CN101822699B - Traditional Chinese medicine for treating psoriasis and preparation method thereof - Google Patents
Traditional Chinese medicine for treating psoriasis and preparation method thereof Download PDFInfo
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- CN101822699B CN101822699B CN2010102052182A CN201010205218A CN101822699B CN 101822699 B CN101822699 B CN 101822699B CN 2010102052182 A CN2010102052182 A CN 2010102052182A CN 201010205218 A CN201010205218 A CN 201010205218A CN 101822699 B CN101822699 B CN 101822699B
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Abstract
The invention relates to a traditional Chinese medicine for treating psoriasis and a preparation method thereof, which relate to a traditional Chinese medicine for treating dermatosis and a preparation method thereof. The invention solves the problems of larger side effect of psoriasis treatment through Western medicine, and long treatment time, unobvious effect and easy relapse of psoriasis treatment through Chinese medicine at present. The traditional Chinese medicine for treating psoriasis is prepared from red lead, calomel, aluminum powder, rosin, gypsum, brine and 9-degree rice vinegar. The preparation method comprises the following steps: 1. weighing red lead, calomel, aluminum powder, rosin, gypsum, brine and 9-degree rice vinegar; 2. pulverizing red lead, rosin and gypsum into power; and 3. mixing pulverized red lead, pulverized rosin and pulverized gypsum powder with calomel, aluminum powder, brine and 9-degree rice vinegar, uniformly stirring and placing for 10 days to obtain the traditional Chinese medicine for treating psoriasis. Before use, the traditional Chinese medicine for treating psoriasis needs to be uniformly shaken, is then coated at a focus, is applied twice per day with 10 days as a treatment period and can cure through 1 to 3 treatment periods, and the cure rate reaches 100 percent.
Description
Technical field
The present invention relates to dermopathic Chinese medicine of a kind of treatment and preparation method thereof.
Background technology
So-called " tinea " medically is meant because some dermatosiss that fungal infection causes, for example tinea capitis, tinea cruris, tinea corporis, tinea manus and pedis, fingernail tinea etc.The partial scurf of these tinea is placed on microscopically often can finds fungal mycelia or fungal spore, use antifungal drug to treat and often can obtain better curative effect.Psoriasis is not then caused by fungal infection, medically is referred to as psoriasis.Its pathogenic factor is very complicated, and it is often invalid to treat with antifungal drug.
Psoriasis is characterized in that occurring repeatedly the silvery white dry squama of multilamellar as a kind of common chronic dermatosis on erythema.Traditional Chinese medical science Gu is referred to as “ Bai Mange ", ancient doctor's nationality also is referred to as psoriasis.Doctor trained in Western medicine is called psoriasis (Psoriasis), is commonly called as psoriasis.Psoriasis can betide any position, is common in the position such as the patella ulnaris dorsal part that often suffer external pressure friction especially, extremity are stretched near side, the rumpbone position and scalp etc. is located, and both sides are symmetry more or less often.The gelatinous layer cell of psoriatic's epidermis can not full maturity, becomes Parakeratotic cell, and the gap of filling air is arranged between the micelle.The finding squama is silvery white Muscovitum shape clinically, is exactly because the cause of aeriferous parakeratosis horny layer refracted ray.In the parakeratosis horny layer or below it.Often can see the disrupted neutrophil cell group of cell.These leukocyte in groups mix together with the epidermis cell of some degeneration, become microabscess, are called sieve microabscess, are one of psoriasis pathology features.Below Parakeratotic cell, the granular layer cell seldom, or complete obiteration.Prickle cell layer generation intercellular edema but do not have vesicle and form.The incomplete leukocyte of some scattered body often in intercellular substance, trochanterellus prolongs because of edema, and length is all similar.In intradermal, around the blood vessel of shallow-layer cellular infiltration is arranged, be mainly lymphocyte.The quiet disease of pustular silver is identical with the tissue variation of acrodermatitis continua and impetigo herpetiformis, and dagger-axe Jie of spongy section (Kogoj) microabscess is all arranged.Because the epidermis cell of edema breaks, cell wall is linked to be spongy, and the neutrophilic granulocyte migration of corium becomes spongy abscess to spongy bleb intracavity, and section's dagger-axe Jie microabscess just comes across the top of epidermis easily.When abscess is advanced to horny layer with epidermis cell, and become bigger monro's abscesses.Other change as parakeratosis, trochanterellus net ridge prolong, the corium superficial part has cellular infiltration etc. change with ordinary psoriasic tissue change similar substantially, in the neutrophil cell intrusion epidermis that has.
