CN101724541A - Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue and preparation method thereof - Google Patents

Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue and preparation method thereof Download PDF

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CN101724541A
CN101724541A CN200810201536A CN200810201536A CN101724541A CN 101724541 A CN101724541 A CN 101724541A CN 200810201536 A CN200810201536 A CN 200810201536A CN 200810201536 A CN200810201536 A CN 200810201536A CN 101724541 A CN101724541 A CN 101724541A
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medicinal material
root
chinese medicine
wine
lyase
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CN101724541B (en
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陈保华
徐福莺
薛爱珍
谢松
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SHANGHAI LEIYUN PHARMACEUTICAL INDUSTRY Co Ltd
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SHANGHAI LEIYUN PHARMACEUTICAL INDUSTRY Co Ltd
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Abstract

The invention provides Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue, which is prepared from Chinese traditional medicine raw materials comprising radix pseudostellariae, rhodiola root, sealwort, the fruit of Chinese wolfberry, turtle shell, eucommia bark, cassia seed, lotus nut, kudzu root, bud of Chinese scholartree, radix angelicae, dangshen, Chinese angelica, prepared rhizome of rehmannia and edible auxiliary materials. The mouse functional experiment shows that the Chinese traditional medicine health-care wine has the functions of enhancing the immunity and relieving the physical fatigue. The Chinese traditional medicine health-care wine of the invention has a reasonable formula, is suitable for people with low immunity and easy fatigue, can be taken conveniently and has obvious effect and better application value. The invention also provides a preparation method.

Description

Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue and preparation method thereof
Technical field
The present invention relates to Chinese medicine and health food, be specifically related to Chinese medicine health-care wine (Lei Shi board big gun Paotianhongyangshejiu) of a kind of strengthening immunity and alleviating physical fatigue and preparation method thereof.
Background technology
Increase along with human living standard's raising with to the degree of concern of self health status, the trend that functional health wine rises gradually is irreversible.The future trend of wine industry is transformed to health promoting wine by common wine gradually, pursue natural, advocating healthy consumers demand is that people have the recurrence of blindly moving towards the rational faculty, and as a kind of health promoting wine with the China of accumulateing in the deep history culture, its market potential and potential consumer groups are very considerable.From functional health wine consumption situation, the consumption of health promoting wine accounts for drinks total quantity consumed 2% in the world.Because service competition is more and more fierce, people are also increasing for the pressure of feeling in the work; In addition, the influence of the factors such as change aspect mode of life and food habits causes immunity of organisms and fatigue resistance to descend.Therefore, people wish that can seek to obtain some from Chinese medicine helps Chinese medicine and health food particularly easy to use.Thus, the Chinese medicine health-care wine of exploitation strengthening immunity and alleviating physical fatigue becomes new goal in research.
Summary of the invention
The Chinese medicine health-care wine (Lei Shi board big gun Paotianhongyangshejiu) that the invention provides a kind of strengthening immunity and alleviating physical fatigue is made up of Chinese medicine and edible adjuvant.As Chinese medicine material of the present invention be: Root of Heterophylly Faalsestarwort, Root of Kirilow Rhodiola, sealwort, wolfberry fruit, turtle shell, the bark of eucommia, Semen Cassiae, lotus seeds, the root of kudzu vine, the sophora bud, the root of Dahurain angelica, Radix Codonopsis, Radix Angelicae Sinensis and cultivated land.Edible adjuvant is lyase agent, correctives and thinner.Wherein the lyase agent is bent wine or ethanol (containing alcohol amount 30% ± 2~50% ± 2); Correctives is sucrose, fructose or Xylitol; Thinner is a pure water.
