CN101796014A - 多不饱和脂肪酸酯的制备和纯化 - Google Patents

多不饱和脂肪酸酯的制备和纯化 Download PDF

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Publication number
CN101796014A
CN101796014A CN200880104965A CN200880104965A CN101796014A CN 101796014 A CN101796014 A CN 101796014A CN 200880104965 A CN200880104965 A CN 200880104965A CN 200880104965 A CN200880104965 A CN 200880104965A CN 101796014 A CN101796014 A CN 101796014A
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CN
China
Prior art keywords
composition
acid
polyunsaturated fatty
esters
ester
Prior art date
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Pending
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CN200880104965A
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English (en)
Chinese (zh)
Inventor
克里什纳·拉曼
李祯洙
尼尔·莱宁格
克里斯·卢加特
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DSM IP Assets BV
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Martek Biosciences Corp
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Publication of CN101796014A publication Critical patent/CN101796014A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
    • A—HUMAN NECESSITIES
    • A21—BAKING; EDIBLE DOUGHS
    • A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
    • A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
    • A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
    • A21D2/14—Organic oxygen compounds
    • A21D2/16—Fatty acid esters
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/60—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Fats And Perfumes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN200880104965A 2007-06-29 2008-06-27 多不饱和脂肪酸酯的制备和纯化 Pending CN101796014A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94728407P 2007-06-29 2007-06-29
US60/947,284 2007-06-29
PCT/US2008/068613 WO2009006317A1 (en) 2007-06-29 2008-06-27 Production and purification of esters of polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
CN101796014A true CN101796014A (zh) 2010-08-04

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880104965A Pending CN101796014A (zh) 2007-06-29 2008-06-27 多不饱和脂肪酸酯的制备和纯化

Country Status (8)

Country Link
US (3) US20090023808A1 (enExample)
EP (1) EP2173699A4 (enExample)
JP (1) JP2010532418A (enExample)
CN (1) CN101796014A (enExample)
AU (2) AU2008269989B2 (enExample)
CA (1) CA2692355C (enExample)
MX (2) MX2010000263A (enExample)
WO (1) WO2009006317A1 (enExample)

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CN102843913A (zh) * 2010-02-17 2012-12-26 邦奇油类公司 十八碳四烯酸的油组合物
CN104394702A (zh) * 2012-05-29 2015-03-04 罗盖特兄弟公司 用于不断富集由微藻产生的、具有dha乙酯的一种油的方法
WO2016058284A1 (zh) * 2014-10-13 2016-04-21 浙江医药股份有限公司新昌制药厂 一种甘油酯型多不饱和脂肪酸的制备方法
CN105779123A (zh) * 2014-08-06 2016-07-20 石家庄搏澳增塑材料科技有限公司 一种富集不饱和脂肪酸甲酯的清洁工艺
CN108289470A (zh) * 2015-10-05 2018-07-17 帝斯曼知识产权资产管理有限公司 油组合物和制备方法
CN105848748B (zh) * 2013-12-11 2018-07-24 诺瓦塞普工艺公司 脂肪酸的色谱纯化方法
CN109337939A (zh) * 2018-09-30 2019-02-15 河北康睿达脂质有限公司 一种多不饱和脂肪酸结构脂质的制备方法
CN111164067A (zh) * 2017-08-07 2020-05-15 帝斯曼知识产权资产管理有限公司 用于产生浓缩的多不饱和脂肪酸油的过程
TWI706727B (zh) * 2018-06-21 2020-10-11 澳大利亞商努賽德私人有限公司 基於植物之脂質組合物、包括該組合物之類藥劑營養品組合物、包括該組合物之食品、以及用於產生該組合物之方法
CN112533483A (zh) * 2018-06-21 2021-03-19 纽希得私人有限公司 Dha富集的多不饱和脂肪酸组合物
TWI774898B (zh) * 2018-06-21 2022-08-21 美商努賽德營養美國股份有限公司 基於植物之脂質組合物、包含該脂質組合物之油漆或清漆，及用於產生該脂質組合物的方法
TWI774896B (zh) * 2018-06-21 2022-08-21 美商努賽德營養美國股份有限公司 基於植物之脂質組合物及其用途、包含該脂質組合物之類藥劑營養品組合物及食品以及產生該脂質組合物脂之方法

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