CN1060787A - The reparation technology of red medicine plaster - Google Patents
The reparation technology of red medicine plaster Download PDFInfo
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- CN1060787A CN1060787A CN 91110956 CN91110956A CN1060787A CN 1060787 A CN1060787 A CN 1060787A CN 91110956 CN91110956 CN 91110956 CN 91110956 A CN91110956 A CN 91110956A CN 1060787 A CN1060787 A CN 1060787A
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- extractum
- radix angelicae
- red medicine
- medicine plaster
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Abstract
The present invention is a kind of reparation technology of red medicine plaster, it is characterized in that a certain amount of Radix Notoginseng, the Radix Angelicae Dahuricae, Eupolyphaga Seu Steleophaga, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami are added alcohol reflux makes extractum, again with the medicine and the substrate stirring and evenly mixing of extractum and a certain amount of Percutaneous absorption enhancer, Claritin, refrigerant, anti-inflammatory analgetic effect, and make red medicine plaster.The present invention has easy to use, and is rapid-action, and short treating period can be used with former tablet the patient with severe symptoms, and light patient can apply ointment or plaster the part, and curative effect is more seen characteristics such as special effect.Transdermal administration absorbs without Liver and kidney, can reduce toxicity to greatest extent, drug safety, the utilization rate of raising medicine.
Description
The invention belongs to the processing technique of Chinese herbs field, specifically a kind of production method of Chinese medicine plaster.
As everyone knows, by the history of existing more than ten years of Tabules of the red medicine of " Liaoning Province's drug standard " of the exclusive development of our factory.This medical instrument has the effect of promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, collateral dredging tissue regeneration promoting, is specially adapted to traumatic injury, muscles and bones is swollen and ache and disease such as far and near stasis of blood trouble, rheumatic numbness.Evident in efficacy, the cure rate height, and enjoy a good market both at home and abroad.But, the red medicine of this oral tablet dosage form is found in long-term practice, when the heavier and affected part of damage was far away, only by the general dose medication, treatment time can increase relatively, therefore can make the patient produce unnecessary stress, influence therapeutic effect,, also can increase the burden of Liver and kidney if strengthen dosage, even also can produce toxic and side effects, influence patient's physical and mental health.
The objective of the invention is to provide a kind of reparation technology of the red medicine plaster that cooperates the use of mercurochrome tablet agent dosage form or use separately for the therapeutic effect that improves red medicine.
The object of the present invention is achieved like this:
(1), with Radix Notoginseng, the Radix Angelicae Dahuricae, Eupolyphaga Seu Steleophaga, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami with 4.0-4.5: 1: 1: 1: 1: 1 weight ratio is broken mix after, with 90% alcohol reflux three times, add for the first time 4 times of amounts of ethanol, extracted 2 hours, second and third time adds 3 times of amounts of ethanol, and each extracted 1 hour, then through leave standstill, filtration, merging filtrate, reclaim ethanol, it is 1.3-1.4(40 ℃ that concentrating under reduced pressure is made relative density), account for the extractum of dispensing total amount (weight) 15-25%.
(2), the abundant stirring and evenly mixing of substrate that above-mentioned extractum and Borneolum Syntheticum, Camphora, wintergreen oil, Mentholum, Semen daturae fluid extract, chondroitin sulfate, diphhydramine hydrochloride, dimethyl sulfoxide, essence, carmine are doubly measured with its total amount 3.1-4.1 with the percentage by weight of 38.2-50.7%: 4.37-5.48%: 4.37-5.48%: 6.37-7.99%: 9.98-12.52%: 9.98-12.52%: 1.25-1.57%: 1.50-1.88%: 9.98-12.52%: 1.50-1.88%: 0-0.50% again, make coating, be coated with cream, cap seal, section, packing promptly.
Red medicine plaster of the present invention has following characteristics: easy to use, rapid-action, short treating period, can be used with former tablet the patient with severe symptoms, light patient can apply ointment or plaster the part, and curative effect is more seen special effect, transdermal administration absorbs without Liver and kidney, can reduce toxicity to greatest extent, drug safety improves the drug utilization degree.On former tablet basis, added Percutaneous absorption enhancer in addition, the medicine of Claritin, refrigerant, anti-inflammatory analgetic effect, antiallergic, anti-inflammatory analgetic effect have so just been strengthened, show through institute of materia medica, Liaoning Province pharmacology, pathology experimental result, every index has all reached domestic and international advanced level, has filled up the blank of red medicine exterior-applied formulation.