According to investigations, psoriatic sickness rate accounts for 0.1% ~ 3% of world population, has reached 4,580,000 people by China psoriatic in 2007.The obstinate refractory of psoriasis still is listed in the important subject in department of dermatologry field, the world today, is one of whole world department of dermatologry keypoint control disease.Because the western medical treatment psoriasis mainly is to eliminate symptom, avoid further deterioration, can't effect a radical cure, and side effect is bigger, so in the national psoriasis control cooperation meeting of holding in recent years, the participant expert is consistent to be thought " doctor trained in Western medicine anticarcinogen and hormone medicine have serious adverse, should avoid using as far as possible ".
The traditional Chinese medical science is thought feelings will internal injury, obstruction of QI, and strongly fragrant fire-transformation of a specified duration, psoriasis takes place in scorchingly hot lying prostrate in nutrient blood.Therefore, at present mostly be that for the psoriasis treatment traditional Chinese medical science this treatment can be played certain effect at the hot-tempered treatment of heat in blood, blood stasis and elimination, but the medicine of used heat-clearing and toxic substances removing or internal organs conditioning, there is long, DeGrain of treatment time, easily the defective of recurrence.
Summary of the invention
It is bigger to the objective of the invention is to solve the side effect of western medical treatment psoriasis, and long, DeGrain of present Chinese traditional treatment curing psoriasis time, the defective of easy recurrence, and psoriasic Chinese medicine of a kind of treatment that provides and preparation method thereof.
The present invention treats psoriasic Chinese medicine, and (different name: Plumbum preparatium, plumbous red, molecular formula is Pb by 13 ~ 17g Plumbum preparatium
3O
4), 13 ~ 17g Calomelas (different name: hydrargyrum powder supplement to the Herbal, high and steep powder " Japan hanako materia medica ", CALOMELAS " the good book on Chinese herbal medicine of helping ", greasy powder " rare treasure side passes from generation to generation in a family ", argentum powder " book on Chinese herbal medicine is stated " is swept basin " book on Chinese herbal medicine is just read "), 13 ~ 17g aluminium powder, 13 ~ 17g Colophonium, 13 ~ 17g Gypsum Fibrosum (different name: microlith, thin Gypsum Fibrosum " not Lu ", soft gypsum " Amplification on Materia Medica addendum ", Mirabilitum crystallina " detailed outline ", white tiger), 240 ~ 260g salt and 480 ~ 520g9 degree rice vinegar make.
The psoriasic Chinese medicine of above-mentioned treatment is realized by following step: one, take by weighing Plumbum preparatium 13 ~ 17g, Calomelas 13 ~ 17g, aluminium powder 13 ~ 17g, Colophonium 13 ~ 17g, Gypsum Fibrosum 13 ~ 17g, salt 240 ~ 260g and 9 degree rice vinegars, 480 ~ 520g; Two, Plumbum preparatium, Colophonium and Gypsum Fibrosum powder are broken into particle diameter less than 100 purpose powder; Three, will place 10 days through Plumbum preparatium, Colophonium and Gypsum Fibrosum powder and Calomelas, aluminium powder salt and the 9 degree rice vinegar mixing and stirring pulverized, psoriasic Chinese medicine promptly obtains medical treatment.
The present invention treats psoriasic Chinese medicine to be needed to shake up before use, and be coated on affected part (covering fully) then and get final product, dispenser on the one 2 times, 10 days is a course of treatment, and cure 1 ~ 3 course of treatment, and cure rate reaches 100%.
Plumbum preparatium---For the crystalline powder of reddish orange, poisonous; Proportion is 9.1, and is water insoluble, and it is strong to have corrosion resistance, high temperature resistant, but not acidproof.
