CN101721527B - Traditional Chinese medicine jewelry cream and preparation method thereof - Google Patents
Traditional Chinese medicine jewelry cream and preparation method thereof Download PDFInfo
- Publication number
- CN101721527B CN101721527B CN2009101774066A CN200910177406A CN101721527B CN 101721527 B CN101721527 B CN 101721527B CN 2009101774066 A CN2009101774066 A CN 2009101774066A CN 200910177406 A CN200910177406 A CN 200910177406A CN 101721527 B CN101721527 B CN 101721527B
- Authority
- CN
- China
- Prior art keywords
- jewelry
- radix
- cream
- grams
- gram
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The present invention discloses traditional Chinese medicine jewelry cream which comprises (the preparation of 1000 grams of jewelry cream is taken as a reference, and the unit is gram) the following components: 50 of mother-of-pearl, 2 of bezoar, 20 of redroot gromwell root, 55 of giant knotweed, 45 of yellow-corktree bark, 40 of rhubarb and 30 of licorice. The preparation method of the traditional Chinese medicine jewelry cream comprises the following steps: (1) pulverizing the rhubarb, the redroot gromwell root and the giant knotweed into coarse particles, percolating by 75% of ethanol, filtering and concentrating to 500 milliliters; (2) pulverizing the bezoar and sieving by a sieve of NO.7 for later use; (3) after soaking the mother-of-pearl, the yellow-corktree bark and the licorice into 500milliliters of sea buckthorn oil for one week, heating to a condition that the traditional Chinese medicines are in a dry yellow color, deslagging, filtering, adding the bezoar powder obtained in the step (2) after the temperature is lowered to 50 DEG C and mixing evenly; (4) adding 50 grams of honey into the liquor obtained in the step (1), heating to 80 DEG C and adding 1 gram of ethylparaben for later use; and (5) heating the mixture obtained in the step (3) to 70 DEG C, adding 100 grams of glyceride monostearate and 60 grams of beeswax and stirring evenly; adding into the step (4) and emulsifying by a homogenizer quickly so as to obtain the product. The product is suitable for preventing and treating radiodermatitis and ulcer.
Description
Technical field: the present invention relates to a kind of Chinese medicine jewelry cream, belong to medical preparing technical field.
Technical background
Radiodermatitis, ulcer occurrence rate in treatment of cancer is very high, and does not have good medicine.Therefore prevent that radiodermatitis, radiation injury from being the task of top priority.About clinically 70% tumor patient is accepted radiotherapy.Lonizing radiation to tumor cytotoxicity the time normal structure also produce biological effect, clinical manifestation is that skin mucosa erythema occurs, does, moist reaction, ulcer etc.Radiation skin injury is different from general inflammation, burn and ulcer, and lonizing radiation directly act on skin and deep tissue cell thereof, and gradual regression and necrosis take place, and the delay time is long, finally form extensive fibrosis.Cause the infringement of blood capillary and little vascular endothelial cell simultaneously, produce endovasculitis, cause intimal thickening, ischemia such as luminal stenosis, obturation or thrombosis sexually revise, so necrosis is carrying out property, in case ulcer is difficult to the new life of formation of unsoundness granulation tissue and vasoganglion, thereby the probability of spontaneous recovery is very little.Radiation skin injury has a strong impact on patient's quality of life, brings great misery to patient.Existing Therapeutic Method has outer be coated with gentamycin, triethanolamine, povidone iodine, zicao soft plaster etc., poor effect.At reality, develop a kind of Chinese medicine jewelry cream.
Summary of the invention
The objective of the invention is to deficiency, a kind of Chinese medicine jewelry cream and preparation method thereof is provided at the prior art existence.
