CN1259940C - Medicinal composition for treatnig bone fracture - Google Patents

Medicinal composition for treatnig bone fracture Download PDF

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Publication number
CN1259940C
CN1259940C CN 200410069348 CN200410069348A CN1259940C CN 1259940 C CN1259940 C CN 1259940C CN 200410069348 CN200410069348 CN 200410069348 CN 200410069348 A CN200410069348 A CN 200410069348A CN 1259940 C CN1259940 C CN 1259940C
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radix
cortex
fracture
pharmaceutical composition
catechu
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CN 200410069348
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CN1586588A (en
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李焕忠
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Abstract

The present invention discloses a medical composition for treating fractures, which is composed of the following components: largeleaf gentian root, angelica, red peony root, erhuo, safflower, eucommia bark, akebia stem, catechu, pyrite, frankincense, myrrh, muskmelon seed, wolfberry bark, fortune's drynaria rhizome, sappan wood, common floweringquince fruit, slenderstyle acanthopanax bark, radix et rhizoma rhei from sichuan of china, silktree albizzia bark and liquoric root. The medical composition can be prepared into any suitable medicinal preparation according to a method through adding auxiliary materials in the field. The medical composition of the present invention can effectively treat various fractures and has the advantages of short treatment course and obvious effect.

Description

The medical composition and its use of treatment fracture
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of fracture, relating in particular to a kind of mainly is the pharmaceutical composition of raw material for treating fracture with the Chinese herbal medicine.
Background technology
Fracture blood trouble, the injury of the bone, as malpractice, early stage fracture can not be fully recovered, and can cause can not healing for a long time, causes the old bone does not connect, brings great misery to the patient.Methods such as the clinical main employing surgical operation of doctor trained in Western medicine, external and internal fixation are treated, though there are defectives such as cost is high, the patient suffering is big in instant effect.The traditional Chinese medical science adopts the external plaster agent to treat in conjunction with the method for innerwear Chinese medicine preparation more, used Chinese medicine preparation and emplastrum such as bone knitting powder, Cortex torricelliae tiliifoliae, bone-knitting capsule etc., though all have reducing swelling and alleviating pain, promote effect such as growth of spur, defective such as ubiquity taking effect in various degree is slow, the course of treatment is long.
Summary of the invention
The present invention seeks to overcome above prior art defective, the pharmaceutical composition of the high treatment fracture of a kind of instant effect, curative effect is provided.
The present invention seeks to realize by following scheme:
A kind of pharmaceutical composition for the treatment of fracture, form by each component of following weight portion:
Radix Gentianae Macrophyllae 2~8, Radix Angelicae Sinensis 2~8, Radix Paeoniae Rubra 2~8, two work 2~8, Flos Carthami 2~8, the Cortex Eucommiae 2~8, Caulis Akebiae 2~8, catechu 4~14, Pyritum 4~14, Olibanum 4~14, Myrrha 4~14, Semen Melo 4~14, Cortex Lycii 4~14, Rhizoma Drynariae 4~14, Lignum Sappan 4~14, Fructus Chaenomelis 4~14, Cortex Acanthopancis 4~14, Radix Et Rhizoma Rhei 4~14, Cortex Albiziae 1~4, Radix Glycyrrhizae 1~4.
A kind of pharmaceutical composition for the treatment of fracture, the weight portion scope of its each component is:
Radix Gentianae Macrophyllae 3~6, Radix Angelicae Sinensis 3~6, Radix Paeoniae Rubra 3~6, two work 3~6, Flos Carthami 3~6, the Cortex Eucommiae 3~6, Caulis Akebiae 3~6, catechu 6~10, Pyritum 6~10, Olibanum 6~10, Myrrha 6~10, Semen Melo 6~10, Cortex Lycii 6~10, Rhizoma Drynariae 6~10, Lignum Sappan 6~10, Fructus Chaenomelis 6~10, Cortex Acanthopancis 6~10, Radix Et Rhizoma Rhei 6~10, Cortex Albiziae 1~3, Radix Glycyrrhizae 1~3.
Preferably:
Radix Gentianae Macrophyllae 4, Radix Angelicae Sinensis 4, Radix Paeoniae Rubra 4, two work 4, Flos Carthami 4, the Cortex Eucommiae 4, Caulis Akebiae 4, catechu 8, Pyritum 8, Olibanum 8, Myrrha 8, Semen Melo 8, Cortex Lycii 8, Rhizoma Drynariae 8, Lignum Sappan 8, Fructus Chaenomelis 8, Cortex Acanthopancis 8, Radix Et Rhizoma Rhei 8, Cortex Albiziae 2, Radix Glycyrrhizae 2.
The present composition is based on research and the Therapeutic Principle thereof of medical science to fracture mechanism, simultaneously according to the pharmaceutical research achievement, filter out the natural plant of activating blood circulation to dissipate blood stasis, Repercusion analgesia, promotion growth of spur,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.
Compatibility of drugs foundation of the present invention:
Radix Gentianae Macrophyllae, Radix Angelicae Sinensis, Radix Paeoniae Rubra, two work, Flos Carthami, the Cortex Eucommiae, Caulis Akebiae have the effect of activating blood circulation to dissipate blood stasis; The effect of catechu, Pyritum, Olibanum, Myrrha, Semen Melo, Cortex Lycii, Rhizoma Drynariae, the pain relieving of Lignum Sappan tool, the healing of promotion callus; The effect of Fructus Chaenomelis, Cortex Acanthopancis, Radix Et Rhizoma Rhei's tool Qi-guiding and pain-killing; Cortex Albiziae, Radix Glycyrrhizae have the effect of the above-mentioned all medicine effects of mediation; More than each medicine compatibility together, mutually coordinate, the interaction energy of each drug effect performs to maximum, thereby can effectively cure all kinds of fracture.