Calomelas---External has bactericidal action, and toxicity is little, but color deepens gradually when exposure, decomposes to generate mercuric chloride and mercury metal, and the two all has severe toxicity.Function cures mainly: parasite killing, counteracting toxic substances, diuretic, relieving constipation.Control scabies, scrofula, syphilis, primary sore, skin ulcer, edema, tympanites, defecation is closed.
Aluminium powder---Light weight, the floating force height, strong covering power is all good to the reflecting properties of light and heat.
Colophonium---be the transparent solid of little Huang to yellowish red color, 70～90 ℃ of softening points, proportion are 1.070～1.085.Nature and flavor: bitter sweet, temperature.Function cures mainly: dispeiling pathogenic wind and removing dampness, the granulation promoting pain relieving is applicable to carbuncle furuncle infections, eczema, traumatic hemorrhage, burn and scald.
Gypsum Fibrosum---monoclinic system mineral, main chemical compositions are calcium sulfate (CaSO
42H
2O).Function cures mainly: give birth to and to use that expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst, heat-clearing and toxic substances removing.The external treatment ulcer sores is burst and is not closed up the burning hot wound of soup.
Salt---nature and flavor: bitter salty, cold.Function cures mainly: control Keshan disease, Kaschin-Beck disease, goiter, hypertension, rheumatic heart disease, chronic bronchitis, dermatitis, wind heat acute conjunctivitis.
The specific embodiment
Technical solution of the present invention is not limited to the following cited specific embodiment, also comprises the combination in any between each specific embodiment.
The specific embodiment one: present embodiment is treated psoriasic Chinese medicine and is made by 13 ~ 17g Plumbum preparatium, 13 ~ 17g Calomelas, 13 ~ 17g aluminium powder, 13 ~ 17g Colophonium, 13 ~ 17g Gypsum Fibrosum, 240 ~ 260g salt and 480 ~ 520g9 degree rice vinegar.
The psoriasis criterion of therapeutical effect:
Cure: the erythra area disappears more than 95% or disappears fully, the General Symptoms complete obiteration.
Take a turn for the better: the erythra area disappears more than 30% ~ 50%, and General Symptoms obviously improves.
Do not heal: the erythra area disappears below 30%.
Present embodiment is treated psoriasic Chinese medicine psoriasic cure rate is reached particularly intractable psoriasis of 100%(), adhere to taking vitamin C after the healing and all do not have recurrence in 18 months.
Plumbum preparatium proportion great majority are positioned at medication coat of the present invention bottom, because of its strong adhesion, can effectively avoid coming off of medication coat, strengthen drug treating time." lead " that is contained in the Plumbum preparatium can strengthen the permeability of effective ingredient.
Because Colophonium and aluminium powder proportion all less than Calomelas, so the Calomelas majority is positioned in the middle of the medication coat, can reduce exposure, effectively control its toxicity in the technical solution of the present invention.
Contain about 3.5 liang of salt alkali in the salt per jin.
9 degree rice vinegars can generate little acetic acid lead and PbO with reaction
2, and can promote the infiltration of active constituents of medicine.
Present embodiment is treated psoriasic Chinese medicine all has very excellent therapeutic effect to scabies, infantile carbuncle eczema, impetigo.
2 ~ 4 days psoriasis wound surface of treatment beginning enlarge to some extent and belong to normal drug reaction, continue treatment psoriasis wound surface and dwindle gradually, until healing.Present embodiment is treated psoriasic Chinese medicine other untoward reaction or intoxicating phenomenon, safe in utilization.
The specific embodiment two: the difference of the present embodiment and the specific embodiment one is: treat psoriasic Chinese medicine and made by 15g Plumbum preparatium, 15g Calomelas, 15g aluminium powder, 15g Colophonium, 15g Gypsum Fibrosum, 250g salt and 500g9 degree rice vinegar.。Other embodiment one is identical.
The specific embodiment three: present embodiment is treated psoriasic Chinese medicine and is realized by following step: one, take by weighing Plumbum preparatium 13 ~ 17g, Calomelas 13 ~ 17g, aluminium powder 13 ~ 17g, Colophonium 13 ~ 17g, Gypsum Fibrosum 13 ~ 17g, salt 240 ~ 260g and 9 degree rice vinegars, 480 ~ 520g; Two, Plumbum preparatium, Colophonium and Gypsum Fibrosum powder are broken into particle diameter less than 100 purpose powder; Three, will place 10 days through Plumbum preparatium, Colophonium and Gypsum Fibrosum powder and Calomelas, aluminium powder salt and the 9 degree rice vinegar mixing and stirring pulverized, psoriasic Chinese medicine promptly obtains medical treatment.
