CN103920044A - Medicine for treating urethral calculus and preparation method thereof - Google Patents

Medicine for treating urethral calculus and preparation method thereof Download PDF

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CN103920044A
CN103920044A CN201410169466.4A CN201410169466A CN103920044A CN 103920044 A CN103920044 A CN 103920044A CN 201410169466 A CN201410169466 A CN 201410169466A CN 103920044 A CN103920044 A CN 103920044A
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吕宝勇
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Abstract

The invention discloses a medicine for treating urethral calculus and a preparation method thereof, and belongs to the field of traditional Chinese medicine. The medicine is composed of the following effective raw materials: water hyacinth, gomphostemma root, aeginetia indica, common leafflower herb with root, Chinese brake herb, juniperinum, Indian damnacanthus herb, bergia ammannioides roxb, edelweiss, randia cochinchinensis, juniper, eragrostis pilosa, horsetail, hawkweed, Japanese snailseed root and gold sakura. The raw materials of the medicine are compatible, and accord with the theory of traditional Chinese medicine and modern medicine and pharmacology; the medicine has the effects of activating qi and resolving stagnation, treating stranguria and removing calculus, resisting inflammation, promoting urination, dispelling the wind and relieving pain, thus the medicine has unique effects on the symptoms, such as frequent micturition, micturition pain, copious urine, pyuria and hematuresis caused by the urethral calculus. The medicine is convenient to take, is safe, reliable and free of toxic and side effect, and no recrudescence is caused after healing. The medicine has an accurate curative effect for treating urethral calculus, and achieves the aim of treating both symptoms and root causes, thus the medicine is worth being promoted and applied in clinic widely.

Description

A kind of medicine and preparation method for the treatment of calculus of urethra
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of medicine and preparation method for the treatment of calculus of urethra.
Background technology
Calculus of urethra great majority are from bladder and kidney, and calculus can stay in prostatic urethra, bulb and scaphoid fossa place, and minority is sent out in urethral stricture nearside or urethral diverticulum place, and minority is secondary to urethral stricture, atresia of urethra, foreign body or urethral diverticulum.Main manifestations is dysuria, trouble urinating, can be sound of rain pattering shape, sometimes occur that urine stream interrupts and urine retention, urinate and sometimes have obvious pain, and be radiated to penis head, rear calculus of urethra has perineum and scrotum portion pain, penis portion calculus can touch swollen thing at painful area, while firmly urinating, calculus can be discharged.Block completely acute urinary retention occurs, accompanying infection person's urethra has purulent secretion.Female urethra diverticulum calculus is mainly lower urinary tract infection symptom, has frequent micturition, urodynia, frequent urination at night, pyuria and hematuria, and sexual anhedonia is outstanding symptom, sometimes has urethra evacuation of pus; In male urethra diverticulum, calculus also can occur below penis that except urethra has secretions and dysurea one increases and harder swollen thing gradually, has obvious tenderness but blocks symptom without urinating.
Male anterior urethra calculus can touch calculus at penis or perineal position, and rear calculus of urethra can touch by per rectum.Female patient transvaginal can touch calculus and diverticulum, and x-ray is taken the photograph sheet can show calculus shade, and urethra metal bougie has special sensation and the sound, and calculus can be directly observed in urethroscope; Urine sediments analyzer cytolgical examination is one of content of uropsammus examination.Uropsammus examination refers to microscope the sediment thing of centrifugal rear urine checked, in the Urine sediments analyzer thing of physiology or pathology, visible component mainly contains cell, various cast, crystallization, antibacterial and parasite, tumor cell.The general character inspection of uropsammus examination and urine, chemical examination can complement one another, reference; The inspection of Urine sediments analyzer cast is one of content of uropsammus examination.Cast is that protein condenses and forms in renal tubules, and urine occurs that cast is generally the evidence of excess of the kidney matter pathological changes, in the process of its formation, if contain cell, is cellular cast; As containing degeneration cell debris, be granular cast; If fatty is fatty cast; Urine sediments analyzer crystallization inspection is one of content of uropsammus examination.