Each components contents proportioning of Chinese medicine of the present invention and edible adjuvant sees the following form:
Medicinal material and auxiliary material Title The content proportioning
Medicinal material Root of Heterophylly Faalsestarwort ??3.0~9.0(g)
Medicinal material Root of Kirilow Rhodiola ??6.0~18.0(g)
Medicinal material Turtle shell ??3.0~9.0(g)
Medicinal material The bark of eucommia ??3.0~9.0(g)
Medicinal material The root of Dahurain angelica ??1.0~3.0(g)
Medicinal material Semen Cassiae ??3.0~9.0(g)
Medicinal material Wolfberry fruit ??4.0~12.0(g)
Medicinal material and auxiliary material Title The content proportioning
Medicinal material Lotus seeds ??2.0~6.0(g)
Medicinal material The root of kudzu vine ??3.0~9.0(g)
Medicinal material The sophora bud ??3.0~9.0(g)
Medicinal material Sealwort ??5.0~15.0(g)
Medicinal material Radix Codonopsis ??3.0~9.0(g)
Medicinal material Cultivated land ??3.0~9.0(g)
Medicinal material Radix Angelicae Sinensis ??3.0~9.0(g)
The lyase agent Bent wine, ethanol (containing alcohol amount 30% ± 2~50% ± 2) ??900~3000(ml)
Correctives Sucrose, fructose or Xylitol 1.0~3.0% (v/v) of medicinal material total amount
Thinner Pure water ??5.0~45.0(g)
This product selects for use Root of Kirilow Rhodiola, the root of kudzu vine, Root of Heterophylly Faalsestarwort, turtle shell, the bark of eucommia, sealwort, the root of Dahurain angelica, Chinese yam, Semen Cassiae, wolfberry fruit, lotus seeds, Radix Codonopsis, cultivated land and Radix Angelicae Sinensis etc. to make for main raw material according to the Chinese medicine theory that takes care of health.Pass through its synergy, can reach strengthening immunity function and alleviating physical fatigue function, improve the adaptive faculty of body to internal and external environment.
At first, Root of Kirilow Rhodiola in this product is a kind of precious medicinal plant in the Qinghai-Tibet Platean growth. China's successive dynasties pharmacopeia is all on the books to it, think that its nourishing, the effect kept fit are " rare in the known tonic ", thus reputation for " east refreshing careless ", " gold plant ", have very high health-care function.The modern medicine study proof has good " suitable originality ", has the ability that improves the organism adaptation severe environment, has the body physiological function of adjusting and makes it to recover normal activity.Be embodied in: 1 resisting oxygen lack, 2 antifatigue effects, 3 dual regulations, the provide protection of 4 pairs of cardiovascular systemss etc.Abroad Root of Kirilow Rhodiola as " adaptation source " sample medicine, be widely used in antifatigue, anti-ageing and improve aspects such as mental and physical function.Root of Kirilow Rhodiola is aided with the synergy of other former medicines again, reaches strengthening immunity, alleviates the purpose of physical fatigue state.This product with the Chinese medicine that improves the health and wine " molten " in the vina of one, not only prescription is convenient, the property of medicine is stable, safe and effective, and because wine is a kind of good semi-polarity organic solvent, the various effective constituents of Chinese medicine all have been dissolved in wherein, wine assisting drug, wine help the medicine gesture and give full play to its effectiveness, improve and render a service.
Secondly, health promoting wine is elite parts of Chinese traditional wine culture in the history of China existing several thousand.Wine is extracting effective components fully, heightens the effect of a treatment.Wine competent medicine tendency, better effects if, based on the health promoting wine of Root of Kirilow Rhodiola, wine and women-sensual pursuits is sparkling and crystal-clear, aroma alcohol just, vinosity and suitable has and relaxes the muscles and stimulate the blood circulation, diffusing arteries and veins is dispeled cold, the effect of nourishing and strengthening vital, the contained rhodioside of Root of Kirilow Rhodiola can endocrine regulation, activates pituitary body.Adapt to healthy, sub-health population and drink, thereby reach the adjusting immunity of organisms, alleviate the health-care effect of physical fatigue state.Health promoting wine is convenient to take, is absorbed rapidly, can effectively grasp dosage, is happy to be accepted by people.