The specific embodiment four: the difference of the present embodiment and the specific embodiment three is: take by weighing Plumbum preparatium 15g, Calomelas 15g, aluminium powder 15g, Colophonium 15g, Gypsum Fibrosum 15g, salt 250g and 9 degree rice vinegar 500g in the step 1.Other step and parameter are identical with embodiment three.
It is 6 kinds that psoriasis is divided into:
1, psoriasis vulgaris: erythra generally occurs in scalp, trunk, extremity are stretched side, are to occur red pimple on skin, and flaring is fused into patch or speckle greatly, there are thicker silvery white phosphorus bits on the surface, out-of-shape, and what have has map or an island sample outward appearance, the skin lesion that has is less, more, be the Caulis et folium pavettae hongkongensis outward appearance, squama layer one deck comes off, wipe scurf gently off and can see the red film of very thin one deck, strike off red film and can see slight petechia, have person to reveal, medically make the sieve shape hemorrhage again for blood.
2, erythrodermic psoriasis: be more serious, more rare is a kind of, this kind of is meant and is the diffusivity redness more than 70% at about whole skin, kermesinus wellability skin lesion, surface have a large amount of bran skin sample scurfs, sometimes in the oxter, thigh root and umbilical part make exfoliation because of swelling and ooze out, oropharynx nose and eye conjunctiva can be congested rubescent, and the patient often has heating fear of cold, symptoms such as headache and general malaise.
3, pustular psoriasis: divide general property and limitation.General property pustule type psoriasis mostly is acute onset, can be in a few days to several weeks general whole body of pustule, the intensive potential pimple of needle point size is arranged earlier, be fused into the pus lake very soon, often with hyperpyrexia, arthralgia and general malaise, routine blood test is chemically examined visible leukocytosis, after abscess is dry, desquamation after scurf comes off, has new abscess to occur again immediately.Limitation pustule type psoriasis is seen with palm toe pustule type psoriasis more, at the both hands palms and toes portion the symmetry erythema is arranged, occur syringe needle on the erythema and arrive Li Daxiao greatly to pimple: dry up voluntarily after about 1 ~ 2 week, new pustule appearance is arranged again behind the desquamation, be continuous course of disease stubbornness repeatedly.
4, psoriasis arthropathica: rarely found, any age all can take place, and can betide big or small joint simultaneously, but common be the little joint of wrist, finger and toes, joint of vertebral column also can take place.The joint of pathological changes has redness, pain, serious articular cavity that hydrops is arranged, juxtra-articular skin turgor limitation of activity, joint stiffness of a specified duration, the ruined situation in visible joint under X line when serious, erythrocyte sedimentation rate is fast, General Symptomies such as the heat that often occurs together, but rheumatoid agglutinating factor is negative, how psoriasis arthropathica, skin lesion also can only have the skin lesion of homeliness type psoriasic erythema and silver bits with the ostraceous skin lesion of thick picture.
5, slap the impetigo of wasting time: comprise and slap waste time pustular psoriasis and pustular bacterid.
6, acrodermatitis continua: the pustule with aseptic is its feature, and good sending out in middle age is most by causing after the wound.
The psoriasic treatment by Chinese herbs psoriasis of treatment that adopts present embodiment to prepare needs before the use to shake up, and is coated on the affected part then, cover fully (thickness is about 1 ~ 2mm), dispenser on the one 2 times, and 10 days is a course of treatment.
