CN101796418B - 检测分析人体脓毒症的方法 - Google Patents

检测分析人体脓毒症的方法 Download PDF

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Publication number
CN101796418B
CN101796418B CN2008801058553A CN200880105855A CN101796418B CN 101796418 B CN101796418 B CN 101796418B CN 2008801058553 A CN2008801058553 A CN 2008801058553A CN 200880105855 A CN200880105855 A CN 200880105855A CN 101796418 B CN101796418 B CN 101796418B
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psp
reg
day
antibody
sepsis
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Chinese (zh)
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CN101796418A (zh
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罗尔夫·格拉夫
丹尼尔·比姆勒
马里厄斯·基尔
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Zurich Universitaet Institut fuer Medizinische Virologie
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Zurich Universitaet Institut fuer Medizinische Virologie
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/474—Pancreatic thread protein; Reg protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN2008801058553A 2007-09-07 2008-09-02 检测分析人体脓毒症的方法 Active CN101796418B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07017539.3 2007-09-07
EP07017539 2007-09-07
PCT/EP2008/007158 WO2009030456A1 (en) 2007-09-07 2008-09-02 Method for assaying sepsis in humans

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CN101796418A CN101796418A (zh) 2010-08-04
CN101796418B true CN101796418B (zh) 2013-05-01

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US (2) US8435755B2 (enExample)
EP (1) EP2185937B2 (enExample)
JP (1) JP5048838B2 (enExample)
CN (1) CN101796418B (enExample)
AT (1) ATE514950T1 (enExample)
AU (1) AU2008295046B2 (enExample)
CA (1) CA2696319C (enExample)
DK (1) DK2185937T4 (enExample)
ES (1) ES2368877T5 (enExample)
NZ (1) NZ583474A (enExample)
PL (1) PL2185937T5 (enExample)
PT (1) PT2185937E (enExample)
WO (1) WO2009030456A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2577316T3 (en) * 2010-05-31 2017-05-08 Univ Hospital Of Basel Procedure for testing for lower respiratory tract infections or inflammation
WO2012028594A1 (en) 2010-08-31 2012-03-08 Otto-Von-Guericke-Universität Magdeburg Method for assaying peritonitis in humans
US20130004968A1 (en) * 2010-09-22 2013-01-03 Robert Webber Sepsis blood biomarker system
WO2014009480A1 (en) 2012-07-12 2014-01-16 Universität Zürich Method for assaying sepsis and outcome in humans by detection of psp/reg
WO2014068018A1 (en) * 2012-10-30 2014-05-08 Abbott Gmbh & Co.Kg Methods of prognosis and diagnosis of sepsis
WO2014117165A1 (en) * 2013-01-28 2014-07-31 Vanderbilt University Method for differentiating sepsis and systemic inflammatory response syndrome (sirs)
EP2813852A3 (en) 2013-06-11 2015-03-25 University Of Zurich Method for detecting the development of an infection in humans
CN106367488A (zh) * 2016-08-29 2017-02-01 北京泱深生物信息技术有限公司 Letmd1在脓毒症诊断中的应用
EP3438668A1 (en) 2017-08-04 2019-02-06 B.R.A.H.M.S GmbH Diagnosis and risk stratification of fungal infections
WO2019053118A1 (en) 2017-09-13 2019-03-21 B.R.A.H.M.S Gmbh PROADRÉNOMÉDULLINE AS A MARKER OF ABNORMAL PLATELET RATES
EP3502706A1 (en) 2017-12-20 2019-06-26 B.R.A.H.M.S GmbH Workflow for risk assessment and patient management using procalcitonin and midregional-proadrenomedullin
CN108181472B (zh) * 2018-03-05 2020-07-21 吉林大学 昆虫细胞表达psp为校准品的检测psp试剂盒
EP3578989A1 (en) * 2018-06-06 2019-12-11 B.R.A.H.M.S GmbH Pro-adm for prognosis of trauma-related complications in polytrauma patients
FR3087338B1 (fr) 2018-10-22 2020-10-09 Amadeite Extrait d'algues pour son utilisation pour le traitement ou la prevention de l'immunosuppression post-traumatique
CA3196464A1 (en) * 2020-11-03 2022-05-12 Nicolas Durand Method for assessing the severity of sars
US20250020663A1 (en) * 2021-11-25 2025-01-16 Abionic Sa Method for the management of antibiotic administration

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000561A1 (en) * 1996-06-28 1998-01-08 Zeneca Limited Reg gene expression in cancer tissue

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
EP0378924B1 (en) 1988-12-21 1996-11-13 The General Hospital Corporation Detection of neurological disease or dysfunction
DE50105971D1 (de) * 2001-12-04 2005-05-25 Brahms Ag Verfahren zur Diagnose von Sepsis unter Bestimmung von CA 125
EP1318405B1 (de) 2001-12-04 2004-11-17 B.R.A.H.M.S Aktiengesellschaft Verfahren zur Diagnose von Sepsis unter Bestimmung löslicher Cytokeratinfragmente
DE50103032D1 (de) 2001-12-04 2004-09-02 Brahms Ag Verfahren zur Diagnose von Sepsis unter Bestimmung von CA 19-9
DE50103030D1 (de) 2001-12-04 2004-09-02 Brahms Ag Verfahren zur Diagnose von Sepsis unter Bestimmung von S100B
DE10228103A1 (de) 2002-06-24 2004-01-15 Bayer Cropscience Ag Fungizide Wirkstoffkombinationen
JP2004194534A (ja) * 2002-12-17 2004-07-15 Sumitomo Pharmaceut Co Ltd 炎症性腸疾患疾患マーカーおよびその利用
EP1581812B1 (en) * 2003-01-06 2008-07-16 Wyeth Compositions and methods for diagnosing and treating colon cancers
WO2004087874A2 (en) * 2003-03-28 2004-10-14 Nuvelo, Inc. Novel nucleic acids and polypeptides
US20070224638A1 (en) 2006-03-27 2007-09-27 Institut Pasteur Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections
DK2577316T3 (en) * 2010-05-31 2017-05-08 Univ Hospital Of Basel Procedure for testing for lower respiratory tract infections or inflammation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000561A1 (en) * 1996-06-28 1998-01-08 Zeneca Limited Reg gene expression in cancer tissue

Also Published As

Publication number Publication date
CN101796418A (zh) 2010-08-04
CA2696319A1 (en) 2009-03-12
PL2185937T5 (pl) 2014-12-31
AU2008295046B2 (en) 2013-08-01
CA2696319C (en) 2021-02-02
PL2185937T3 (pl) 2012-02-29
PT2185937E (pt) 2011-09-06
US20100222223A1 (en) 2010-09-02
DK2185937T4 (da) 2014-10-20
US9857381B2 (en) 2018-01-02
DK2185937T3 (da) 2011-09-12
ATE514950T1 (de) 2011-07-15
AU2008295046A1 (en) 2009-03-12
EP2185937B1 (en) 2011-06-29
JP2010538282A (ja) 2010-12-09
US20130203612A1 (en) 2013-08-08
ES2368877T3 (es) 2011-11-23
US8435755B2 (en) 2013-05-07
EP2185937B2 (en) 2014-07-16
ES2368877T5 (es) 2014-10-20
NZ583474A (en) 2011-07-29
JP5048838B2 (ja) 2012-10-17
WO2009030456A1 (en) 2009-03-12
EP2185937A1 (en) 2010-05-19

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