At present treatment calculus of urethra is mainly to take operative treatment and Drug therapy as main, expenses of surgical treatment is high, dangerous large, and Drug therapy takes effect slow, easily recurrence after curing, calculus of urethra has been brought great misery and inconvenience to patient, have a strong impact on their live and work, for studying a kind of medicine that can thoroughly cure calculus of urethra, become one of main object of each hospital's research.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of calculus of urethra; The selected medical material compatibility of medicine of the present invention is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and thering is the effect of regulating qi to disperse stagnation, Tonglin Paishi, antiinflammatory diuresis, wind-expelling pain-stopping, the symptoms such as frequent micturition, urodynia, frequent urination at night, pyuria and hematuria that treatment calculus of urethra is caused have unique curative effect, taking convenience, safe and reliable, have no side effect, non-relapse after healing, for treatment calculus of urethra determined curative effect, can reach the object for the treatment of both the principal and secondary aspects of a disease, clinic wide popularization and application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for calculus of urethra, raw material composition and the parts by weight of making described effective ingredient are:
23~47 parts of 26~50 parts of Flos Rosae Laevigataes of 38~62 parts of Herba Damnacanthi of 39~63 parts of Folium et cacumen sabinae chinensis of 41~65 portions of Herba Pteridis Multifidaes of 44~68 parts of Herba Phyllanthi Urinariaes of 46~70 parts of Herba aeginetiae indicae of 47~71 portions of Radix Gomphostemmaes of Herba Eichhorniae, 30~54 portions of Radix cocculi laurifoliis of 31~55 parts of Herba Hieracii Umbellatis of 31~55 portions of Herba Equiseti Arvinsiss of 33~57 parts of Herba Eragrostidis pilosaees of 35~59 portions of Juniperus rigida Sieb.et Zucc. of 35~59 parts of Cortex Clausenae Excavataes of 36~60 parts of Leontopodium leontopodioides (Willd.) Beauv. of 38~62 parts of close flowers and plants.
Raw material composition and the parts by weight of making described effective ingredient are:
27~43 parts of 30~46 parts of Flos Rosae Laevigataes of 42~58 parts of Herba Damnacanthi of 43~59 parts of Folium et cacumen sabinae chinensis of 45~61 portions of Herba Pteridis Multifidaes of 48~64 parts of Herba Phyllanthi Urinariaes of 50~66 parts of Herba aeginetiae indicae of 51~67 portions of Radix Gomphostemmaes of Herba Eichhorniae, 34~50 portions of Radix cocculi laurifoliis of 35~51 parts of Herba Hieracii Umbellatis of 35~51 portions of Herba Equiseti Arvinsiss of 37~53 parts of Herba Eragrostidis pilosaees of 39~55 portions of Juniperus rigida Sieb.et Zucc. of 39~55 parts of Cortex Clausenae Excavataes of 40~56 parts of Leontopodium leontopodioides (Willd.) Beauv. of 42~58 parts of close flowers and plants.
Raw material composition and the parts by weight of making described effective ingredient are:
31~39 parts of 34~42 parts of Flos Rosae Laevigataes of 46~54 parts of Herba Damnacanthi of 47~55 parts of Folium et cacumen sabinae chinensis of 49~57 portions of Herba Pteridis Multifidaes of 52~60 parts of Herba Phyllanthi Urinariaes of 54~62 parts of Herba aeginetiae indicae of 55~63 portions of Radix Gomphostemmaes of Herba Eichhorniae, 38~46 portions of Radix cocculi laurifoliis of 39~47 parts of Herba Hieracii Umbellatis of 39~47 portions of Herba Equiseti Arvinsiss of 41~49 parts of Herba Eragrostidis pilosaees of 43~51 portions of Juniperus rigida Sieb.et Zucc. of 43~51 parts of Cortex Clausenae Excavataes of 44~52 parts of Leontopodium leontopodioides (Willd.) Beauv. of 46~54 parts of close flowers and plants.
