CN101759629A - 西他沙星中间体的新的制备方法 - Google Patents
西他沙星中间体的新的制备方法 Download PDFInfo
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- CN101759629A CN101759629A CN200910259671A CN200910259671A CN101759629A CN 101759629 A CN101759629 A CN 101759629A CN 200910259671 A CN200910259671 A CN 200910259671A CN 200910259671 A CN200910259671 A CN 200910259671A CN 101759629 A CN101759629 A CN 101759629A
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- azaspiro
- amino
- oxo
- heptane
- styroyl
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
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- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2009102596719A CN101759629B (zh) | 2009-12-22 | 2009-12-22 | 西他沙星中间体的制备方法 |
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CN2009102596719A CN101759629B (zh) | 2009-12-22 | 2009-12-22 | 西他沙星中间体的制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN101759629A true CN101759629A (zh) | 2010-06-30 |
CN101759629B CN101759629B (zh) | 2012-01-11 |
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CN2009102596719A Expired - Fee Related CN101759629B (zh) | 2009-12-22 | 2009-12-22 | 西他沙星中间体的制备方法 |
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CN (1) | CN101759629B (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102093152A (zh) * | 2010-11-19 | 2011-06-15 | 中南大学 | 一种拆分手性药物的方法 |
CN103012198A (zh) * | 2011-09-21 | 2013-04-03 | 中国药科大学 | 光学活性环状化合物的制备方法 |
CN103435523A (zh) * | 2013-08-13 | 2013-12-11 | 苏州楚凯药业有限公司 | (1r,2s)-2-氟-环丙胺对甲苯磺酸盐的制备方法 |
CN105330590A (zh) * | 2015-10-15 | 2016-02-17 | 广州盈雅药业有限公司 | 西他沙星五元环侧链中间体的制备方法 |
CN105439939A (zh) * | 2015-11-12 | 2016-03-30 | 四川恒康科技发展有限公司 | 一种(S)-N-Boc-3-羟基哌啶的合成方法 |
US10358417B2 (en) | 2016-05-06 | 2019-07-23 | Chen-Stone (Guangzhou) Co., Ltd. | Method for preparing efficiently synthetic sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl tert-butyl carbamate |
CN110483369A (zh) * | 2019-09-12 | 2019-11-22 | 广州康瑞泰药业有限公司 | 合成(7s)-5-氮杂螺[2.4]庚烷-7-基氨基甲酸叔丁酯的方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2663044C (en) * | 2006-10-06 | 2012-07-24 | Bausch & Lomb Incorporated | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same |
FR2916446B1 (fr) * | 2007-05-24 | 2009-08-21 | Biocodex Sa | Nouveau procede de synthese de fluoroquinolones |
CN101497612A (zh) * | 2009-03-03 | 2009-08-05 | 北京华禧联合科技发展有限公司 | 一类新喹诺酮类化合物及其制备与用途 |
-
2009
- 2009-12-22 CN CN2009102596719A patent/CN101759629B/zh not_active Expired - Fee Related
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102093152A (zh) * | 2010-11-19 | 2011-06-15 | 中南大学 | 一种拆分手性药物的方法 |
CN102093152B (zh) * | 2010-11-19 | 2013-04-03 | 中南大学 | 一种拆分手性药物的方法 |
CN103012198A (zh) * | 2011-09-21 | 2013-04-03 | 中国药科大学 | 光学活性环状化合物的制备方法 |
CN103435523A (zh) * | 2013-08-13 | 2013-12-11 | 苏州楚凯药业有限公司 | (1r,2s)-2-氟-环丙胺对甲苯磺酸盐的制备方法 |
CN103435523B (zh) * | 2013-08-13 | 2015-12-23 | 苏州楚凯药业有限公司 | (1r,2s)-2-氟-环丙胺对甲苯磺酸盐的制备方法 |
CN105330590A (zh) * | 2015-10-15 | 2016-02-17 | 广州盈雅药业有限公司 | 西他沙星五元环侧链中间体的制备方法 |
CN105330590B (zh) * | 2015-10-15 | 2018-09-25 | 广州市朗启医药科技有限责任公司 | 西他沙星五元环侧链中间体的制备方法 |
CN105439939A (zh) * | 2015-11-12 | 2016-03-30 | 四川恒康科技发展有限公司 | 一种(S)-N-Boc-3-羟基哌啶的合成方法 |
CN105439939B (zh) * | 2015-11-12 | 2018-12-04 | 四川恒康科技发展有限公司 | 一种(S)-N-Boc-3-羟基哌啶的合成方法 |
US10358417B2 (en) | 2016-05-06 | 2019-07-23 | Chen-Stone (Guangzhou) Co., Ltd. | Method for preparing efficiently synthetic sitafloxacin intermediate (7S)-5-azaspiro[2.4]heptane-7-yl tert-butyl carbamate |
CN110483369A (zh) * | 2019-09-12 | 2019-11-22 | 广州康瑞泰药业有限公司 | 合成(7s)-5-氮杂螺[2.4]庚烷-7-基氨基甲酸叔丁酯的方法 |
Also Published As
Publication number | Publication date |
---|---|
CN101759629B (zh) | 2012-01-11 |
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ASS | Succession or assignment of patent right |
Owner name: FOUNDER PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD Free format text: FORMER OWNER: FOUNDER PHARMACEUTICAL RESEARCH INSTITUTE CO., LTD. |
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Effective date of registration: 20110817 Address after: 100871 Beijing, Haidian District Road, building No. 298, founder of the building, Zhongguancun, layer 5 Applicant after: Peking Founder Group Co., Ltd. Co-applicant after: PKUCare Pharmaceutical R&D Center Co-applicant after: PKU International Healthcare Group Co., Ltd. Address before: 100871 No. 298, Fu Cheng Road, Beijing, Haidian District Applicant before: Peking Founder Group Co., Ltd. Co-applicant before: PKUCare Pharmaceutical R&D Center |
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C14 | Grant of patent or utility model | ||
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120111 Termination date: 20171222 |
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CF01 | Termination of patent right due to non-payment of annual fee |