The present invention is a kind of Chinese medicine skin, mucosa external-application cream.In the prescription with the Concha Margaritifera YANG hyperactivity suppressing of calming the nerves, the convergence granulation promoting; Calculus Bovis (another name: ugly treasured), heat-clearing and toxic substances removing, the detumescence of dispeling the wind.The blood stasis dispelling of Borneolum Syntheticum eliminating stagnation, reducing swelling and alleviating pain, the function of evacuation of pus granulation promoting is a principal agent with Concha Margaritifera, Calculus Bovis, and with the Radix Et Rhizoma Rhei clearing away heat-damp and promoting diuresis,, killing parasites for relieving itching; Be aided with the Rhizoma Polygoni Cuspidati promoting blood circulation to restore menstrual flow, removing obstruction in the collateral to relieve pain; The Cortex Phellodendri heat-clearing and toxic substances removing, dampness removing to stop itchin; Radix Arnebiae (Radix Lithospermi) detoxifcation rash, promoting blood circulation and cooling blood; Radix Glycyrrhizae and middle detoxifcation, the medicines such as hundred medicines that are in harmonious proportion are made the Chinese medicine jewelry cream.Has tangible heat-clearing and toxic substances removing, the effect of reducing swelling and alleviating pain, putrefaction-removing granulation-promoting.Be applicable to and prevent and treat radiodermatitis, radiation ulcer etc. have unique curative effect.Also can be used for treating skin, mucosal inflammation, ulcer and burn etc.
The concrete proportioning of forming comprises that following active ingredient (is as the criterion unit to prepare 1000 gram jewelry creams: (gram): Concha Margaritifera 20-200 Calculus Bovis 2-50 Radix Arnebiae (Radix Lithospermi) 10-100 Rhizoma Polygoni Cuspidati 10-150 Cortex Phellodendri 20-120 Radix Et Rhizoma Rhei 10-110 Radix Glycyrrhizae 10-100 Fructus Hippophae 20-300 Borneolum Syntheticum 2-30;
Prove through repetition test, in product of the present invention, when the consumption of Concha Margaritifera is lower than 10 grams, will make the jewelry cream removing toxic substances and promoting granulation, the YANG hyperactivity suppressing of calming the nerves, the function of tonic chord of convergence granulation promoting descends, and influences the curative effect of product putrefaction-removing granulation-promoting of the present invention, the YANG hyperactivity suppressing of calming the nerves; When being higher than 100 grams, do not influence the function and the curative effect of product of the present invention, do not have side effects yet, facts have proved with its consumption to be preferably between the 20-200 gram.When the consumption of Calculus Bovis, Borneolum Syntheticum is lower than 2 grams, will the effect of product heat-clearing and toxic substances removing of the present invention, anti-inflammatory analgetic be descended.The purpose that adds Calculus Bovis is for pathogenic fire purging poison, clearing away heart-fire, and the row knot stagnates, the detumescence pain.Therefore, the consumption of Calculus Bovis should be between 2-50.Borneolum Syntheticum has sensible, and therefore kind function of scurrying adds the Borneolum Syntheticum assistant and make other each herbal medicine in the invention product ratio of components bring into play its effect better, and the optimum amount of Borneolum Syntheticum is the 2-30 gram; When the consumption of Radix Et Rhizoma Rhei is lower than 10 grams, will make the function reduction of heat clearing away, pathogenic fire purging, influence its curative effect; When consumption was higher than 200 grams, side effect will appear.Therefore, the consumption of Radix Et Rhizoma Rhei is preferably between the 10-110 gram.The optimum amount of Rhizoma Polygoni Cuspidati and Cortex Phellodendri is respectively 10-150 gram and 20-120 gram; Therefore the best proportioning of forming of the present invention is as the criterion unit to prepare 1000 gram jewelry creams: (gram) Concha Margaritifera 50 Calculus Boviss 2 Radix Arnebiae (Radix Lithospermi)s 20 Rhizoma Polygoni Cuspidati 55 Cortex Phellodendris 45 Radix Et Rhizoma Rhei 40 Radix Glycyrrhizaes 30
The preparation method of jewelry cream of the present invention is characterized in that may further comprise the steps:
(1) Radix Et Rhizoma Rhei of aequum, Radix Arnebiae (Radix Lithospermi), Rhizoma Polygoni Cuspidati cleaned, after the drying, be ground into coarse granule, use 75% ethanol percolation, extract the active ingredient in the crude drug, reclaim ethanol, add distilled water and precipitate, filter 500 milliliters of purification medicinal liquids;
(2) Calculus Bovis of aequum is pulverized, crossed sieve No. seven, standby;
(3) Concha Margaritifera of aequum, Cortex Phellodendri, Radix Glycyrrhizae are invaded leave standstill a week in 500 milliliters of Oleum Hippophaes after, slow fire is heated to Chinese medicine when being withered yellow, stops heating, remove slag, filter, filtrate is concentrated into 250 milliliters, treat that temperature reduces to 50 ℃, add step (2) gained medicated powder mix homogeneously;
(4) (1) medicinal liquid is added Mel 50 grams, be heated to 80 ℃, add Ethyl Hydroxybenzoate 1 and restrain stand-by;
(5) (3) are heated to 70 ℃ and add single-stearic acid glyceride 100 grams, Cera Flava 60 grams stir well.Add rapidly and use all machine emulsifying of breast in (4), promptly get product of the present invention.