Therapeutic effect is as shown in table 1:
Table 1
| ? | Psoriasis vulgaris | Erythrodermic psoriasis | Pustular psoriasis | Psoriasis arthropathica | Slap the impetigo of wasting time | Acrodermatitis continua |
| The treatment patient | 235 people | 45 people | 123 people | 120 people | 132 people | 112 people |
| Cure | 235 people | 45 people | 123 people | 120 people | 132 people | 112 people |
| Take a turn for the better | - | - | - | - | - | - |
| Do not heal | - | - | - | - | - | - |
| Treatment time | 1 ~ 2 course of treatment | 2 ~ 3 courses of treatment | 1 ~ 3 course of treatment | 2 ~ 3 courses of treatment | 2 ~ 3 courses of treatment | 1 ~ 3 course of treatment |
| Cure rate | 100% | 100% | 100% | 100% | 100% | 100% |
Annotate: the psoriasis criterion of therapeutical effect:
Cure: the erythra area disappears more than 95% or disappears fully, the General Symptoms complete obiteration.
Take a turn for the better: the erythra area disappears more than 30% ~ 50%, and General Symptoms obviously improves.
Do not heal: the erythra area disappears below 30%.
Treatment time can be adjusted according to state of an illness situation, and the serious state of an illness can be cured 3 courses of treatment.
Respectively account for 1/3 through what present embodiment was equipped with that the state of an illness among 767 psoriatics of the psoriasic treatment by Chinese herbs of treatment that is in the phase of carrying out, resting stage and catagen.The psoriasic Chinese medicine of treatment that therapeutic outcome explanation present embodiment is prepared all has notable therapeutic effect to the psoriasis of all kinds of different times, and cure rate all reaches 100%.And the psoriasic Chinese medicine of treatment prepared of present embodiment to the cure rate of scabies, infantile carbuncle eczema, impetigo also up to more than 95%.
Follow-up investigation finds, adheres to taking vitamin C after 767 psoriatics that accept the treatment by Chinese herbs that present embodiment prepares cure, and cures in back 18 months rebound phenomenon all not occur.Strengthen the exercise of physical culture present embodiment, the emotion that keeps pleasant, form good dietary habit and often take a solar bath and further obviously to reduce recurrence probability and frequency.
Because medication coat is thin, formulation rate is few, toxic component content is low, there is not the risk of drug intoxication so treat the patient, it is reliable to continue tracing observation proof present embodiment safety of medicine.
Claims (4)
1. the psoriasic Chinese medicine of treatment is characterized in that treating psoriasic Chinese medicine and is made by 13～17g Plumbum preparatium, 13～17g Calomelas, 13～17g aluminium powder, 13～17g Colophonium, 13～17g Gypsum Fibrosum, 240～260g salt and 480～520g9 degree rice vinegar.
2. the psoriasic Chinese medicine of a kind of treatment according to claim 1 is characterized in that treating psoriasic Chinese medicine and is made by 15g Plumbum preparatium, 15g Calomelas, 15g aluminium powder, 15g Colophonium, 15g Gypsum Fibrosum, 250g salt and 500g9 degree rice vinegar.
3. treat psoriasic preparation method of Chinese medicine according to claim 1, it is characterized in that treating psoriasic Chinese medicine and realize: one, take by weighing Plumbum preparatium 13～17g, Calomelas 13～17g, aluminium powder 13～17g, Colophonium 13～17g, Gypsum Fibrosum 13～17g, salt 240～260g and 9 degree rice vinegars, 480～520g by following step; Two, Plumbum preparatium, Colophonium and Gypsum Fibrosum powder are broken into particle diameter less than 100 purpose powder; Three, will place 10 days through Plumbum preparatium, Colophonium and Gypsum Fibrosum powder and Calomelas, aluminium powder, salt and the 9 degree rice vinegar mixing and stirring pulverized, psoriasic Chinese medicine promptly obtains medical treatment.
4. the psoriasic preparation method of Chinese medicine of a kind of treatment according to claim 3 is characterized in that taking by weighing in the step 1 Plumbum preparatium 15g, Calomelas 15g, aluminium powder 15g, Colophonium 15g, Gypsum Fibrosum 15g, salt 250g and 9 degree rice vinegar 500g.
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Effective date of registration: 20170111 Address after: Room 2, unit 11, building 150000, Harbin, south of the city, Heilongjiang Province Patentee after: Zhao Shuyan Address before: Feiketu Xiang A Cheng 150300 cities in Heilongjiang province Harbin City Xinli village two groups Patentee before: Shu Wenyou |
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