CN101724541B - Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue and preparation method thereof - Google Patents

Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue and preparation method thereof Download PDF

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CN101724541B
CN101724541B CN2008102015364A CN200810201536A CN101724541B CN 101724541 B CN101724541 B CN 101724541B CN 2008102015364 A CN2008102015364 A CN 2008102015364A CN 200810201536 A CN200810201536 A CN 200810201536A CN 101724541 B CN101724541 B CN 101724541B
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subsequent use
root
wine
raw material
medicine health
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CN101724541A (en
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陈保华
徐福莺
薛爱珍
谢松
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SHANGHAI LEIYUN PHARMACEUTICAL INDUSTRY Co Ltd
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SHANGHAI LEIYUN PHARMACEUTICAL INDUSTRY Co Ltd
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Abstract

The invention provides Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue, which is prepared from Chinese traditional medicine raw materials comprising radix pseudostellariae, rhodiola root, sealwort, the fruit of Chinese wolfberry, turtle shell, eucommia bark, cassia seed, lotus nut, kudzu root, bud of Chinese scholartree, radix angelicae, dangshen, Chinese angelica, prepared rhizome of rehmannia and edible auxiliary materials. The mouse functional experiment shows that the Chinese traditional medicine health-care wine has the functions of enhancing the immunity and relieving the physical fatigue. The Chinese traditional medicine health-care wine of the invention has a reasonable formula, is suitable for people with low immunity and easy fatigue, can be taken conveniently and has obvious effect and better application value. The invention also provides a preparation method.

Description

Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue and preparation method thereof
Technical field
The present invention relates to Chinese medicine and health food, be specifically related to Chinese medicine health-care wine (Lei Shi board big gun Paotianhongyangshejiu) of a kind of strengthening immunity and alleviating physical fatigue and preparation method thereof.
Background technology
Increase along with human living standard's raising with to the degree of concern of self health status, the trend that functional health wine rises gradually is irreversible.The future trend of wine industry is transformed to health promoting wine by common wine gradually; Pursue natural; Advocating healthy consumers demand is that people have the recurrence of blindly moving towards the rational faculty, and as a kind of health promoting wine with the China of accumulateing in the deep history culture, its market potential and potential consumer groups are very considerable.From functional health wine consumption situation, the consumption of health promoting wine accounts for drinks total quantity consumed 2% in the world.Because the service competition more and more fierce, people are also increasing for the pressure of feeling in the work; In addition, the influence of the factors such as change aspect mode of life and food habits causes immunity of organisms and fatigue resistance to descend.Therefore, people hope that can seek to obtain some from Chinese medicine helps Chinese medicine and health food particularly easy to use.Thus, the Chinese medicine health-care wine of exploitation strengthening immunity and alleviating physical fatigue becomes new goal in research.
Summary of the invention
The Chinese medicine health-care wine (Lei Shi board big gun Paotianhongyangshejiu) that the invention provides a kind of strengthening immunity and alleviating physical fatigue is made up of Chinese medicine and edible adjuvant.As Chinese medicine material of the present invention be: Root of Heterophylly Faalsestarwort, Root of Kirilow Rhodiola, sealwort, wolfberry fruit, turtle shell, the bark of eucommia, Semen Cassiae, lotus seeds, the root of kudzu vine, the sophora bud, the root of Dahurain angelica, Radix Codonopsis, Radix Angelicae Sinensis and cultivated land.Edible adjuvant is lyase agent, correctives and thinner.Wherein the lyase agent is bent wine or ethanol (containing alcohol amount 30% ± 2~50% ± 2); Correctives is sucrose, fructose or Xylitol; Thinner is a pure water.