The present invention compared with prior art has the following advantages:
1. clinical with jewelry cream radiotherapy dermatitis, ulcer effective percentage 98%; There is significant differences matched group zicao soft plaster effective percentage 66.6 statistical procedures P＜0.01;
2. treating both the principal and secondary aspects of a disease, Calculus Bovis of the present invention, the pain relieving of Rhizoma Polygoni Cuspidati clearing heat for detumescence are characteristics, show quick-actingly, adopt Radix Et Rhizoma Rhei eliminating fire and detoxication, activating blood circulation and dissipating blood stasis, and are equipped with Cortex Phellodendri heat-clearing and toxic substances removing, dampness removing to stop itchin.The Concha Margaritifera removing the necrotic tissue and promoting granulation, the YANG hyperactivity suppressing of calming the nerves, all medicines complement each other, and treating both the principal and secondary aspects of a disease is struck home;
3. discard the dross and select the essential, propose, get its active ingredient with wine dipper, oil respectively, more can bring into play drug effect according to different Chinese herbal medicine;
4. local application makes diseased region drug level height, has avoided the liver first-pass effect again;
5. nontoxic, the side effect of product of the present invention, application safety is reliable.
Following embodiment is in order to illustrate the present invention:
Below provided three groups of different proportionings (to prepare 1000 grams is benchmark, unit: restrain) of forming of product jewelry cream of the present invention:
First group: Concha Margaritifera 100 Calculus Boviss 20 Rhizoma Polygoni Cuspidati 100 Cortex Phellodendris 120 Radix Et Rhizoma Rhei 110 Fructus Hippophaes 100 Radix Glycyrrhizaes 100 Borneolum Syntheticums 30
Second group: Concha Margaritifera 10 Calculus Boviss 5 Rhizoma Polygoni Cuspidati 20 Cortex Phellodendris 20 Radix Et Rhizoma Rhei 20 Radix Arnebiae (Radix Lithospermi)s 20 Borneolum Syntheticums 10
The 3rd group: Concha Margaritifera 50 Calculus Boviss 2 Radix Arnebiae (Radix Lithospermi)s 20 Rhizoma Polygoni Cuspidati 55 Cortex Phellodendris 45 Radix Et Rhizoma Rhei 40 Radix Glycyrrhizaes 30
To be respectively applied for the toxicity test that rabbit, Cavia porcellus carry out toxicity test and agents area than obtained medicine by above-mentioned three assembly, the result shows that product of the present invention has no side effect; Above-mentioned three assembly are carried out the drug effect zoology test than obtained medicine, and the result shows that product of the present invention is to staphylococcus aureus, and Staphylococcus albus and Klebsiella pneumoniae all have antibacterial action, and be stronger to the antibacterial action of fungus.Can reduce inflammatory sign occurrence rate to the guinea pig skin traumatic ulcer, and have the effect of accelerating wound healing, three groups all have tangible antiinflammatory action to different inflammatory animal models.
