ES2555172T3 - Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad - Google Patents

Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad Download PDF

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Publication number
ES2555172T3
ES2555172T3 ES08772390.4T ES08772390T ES2555172T3 ES 2555172 T3 ES2555172 T3 ES 2555172T3 ES 08772390 T ES08772390 T ES 08772390T ES 2555172 T3 ES2555172 T3 ES 2555172T3
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ES
Spain
Prior art keywords
agent
patient
seq
anxiety
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES08772390.4T
Other languages
English (en)
Spanish (es)
Inventor
Andrew Tasker
Tracy Doucette
Michael Tymianski
Kenneth Mendoza
Michael P. Belmares
David Garman
Peter S. Lu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NoNO Inc
Original Assignee
NoNO Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NoNO Inc filed Critical NoNO Inc
Application granted granted Critical
Publication of ES2555172T3 publication Critical patent/ES2555172T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1787Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES08772390.4T 2007-07-03 2008-07-02 Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad Active ES2555172T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94789207P 2007-07-03 2007-07-03
US947892P 2007-07-03
PCT/US2008/069085 WO2009006548A2 (en) 2007-07-03 2008-07-02 Treatment for anxiety

Publications (1)

Publication Number Publication Date
ES2555172T3 true ES2555172T3 (es) 2015-12-29

Family

ID=40226818

Family Applications (1)

Application Number Title Priority Date Filing Date
ES08772390.4T Active ES2555172T3 (es) 2007-07-03 2008-07-02 Péptidos inhibidores de receptores NMDA para uso en en tratamiento de trastornos de la ansiedad

Country Status (10)

Country Link
US (2) US8008253B2 (OSRAM)
EP (1) EP2175873B1 (OSRAM)
JP (2) JP5775303B2 (OSRAM)
KR (1) KR101604428B1 (OSRAM)
CN (1) CN101827604B (OSRAM)
AU (1) AU2008272903B2 (OSRAM)
CA (1) CA2692412C (OSRAM)
DK (1) DK2175873T3 (OSRAM)
ES (1) ES2555172T3 (OSRAM)
WO (1) WO2009006548A2 (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
EP2307035B1 (en) * 2008-05-16 2013-12-04 NoNO Inc. Use of an inhibitor of psd-95treatment for epilepsy
AU2009288088B2 (en) * 2008-09-03 2014-12-04 Nono Inc. Agents and methods for treatment of pain
CA2871782A1 (en) * 2012-04-27 2013-10-31 Indiana University Research And Technology Corporation Compositions and methods for treating ptsd and related diseases
EP3067400A4 (en) 2013-11-05 2017-06-07 Mitsubishi Plastics, Inc. Adhesive composition
KR101888984B1 (ko) 2014-03-10 2018-08-16 미쯔비시 케미컬 주식회사 화상 표시 장치 구성용 적층체의 제조 방법
EP3757134B1 (en) * 2014-05-28 2024-03-06 NoNO Inc. Chloride salt of tat-nr2b9c
ES2843724T3 (es) 2015-11-30 2021-07-20 Inst Nat Sante Rech Med Antagonistas de NMDAR para el tratamiento de la angiogénesis tumoral
KR102652894B1 (ko) 2016-02-08 2024-04-01 미쯔비시 케미컬 주식회사 투명 양면 점착 시트 및 점착 시트 적층체
WO2017138544A1 (ja) 2016-02-08 2017-08-17 三菱ケミカル株式会社 透明両面粘着シート及び粘着シート積層体
CN107312069B (zh) * 2016-04-27 2018-11-06 拜西欧斯(北京)生物技术有限公司 兴奋性神经毒性相关损伤的治疗肽
KR102253900B1 (ko) 2016-04-27 2021-05-18 바이오셀즈(베이징) 바이오테크 코., 엘티디. 흥분성 신경독성 관련 손상 치료용 펩타이드
CN106632601B (zh) * 2016-11-16 2020-10-20 中国科学院昆明动物研究所 一种阻断突触长时程增强(ltp)的短肽及其应用
EP3650460A4 (en) * 2017-07-05 2021-03-17 Biocells (Beijing) Biotech Co., Ltd. PHARMACEUTICAL SALT OF A POLYPEPTID AND ITS USES
EA202090802A1 (ru) * 2017-09-30 2020-08-05 Биоселз (Бейдзин) Биотек Ко., Лтд. Пептидная композиция для лечения повреждений, связанных с возбуждающей нейротоксичностью
FR3075038B1 (fr) 2017-12-15 2020-03-06 Melchior Material And Life Science France Utilisation de la fluoroethylnormemantine pour la prevention de l'apparition et le traitement de l'anxiete
WO2021090894A1 (ja) * 2019-11-05 2021-05-14 国立大学法人京都大学 ペプチド、組成物、及び、気分障害を治療、予防、又は改善する方法
CN111285923B (zh) * 2020-03-05 2023-02-03 成都奥达生物科技有限公司 一种psd-95抑制剂
CN113735938B (zh) 2021-07-30 2024-11-08 英纳氏(珠海)药业有限公司 一种神经保护多肽化合物及其应用

