CN101801460A - 尿酸氧化酶用于治疗或预防由局部缺血或再灌注事件引起的心脏疾病或间接后遗症的用途 - Google Patents

尿酸氧化酶用于治疗或预防由局部缺血或再灌注事件引起的心脏疾病或间接后遗症的用途 Download PDF

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Publication number
CN101801460A
CN101801460A CN200880105379A CN200880105379A CN101801460A CN 101801460 A CN101801460 A CN 101801460A CN 200880105379 A CN200880105379 A CN 200880105379A CN 200880105379 A CN200880105379 A CN 200880105379A CN 101801460 A CN101801460 A CN 101801460A
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CN
China
Prior art keywords
urate oxidase
purposes
medicine
ischemia
uric acid
Prior art date
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Pending
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CN200880105379A
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English (en)
Chinese (zh)
Inventor
W·林茨
M·舍费尔
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Sanofi Aventis France
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Sanofi Aventis France
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Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Publication of CN101801460A publication Critical patent/CN101801460A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C12N9/0046—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/03—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with oxygen as acceptor (1.7.3)
    • C12Y107/03003—Factor-independent urate hydroxylase (1.7.3.3), i.e. uricase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CN200880105379A 2007-09-05 2008-08-20 尿酸氧化酶用于治疗或预防由局部缺血或再灌注事件引起的心脏疾病或间接后遗症的用途 Pending CN101801460A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP07291072 2007-09-05
EP07291072.2 2007-09-05
US1524007P 2007-12-20 2007-12-20
US61/015,240 2007-12-20
PCT/EP2008/006858 WO2009030373A1 (en) 2007-09-05 2008-08-20 Use of urate oxidase for the treatment or prophylaxis of disorders or indirect sequelae of the heart caused by ischemic or reperfusion events

Publications (1)

Publication Number Publication Date
CN101801460A true CN101801460A (zh) 2010-08-11

Family

ID=38713162

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880105379A Pending CN101801460A (zh) 2007-09-05 2008-08-20 尿酸氧化酶用于治疗或预防由局部缺血或再灌注事件引起的心脏疾病或间接后遗症的用途

Country Status (22)

Country Link
US (1) US20100266567A1 (https=)
EP (1) EP2197550A1 (https=)
JP (1) JP2011509920A (https=)
KR (1) KR20100053609A (https=)
CN (1) CN101801460A (https=)
AR (1) AR068360A1 (https=)
AU (1) AU2008295145B2 (https=)
BR (1) BRPI0816406A2 (https=)
CA (1) CA2697929A1 (https=)
CL (1) CL2008002623A1 (https=)
CO (1) CO6260090A2 (https=)
IL (1) IL204259A (https=)
MA (1) MA31624B1 (https=)
MX (1) MX2010001976A (https=)
MY (1) MY183770A (https=)
NZ (1) NZ583635A (https=)
PA (1) PA8794801A1 (https=)
PE (1) PE20090642A1 (https=)
TW (1) TW200927929A (https=)
UY (1) UY31320A1 (https=)
WO (1) WO2009030373A1 (https=)
ZA (1) ZA201000774B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020019360A1 (en) * 2000-06-28 2002-02-14 Merck & Co., Inc. Treatment for cardiovascular disease
WO2004026118A2 (en) * 2002-09-20 2004-04-01 Oregon Health & Science University Administration of free radical scavengers to prevent or treat ischemia-reperfusion injuries
WO2005077042A2 (en) * 2004-02-09 2005-08-25 Human Genome Sciences, Inc. Albumin fusion proteins
US20050232902A1 (en) * 2004-04-17 2005-10-20 Theodoros Kofidis Injectable bioartificial tissue matrix

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114972A (en) * 1990-07-30 1992-05-19 Tsuyoshi Ohnishi Synthesis and uses of new ascorbic acid derivatives which have anti-oxidant and anti-cancer activities
US20070197512A1 (en) * 2006-01-27 2007-08-23 Japan Tobacco Inc. Carboxylic Acid Compounds and Use Thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020019360A1 (en) * 2000-06-28 2002-02-14 Merck & Co., Inc. Treatment for cardiovascular disease
WO2004026118A2 (en) * 2002-09-20 2004-04-01 Oregon Health & Science University Administration of free radical scavengers to prevent or treat ischemia-reperfusion injuries
WO2005077042A2 (en) * 2004-02-09 2005-08-25 Human Genome Sciences, Inc. Albumin fusion proteins
US20050232902A1 (en) * 2004-04-17 2005-10-20 Theodoros Kofidis Injectable bioartificial tissue matrix

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SUSUMU WATANABE ET.AL.: "Reducing uric acid as a means to prevent cardiovascular and renal disease", 《EXPERT OPINION ON THERAPEUTIC PATENTS》 *

Also Published As

Publication number Publication date
TW200927929A (en) 2009-07-01
EP2197550A1 (en) 2010-06-23
NZ583635A (en) 2011-06-30
MA31624B1 (fr) 2010-08-02
MY183770A (en) 2021-03-12
CA2697929A1 (en) 2009-03-12
WO2009030373A1 (en) 2009-03-12
MX2010001976A (es) 2010-03-10
PE20090642A1 (es) 2009-06-18
UY31320A1 (es) 2009-04-30
AU2008295145B2 (en) 2013-12-05
RU2010112867A (ru) 2011-10-10
ZA201000774B (en) 2011-04-28
PA8794801A1 (es) 2009-04-23
CO6260090A2 (es) 2011-03-22
KR20100053609A (ko) 2010-05-20
US20100266567A1 (en) 2010-10-21
BRPI0816406A2 (pt) 2017-05-16
CL2008002623A1 (es) 2009-01-16
JP2011509920A (ja) 2011-03-31
AR068360A1 (es) 2009-11-11
AU2008295145A1 (en) 2009-03-12
IL204259A (en) 2013-06-27

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