Raw material composition and the parts by weight of making described effective ingredient are:
35 parts of 38 parts of Flos Rosae Laevigataes of 50 parts of Herba Damnacanthi of 51 parts of Folium et cacumen sabinae chinensis of 53 portions of Herba Pteridis Multifidaes of 56 parts of Herba Phyllanthi Urinariaes of 58 parts of Herba aeginetiae indicae of 59 portions of Radix Gomphostemmaes of Herba Eichhorniae, 42 portions of Radix cocculi laurifoliis of 43 parts of Herba Hieracii Umbellatis of 43 portions of Herba Equiseti Arvinsiss of 45 parts of Herba Eragrostidis pilosaees of 47 portions of Juniperus rigida Sieb.et Zucc. of 47 parts of Cortex Clausenae Excavataes of 48 parts of Leontopodium leontopodioides (Willd.) Beauv. of 50 parts of close flowers and plants.
Treat a preparation method for the medicine of calculus of urethra, comprise following processing step:
(1) Herba Eichhorniae, Radix Gomphostemmae, Herba aeginetiae indicae, Folium et cacumen sabinae chinensis, Herba Damnacanthi, close flowers and plants, Leontopodium leontopodioides (Willd.) Beauv., Juniperus rigida Sieb.et Zucc., Herba Eragrostidis pilosae and Flos Rosae Laevigatae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) Herba Phyllanthi Urinariae is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(3) Herba Pteridis Multifidae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, standby;
(4) Cortex Clausenae Excavatae, Herba Equiseti Arvinsis, Herba Hieracii Umbellati and Radix cocculi laurifolii are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.15 is standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, juice and fine powder are mixed, make tablet, obtain the medicine for the treatment of calculus of urethra of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Eichhorniae: acrid in the mouth, light, cool in nature.Dispelling wind and heat pathogens, relieving stranguria by diuresis, heat-clearing and toxic substances removing.Main anemopyretic cold, edema, pyretic stranguria, lithangiuria, rubella, eczema, furuncle and phyma.< < Guangxi medicine is planted register > > and is carried: " refreshing and detoxicating, dehumidifying, the heat of dispeling the wind.External application herpes simplex.”
Radix Gomphostemmae: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, relieving cough and resolving phlegm, antiinflammatory diuresis.Control pneumonia, tracheobronchitis, cough with copious phlegm, urinary tract infection, cystitis, oedema due to nephritis, lithangiuria.
Herba aeginetiae indicae: bitter in the mouth, cool in nature, slightly poisonous.Removing toxic substances and promoting subsidence of swelling, clearing away heat and cooling blood.For tonsillitis, pharyngolaryngitis, urinary tract infection, osteomyelitis; Venom is controlled in external, furuncle.The doctor < < of Soviet Union Chinese herbal medicine handbook > > carries: " heat-clearing and toxic substances removing.Treating tonsillitis, pharyngolaryngitis, urinary tract infection.”
Herba Phyllanthi Urinariae: lightly seasoned, property is flat.Calming liver and clearing heat, promoting diuresis to remove toxic substance.Control enteritis, dysentery, infectious hepatitis, oedema due to nephritis, urinary tract infection, infantile malnutrition, acute catarrhal conjunctivitis corneal nebula, aphtha head sore, innominate toxic swelling.The < < SHENGCAO property of medicine is standby wants > > to carry: " control disorder of infantile eyes due to malnutrition, infantile malnutrition, pot meat or decoct washing." " controls that the upper raw skin ulcer son of head is in heaps, and sufferings difficulty is supported, and decocts washing, grinds out oil into powder and puts on the skin and also can.”
Herba Pteridis Multifidae: lightly seasoned, micro-hardship, cold in nature; Return large intestine, the heart, Liver Channel.Clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication; Traumatic hemorrhage is controlled in external, burn and scald.< < Guangxi medicine is planted will > > and is carried: " clear large intestine, lung-heat.Control hot bloody dysentery and toothache, emesis blood.”
Herba Damnacanthi: sweet in the mouth, hardship, property is flat.Expelling wind and removing dampness, promoting blood circulation and detumescence.Control gout, rheumatic arthralgia.Cough due to fluid-retention, lung abscess, edema, mass in the abdomen, jaundice, women's amenorrhea, infantile malnutrition, urticaria, traumatic injury.The conventional Chinese herbal medicine handbook > > of the < < of Guangzhou army carries: " inducing diuresis to remove edema, promoting blood circulation to remove blood stasis.Treating acute and chronic hepatitis, spleen enlargement.”