Be respectively applied for than the medicine of gained with above-mentioned three assembly animal is carried out the antiulcer test, the result shows that than obtained effect of drugs the best, side effect is minimum with the 3rd assembly.This and clinical treatment patient outcomes match.For this reason, the best of jewelry cream of the present invention composition should be (to be equipped with 1000 gram jewelry creams is benchmark, unit: restrain)
Concha Margaritifera 50 Calculus Boviss 2 Radix Arnebiae (Radix Lithospermi)s 20 Rhizoma Polygoni Cuspidati 55 Cortex Phellodendris 45 Radix Et Rhizoma Rhei 40 Radix Glycyrrhizaes 30
The concrete preparation method of the said goods comprises following technical process: clean the Radix Et Rhizoma Rhei of aequum, Radix Arnebiae (Radix Lithospermi), Rhizoma Polygoni Cuspidati, after the drying, be ground into coarse granule (1), use 75% ethanol percolation, extract the active ingredient in the crude drug, reclaim ethanol, add the distilled water precipitation, filter 500 milliliters of purification medicinal liquids;
(2) Calculus Bovis of aequum is pulverized, crossed sieve No. seven, standby;
(3) Concha Margaritifera of aequum, Cortex Phellodendri, Radix Glycyrrhizae are invaded leave standstill a week in 500 milliliters of Oleum Hippophaes after, slow fire is heated to Chinese medicine when being withered yellow, stops heating, remove slag, filter, filtrate is concentrated into 250 milliliters, treat that temperature reduces to 50 ℃, add step (2) gained medicated powder mix homogeneously;
(4) (1) medicinal liquid is added Mel 50 grams, be heated to 80 ℃, add Ethyl Hydroxybenzoate 1 and restrain stand-by;
(5) (3) are heated to 70 ℃ and add single-stearic acid glyceride 100 grams, Cera Flava 60 grams stir well.Add and use all machine emulsifying of breast in (4) rapidly, promptly get product of the present invention.
Product of the present invention is pink cream, shows through stability test, and product room temperature of the present invention was placed 18 months down, and testing result meets quality standard.
Product efficacy of the present invention: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, putrefaction-removing granulation-promoting.Be applicable to and prevent and treat radiodermatitis, ulcer.Also can be used for skin, mucosal inflammation, ulcer and burn.3-5 minute pain disappears after patient's medication, and all left and right sides ulcer healing is evident in efficacy.
The using method of product of the present invention: jewelry cream external every day 2-4 time, each an amount of.
Claims (2)
1. Chinese medicine jewelry cream is characterized in that making raw materials of effective components and consists of: be as the criterion to prepare 1000 gram jewelry creams, unit is gram
Concha Margaritifera 20-200 Calculus Bovis 2-50 Radix Arnebiae (Radix Lithospermi) 10-100 Rhizoma Polygoni Cuspidati 10-150 Cortex Phellodendri 20-120 Radix Et Rhizoma Rhei 10-110 Radix Glycyrrhizae 10-100 Fructus Hippophae 20-300 Borneolum Syntheticum 2-30.
2. Chinese medicine jewelry cream, it is characterized in that making the raw materials of effective components best group becomes: be as the criterion to prepare 1000 gram jewelry creams, unit is gram
Concha Margaritifera 50 Calculus Boviss 2 Radix Arnebiae (Radix Lithospermi)s 20 Rhizoma Polygoni Cuspidati 55 Cortex Phellodendris 45 Radix Et Rhizoma Rhei 40 Radix Glycyrrhizaes 30.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101774066A CN101721527B (en) | 2009-09-29 | 2009-09-29 | Traditional Chinese medicine jewelry cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101774066A CN101721527B (en) | 2009-09-29 | 2009-09-29 | Traditional Chinese medicine jewelry cream and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101721527A CN101721527A (en) | 2010-06-09 |
| CN101721527B true CN101721527B (en) | 2011-11-16 |
Family
ID=42443477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101774066A Active CN101721527B (en) | 2009-09-29 | 2009-09-29 | Traditional Chinese medicine jewelry cream and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101721527B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893395A (en) * | 2014-04-15 | 2014-07-02 | 黎清华 | Preparation method of plaster for treating burns |
| CN103989807B (en) * | 2014-05-30 | 2016-05-25 | 薛洁 | A kind of external-applied ointment for the treatment of bedsore |
| CN104173543B (en) * | 2014-09-10 | 2016-07-06 | 江苏省中医药研究院 | A kind of Chinese medicine composition treating incontinence dermatitis |