To be described in further detail the present invention by embodiment below.
Concrete technology of the present invention and prescription are:
(1), Radix Notoginseng 750 gram, the Radix Angelicae Dahuricae 175 grams, Eupolyphaga Seu Steleophaga 175 grams, Rhizoma Chuanxiong 175 grams, Radix Angelicae Sinensis 175 grams, Flos Carthami 175 grams are mixed after fragmentation, the alcohol reflux with 90% three times, add 4 times of amounts of ethanol the first time, extracted 2 hours; Second and third time adds 3 times of amounts of ethanol, each extracted 1 hour, then through leave standstill, filtration, merging filtrate, reclaim ethanol, it is 1.3-1.4(40 ℃ that concentrating under reduced pressure is made relative density) extractum, the weight of extractum account for the dispensing total amount optimum range be the extractum of 19-22%.
(2), will be dissolved in the substrate of mixing in the gasoline and making by rubber 720 grams, zinc oxide 928 grams, Colophonium 744 grams, vaseline 128 grams, lanoline 80 grams, liquid paraffin 20 grams, adding above-mentioned extractum and Borneolum Syntheticum 35 grams, Camphora 35 grams, wintergreen oil 51 grams, Mentholum 80 grams, Semen daturae fluid extract 80 grams, chondroitin sulfate 10 grams, diphhydramine hydrochloride 12 grams, dimethyl sulfoxide 80 grams, essence 12 grams, carmine mixes in right amount, stir, make coating, be coated with cream, lid lining, section, packing and be finished product.
Claims (3)
1, a kind of reparation technology of red medicine plaster is characterized in that:
(1), with Radix Notoginseng, the Radix Angelicae Dahuricae, Eupolyphaga Seu Steleophaga, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami with 4.0-4.5: 1: 1: 1: 1: 1 weight ratio is broken mix after, with 90% alcohol reflux three times, add for the first time 4 times of amounts of ethanol, extracted 2 hours, second and third time adds 3 times of amounts of ethanol, and each extracted 1 hour, then through leave standstill, filtration, merging filtrate, reclaim ethanol, it is 1.3-1.4 (40 ℃) that concentrating under reduced pressure is made relative density, account for the extractum of dispensing total amount (weight) 15-25%;
(2), the abundant stirring and evenly mixing of substrate that above-mentioned extractum and Borneolum Syntheticum, Camphora, wintergreen oil, Mentholum, Semen daturae fluid extract, chondroitin sulfate, diphhydramine hydrochloride, dimethyl sulfoxide, essence, carmine are doubly measured with its total amount 3.1-4.1 with the percentage by weight of 38.2-50.7%: 4.37-5.48%: 4.37-5.48%: 6.37-7.99%: 9.98-12.52%: 9.98-12.52%: 1.25-1.57%: 1.50-1.88%: 9.98-12.52%: 1.50-1.88%: 0-0.50% again, make coating, be coated with cream, cap seal, section, packing promptly.
2, the reparation technology of red medicine plaster according to claim 1 is characterized in that: the optimum weight ratio of Radix Notoginseng, the Radix Angelicae Dahuricae, Eupolyphaga Seu Steleophaga, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Flos Carthami is 30: 7: 7: 7: 7: 7; The optimum weight percentage ratio of extractum and Borneolum Syntheticum, Camphora, wintergreen oil, Mentholum, Semen daturae fluid extract, chondroitin sulfate, diphhydramine hydrochloride, dimethyl sulfoxide, essence, carmine is 45.14: 4.86: 4.86: 7.08: 11.11: 11.11: 1.39: 1.67: 11.11: 1.39: 0.28.