Folium et cacumen sabinae chinensis: acrid in the mouth, hardship, warm in nature, mild toxicity.Expelling wind and cold, promoting blood circulation and detoxication.Control anemofrigid cold, rheumatic arthritis, urticaria, toxic swelling from the beginning of.< < Fujian traditional herbal medicine > > carries: " parasite killing dirt eliminating, powder detoxifcation.Control urticaria, scleroma toxic swelling from the beginning of.”
Close flowers and plants: sweet in the mouth, cool in nature.Heat-clearing and toxic substances removing.Main urinary tract infection, carbuncle furuncle, stomatitis.
Leontopodium leontopodioides (Willd.) Beauv.: mildly bitter flavor, cold in nature.Heat clearing away, removing heat from blood, diuresis.For acute nephritis.Modern medicine study confirms.Leontopodium leontopodioides (Willd.) Beauv. has certain effect to eliminating albuminuria and hematuria.
Cortex Clausenae Excavatae: bitter in the mouth, micro-pungent, warm in nature; Return kidney, lung, urinary bladder channel.Expelling wind and cold, promoting the circulation of QI to relieve pain, dehumidifying detumescence.Cure mainly cold, fever, malaria, stomachache, edema, rheumatic arthritis.Fracture is controlled in external, bruise, eczema.< < Yunnan Chinese herbal medicine selects > > to carry: " dispelling wind to relieve the exterior syndrome, promoting the circulation of QI to relieve pain, preventing the attack (or recurrence) of malaria, parasite killing.Control sense, influenza, malaria, stomachache.”
Juniperus rigida Sieb.et Zucc.: sweet in the mouth, hardship, property is flat.The analgesia of dispeling the wind, dehumidifying diuresis.Main rheumatic arthritis, gout, nephritis, edema, urinary tract infection, formula is with still controlling brucellosis.
Herba Eragrostidis pilosae: sweet in the mouth, light, cool in nature.Inducing diuresis for treating stranguria syndrome, heat clearing and blood circulation promoting.Main pyretic stranguria, stranguria caused by urinary stone, conjunctival congestion is itched bitterly, traumatic injury.The conventional Chinese herbal medicine handbook > > in < < northeast carries: " cure mainly urinary tract infection, pyelonephritis.”
Herba Equiseti Arvinsis: bitter in the mouth, cool in nature, nontoxic; Return lung, stomach, Liver Channel.Clearing away heat and cooling blood, cough-relieving diuresis.Control haematemesis, epistaxis, has blood in stool, vicarious menstruation, cough and asthma, gonorrhea.< < Shaanxi Chinese herbal medicine > > carries: " clearing away heat and promoting diuresis, hemostasis, detumescence.Control urinary tract infection, difficulty and pain in micturition, fracture, epistaxis, spitting of blood, enterorrhagia, menorrhagia.”
Herba Hieracii Umbellati: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing, dampness removing removing food stagnancy.For carbuncle furuncle, urinary tract infection, the long-pending piece of stomachache, dysentery.< < Zhiwu Mingshi Tukao > > carries: " wash toxic swelling.”
Radix cocculi laurifolii: bitter in the mouth, pungent, cold in nature.Wind-expelling pain-stopping, inducing diuresis to remove edema, removing toxic substances, blood pressure lowering.For rheumatic arthritis, intercostal neuralgia, acute nephritis, urinary tract infection, hypertension, rheumatic heart disease, edema; Venom is controlled in external.
Flos Rosae Laevigatae: sour in the mouth, puckery, property is flat, nontoxic; Return lung, kidney, large intestine channel.Astringing intestine to stop diarrhea controlling nocturnal emission with astringent drugs, reducing urination leukorrhagia stopping, parasite killing.Main chronic diarrhea chronic dysentery, seminal emission, frequent micturition, leukorrhagia, cestode, ascarid, pinworm disease, early whitening of beard and hair.The modern Practical Chinese medicinal > of < < > carries: " control seminal emission, the enuresis, frequent micturition, chronic diarrhea rushes down, and chronic weak property sweating due to debility goes out, and married woman's endometritis secretion leukorrhagia.”