Each components contents proportioning of Chinese medicine of the present invention and edible adjuvant sees the following form:
Medicinal material and auxiliary material Title The content proportioning
Medicinal material Root of Heterophylly Faalsestarwort 3.0~9.0(g)
Medicinal material Root of Kirilow Rhodiola 6.0~18.0(g)
Medicinal material Turtle shell 3.0~9.0(g)
Medicinal material The bark of eucommia 3.0~9.0(g)
Medicinal material The root of Dahurain angelica 1.0~3.0(g)
Medicinal material Semen Cassiae 3.0~9.0(g)
Medicinal material Wolfberry fruit 4.0~12.0(g)
Medicinal material Lotus seeds 2.0~6.0(g)
Medicinal material The root of kudzu vine 3.0~9.0(g)
Medicinal material The sophora bud 3.0~9.0(g)
Medicinal material Sealwort 5.0~15.0(g)
Medicinal material Radix Codonopsis 3.0~9.0(g)
Medicinal material Cultivated land 3.0~9.0(g)
Medicinal material Radix Angelicae Sinensis 3.0~9.0(g)
The lyase agent Bent wine, ethanol (containing alcohol amount 30% ± 2~50% ± 2) 900~3000(ml)
Correctives Sucrose, fructose or Xylitol 1.0~3.0% (v/v) of medicinal material total amount
Thinner Pure water 5.0~45.0(g)
These article select for use Root of Kirilow Rhodiola, the root of kudzu vine, Root of Heterophylly Faalsestarwort, turtle shell, the bark of eucommia, sealwort, the root of Dahurain angelica, Chinese yam, Semen Cassiae, wolfberry fruit, lotus seeds, Radix Codonopsis, cultivated land and Radix Angelicae Sinensis etc. to process for main raw material according to the Chinese medicine theory that takes care of health.Pass through its synergy, can reach function of enhancing immunity and alleviating physical fatigue function, the raising body is to the adaptive faculty of internal and external environment.
At first; Root of Kirilow Rhodiola in these article is a kind of precious medicinal plant in the Qinghai-Tibet Platean growth. China's successive dynasties pharmacopeia is all on the books to it; Think that its nourishing, the effect kept fit are " rare in the known tonic ", thus reputation for " east refreshing careless ", " gold plant ", have very high health-care function.The modern medicine study proof has good " fitting originality ", has the ability that improves the organism adaptation severe environment, has the body physiological function of adjusting and makes it to recover normal activity.Be embodied in: 1 resisting oxygen lack, 2 antifatigue effects, 3 dual regulations, the provide protection of 4 pairs of cardiovascular systemss etc.Abroad Root of Kirilow Rhodiola as " adaptation source " appearance medicine, be widely used in antifatigue, anti-ageing and improve aspects such as mental and physical function.Root of Kirilow Rhodiola is aided with the synergy of other former medicines again, reaches strengthening immunity, alleviates the purpose of physical fatigue state.These article " dissolve Chinese medicine that improves the health and wine in " vina in one; Not only prescription is convenient, the property of medicine is stable, safe and effective; And because wine is a kind of good semi-polarity organic solvent; The various effective constituents of Chinese medicine all have been dissolved in wherein, and wine assisting drug, wine help the medicine gesture and gives full play to its effectiveness, improve and render a service.
Secondly, health promoting wine is elite parts of Chinese traditional wine culture in the history of China existing several thousand.Wine is extracting effective components fully, heightens the effect of a treatment.Wine competent medicine tendency, better effects if is main health promoting wine with the Root of Kirilow Rhodiola, wine and women-sensual pursuits is sparkling and crystal-clear, aroma alcohol just, vinosity and suitable has and relaxes the muscles and stimulate the blood circulation, diffusing arteries and veins is dispeled cold, the effect of nourishing and strengthening vital, the contained rhodioside of Root of Kirilow Rhodiola can endocrine regulation, activates pituitary body.Adapt to healthy, sub-health population and drink, thereby reach the adjusting immunity of organisms, alleviate the health-care effect of physical fatigue state.Health promoting wine is convenient to take, is absorbed rapidly, can effectively grasp dosage, is happy to accepted by people.
Another purpose of the present invention provides the preparation method of the Chinese medicine health-care wine of above-mentioned strengthening immunity and alleviating physical fatigue, and this method comprises the following steps:
(1), to take by weighing medicinal material cataclasm, mixing, crude drug is subsequent use;
(2), the agent of preparation lyase is subsequent use;
(3), get 50% of lyase agent total amount and add in the above-mentioned crude drug, soaks after 6~48 hours, with cold-maceration, percolation or circulation dipping extraction method, extracted 3~7 days, the extracting solution filtration gets a juice soup, and is subsequent use;
(4), in addition get 20% of lyase agent total amount, add in the filterable residue of step (3), with cold-maceration, percolation or circulation dipping extraction method, extracted 2~5 days, extracting solution filters, and gets two juice soups, and is subsequent use;
The correctives of 1.0~3.0%V/V of the strong vina total amount of going bail for (5), in addition, and add the thinner that 1/2 of correctives total amount is measured V/V, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), above (3), (4), (5) soup and remaining lyase agent are merged, stir, left standstill 6~48 hours, filter, promptly get.
Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment is following:
(1) Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment (function of enhancing immunity) result:
It is 5 times of liquid concentrators of product that Lei Shi board big gun Paotianhongyangshejiu supplies test agent, red-brown, and the wine degree is 15 degree (product wine wine degree is 40 ± 1 degree), lot number is 070801.Experiment is undertaken by Ministry of Health's " protective foods check and evaluation technique standard " (version in 2003).
Basic, normal, high three dose groups are established in this experiment, are equivalent to 5,10,30 times of the actual intake of people respectively, establish negative control group (zero(ppm) water) and solvent control group (wine base) simultaneously, and continuous 30 days per os give the Lei Shi board big gun Paotianhongyangshejiu of various dose.Experimental result shows: compare with negative control group (zero(ppm) water) and solvent control group (wine base), middle and high dose groups all can increase mouse hemolysis plaque number, and difference all has significance; Middle and high dose groups all can increase phagocytic rate and the phagocytic index that Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell, and difference all has significance.Compare with negative control group (zero(ppm) water), three dose groups all can improve the multiplication capacity of ConA inducing mouse SPL; Low, middle dose groups all can increase the mouse sufficient sole of the foot 24h of portion in a left side and Oh thickness difference observed value and mice serum hemolytic antibody product value, and difference all has significance.
Conclusion: Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) has function of enhancing immunity.
1, experimental data statistics and result: adopt the variance analysis processing data.
1.1 Lei Shi board big gun Paotianhongyangshejiu is to the influence of the multiplication capacity of ConA inducing mouse SPL: the result sees table 1.Raw data meets homoscedasticity and requires (P>0.05), with negative control group (zero(ppm) water) relatively, three dose groups all can improve the multiplication capacity of ConA inducing mouse SPL, difference all has significance (q check, P < 0.05); The multiplication capacity of three dose groups ConA inducing mouse SPLs and solvent control group (wine base) relatively, difference does not have significance (variance analysis, P>0.05).
Table 1, Lei Shi board big gun Paotianhongyangshejiu is to the influence of the multiplication capacity of ConA inducing mouse SPL (X ± SD)
Figure G2008102015364D00041
The q check: compare with negative control group (zero(ppm) water), #P<0.05
1.2 Lei Shi board big gun Paotianhongyangshejiu is to the influence of sheep red blood cell (SRBC) inducing mouse DTH: the result sees table 2.Raw data meets homoscedasticity and requires (P>0.05), with negative control group (zero(ppm) water) relatively, low, middle dose groups all can improve the left back sufficient sole of the foot 24h of portion of mouse and oh thickness difference observed value, difference all has significance (q checks, P < 0.05); Left back sufficient sole of the foot 24h of portion of three dose groups mouse and oh thickness difference observed value and solvent control group (wine base) relatively, difference does not have significance (variance analysis, P>0.05).
Table 2, Lei Shi board big gun Paotianhongyangshejiu is to the influence of sheep red blood cell (SRBC) inducing mouse DTH (X ± SD)
Figure G2008102015364D00051
The q check: compare with negative control group (zero(ppm) water), #P<0.05
1.3 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mice serum hemolysin: the result sees table 3.Raw data meets homoscedasticity and requires (P>0.05), with negative control group (zero(ppm) water) relatively, low, middle dose groups all can improve mice serum hemolytic antibody volume numerical value, difference all has significance (q check, P < 0.05); Three dose groups mice serum hemolytic antibody volume numerical value and solvent control group (wine base) relatively, difference does not have significance (variance analysis, P>0.05).
Table 3, Lei Shi board big gun Paotianhongyangshejiu is to the influence of mice serum hemolysin (X ± SD)
Figure G2008102015364D00052
The q check: compare with negative control group (zero(ppm) water), #P<0.05
1.4 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse antibodies founder cell: the result sees table 4.Raw data meets homoscedasticity and requires (P>0.05), with negative control group (zero(ppm) water) relatively, middle and high dose groups all can increase mouse hemolysis plaque number, difference all has significance (q check, P < 0.05).