Another purpose of the present invention provides the preparation method of the Chinese medicine health-care wine of above-mentioned strengthening immunity and alleviating physical fatigue, and this method comprises the following steps:
(1), to take by weighing medicinal material cataclasm, mixing, crude drug is standby;
(2), the agent of preparation lyase is standby;
(3), get 50% of lyase agent total amount and add in the above-mentioned crude drug, soaks after 6~48 hours, with cold-maceration, percolation or circulation dipping extraction method, extracted 3~7 days, the extracting solution filtration gets a juice soup, and is standby;
(4), in addition get 20% of lyase agent total amount, in the filterable residue of adding step (3), with cold-maceration, percolation or circulation dipping extraction method, extracted 2~5 days, extracting solution filters, and gets two juice soups, and is standby;
The correctives of 1.0~3.0%V/V of the strong vina total amount of going bail for (5), in addition, and add the thinner that 1/2 of correctives total amount is measured V/V, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), above (3), (4), (5) soup and remaining lyase agent are merged, stir evenly, left standstill 6~48 hours, filter, promptly.
Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment is as follows:
(1) Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment (strengthening immunity function) result:
Lei Shi board big gun Paotianhongyangshejiu is 5 times of concentrated solutions of product for test agent, red-brown, and the wine degree is 15 degree (product wine wine degree is 40 ± 1 degree), lot number is 070801.Experiment is undertaken by Ministry of Health's " protective foods check and evaluation technique standard " (version in 2003).
Basic, normal, high three dosage groups are established in this experiment, be equivalent to 5,10,30 times of the actual intake of people respectively, establish negative control group (distilled water) and solvent control group (wine base) simultaneously, continuous 30 days per os give the Lei Shi board big gun Paotianhongyangshejiu of various dose.Experimental result shows: compare with negative control group (distilled water) and solvent control group (wine base), middle and high dosage group all can increase mouse hemolysis plaque number, and difference all has significance; Middle and high dosage group all can increase phagocytic rate and the phagocytic index that Turnover of Mouse Peritoneal Macrophages is engulfed chicken red blood cell, and difference all has significance.Compare with negative control group (distilled water), three dosage groups all can improve the multiplication capacity of ConA inducing mouse splenic lymphocyte; Low, middle dosage group all can increase the mouse sufficient sole of the foot 24h of portion in a left side and 0h thickness difference observed value and mice serum hemolytic antibody product value, and difference all has significance.
Conclusion: Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) has the strengthening immunity function.
1, experimental data statistics and result: adopt the variance analysis processing data.
1.1 Lei Shi board big gun Paotianhongyangshejiu is to the influence of the multiplication capacity of ConA inducing mouse splenic lymphocyte: the results are shown in Table 1.Raw data meets homoscedasticity and requires (P>0.05), compares with negative control group (distilled water), and three dosage groups all can improve the multiplication capacity of ConA inducing mouse splenic lymphocyte, and difference all has significance (q check, P<0.05); The multiplication capacity of three dosage group ConA inducing mouse splenic lymphocyte and solvent control group (wine base) compare, and difference does not have significance (variance analysis, P>0.05).
Table 1, Lei Shi board big gun Paotianhongyangshejiu is to the influence of the multiplication capacity of ConA inducing mouse splenic lymphocyte (X ± SD)
Figure G2008102015364D0000041
The q check: compare with negative control group (distilled water), #P<0.05
1.2 Lei Shi board big gun Paotianhongyangshejiu is to the influence of sheep red blood cell (SRBC) inducing mouse DTH: the results are shown in Table 2.Raw data meets homoscedasticity and requires (P>0.05), compares with negative control group (distilled water), and low, middle dosage group all can improve left back sufficient sole of the foot 24h of portion of mouse and oh thickness difference observed value, and difference all has significance (q check, P<0.05); Left back sufficient sole of the foot 24h of portion of three dosage group mouse and oh thickness difference observed value and solvent control group (wine base) compare, and difference does not have significance (variance analysis, P>0.05).