The present invention compared with prior art, has following beneficial effect:
1, the selected medical material compatibility of medicine of the present invention is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and taking convenience is safe and reliable, has no side effect, and non-relapse after healing, for treatment calculus of urethra determined curative effect, can reach the object for the treatment of both the principal and secondary aspects of a disease.
2, medicine of the present invention has the effect of regulating qi to disperse stagnation, Tonglin Paishi, antiinflammatory diuresis, wind-expelling pain-stopping, and the symptoms such as frequent micturition, urodynia, frequent urination at night, pyuria and hematuria that treatment calculus of urethra is caused have unique curative effect, clinic wide popularization and application.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
The close flowers and plants 56g of Herba Eichhorniae 67g Radix Gomphostemmae 66g Herba aeginetiae indicae 64g Herba Phyllanthi Urinariae 61g Herba Pteridis Multifidae 59g Folium et cacumen sabinae chinensis 58g Herba Damnacanthi 58g Leontopodium leontopodioides (Willd.) Beauv. 55g Cortex Clausenae Excavatae 55g Juniperus rigida Sieb.et Zucc. 53g Herba Eragrostidis pilosae 51g Herba Equiseti Arvinsis 51g Herba Hieracii Umbellati 50g Radix cocculi laurifolii 46g Flos Rosae Laevigatae 43g.
Treat a preparation method for the medicine of calculus of urethra, comprise following processing step:
(1) Herba Eichhorniae, Radix Gomphostemmae, Herba aeginetiae indicae, Folium et cacumen sabinae chinensis, Herba Damnacanthi, close flowers and plants, Leontopodium leontopodioides (Willd.) Beauv., Juniperus rigida Sieb.et Zucc., Herba Eragrostidis pilosae and Flos Rosae Laevigatae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) Herba Phyllanthi Urinariae is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(3) Herba Pteridis Multifidae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, standby;
(4) Cortex Clausenae Excavatae, Herba Equiseti Arvinsis, Herba Hieracii Umbellati and Radix cocculi laurifolii are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.15 is standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, juice and fine powder are mixed, make tablet, obtain the medicine for the treatment of calculus of urethra of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 10 days, be 1 course for the treatment of, can fully recover 3~4 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
The close flowers and plants 52g of Herba Eichhorniae 63g Radix Gomphostemmae 62g Herba aeginetiae indicae 60g Herba Phyllanthi Urinariae 57g Herba Pteridis Multifidae 55g Folium et cacumen sabinae chinensis 54g Herba Damnacanthi 54g Leontopodium leontopodioides (Willd.) Beauv. 51g Cortex Clausenae Excavatae 51g Juniperus rigida Sieb.et Zucc. 49g Herba Eragrostidis pilosae 47g Herba Equiseti Arvinsis 47g Herba Hieracii Umbellati 46g Radix cocculi laurifolii 42g Flos Rosae Laevigatae 39g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
The close flowers and plants 48g of Herba Eichhorniae 59g Radix Gomphostemmae 58g Herba aeginetiae indicae 56g Herba Phyllanthi Urinariae 53g Herba Pteridis Multifidae 51g Folium et cacumen sabinae chinensis 50g Herba Damnacanthi 50g Leontopodium leontopodioides (Willd.) Beauv. 47g Cortex Clausenae Excavatae 47g Juniperus rigida Sieb.et Zucc. 45g Herba Eragrostidis pilosae 43g Herba Equiseti Arvinsis 43g Herba Hieracii Umbellati 42g Radix cocculi laurifolii 38g Flos Rosae Laevigatae 35g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is: the close flowers and plants 44g of Herba Eichhorniae 55g Radix Gomphostemmae 54g Herba aeginetiae indicae 52g Herba Phyllanthi Urinariae 49g Herba Pteridis Multifidae 47g Folium et cacumen sabinae chinensis 46g Herba Damnacanthi 46g Leontopodium leontopodioides (Willd.) Beauv. 43g Cortex Clausenae Excavatae 43g Juniperus rigida Sieb.et Zucc. 41g Herba Eragrostidis pilosae 39g Herba Equiseti Arvinsis 39g Herba Hieracii Umbellati 38g Radix cocculi laurifolii 34g Flos Rosae Laevigatae 31g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is: the close flowers and plants 40g of Herba Eichhorniae 51g Radix Gomphostemmae 50g Herba aeginetiae indicae 48g Herba Phyllanthi Urinariae 45g Herba Pteridis Multifidae 43g Folium et cacumen sabinae chinensis 42g Herba Damnacanthi 42g Leontopodium leontopodioides (Willd.) Beauv. 39g Cortex Clausenae Excavatae 39g Juniperus rigida Sieb.et Zucc. 37g Herba Eragrostidis pilosae 35g Herba Equiseti Arvinsis 35g Herba Hieracii Umbellati 34g Radix cocculi laurifolii 30g Flos Rosae Laevigatae 27g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of calculus of urethra, select the routine clinical observation of calculus of urethra patient 124 make a definite diagnosis, patient to be divided at random two groups for the treatment of group and matched groups, treatment group 62 examples, male's 32 examples wherein, women's 30 examples, 27~48 years old age, 37.5 years old mean age, average course of disease 1.5 years; Matched group 62 examples, male's 31 examples wherein, women's 31 examples, 26~47 years old age, 36.5 years old mean age, average course of disease 1.3 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 10 days, be 1 course for the treatment of, can fully recover 2~3 courses for the treatment of, and the person of being in a bad way follows the doctor's advice and drinks the amount of adding.
