CN101744899B - Traditional Chinese medicine paste for treating chemotherapy phlebitis vasospasm stage and preparation - Google Patents

Traditional Chinese medicine paste for treating chemotherapy phlebitis vasospasm stage and preparation Download PDF

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Publication number
CN101744899B
CN101744899B CN2008102496082A CN200810249608A CN101744899B CN 101744899 B CN101744899 B CN 101744899B CN 2008102496082 A CN2008102496082 A CN 2008102496082A CN 200810249608 A CN200810249608 A CN 200810249608A CN 101744899 B CN101744899 B CN 101744899B
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vasospasm
chinese medicine
stage
preparation
traditional chinese
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CN101744899A (en
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冯曰珍
高丽红
贾荣娟
侯春华
李林倩
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Feng Yuezhen
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冯曰珍
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Abstract

The invention relates to a traditional Chinese medicine paste for treating a chemotherapy phlebitis vasospasm stage and preparation. The traditional Chinese medicine paste is characterized by comprising the following ingredients by weight portion: 15-20 portions of radices paeoniae rubra, 15-20 portions of radices paeoniae alba, 15-20 portions of liquorice, 15-20 portions of frankincense and 15-20 portions of myrrh. The preparation method of the traditional Chinese medicine paste for treating the chemotherapy phlebitis vasospasm stage is characterized by comprising the following steps: taking the ingredients according to the weight portion to be prepared into superfine power, uniformly mixing, adding the superfine power in melted Vaseline by a ratio of 1 to 4-5, and stirring. The traditional Chinese medicine paste for treating the chemotherapy phlebitis vasospasm stage and the preparation have the advantages of easy material selection, convenient preparation, low cost, no side effect, 79.4% of cure rate and 100% of efficiency, and can be widely applied to clinics.

Description

A kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage
Technical field
The invention belongs to the Chinese materia medica technical field, be specifically related to a kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage.
Background technology
Chemotherapy is treatment malignant tumor one of effective method the most, and chemotherapeutic phlebitis is the main local untoward reaction of chemotherapy, and incidence rate is up to 57.6%.Though the method for existing report treatment chemotherapeutic phlebitis has a lot; But its common feature is in phlebitic whole pathology evolution process; Only with single prescription treatment; Take corresponding countermeasures, so effect is undesirable, also not effective especially at present medicine according to the different pathological change of each phase of chemotherapeutic phlebitis.
Summary of the invention
The object of the present invention is to provide a kind of defective that can overcome the prior art existence; And effective percentage up to 100%, cure rate reaches 79.4%, selection easily, a kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage of convenient, the cost of preparation.
According to phlebitic pathogeny; Vasospasm stage mainly due to quiet or the quiet big medicine of concentration height, zest and long-term quiet mechanical stimulus blood vessel wall repeatedly of pushing away, make changes such as local pH value, metabolism and osmotic pressure, cytolysis; Lysosome breaks; Discharge inflammatory mediator, make the vascular smooth muscle spasm, and vasospasm property pain occurs.Chinese medicine promoting blood circulation to remove blood stasis of the present invention, spasmolytic, pain relieving, promotion blood behavior therapy principle alleviate local excitation, and anti-wall of vein continues undermined, prevent the pathology progress, reduce the phlebitis incidence rate.
A kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage is characterized in that according to weight proportion raw material comprises following component: 15 ~ 20 parts of Radix Paeoniae Rubra, 15 ~ 20 parts of the Radix Paeoniae Albas, 15 ~ 20 parts in Radix Glycyrrhizae, 15 ~ 20 parts of Olibanums, 15 ~ 20 parts of Myrrhas; Described a kind of manufacture method of treating the Chinese medicine unguentum of chemotherapy phlebitis vasospasm stage; It is characterized in that may further comprise the steps: get each component medicine by weight ratio and be developed into the superfines mix homogeneously, the ratio in 1: 4 ~ 5 adds superfines to stir in the vaseline that has dissolved to be processed.
Method for using: evenly smear one deck Chinese medicine unguentum with aseptic cotton carrier, scope is moved towards long 8~10cm from puncture vein both sides 3~4cm along vein, every day 3 times, for three days on end.
A kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage of the present invention, said Radix Paeoniae Rubra: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, contained paeonol and glucoside ability antiinflammatory, spasmolytic, calmness, analgesic, antibacterial.The Radix Paeoniae Alba: expand peripheral blood vessel through the smooth muscle spasmolysis contraction, increase circulation volume, alleviate blood vessel irriate again, prevent or reduce phlebitic generation, and calmness, analgesic activity are arranged.Radix Glycyrrhizae: can detoxify, kind again heat clearing away can also be in harmonious proportion the Radix Paeoniae Alba to give birth to curative effect.Contained glycyrrhizin, enoxolone have 17-hydroxy-11-dehydrocorticosterone appearance antiinflammatory action.Contained liquiritigenin, isoliquiritin unit and FM 100Smooth muscle there is spasmolysis, FM 100Analgesic activity is arranged.Olibanum, Myrrha: promoting blood circulation to remove blood stasis, detumescence, analgesic effect are good, are drug for invigorating blood circulation and eliminating stasis, but but to the stasis of blood not only dissipating blood stasis but also pain relieving of having a pain that stagnate, the blood vessel wall of damaged are had reducing swelling and alleviating pain, putrefaction-removing granulation-promoting effect.
The synthetic Synergistic treatment of all medicines: to remove smooth muscle spasm, alleviate and the elimination Crampy Pain, promote blood circulation, alleviate local excitation, anti-wall of vein continues undermined, prevents pathology to make progress, thereby reaches the purpose that reduces the phlebitis incidence rate.
The specific embodiment
Embodiment 1: a kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage, according to weight proportion, raw material comprises following component: 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 15 parts in Radix Glycyrrhizae, 15 parts of Olibanums, 15 parts of Myrrhas.The manufacture method of said Chinese medicine unguentum is: get each component medicine by weight ratio and clean and to dry, being ground into granular size is 50 microns powder, mix well in the vaseline that ultra-fine medicated powder adding has been dissolved by 1: 4 ratio.
Embodiment 2: a kind of Chinese medicine unguentum and preparation of treating chemotherapy phlebitis vasospasm stage, according to weight proportion, raw material comprises following component: 20 parts of Radix Paeoniae Rubra, 20 parts of the Radix Paeoniae Albas, 20 parts in Radix Glycyrrhizae, 20 parts of Olibanums, 20 parts of Myrrhas.The manufacture method of said Chinese medicine unguentum is: get each component medicine by weight ratio and clean and to dry, being ground into granular size is 50 microns powder, mix well in the vaseline that ultra-fine medicated powder adding has been dissolved by 1: 5 ratio.
Therapeutic effect:
Criterion of therapeutical effect: a kind of curative effect of treating the Chinese medicine unguentum of chemotherapy phlebitis vasospasm stage judges mainly whether disappear according to the vasospasm pain.Medication 3 days was a course of treatment.Concrete curative effect is divided following three grades: cure----vasospasm pain and all disappear; Produce effects----vasospasm pain obviously alleviates; Invalid----vasospasm has no to disappear bitterly.
Effect: chemotherapeutic phlebitis be vasospasm stage to treat 68 routine patients in early days with this prescription, wherein cure 54 examples, produce effects 68 examples, cure rate 79.4%, effective percentage 100%.