| CN106581245A (en) * | 2016-01-25 | 2017-04-26 | 袁绍明 | Traditional Chinese medicine composition ointment for treating deep burn |
| CN108635479A (en) * | 2018-06-24 | 2018-10-12 | 覃海平 | A kind of Chinese medicine preparation and preparation method thereof for treating burn, scald |
| CN110859883A (en) * | 2019-12-18 | 2020-03-06 | 河南中医药大学 | External-use tiger ginseng leaf essential oil for treating skin ulcer |
| CN114159511B (en) * | 2021-12-31 | 2022-12-27 | 广西中医药大学附属瑞康医院 | Traditional Chinese medicine preparation for preventing and treating radioactive skin injury and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1411825A (en) * | 2001-10-16 | 2003-04-23 | 章国华 | Medicine for curing burn and scald and its production method |
-
2009
- 2009-09-29 CN CN2009101774066A patent/CN101721527B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1411825A (en) * | 2001-10-16 | 2003-04-23 | 章国华 | Medicine for curing burn and scald and its production method |
Non-Patent Citations (3)
| Title |
|---|
| 刘巧.中医皮肤病的治疗.《中国中西医结合皮肤性病学杂志》.2009,第8卷(第2期),122-124. * |
| 姜林嵩 等.试论中药抗感染的优势.《甘肃科技纵横》.2008,第37卷(第2期),175. * |
| 张洪恩.清热解毒药的应用与进展.《辽宁中医杂志》.1981,(第12期),45-48. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101721527A (en) | 2010-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101721527B (en) | Traditional Chinese medicine jewelry cream and preparation method thereof | |
| CN102205026B (en) | Chinese medicinal composition for treating children chronic sinusitis and preparation method thereof | |
| CN103202880B (en) | Medicine for treating allergic rhinitis and method for preparing medicine | |
| CN103272149B (en) | Medicine composition for preventing and treating postoperative complication of anorectal diseases | |
| CN104083498A (en) | Rhinitis ointment | |
| CN103784659A (en) | Traditional Chinese medicine tincture for treating corns on feet | |
| CN101366845A (en) | Ointment for treating ache of neck, shoulder, waist and leg | |
| CN102813900B (en) | External medicine for treating foot corns | |
| CN104189125B (en) | Externally used Yao medicine composition for treating gout and preparation method thereof | |
| CN105456644A (en) | External lotion for perineal laceration postoperative nursing and preparation method thereof | |
| CN103585334B (en) | Compound diaper ointment | |
| CN104623304A (en) | Lotion for treating chronic skin ulcer caused by damp-heat and toxicity accumulation and preparation method of lotion | |
| KR101058072B1 (en) | Vegetable burn remedies | |
| CN104189489A (en) | Medicament with effect of treating chronic eczema and preparation method thereof | |
| CN103656107A (en) | Medicine for treating tinea favosa and preparation method thereof | |
| CN109908312B (en) | Hemorrhoid ointment and preparation method thereof | |
| CN107753722A (en) | A kind of Chinese herbal medicine paste for treating hemorrhoid and preparation method thereof | |
| CN100478007C (en) | Plaster for treating traumatic injuries and rheumatism, and its prepn. method | |
| CN103751554A (en) | Medicament for treating skin allergy | |
| CN105106590A (en) | Medicine for treating allergic rhinitis | |
| CN106581269A (en) | Skin allergy treating traditional Chinese medicine composition | |
| CN103316098B (en) | Rhinitis and nasal polyp liquid medicine and production method thereof | |
| CN104398796A (en) | Wetly-applied agent for exudative skin diseases and preparation method thereof | |
| CN110538317A (en) | blood vessel plaque dissolving and eliminating pill and preparation method thereof | |
| CN117618508A (en) | Antibacterial ointment for treating rhinitis and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Free format text: FORMER OWNER: WANG XIAOQING WEN YAN Effective date: 20120605 Owner name: BEIJING HGPT TECHNOLOGY + TRADE CO., LTD. Free format text: FORMER OWNER: WEN ZHITING Effective date: 20120605 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 100089 HAIDIAN, BEIJING TO: 100073 FENGTAI, BEIJING |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20120605 Address after: Beijing city 100073 West Fourth Ring Road No. 46 Guorun commercial building block A room 2505 Patentee after: Beijing HGPT Technology & Trade Co., Ltd. Address before: 100089, No. 2, building 19, West Hospital, Beijing Foreign Studies University, 19 West Third Ring Road, Beijing, 602 Co-patentee before: Wang Xiaoqing Patentee before: Wen Zhiting Co-patentee before: Wen Yan |