Matched group is taken compound recipe money grass particle, take after mixing it with hot water, one time 1~2 bag, 3 times on the one, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: the clinical symptoms such as the dysuria that calculus of urethra causes, trouble urinating, pain all disappear, and calculus is got rid of completely, and physical recovery is normal.
(2) effective: clinical symptoms obviously alleviates, calculus obviously diminishes, and health takes a turn for the better to some extent.
(3) effective: clinical symptoms alleviates to some extent, and calculus diminishes to some extent, and health is clearly better.
(4) invalid: by treating rear clinical symptoms, have no improvement, calculus is unchanged.
4, result:
Select in the treatment group of medicine of the present invention, cure 68 examples, effective 31 examples, effective 23 examples, invalid 2 examples, cure rate 54.8%, total effective rate 98.4%.
In matched group, cure 32 examples, effective 21 examples, effective 15 examples, invalid 56 examples, cure rate 25.8%, total effective rate 54.8%.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is given an example:
1, Cai, female, 28 years old, Tianjin Jin Nan people.Patient is prone to the symptoms such as frequent micturition, urgent micturition at night, will last lavatory about 10 minutes, after remove examination in hospital, find trouble calculus of urethra, through doctor, recommend to take Drug therapy of the present invention, take after 1 course for the treatment of, symptom takes a turn for the better to some extent, continues to take after 1 course for the treatment of transference cure, recovery from illness, follows up a case by regular visits to so far not recurrence.
2, fourth, man, 33 years old, people was contained in Chongqing ten thousand.Patient often treats with courtesy, caused the daily life system time of patient's confusion, originally thought own youth, such life there is not harm to health, patient occurs frequently existing dysuria that good times don't last long, because paroxysmal dysuria causes patient to suffer from abdominal pain, be promptly admitted to hospital unbearably afterwards, take Drug therapy of the present invention, take medicine of the present invention after 1 course for the treatment of, symptom takes a turn for the better to some extent, continue to take medicine of the present invention after 1 course for the treatment of, transference cure, follows up a case by regular visits to after 1 year without recurrence.
3, go into business certain, female, 45 years old, people from Fushun.Patient's urethra has secretions and dysurea, and hematuria is with heating, whole body joint aches, remove hospital admission, check and draw calculus of urethra, used several different methods treatment, have no any improvement, to our hospital after being introduced, take Drug therapy of the present invention, take after 1 course for the treatment of, symptom obviously alleviates, continue to take after 1 course for the treatment of, transference cure, follows up a case by regular visits to after half a year without recurrence.
4, Wei, man, 35 years old, people from Baicheng, Jilin.Patient suffers from rear calculus of urethra, the multiple calculus of left ureter hypomere, right ureter epimere calculus and right renal calculus, like this intensive calculus hospitalization of having to, doctor advised takes out these calculus by operation, but because patient body reason has to abandon operative treatment, so rear doctor advised is taken Drug therapy of the present invention, to take after 1 course for the treatment of, symptom is clearly better, continue to take after 2 courses for the treatment of recovery from illness.