Table 2, Lei Shi board big gun Paotianhongyangshejiu is to the influence of sheep red blood cell (SRBC) inducing mouse DTH (X ± SD)
Figure G2008102015364D0000042
Figure G2008102015364D0000051
The q check: compare with negative control group (distilled water), #P<0.05
1.3 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mice serum hemolysin: the results are shown in Table 3.Raw data meets homoscedasticity and requires (P>0.05), compares with negative control group (distilled water), and low, middle dosage group all can improve mice serum hemolytic antibody volume numerical value, and difference all has significance (q check, P<0.05); Three dosage group mice serum hemolytic antibody volume numerical value and solvent control group (wine base) compare, and difference does not have significance (variance analysis, P>0.05).
Table 3, Lei Shi board big gun Paotianhongyangshejiu is to the influence of mice serum hemolysin (X ± SD)
Figure G2008102015364D0000052
The q check: compare with negative control group (distilled water), #P<0.05
1.4 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse antibodies founder cell: the results are shown in Table 4.Raw data meets homoscedasticity and requires (P>0.05), compares with negative control group (distilled water), and middle and high dosage group all can increase mouse hemolysis plaque number, and difference all has significance (q check, P<0.05).
Table 4, Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse antibodies founder cell (X ± SD)
Figure G2008102015364D0000053
Figure G2008102015364D0000061
The q check: compare with negative control group (distilled water), #P<0.05, with solvent control group (wine base) relatively, P<0.05
1.5 Lei Shi board big gun Paotianhongyangshejiu is engulfed chicken red blood cell to Turnover of Mouse Peritoneal Macrophages influence: the results are shown in Table 5.Phagocytic percentage passes through X=Sin -1P 1/2Carry out data-switching, data fit homoscedasticity after the conversion requires (P>0.05), the raw data of phagocytic index meets homoscedasticity and requires (P>0.05), the phagocytic rate and the phagocytic index of compare with negative control group (distilled water), solvent control group (wine base), the equal energy of middle and high dosage group Turnover of Mouse Peritoneal Macrophages being engulfed chicken red blood cell, difference all has significance (q check, P<0.05).
Table 5, Lei Shi board big gun Paotianhongyangshejiu are engulfed the influence (X ± SD) of chicken red blood cell to Turnover of Mouse Peritoneal Macrophages
The q check: compare with negative control group (distilled water), #P<0.05, with solvent control group (wine base) relatively, P<0.05
1.6 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse carbon clearance test phagocytic index: the results are shown in Table 6.Raw data meets homoscedasticity and requires (P>0.05), and phagocytic index and negative control group (distilled water), solvent control group (wine base) that three dosage group mouse engulf carbon powder compare, and difference does not have significance (variance analysis, P>0.05).
Table 6, Lei Shi board big gun sky is red to take care of health to the influence of mouse carbon clearance test phagocytic index (X ± SD)
Figure G2008102015364D0000063
1.7 Lei Shi board big gun Paotianhongyangshejiu is to the active influence of NK cells in mice: the results are shown in Table 7.The NK cytoactive is passed through X=Sin -1P 1/2Carry out data-switching, the data fit homoscedasticity after the conversion requires (P>0.05), and three dosage group NK cells in mice activity and negative control group (distilled water), solvent control group (wine base) comparison, difference do not have significance (variance analysis, P>0.05).
Table 7, Lei Shi board big gun Paotianhongyangshejiu is to the influence of NK cytoactive (X ± SD)
Figure G2008102015364D0000072
The q check: compare with negative control group (distilled water), #P<0.05
(2) Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) functional experiment data (alleviating physical fatigue function) result:
Chinese medicine health-care wine of the present invention (Lei Shi board big gun Paotianhongyangshejiu) is 5 times of concentrated solutions of product for test agent, red-brown, and the wine degree is 15 degree (product wine wine degree is 40 ± 1 degree), lot number is 070801.Experiment is undertaken by Ministry of Health's " protective foods check and evaluation technique standard " (version in 2003).