Table 4, Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse antibodies founder cell (X ± SD)
Figure G2008102015364D00053
Figure G2008102015364D00061
The q check: compare with negative control group (zero(ppm) water), #P<0.05, with solvent control group (wine base) relatively, ΔP<0.05
1.5 Lei Shi board big gun Paotianhongyangshejiu is engulfed chicken red blood cell to Turnover of Mouse Peritoneal Macrophages influence: the result sees table 5.Phagocytic percentage passes through X=Sin -1P 1/2Carry out data-switching, the data fit homoscedasticity after the conversion requires (P>0.05), the raw data of phagocytic index meets homoscedasticity and requires (P>0.05), the phagocytic rate and the phagocytic index of compare with negative control group (zero(ppm) water), solvent control group (wine base), the equal ability of middle and high dose groups Turnover of Mouse Peritoneal Macrophages being engulfed chicken red blood cell, difference all has significance (q check, P<0.05).
Table 5, Lei Shi board big gun Paotianhongyangshejiu are engulfed the influence (X ± SD) of chicken red blood cell to Turnover of Mouse Peritoneal Macrophages
Figure G2008102015364D00062
The q check: compare with negative control group (zero(ppm) water), #P<0.05, with solvent control group (wine base) relatively, ΔP<0.05
1.6 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse carbon clearance test phagocytic index: the result sees table 6.Raw data meets homoscedasticity and requires (P>0.05), and three dose groups mouse engulf the phagocytic index and negative control group (zero(ppm) water), solvent control group (wine base) comparison of carbon powder, and difference does not have significance (variance analysis, P>0.05).
Table 6, Lei Shi board big gun sky is red to take care of health to the influence of mouse carbon clearance test phagocytic index (X ± SD)
Figure G2008102015364D00063
Figure G2008102015364D00071
1.7 Lei Shi board big gun Paotianhongyangshejiu is to the active influence of NK cells in mice: the result sees table 7.The NK cytoactive is passed through X=Sin -1P 1/2Carry out data-switching, the data fit homoscedasticity after the conversion requires (P>0.05), three dose groups NK cells in mice activity and negative control group (zero(ppm) water), solvent control group (wine base) comparison, difference do not have significance (variance analysis, P>0.05).
Table 7, Lei Shi board big gun Paotianhongyangshejiu is to the influence of NK cytoactive (X ± SD)
Figure G2008102015364D00072
The q check: compare with negative control group (zero(ppm) water), #P<0.05
(2) Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment data (alleviating physical fatigue function) result:
It is 5 times of liquid concentrators of product that Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) supplies test agent, red-brown, and the wine degree is 15 degree (product wine wine degree is 40 ± 1 degree), lot number is 070801.Experiment is undertaken by Ministry of Health's " protective foods check and evaluation technique standard " (version in 2003).
Basic, normal, high three dose groups are established in this experiment, and (8.3,16.7 and 50.0ml/kg) are equivalent to 5,10,30 times of people's recommended amounts respectively, establish negative control group (zero(ppm) water) and solvent control group (wine base) in addition, and per os gives 30 days.Experimental result shows: with negative control group (zero(ppm) water), solvent control group (wine base) relatively, being tried the middle and high dose groups mouse swimming with a load attached to the body time of thing obviously increases, difference all has significance (q check, P < 0.05); Tried in the thing that serum urea content obviously reduces behind the dose groups mouse movement, difference all has significance (q check, P < 0.05); Tried that liver glycogen content all obviously increases behind each dose groups mouse movement of thing, difference all has significance (q check, P < 0.05); Tried that blood lactic acid content and TG-AUC content all obviously reduce behind each dose groups mouse movement of thing, difference all has significance (q check, P < 0.05).With negative control group (zero(ppm) water) relatively, serum urea has obvious minimizing behind low, the high dose group mouse movement, difference all has significance (q check, P < 0.05).
Conclusion: Lei Shi board big gun Paotianhongyangshejiu has effect of relieving physical fatigue.
1, experimental data statistics and result: adopt the variance analysis processing data.
1.1 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse swimming with a load attached to the body time
Table 1. Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse swimming with a load attached to the body time (X ± SD)
Figure G2008102015364D00081
The q check: compare with negative control group, ΔP<0.05 compare #P with solvent control group<0.05
The result sees table 1, and raw data meets homoscedasticity and requires (P>0.05).Tried the middle and high dose groups mouse swimming with a load attached to the body time of thing and compare obvious increase with negative control group (zero(ppm) water), solvent control group (wine base), difference all has significance meaning (q check: P < 0.05).