Claims (2)

1. a Chinese medicine unguentum of treating chemotherapy phlebitis vasospasm stage is characterized in that according to weight proportion, and crude drug is following component: 15~20 parts of Radix Paeoniae Rubra, 15~20 parts of the Radix Paeoniae Albas, 15~20 parts in Radix Glycyrrhizae, 15~20 parts of Olibanums, 15~20 parts of Myrrhas; Its preparation method is: get each component medicine by weight ratio and be developed into the superfines mix homogeneously, the ratio in 1: 4~5 adds superfines to stir in the vaseline that has dissolved to be processed.
2. method for preparing of treating the Chinese medicine unguentum of chemotherapy phlebitis vasospasm stage according to claim 1; It is characterized in that may further comprise the steps: get each component medicine by weight ratio and be developed into the superfines mix homogeneously, the ratio in 1: 4~5 adds superfines to stir in the vaseline that has dissolved to be processed.
CN2008102496082A 2008-12-18 2008-12-18 Traditional Chinese medicine paste for treating chemotherapy phlebitis vasospasm stage and preparation Expired - Fee Related CN101744899B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102008684B (en) * 2010-11-14 2012-06-06 王爱华 Traditional Chinese medicine composition for curing level-IV chemotherapeutic phlebitis
CN105267684A (en) * 2015-11-25 2016-01-27 战士娟 Traditional Chinese medicine for treating chemotherapeutic phlebitis of tumor patients and preparation method thereof
CN105456794A (en) * 2015-12-30 2016-04-06 张云 Traditional Chinese medicine for treating chemotherapeutic phlebitis of tumor patient and preparation method thereof

Citations (3)

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CN1046414C (en) * 1993-03-04 1999-11-17 杨全力 Adhesive plaster for treatment of spur and its making method
CN1411875A (en) * 2002-12-06 2003-04-23 苏洪泉 Pain-alleviating apparatus
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CN1046414C (en) * 1993-03-04 1999-11-17 杨全力 Adhesive plaster for treatment of spur and its making method
CN1411875A (en) * 2002-12-06 2003-04-23 苏洪泉 Pain-alleviating apparatus
CN101002899A (en) * 2007-01-11 2007-07-25 许新华 Pure traditional Chinese medicine preparation for treating hemiparalysis

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王涛.活血通络膏外敷应用于化疗性静脉炎的临床研究.《张家口医学院学报》.2004,第21卷(第3期),25-26. *

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