The used herbal raw material of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
The preparation of Pyritum can prepare also directly therefrom pharmacy purchase with reference to method as described below: Pyritum all has distribution in the field, various places, all can gather throughout the year, with field acquisition to Pyritum clean up after, break into pieces and dry the back fine grinding, crossing 40~100 mesh sieves can be standby.
Pharmaceutical composition of the present invention can add adjuvant and be prepared into any appropriate drug preparation by the conventional method of this area, for example can be patch, tablet, capsule, pill, granule, powder, suspensoid, oral liquid etc.
Usage and consumption: dosage of the present invention depends on concrete dosage form, factors such as patient's age, body weight, health status.Medicine of the present invention can take orally or external, the also oral administration external of holding concurrently.As guidance: 1) for oral administration: with the capsule is example, and adult's consumption is to obey twice every day, obeys 6 at every turn, every content of dispersion 0.15g, and the child reduces by half, and yellow wine is for drawing, and warm water takes.2) external: take by weighing each component by described components by weight percent, each component is ground into fine powder, with 60 degree grain neutral spirits that the fine powder furnishing is thick, it is applied in the affected part, tie fixedly affected part of clamping plate that good back reuse willow makes with binder, changed a medicine every 3 days and get final product.
Pharmaceutical composition of the present invention all has significant curative effect for all types of fracture, for example tiltedly furcula folding, spiral fracture, greenstick fracture, comminuted fracture postoperative, transverse fracture etc. are fractured, cut to type, have instant effect, short treating period, advantage such as with low cost, can cure in average more than 40 days for old people's fracture, middle age can be cured in average more than 30 days, day can fully recover surplus the child 20.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never limit the scope of the invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight: Radix Gentianae Macrophyllae 40g, Radix Angelicae Sinensis 40g, Radix Paeoniae Rubra 40g, two 40g alive, Flos Carthami 40g, Cortex Eucommiae 40g, Caulis Akebiae 40g, catechu 80g, Pyritum 80g, Olibanum 80g, Myrrha 80g, Semen Melo 80g, Cortex Lycii 80g, Rhizoma Drynariae 80g, Lignum Sappan 80g, Fructus Chaenomelis 80g, Cortex Acanthopancis 80g, the 80g of Radix Et Rhizoma Rhei, Cortex Albiziae 20g, Radix Glycyrrhizae 20g.Above-mentioned each raw material is ground into fine powder to be incapsulated promptly.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight: Radix Gentianae Macrophyllae 70g, Radix Angelicae Sinensis 70g, Radix Paeoniae Rubra 70g, two 70g alive, Flos Carthami 70g, Cortex Eucommiae 70g, Caulis Akebiae 70g, catechu 130g, Pyritum 130g, Olibanum 130g, Myrrha 130g, Semen Melo 130g, Cortex Lycii 130g, Rhizoma Drynariae 130g, Lignum Sappan 130g, Fructus Chaenomelis 130g, Cortex Acanthopancis 130g, the 130g of Radix Et Rhizoma Rhei, Cortex Albiziae 40g, Radix Glycyrrhizae 40g.Above-mentioned each raw material is ground into fine powder, add ethanol and make adhesive, add starch and make filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material by following weight: Radix Gentianae Macrophyllae 30g, Radix Angelicae Sinensis 30g, Radix Paeoniae Rubra 30g, two 30g alive, Flos Carthami 30g, Cortex Eucommiae 30g, Caulis Akebiae 30g, catechu 60g, Pyritum 60g, Olibanum 60g, Myrrha 60g, Semen Melo 60g, Cortex Lycii 60g, Rhizoma Drynariae 60g, Lignum Sappan 60g, Fructus Chaenomelis 60g, Cortex Acanthopancis 60g, the 60g of Radix Et Rhizoma Rhei, Cortex Albiziae 15g, Radix Glycyrrhizae 15g.Above-mentioned each raw material is ground into fine powder, add adjuvant and make granule, and dry compacting in flakes promptly.
The clinical observation on the therapeutic effect test of [test example] medicine composite for curing fracture of the present invention
One, the physical data of subjects: adopt pharmaceutical composition of the present invention to treat 265 routine patients altogether, wherein male 172 examples, women 114 examples; The oldest person 76 years old, age reckling 8 years old: oblique type 68 examples of fracturing wherein, cut furcula and roll over 45 examples, spiral fracture 39 examples, greenstick fracture 43 examples, comminuted fracture postoperative 28 examples, transverse fracture 42 examples.
Two, Therapeutic Method: external application adds interior usefulness.External application: the weight portion ratio of each component of prescription takes by weighing each component in the by specification, each component is ground into fine powder, with 60 degree grain neutral spirits that the fine powder furnishing is thick, it is applied in the affected part, tie fixedly affected part of clamping plate that good back reuse willow makes with binder, changed a medicine every 3 days and get final product.For oral administration: the capsule that the embodiment of the invention is prepared, adult's consumption is to obey twice every day, obeys 6 at every turn, and the child reduces by half, and yellow wine is for drawing, and warm water takes.15 days is a course of treatment, treats 3 courses of treatment altogether.
Three, therapeutic outcome: among the 265 routine patients that treated, through the treatment of 3 courses of treatment, 228 examples of wherein fully recovering, produce effects 22 examples, effective 12 examples, invalid 3 examples, total effective rate reaches 98.8%.The result shows that pharmaceutical composition of the present invention not only can effectively be treated all kinds of fracture, and short treating period, instant effect.