Basic, normal, high three dosage groups are established in this experiment, and (8.3,16.7 and 50.0ml/kg) are equivalent to 5,10,30 times of people's recommended amounts respectively, establish negative control group (distilled water) and solvent control group (wine base) in addition, and per os gives 30 days.Experimental result shows: with negative control group (distilled water), solvent control group (wine base) relatively, being tried the middle and high dosage group of the thing mouse swimming with a load attached to the body time obviously increases, difference all has significance (q check, P<0.05); Tried in the thing that serum urea content obviously reduces behind the dosage group mouse movement, difference all has significance (q check, P<0.05); Liver glycogen content all obviously increases after being tried each dosage group mouse movement of thing, and difference all has significance (q check, P<0.05); Tried that blood lactic acid content and area under curve content all obviously reduce behind each dosage group mouse movement of thing, difference all has significance (q check, P<0.05).With negative control group (distilled water) relatively, serum urea has obvious minimizing behind low, the high dose group mouse movement, difference all has significance (q check, P<0.05).
Conclusion: Lei Shi board big gun Paotianhongyangshejiu has effect of relieving physical fatigue.
1, experimental data statistics and result: adopt the variance analysis processing data.
1.1 Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse swimming with a load attached to the body time
Table 1. Lei Shi board big gun Paotianhongyangshejiu is to the influence of mouse swimming with a load attached to the body time (X ± SD)
Figure G2008102015364D0000081
The q check: compare with negative control group, #P<0.05 is compared with the solvent control group in P<0.05
The results are shown in Table 1, raw data meets homoscedasticity and requires (P>0.05).Tried the middle and high dosage group of the thing mouse swimming with a load attached to the body time and compare obvious increase with negative control group (distilled water), solvent control group (wine base), difference all has (the q check: P<0.05) of significance meaning.
1.2 the influence of Lei Shi board big gun Paotianhongyangshejiu serum urea during to mouse movement
The influence of table 2. Lei Shi board big gun Paotianhongyangshejiu serum urea during to mouse movement (X ± SD)
Figure G2008102015364D0000082
Figure G2008102015364D0000091
The q check: compare with negative control group, #P<0.05 is compared with the solvent control group in P<0.05
The results are shown in Table 2, raw data meets homoscedasticity and requires (P>0.05).Tried in the thing behind the dosage group mouse movement serum urea content and compare obvious minimizing with negative control group (distilled water), solvent control group (wine base), difference all has (the q check: P<0.05) of significance meaning; Tried that thing is low, serum urea content and the apparent in view minimizing of negative control group (distilled water) behind the high dose group mouse movement, difference all has (the q check: P<0.05) of significance meaning.
1.3 the influence of Lei Shi board big gun Paotianhongyangshejiu liver starch consumption during to mouse movement
The influence of table 3. Lei Shi board big gun Paotianhongyangshejiu hepatic glycogen content during to mouse movement (X ± SD)
The q check: compare with negative control group, #P<0.05 is compared with the solvent control group in P<0.05
The results are shown in Table 3, raw data meets homoscedasticity and requires (P>0.05).Hepatic glycogen content is compared obvious increase with negative control group (distilled water), solvent control group (wine base) when being tried in the thing dosage group mouse movement, and difference all has (the q check: P<0.05) of significance meaning.
1.4 Lei Shi board big gun Paotianhongyangshejiu to mouse movement after the influence of blood lactic acid
Table 4. Lei Shi board big gun Paotianhongyangshejiu to mouse movement after the influence (X ± SD) of blood lactic acid
Figure G2008102015364D0000101
The q check: compare with negative control group, #P<0.05 is compared with the solvent control group in P<0.05
The results are shown in Table 4, raw data meets homoscedasticity and requires (P>0.05).Tried each dosage group mouse blood lactic acid content of thing before the swimming and compared, (the F check: P>0.05) of difference there are no significant meaning with negative control group (distilled water), solvent control group (wine base); Swimming back each dosage group of 0min is compared with negative control group (distilled water), solvent control group (wine base) and all can obviously be reduced blood lactic acid content behind the mouse movement, and difference all has significance meaning q to check: P<0.05); Tried each dosage group of thing and negative control group (distilled water), solvent control group (wine base) mutually specific energy obviously reduce blood lactic acid area under curve content behind the mouse movement, difference all has (the F check: P<0.05) of significance meaning.