1.2 the influence of Lei Shi board big gun Paotianhongyangshejiu serum urea during to mouse movement
The influence of table 2. Lei Shi board big gun Paotianhongyangshejiu serum urea during to mouse movement (X ± SD)
Figure G2008102015364D00082
The q check: compare with negative control group, ΔP<0.05 compare #P with solvent control group<0.05
The result sees table 2, and raw data meets homoscedasticity and requires (P>0.05).Tried in the thing behind the dose groups mouse movement serum urea content and compare obvious minimizing with negative control group (zero(ppm) water), solvent control group (wine base), difference all has significance meaning (q check: P < 0.05); Tried that thing is low, serum urea content and the apparent in view minimizing of negative control group (zero(ppm) water) behind the high dose group mouse movement, difference all has significance meaning (q check: P < 0.05).1.3 the influence of Lei Shi board big gun Paotianhongyangshejiu liver starch consumption during to mouse movement
The influence of table 3. Lei Shi board big gun Paotianhongyangshejiu hepatic glycogen content during to mouse movement (X ± SD)
Figure G2008102015364D00092
The q check: compare with negative control group, ΔP<0.05 compare #P with solvent control group<0.05
The result sees table 3, and raw data meets homoscedasticity and requires (P>0.05).Hepatic glycogen content is compared obvious increase with negative control group (zero(ppm) water), solvent control group (wine base) when being tried in the thing dose groups mouse movement, and difference all has significance meaning (q check: P < 0.05).
1.4 Lei Shi board big gun Paotianhongyangshejiu to mouse movement after the influence of blood lactic acid
Table 4. Lei Shi board big gun Paotianhongyangshejiu to mouse movement after the influence (X ± SD) of blood lactic acid
The q check: compare with negative control group, ΔP<0.05 compare #P with solvent control group<0.05
The result sees table 4, and raw data meets homoscedasticity and requires (P>0.05).Tried each dose groups mouse blood lactic acid content of thing before the swimming and compared with negative control group (zero(ppm) water), solvent control group (wine base), difference there are no significant meaning (F check: P>0.05); Swimming back each dose groups of 0min is compared with negative control group (zero(ppm) water), solvent control group (wine base) and all can obviously be reduced blood lactic acid content behind the mouse movement, and difference all has significance meaning q to check: P 0.05); Tried each dose groups of thing and negative control group (zero(ppm) water), solvent control group (wine base) mutually specific energy obviously reduce blood lactic acid TG-AUC content behind the mouse movement, difference all has significance meaning (F check: P < 0.05).
The present invention fills a prescription rationally, has strengthening immunity, the nourishing function of alleviating physical fatigue, and suitable crowd is immunocompromised person, fatiguability person.Easy administration, effect is remarkable, and using value is preferably arranged.
Embodiment
Embodiment 1
Prescription: Root of Heterophylly Faalsestarwort 30g, Root of Kirilow Rhodiola 60g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for (contain alcohol amount 45% ± 2) bent wine 9900ml, and is as bent wine liquid, subsequent use;
(3), get the bent wine 4950ml of raw material and add in the above-mentioned crude drug, soaks after 24 hours, with cold-maceration or percolation or circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is subsequent use;
(4), in addition get raw material song wine 1980ml and add in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
Embodiment 2
Prescription: Root of Heterophylly Faalsestarwort 60g, Root of Kirilow Rhodiola 30g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, cultivated land 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for (contain alcohol amount 45% ± 2) ethanol 9900ml, and is as feed ethanol liquid, subsequent use;
(3), get feed ethanol 4950ml and add in the above-mentioned crude drug, soak after 36 hours, extract with the circulation dipping
Method was extracted 5 days, and extracting solution filters, and got a juice soup, and is subsequent use;
(4), in addition get feed ethanol 1980ml and add in the above-mentioned residue,, extracted 4 days with circulation dipping extraction method,
Extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate,
Subsequent use;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir,
Left standstill 24 hours, and filtered, promptly get.
Embodiment 3
Prescription: Radix Codonopsis 60g, Root of Kirilow Rhodiola 30g, sealwort 40g, wolfberry fruit 50g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 10g, sophora bud 30g, root of Dahurain angelica 30g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is (contain alcohol amount 50% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 36 hours, use the percolation extraction method, extracted 7 days, the extracting solution filtration must a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 36 hours, filter, promptly get.
