Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi
US6713490B2 (en) 2002-04-26 2004-03-30 Pfizer, Inc. 3,4-dihydroquinolin-2(1H)-one compounds as NR2B receptor antagonists
EP1578365A4 (en) * 2002-11-14 2009-09-23 Arbor Vita Corp MOLECULAR INTERACTIONS IN NEURONS
WO2005017203A2 (en) * 2003-07-11 2005-02-24 Yale University Systems and methods for diagnosing and treating psychological and behavioral conditions
JP2007512251A (ja) * 2003-11-12 2007-05-17 メルク　エンド　カムパニー　インコーポレーテッド ４−フェニルピペリジンスルホニルグリシン輸送体インヒビター
HU226977B1 (en) * 2004-07-29 2010-04-28 Richter Gedeon Nyrt Kynurenic acid amide derivatives, pharmaceutical compositions containing them and process for producing them
US20060167075A1 (en) * 2005-01-25 2006-07-27 Pearson James P Modulators of FAAH
TW200640529A (en) * 2005-02-28 2006-12-01 Thomas Christian Lines Composition for treating mental health disorders
US7588911B2 (en) * 2005-06-23 2009-09-15 Arbor Vita Corporation Assays for detecting inhibitors of binding between COX-2 and PDZ proteins
WO2007079406A1 (en) 2005-12-30 2007-07-12 Arbor Vita Corporation Small molecule inhibitors of pdz interactions
US8262847B2 (en) * 2006-12-29 2012-09-11 Lam Research Corporation Plasma-enhanced substrate processing method and apparatus
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
US8080518B2 (en) * 2007-12-05 2011-12-20 Arbor Vita Corporation Co-administration of an agent linked to an internalization peptide with an anti-inflammatory

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723838B1 (en) * 1998-04-22 2004-04-20 Johns Hopkins University Signal transducing synaptic molecules and uses thereof
CN1747735A (zh) * 2003-02-17 2006-03-15 诺瓦提斯公司 S－10－羟基－10,11－二氢－卡马西平在治疗焦虑和双相情感障碍中的用途

Also Published As

Publication number Publication date
JP2010532761A (ja) 2010-10-14
CA2692412C (en) 2017-02-07
JP2014129353A (ja) 2014-07-10
US8008253B2 (en) 2011-08-30
ES2555172T3 (es) 2015-12-29
WO2009006548A2 (en) 2009-01-08
CA2692412A1 (en) 2009-01-08
KR20100038366A (ko) 2010-04-14
US20120083449A1 (en) 2012-04-05
US20090036376A1 (en) 2009-02-05
EP2175873A2 (en) 2010-04-21
EP2175873A4 (en) 2011-10-05
AU2008272903A8 (en) 2010-05-06
WO2009006548A3 (en) 2009-03-19
DK2175873T3 (en) 2015-12-14
CN101827604A (zh) 2010-09-08
AU2008272903B2 (en) 2013-08-29
US8536129B2 (en) 2013-09-17
AU2008272903A1 (en) 2009-01-08
JP5775303B2 (ja) 2015-09-09
KR101604428B1 (ko) 2016-03-17
EP2175873B1 (en) 2015-11-11

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Free format text: FORMER OWNER: ARBOR VITA CORP;NONO INC.

Effective date: 20130326

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20130326

Address after: Ontario

Applicant after: NoNO Inc.

Address before: Ontario

Applicant before: NoNo Inc.

Applicant before: Arbor Vita Corp.

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140507

CF01 Termination of patent right due to non-payment of annual fee