The present invention fills a prescription rationally, has strengthening immunity, the nourishing function of alleviating physical fatigue, and suitable crowd is immunocompromised person, fatiguability person.Easy administration, effect is remarkable, and using value is preferably arranged.
Embodiment
Embodiment 1
Prescription: Root of Heterophylly Faalsestarwort 30g, Root of Kirilow Rhodiola 60g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is for (contain alcohol amount 45% ± 2) bent wine 9900ml, and is as bent wine liquid, standby;
(3), get the bent wine 4950ml of raw material and add in the above-mentioned crude drug, soaks after 24 hours, with cold-maceration or percolation or circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is standby;
(4), in addition get raw material song wine 1980ml and add in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is standby;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir evenly, left standstill 24 hours, filter, promptly.
Embodiment 2
Prescription: Root of Heterophylly Faalsestarwort 60g, Root of Kirilow Rhodiola 30g, sealwort 50g, wolfberry fruit 40g, turtle shell 30g, cultivated land 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is for (contain alcohol amount 45% ± 2) ethanol 9900ml, and is as feed ethanol liquid, standby;
(3), get feed ethanol 4950ml and add in the above-mentioned crude drug, soak after 36 hours, with circulation dipping extraction method, extracted 5 days, extracting solution filters, and gets a juice soup, and is standby;
(4), in addition get feed ethanol 1980ml and add in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is standby;
(5), in addition take by weighing sucrose 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir evenly, left standstill 24 hours, filter, promptly.
Embodiment 3
Prescription: Radix Codonopsis 60g, Root of Kirilow Rhodiola 30g, sealwort 40g, wolfberry fruit 50g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 20g, root of kudzu vine 10g, sophora bud 30g, root of Dahurain angelica 30g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is (contain alcohol amount 50% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, standby;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 36 hours, use the percolation extraction method, extracted 7 days, the extracting solution filtration must a juice soup, and is standby;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is standby;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir evenly, left standstill 36 hours, filter, promptly.
Embodiment 4
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 30g, turtle shell 40g, cultivated land 50g, Semen Cassiae 30g, lotus seeds 30g, root of kudzu vine 30g, Radix Angelicae Sinensis 40g, root of Dahurain angelica 10g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is for (contain alcohol amount 50% ± 2) ethanol 9900ml, and is as feed ethanol liquid, standby;
(3), feed ethanol 4950ml is added in the above-mentioned crude drug, soak after 48 hours, use the cold soaking extraction method, extracted 5 days, extracting solution filters, a juice soup, standby;
(4), in addition feed ethanol 1980ml is added in the above-mentioned residue, use the cold-maceration extraction method, extracted 4 days, the extracting solution filtration must two juice soups, and is standby;
(5), in addition take by weighing Xylitol 200g, add pure water 100g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and remaining feed ethanol liquid 2970ml, merge, stir evenly, left standstill 24 hours, filter, promptly.
Embodiment 5
Prescription: Root of Heterophylly Faalsestarwort 50g, Root of Kirilow Rhodiola 30g, sealwort 30g, wolfberry fruit 40g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, cultivated land 60g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is (contain alcohol amount 40% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, standby;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 48 hours, use the percolation extraction method, extracted 5 days, the extracting solution filtration must a juice soup, and is standby;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, use the percolation extraction method, extracted 3 days, the extracting solution filtration must two juice soups, and is standby;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir evenly, left standstill 36 hours, filter, promptly.