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US6723838B1 (en) 1998-04-22 2004-04-20 Johns Hopkins University Signal transducing synaptic molecules and uses thereof
US6942981B1 (en) 1999-05-14 2005-09-13 Arbor Vita Corporation Method of determining interactions with PDZ-domain polypeptides
US20060148711A1 (en) * 1999-05-14 2006-07-06 Arbor Vita Corporation Molecular interactions in neurons
US7595297B2 (en) * 1999-06-02 2009-09-29 Michael Tymianski Method of reducing injury to mammalian cells
US6369076B1 (en) 1999-10-29 2002-04-09 Merck & Co. Inc. 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists
US6432985B2 (en) 2000-04-25 2002-08-13 Hoffmann-La Roche Inc. Neuroprotective substituted piperidine compounds with activity as NMDA NR2B subtype selective antagonists
CA2412640A1 (en) * 2000-06-26 2002-01-03 Merck & Co., Inc. Iminopyrimidine nmda nr2b receptor antagonists
WO2004045535A2 (en) 2002-11-14 2004-06-03 Arbor Vita Corporation Molecular interactions in neurons
FI20012082A0 (fi) 2001-10-26 2001-10-26 Paeivi Liesi Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi
US6713490B2 (en) * 2002-04-26 2004-03-30 Pfizer, Inc. 3,4-dihydroquinolin-2(1H)-one compounds as NR2B receptor antagonists
GB0303613D0 (en) * 2003-02-17 2003-03-19 Novartis Ag Use of organic compounds
US20050084880A1 (en) 2003-07-11 2005-04-21 Ronald Duman Systems and methods for diagnosing & treating psychological and behavioral conditions
EP1684759A4 (en) 2003-11-12 2009-06-10 Merck & Co Inc 4-phenyl-piperidinosulfonyl-Glycine-TRANSPORTER INHIBITORS
HU226977B1 (en) * 2004-07-29 2010-04-28 Richter Gedeon Nyrt Kynurenic acid amide derivatives, pharmaceutical compositions containing them and process for producing them
US20060167075A1 (en) 2005-01-25 2006-07-27 Pearson James P Modulators of FAAH
TW200640529A (en) 2005-02-28 2006-12-01 Thomas Christian Lines Composition for treating mental health disorders
WO2007002395A1 (en) * 2005-06-23 2007-01-04 Arbor Vita Corporation Methods and compositions for modulating cox
RU2008131330A (ru) * 2005-12-30 2010-02-10 Арбор Вита Корпорейшн (Us) Низкомолекулярные ингибиторы взаимодействия pdz
US8262847B2 (en) * 2006-12-29 2012-09-11 Lam Research Corporation Plasma-enhanced substrate processing method and apparatus
US8008253B2 (en) 2007-07-03 2011-08-30 Andrew Tasker Treatment for anxiety
US8080518B2 (en) * 2007-12-05 2011-12-20 Arbor Vita Corporation Co-administration of an agent linked to an internalization peptide with an anti-inflammatory

Also Published As

Publication number Publication date
US20090036376A1 (en) 2009-02-05
AU2008272903A1 (en) 2009-01-08
EP2175873B1 (en) 2015-11-11
CN101827604B (zh) 2014-05-07
KR101604428B1 (ko) 2016-03-17
JP5775303B2 (ja) 2015-09-09
KR20100038366A (ko) 2010-04-14
US20120083449A1 (en) 2012-04-05
JP2010532761A (ja) 2010-10-14
US8008253B2 (en) 2011-08-30
EP2175873A4 (en) 2011-10-05
CA2692412A1 (en) 2009-01-08
JP2014129353A (ja) 2014-07-10
AU2008272903A8 (en) 2010-05-06
CN101827604A (zh) 2010-09-08
EP2175873A2 (en) 2010-04-21
CA2692412C (en) 2017-02-07
WO2009006548A2 (en) 2009-01-08
US8536129B2 (en) 2013-09-17
AU2008272903B2 (en) 2013-08-29
WO2009006548A3 (en) 2009-03-19
DK2175873T3 (en) 2015-12-14

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