Claims (6)

1, a kind of pharmaceutical composition for the treatment of fracture is characterized in that being made up of each component of following weight portion: Radix Gentianae Macrophyllae 2~8, Radix Angelicae Sinensis 2~8, Radix Paeoniae Rubra 2~8, two work 2~8, Flos Carthami 2~8, the Cortex Eucommiae 2~8, Caulis Akebiae 2~8, catechu 4~14, Pyritum 4~14, Olibanum 4~14, Myrrha 4~14, Semen Melo 4~14, Cortex Lycii 4~14, Rhizoma Drynariae 4~14, Lignum Sappan 4~14, Fructus Chaenomelis 4~14, Cortex Acanthopancis 4~14, Radix Et Rhizoma Rhei 4~14, Cortex Albiziae 1~4, Radix Glycyrrhizae 1~4.
2, pharmaceutical composition according to claim 1 is characterized in that the weight portion scope of each component is: Radix Gentianae Macrophyllae 3~6, Radix Angelicae Sinensis 3~6, Radix Paeoniae Rubra 3~6, two work 3~6, Flos Carthami 3~6, the Cortex Eucommiae 3~6, Caulis Akebiae 3~6, catechu 6~10, Pyritum 6~10, Olibanum 6~10, Myrrha 6~10, Semen Melo 6~10, Cortex Lycii 6~10, Rhizoma Drynariae 6~10, Lignum Sappan 6~10, Fructus Chaenomelis 6~10, Cortex Acanthopancis 6~10, Radix Et Rhizoma Rhei 6~10, Cortex Albiziae 1~3, Radix Glycyrrhizae 1~3.
3, pharmaceutical composition according to claim 1 is characterized in that the weight portion of each component is: Radix Gentianae Macrophyllae 4, Radix Angelicae Sinensis 4, Radix Paeoniae Rubra 4, two work 4, Flos Carthami 4, the Cortex Eucommiae 4, Caulis Akebiae 4, catechu 8, Pyritum 8, Olibanum 8, Myrrha 8, Semen Melo 8, Cortex Lycii 8, Rhizoma Drynariae 8, Lignum Sappan 8, Fructus Chaenomelis 8, Cortex Acanthopancis 8, Radix Et Rhizoma Rhei 8, Cortex Albiziae 2, Radix Glycyrrhizae 2.
4, pharmaceutical composition according to claim 1, the dosage form that it is characterized in that this pharmaceutical composition are patch, tablet, capsule, pill, granule, powder, suspensoid or oral liquid.
5, the purposes of the described pharmaceutical composition of claim 1 in preparation treatment fracture medicine.
6, purposes according to claim 5, wherein said fracture are oblique type fracture, cut furcula folding, spiral fracture, greenstick fracture, comminuted fracture postoperative or transverse fracture.
CN 200410069348 2004-07-19 2004-07-19 Medicinal composition for treatnig bone fracture Expired - Fee Related CN1259940C (en)

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CN 200410069348 CN1259940C (en) 2004-07-19 2004-07-19 Medicinal composition for treatnig bone fracture

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CN1259940C true CN1259940C (en) 2006-06-21

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CN104258238A (en) * 2014-10-23 2015-01-07 张相才 External application path for fracture patients and preparation method thereof

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