5, Xue, female, 41 years old, people from Hengshui, Hebei.Patient, because of nearest a period of time dysurea and dysuria, when having dysurea at first, does not take notice of, thinking after a while will be good, and the state of an illness had no improvement and increased the weight of on the contrary in the past one day one day time, before remove hospital admission, finally be defined as calculus of urethra, take Drug therapy of the present invention, take after 1 course for the treatment of, symptom is clearly better, take medicine of the present invention after 2 courses for the treatment of, transference cure, follows up a case by regular visits to after 1 year without recurrence.
6, leaf, man, 30 years old, Distributions in Liaocheng of Shandong Province people.Patient always has the symptom of urgent micturition dysurea recently, while starting to occur symptom, does not take notice of, think all right after a while, can the state of an illness more and more serious, just go to see a doctor and check treatment, be diagnosed as calculus of urethra, patient takes Drug therapy of the present invention, take after 1 course for the treatment of, urgent micturition dysurea symptom takes a turn for the better to some extent, takes after 2 courses for the treatment of, urgent micturition dysurea transference cure, recovery from illness.

Claims (5)

1. a medicine for the treatment of calculus of urethra, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
41~65 parts of 44~68 parts of Herba Phyllanthi Urinariaes of 46~70 parts of Herba aeginetiae indicae of 47~71 portions of Radix Gomphostemmaes of Herba Eichhorniae
36~60 parts of 38~62 parts of close flowers and plants of 38~62 parts of Herba Damnacanthi of 39~63 parts of Folium et cacumen sabinae chinensis of Herba Pteridis Multifidae
31~55 parts of 33~57 parts of Herba Eragrostidis pilosaees of 35~59 portions of Juniperus rigida Sieb.et Zucc. of 35~59 parts of Cortex Clausenae Excavataes of Leontopodium leontopodioides (Willd.) Beauv.
23~47 parts of 26~50 parts of Flos Rosae Laevigataes of 30~54 portions of Radix cocculi laurifoliis of 31~55 parts of Herba Hieracii Umbellatis of Herba Equiseti Arvinsis.
2. a kind of medicine for the treatment of calculus of urethra according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
45~61 parts of 48~64 parts of Herba Phyllanthi Urinariaes of 50~66 parts of Herba aeginetiae indicae of 51~67 portions of Radix Gomphostemmaes of Herba Eichhorniae
40~56 parts of 42~58 parts of close flowers and plants of 42~58 parts of Herba Damnacanthi of 43~59 parts of Folium et cacumen sabinae chinensis of Herba Pteridis Multifidae
35~51 parts of 37~53 parts of Herba Eragrostidis pilosaees of 39~55 portions of Juniperus rigida Sieb.et Zucc. of 39~55 parts of Cortex Clausenae Excavataes of Leontopodium leontopodioides (Willd.) Beauv.
27~43 parts of 30~46 parts of Flos Rosae Laevigataes of 34~50 portions of Radix cocculi laurifoliis of 35~51 parts of Herba Hieracii Umbellatis of Herba Equiseti Arvinsis.
3. a kind of medicine for the treatment of calculus of urethra according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
49~57 parts of 52~60 parts of Herba Phyllanthi Urinariaes of 54~62 parts of Herba aeginetiae indicae of 55~63 portions of Radix Gomphostemmaes of Herba Eichhorniae
44~52 parts of 46~54 parts of close flowers and plants of 46~54 parts of Herba Damnacanthi of 47~55 parts of Folium et cacumen sabinae chinensis of Herba Pteridis Multifidae
39~47 parts of 41~49 parts of Herba Eragrostidis pilosaees of 43~51 portions of Juniperus rigida Sieb.et Zucc. of 43~51 parts of Cortex Clausenae Excavataes of Leontopodium leontopodioides (Willd.) Beauv.
31~39 parts of 34~42 parts of Flos Rosae Laevigataes of 38~46 portions of Radix cocculi laurifoliis of 39~47 parts of Herba Hieracii Umbellatis of Herba Equiseti Arvinsis.