3, the reparation technology of red medicine plaster according to claim 1 is characterized in that: the optimum range that the weight of extractum accounts for the dispensing total amount is 19-22%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91110956 CN1060787A (en) | 1991-11-29 | 1991-11-29 | The reparation technology of red medicine plaster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91110956 CN1060787A (en) | 1991-11-29 | 1991-11-29 | The reparation technology of red medicine plaster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1060787A true CN1060787A (en) | 1992-05-06 |
Family
ID=4910367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 91110956 Pending CN1060787A (en) | 1991-11-29 | 1991-11-29 | The reparation technology of red medicine plaster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1060787A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1067874C (en) * | 1996-07-26 | 2001-07-04 | 广州卫生材料厂 | Traditional Chinese medicine plaster and its preparation method |
| CN1118280C (en) * | 1995-04-11 | 2003-08-20 | S·C·泰曼公司 | Bioactive concentrate, its producing method and certain drug compositions containing also chondroitin sulphate |
| CN1322871C (en) * | 2003-11-07 | 2007-06-27 | 唐俊琪 | Preparation of compound pseudo-ginseng drop pellets for treating traumatologic disease |
| CN1332686C (en) * | 2005-09-29 | 2007-08-22 | 沈阳中药制药有限公司 | Chinese medicine for treating tractures and preparation for making plaster thereof |
| CN101066290B (en) * | 2007-06-12 | 2011-04-20 | 白岩 | Hongyao ointment and its preparation |
| CN102743674A (en) * | 2012-07-19 | 2012-10-24 | 重庆陪都药业股份有限公司 | Chinese compound formula rheumatalgia-relieving plaster emplastrum |
| CN103006737A (en) * | 2012-10-16 | 2013-04-03 | 杨晓兵 | Oral liquid used for promoting blood circulation to remove meridian obstruction and preventing and treating osteoporosis |
| CN104225063A (en) * | 2013-06-19 | 2014-12-24 | 沈阳红药集团股份有限公司 | Hongyao Babu plaster and preparation method thereof |
| CN104116771B (en) * | 2014-07-24 | 2017-01-04 | 北京康远制药有限公司 | A kind of mercurochrome tablet with promoting blood circulation and stopping pain effect and preparation method thereof |
| CN111557962A (en) * | 2020-06-08 | 2020-08-21 | 沈阳红药集团股份有限公司 | Red medicine patch and preparation method thereof |
-
1991
- 1991-11-29 CN CN 91110956 patent/CN1060787A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1118280C (en) * | 1995-04-11 | 2003-08-20 | S·C·泰曼公司 | Bioactive concentrate, its producing method and certain drug compositions containing also chondroitin sulphate |
| CN1067874C (en) * | 1996-07-26 | 2001-07-04 | 广州卫生材料厂 | Traditional Chinese medicine plaster and its preparation method |
| CN1322871C (en) * | 2003-11-07 | 2007-06-27 | 唐俊琪 | Preparation of compound pseudo-ginseng drop pellets for treating traumatologic disease |
| CN1332686C (en) * | 2005-09-29 | 2007-08-22 | 沈阳中药制药有限公司 | Chinese medicine for treating tractures and preparation for making plaster thereof |
| CN101066290B (en) * | 2007-06-12 | 2011-04-20 | 白岩 | Hongyao ointment and its preparation |
| CN102743674A (en) * | 2012-07-19 | 2012-10-24 | 重庆陪都药业股份有限公司 | Chinese compound formula rheumatalgia-relieving plaster emplastrum |
| CN103006737A (en) * | 2012-10-16 | 2013-04-03 | 杨晓兵 | Oral liquid used for promoting blood circulation to remove meridian obstruction and preventing and treating osteoporosis |
| CN104225063A (en) * | 2013-06-19 | 2014-12-24 | 沈阳红药集团股份有限公司 | Hongyao Babu plaster and preparation method thereof |
| CN104225063B (en) * | 2013-06-19 | 2017-11-14 | 沈阳红药集团股份有限公司 | Red medicine Babu cream and preparation method thereof |
| CN104116771B (en) * | 2014-07-24 | 2017-01-04 | 北京康远制药有限公司 | A kind of mercurochrome tablet with promoting blood circulation and stopping pain effect and preparation method thereof |
| CN111557962A (en) * | 2020-06-08 | 2020-08-21 | 沈阳红药集团股份有限公司 | Red medicine patch and preparation method thereof |
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