Embodiment 4
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 30g, turtle shell 40g, cultivated land 50g, Semen Cassiae 30g, lotus seeds 30g, root of kudzu vine 30g, Radix Angelicae Sinensis 40g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for (contain alcohol amount 50% ± 2) ethanol 9900ml, and is as feed ethanol liquid, subsequent use;
(3), feed ethanol 4950ml is added in the above-mentioned crude drug, soak after 48 hours, use the cold soaking extraction method, extracted 5 days, extracting solution filters, a juice soup, subsequent use;
(4), in addition feed ethanol 1980ml is added in the above-mentioned residue, use the cold-maceration extraction method, extracted 4 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
Embodiment 5
Prescription: Root of Heterophylly Faalsestarwort 50g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, cultivated land 60g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is (contain alcohol amount 40% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 48 hours, use the percolation extraction method, extracted 5 days, the extracting solution filtration must a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 36 hours, filter, promptly get.
Embodiment 6
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 50g, sealwort 60g, wolfberry fruit 30g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is (contain alcohol amount 45% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 24 hours, with circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.

Claims (6)

1. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Root of Heterophylly Faalsestarwort 30g, Root of Kirilow Rhodiola 60g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 45% ± 2 bent wine 9900ml, and is as bent wine liquid, subsequent use;
(3), get the bent wine 4950ml of raw material and add in the above-mentioned crude drug, soaks after 24 hours, with cold-maceration or percolation or circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is subsequent use;
(4), in addition get raw material song wine 1980ml and add in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
2. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Root of Heterophylly Faalsestarwort 60g, Root of Kirilow Rhodiola 30g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, cultivated land 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 45% ± 2 ethanol 9900ml, and is as feed ethanol liquid, subsequent use;
(3), get feed ethanol 4950ml and add in the above-mentioned crude drug, soak after 36 hours, with circulation dipping extraction method, extracted 5 days, extracting solution filters, and gets a juice soup, and is subsequent use;
(4), in addition get feed ethanol 1980ml and add in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
3. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Radix Codonopsis 60g, Root of Kirilow Rhodiola 30g, sealwort 40g, wolfberry fruit 50g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 10g, sophora bud 30g, root of Dahurain angelica 30g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 50% ± 2 bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 36 hours, use the percolation extraction method, extracted 7 days, the extracting solution filtration must a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 36 hours, filter, promptly get.
4. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 30g, turtle shell 40g, cultivated land 50g, Semen Cassiae 30g, lotus seeds 30g, root of kudzu vine 30g, Radix Angelicae Sinensis 40g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 50% ± 2 ethanol 9900ml, and is as feed ethanol liquid, subsequent use;
(3), feed ethanol 4950ml is added in the above-mentioned crude drug, soak after 48 hours, use the cold soaking extraction method, extracted 5 days, extracting solution filters, a juice soup, subsequent use;
(4), in addition feed ethanol 1980ml is added in the above-mentioned residue, use the cold-maceration extraction method, extracted 4 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
5. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Root of Heterophylly Faalsestarwort 50g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, cultivated land 60g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 40% ± 2 bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 48 hours, use the percolation extraction method, extracted 5 days, the extracting solution filtration must a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is subsequent use;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 36 hours, filter, promptly get.
6. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that said Chinese medicine health-care wine is:
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 50g, sealwort 60g, wolfberry fruit 30g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug subsequent use;
(2), compound concentration is for containing alcohol amount 45% ± 2 bent wine 9900ml, and is as the bent wine liquid of raw material, subsequent use;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 24 hours, with circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is subsequent use;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is subsequent use;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is subsequent use;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir, left standstill 24 hours, filter, promptly get.
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CN103103057A (en) * 2012-12-18 2013-05-15 徐州鸿宇农业科技有限公司 Preparation method of silkworm caterpillar fungus nutritive liqueur
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CN106390069A (en) * 2016-11-10 2017-02-15 廖亚梅 Chinese herb liquid for motivating self-healing function of human body and preparing and using method thereof
CN107898926A (en) * 2017-12-28 2018-04-13 武汉德智太药科技发展有限公司 One kind keeps fit and healthy health care oral liquid and preparation method thereof

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