4. a kind of medicine for the treatment of calculus of urethra according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
53 parts of 56 parts of Herba Phyllanthi Urinariaes of 58 parts of Herba aeginetiae indicae of 59 portions of Radix Gomphostemmaes of Herba Eichhorniae
48 parts of 50 parts of close flowers and plants of 50 parts of Herba Damnacanthi of 51 parts of Folium et cacumen sabinae chinensis of Herba Pteridis Multifidae
43 parts of 45 parts of Herba Eragrostidis pilosaees of 47 portions of Juniperus rigida Sieb.et Zucc. of 47 parts of Cortex Clausenae Excavataes of Leontopodium leontopodioides (Willd.) Beauv.
35 parts of 38 parts of Flos Rosae Laevigataes of 42 portions of Radix cocculi laurifoliis of 43 parts of Herba Hieracii Umbellatis of Herba Equiseti Arvinsis.
5. as described in claim 1~4 any one, treat a preparation method for the medicine of calculus of urethra, it is characterized in that: comprise following processing step:
(1) Herba Eichhorniae, Radix Gomphostemmae, Herba aeginetiae indicae, Folium et cacumen sabinae chinensis, Herba Damnacanthi, close flowers and plants, Leontopodium leontopodioides (Willd.) Beauv., Juniperus rigida Sieb.et Zucc., Herba Eragrostidis pilosae and Flos Rosae Laevigatae are cleaned, put into container, add the distilled water of 8~10 times of amounts, soak after 5~6 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 60 ℃, relative density is 1.10~1.13, standby;
(2) Herba Phyllanthi Urinariae is cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(3) Herba Pteridis Multifidae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, standby;
(4) Cortex Clausenae Excavatae, Herba Equiseti Arvinsis, Herba Hieracii Umbellati and Radix cocculi laurifolii are cleaned, immersed 80% the alcohol solution dipping 1~2 hour of 5 times of amounts, heating extraction 3 hours, reclaims ethanol, filters, and obtains filtrate, and the thick paste that at 65 ℃ of simmer down tos, relative density is 1.12~1.15 is standby;
(5) above-mentioned steps (1)~(4) prepared thick paste, juice and fine powder are mixed, make tablet, obtain the medicine for the treatment of calculus of urethra of the present invention.
CN201410169466.4A 2014-04-25 2014-04-25 Medicine for treating urethral calculus and preparation method thereof Pending CN103920044A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971221A (en) * 2015-08-10 2015-10-14 孙霞 Traditional Chinese medicine for treating lithiasis in urinary system
CN105079534A (en) * 2015-08-17 2015-11-25 哈尔滨膳宝酒业有限公司 Drymaria cordata wine capable of inducing diuresis and relaxing bowels and preparation method thereof
CN105999015A (en) * 2016-07-30 2016-10-12 李若龙 Traditional Chinese medicine preparation for treating urethral stone and preparation method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1911256A (en) * 2005-08-09 2007-02-14 王啟江 Medicine for dispelling dampness, removing stone and apocatastasis, and its prepn. method
CN102671027A (en) * 2012-05-26 2012-09-19 吴新旺 Traditional Chinese medicine for curing calculi in urinary system
CN102949613A (en) * 2012-11-20 2013-03-06 西安福安创意咨询有限责任公司 Health-care product particle for treating urinary calculus and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1911256A (en) * 2005-08-09 2007-02-14 王啟江 Medicine for dispelling dampness, removing stone and apocatastasis, and its prepn. method
CN102671027A (en) * 2012-05-26 2012-09-19 吴新旺 Traditional Chinese medicine for curing calculi in urinary system
CN102949613A (en) * 2012-11-20 2013-03-06 西安福安创意咨询有限责任公司 Health-care product particle for treating urinary calculus and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104971221A (en) * 2015-08-10 2015-10-14 孙霞 Traditional Chinese medicine for treating lithiasis in urinary system
CN105079534A (en) * 2015-08-17 2015-11-25 哈尔滨膳宝酒业有限公司 Drymaria cordata wine capable of inducing diuresis and relaxing bowels and preparation method thereof
CN105999015A (en) * 2016-07-30 2016-10-12 李若龙 Traditional Chinese medicine preparation for treating urethral stone and preparation method

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Application publication date: 20140716