Embodiment 6
Prescription: Root of Heterophylly Faalsestarwort 40g, Root of Kirilow Rhodiola 50g, sealwort 60g, wolfberry fruit 30g, turtle shell 30g, bark of eucommia 30g, Semen Cassiae 30g, lotus seeds 10g, root of kudzu vine 30g, sophora bud 30g, root of Dahurain angelica 20g
Method:
(1), take by weighing medicinal material 360g, cataclasm, mixing, crude drug standby;
(2), compound concentration is (contain alcohol amount 45% ± 2) bent wine 9900ml, and is as the bent wine liquid of raw material, standby;
(3), the bent wine 4950ml of raw material is added in the above-mentioned crude drug, soaks after 24 hours, with circulation dipping extraction method, extracted 6 days, the extracting solution filtration gets a juice soup, and is standby;
(4), in addition the bent wine 1980ml of raw material is added in the above-mentioned residue, with circulation dipping extraction method, extracted 4 days, extracting solution filters, and gets two juice soups, and is standby;
(5), in addition take by weighing fructose 346g, add pure water 173g again, heating for dissolving is crossed 100 mesh sieves, gets lysate, and is standby;
(6), with above (3), (4), (5) soup and the bent wine liquid of remaining raw material 2970ml, merge, stir evenly, left standstill 24 hours, filter, promptly.

Claims (5)

1. the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue is characterized in that described Chinese medicine health-care wine is made up of Chinese medicine material and edible adjuvant; Described Chinese medicine material is: Root of Heterophylly Faalsestarwort, Root of Kirilow Rhodiola, sealwort, wolfberry fruit, turtle shell, the bark of eucommia, Semen Cassiae, lotus seeds, the root of kudzu vine, the sophora bud, the root of Dahurain angelica, Radix Codonopsis, Radix Angelicae Sinensis and cultivated land; Edible adjuvant is lyase agent, correctives and thinner; Each components contents proportioning is:
Medicinal material and auxiliary material title content proportioning
Medicinal material Root of Heterophylly Faalsestarwort 3.0~9.0g
Medicinal material Root of Kirilow Rhodiola 6.0~18.0g
Medicinal material turtle shell 3.0~9.0g
The medicinal material bark of eucommia 3.0~9.0g
The medicinal material root of Dahurain angelica 1.0~3.0g
Medicinal material Semen Cassiae 3.0~9.0g
Medicinal material wolfberry fruit 4.0~12.0g
Medicinal material lotus seeds 2.0~6.0g
The medicinal material root of kudzu vine 3.0~9.0g
The medicinal material sophora bud 3.0~9.0g
Medicinal material sealwort 5.0~15.0g
Medicinal material Radix Codonopsis 3.0~9.0g
Medicinal material cultivated land 3.0~9.0g
Medicinal material Radix Angelicae Sinensis 3.0~9.0g
Lyase agent 900~3000ml
1.0%~3.0%V/V of correctives medicinal material total amount
Thinner pure water 5.0~45.0g.
2. according to the Chinese medicine health-care wine of described a kind of strengthening immunity of claim 1 and alleviating physical fatigue, it is characterized in that described lyase agent is that bent wine or ethanol contain alcohol amount 30% ± 2~50% ± 2; Correctives is sucrose, fructose or Xylitol.
3. the preparation method of the Chinese medicine health-care wine of strengthening immunity and alleviating physical fatigue according to claim 1 is characterized in that this method comprises the following steps:
(1), to take by weighing medicinal material cataclasm, mixing, crude drug is standby;
(2), the agent of preparation lyase is standby;
(3), get 50% of lyase agent total amount and add in the above-mentioned crude drug, soaks after 6~48 hours, with cold-maceration, percolation or circulation dipping extraction method, extracted 3~7 days, the extracting solution filtration gets a juice soup, and is standby;
(4), get 20% of lyase agent total amount, add in the filterable residue of step (3), with cold-maceration, percolation or circulation dipping extraction method, extracted 2~5 days, extracting solution filters, and gets two juice soups, and is standby;
(5), the correctives of 1.0~3.0%V/V of the strong vina total amount of going bail for, and add the thinner of 1/2 amount V/V of correctives total amount, heating for dissolving is crossed 100 mesh sieves, lysate, standby;
(6), above (3), (4), (5) soup and remaining lyase agent are merged, stir evenly, left standstill 6~48 hours, filter, promptly.
