CN101766571B - 一种头孢匹胺/苯甲酸钠/碳酸氢钠药物组合物脂质体注射剂 - Google Patents
一种头孢匹胺/苯甲酸钠/碳酸氢钠药物组合物脂质体注射剂 Download PDFInfo
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- CN101766571B CN101766571B CN2010101063796A CN201010106379A CN101766571B CN 101766571 B CN101766571 B CN 101766571B CN 2010101063796 A CN2010101063796 A CN 2010101063796A CN 201010106379 A CN201010106379 A CN 201010106379A CN 101766571 B CN101766571 B CN 101766571B
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- Prior art keywords
- cefpiramide
- liposome
- sodium
- sodium bicarbonate
- sodium benzoate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229960005446 cefpiramide Drugs 0.000 title claims abstract description 91
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 title claims abstract description 66
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- 229910000030 sodium bicarbonate Inorganic materials 0.000 title claims abstract description 33
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- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- XPFJYKARVSSRHE-UHFFFAOYSA-K trisodium;2-hydroxypropane-1,2,3-tricarboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].[Na+].OC(=O)CC(O)(C(O)=O)CC(O)=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O XPFJYKARVSSRHE-UHFFFAOYSA-K 0.000 description 1
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