4. the Chinese medicine composition application in the Chinese medicine and health food of preparation strengthening immunity and alleviating physical fatigue is characterized in that this Chinese medicine composition is made up of following component, and each components contents proportioning is:
Medicinal material and auxiliary material title content proportioning
Medicinal material Root of Heterophylly Faalsestarwort 3.0~9.0g
Medicinal material Root of Kirilow Rhodiola 6.0~18.0g
Medicinal material turtle shell 3.0~9.0g
The medicinal material bark of eucommia 3.0~9.0g
The medicinal material root of Dahurain angelica 1.0~3.0g
Medicinal material Semen Cassiae 3.0~9.0g
Medicinal material wolfberry fruit 4.0~12.0g
Medicinal material lotus seeds 2.0~6.0g
The medicinal material root of kudzu vine 3.0~9.0g
The medicinal material sophora bud 3.0~9.0g
Medicinal material sealwort 5.0~15.0g
Medicinal material Radix Codonopsis 3.0~9.0g
Medicinal material cultivated land 3.0~9.0g
Medicinal material Radix Angelicae Sinensis 3.0~9.0g
Lyase agent 900~3000ml
1.0%~3.0%V/V of correctives medicinal material total amount
Thinner pure water 5.0~45.0g
Described lyase agent is that bent wine or ethanol contain alcohol amount 30% ± 2~50% ± 2; Correctives is sucrose, fructose or Xylitol.
5. according to the application of claim 4, it is characterized in that described Chinese medicine and health food is a Chinese medicine health-care wine.
CN2008102015364A 2008-10-22 2008-10-22 Chinese traditional medicine health-care wine for enhancing immunity and relieving physical fatigue and preparation method thereof Expired - Fee Related CN101724541B (en)

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CN102258708A (en) * 2011-07-12 2011-11-30 深圳市慧慈现代生物科技有限公司 Health-preserving wine and preparation method thereof
CN103103057A (en) * 2012-12-18 2013-05-15 徐州鸿宇农业科技有限公司 Preparation method of silkworm caterpillar fungus nutritive liqueur
CN103131611A (en) * 2013-02-28 2013-06-05 徐州古彭酒业有限公司 Alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis
CN103431320A (en) * 2013-07-25 2013-12-11 柳培健 Preparation method of health canned asparagus lettuce in brine
CN105695255A (en) * 2014-11-27 2016-06-22 衡阳市旺人食品实业有限公司 Rhodiola root cassia seed health wine and preparation method thereof
CN106390069A (en) * 2016-11-10 2017-02-15 廖亚梅 Chinese herb liquid for motivating self-healing function of human body and preparing and using method thereof
CN107898926A (en) * 2017-12-28 2018-04-13 武汉德智太药科技发展有限公司 One kind keeps fit and healthy health care oral liquid and preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102258708A (en) * 2011-07-12 2011-11-30 深圳市慧慈现代生物科技有限公司 Health-preserving wine and preparation method thereof
CN102258708B (en) * 2011-07-12 2012-11-21 深圳市慧慈现代生物科技有限公司 Health-preserving wine and preparation method thereof
CN103103057A (en) * 2012-12-18 2013-05-15 徐州鸿宇农业科技有限公司 Preparation method of silkworm caterpillar fungus nutritive liqueur
CN103131611A (en) * 2013-02-28 2013-06-05 徐州古彭酒业有限公司 Alcoholic beverage for preventing cervical spondylosis, lumbar disc herniation and scapulohumeral periarthritis
CN103431320A (en) * 2013-07-25 2013-12-11 柳培健 Preparation method of health canned asparagus lettuce in brine
CN105695255A (en) * 2014-11-27 2016-06-22 衡阳市旺人食品实业有限公司 Rhodiola root cassia seed health wine and preparation method thereof
CN106390069A (en) * 2016-11-10 2017-02-15 廖亚梅 Chinese herb liquid for motivating self-healing function of human body and preparing and using method thereof
CN107898926A (en) * 2017-12-28 2018-04-13 武汉德智太药科技发展有限公司 One kind keeps fit and healthy health care oral liquid and preparation method thereof

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