CN104173543B - A kind of Chinese medicine composition treating incontinence dermatitis - Google Patents

A kind of Chinese medicine composition treating incontinence dermatitis Download PDF

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CN104173543B
CN104173543B CN201410458609.3A CN201410458609A CN104173543B CN 104173543 B CN104173543 B CN 104173543B CN 201410458609 A CN201410458609 A CN 201410458609A CN 104173543 B CN104173543 B CN 104173543B
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chinese medicine
medicine composition
powder
incontinence dermatitis
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CN104173543A (en
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刘晓蓉
刘小莉
葛云霞
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Jiangsu Provincial Insititute of Traditional Chinese Medicine
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Jiangsu Provincial Insititute of Traditional Chinese Medicine
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Abstract

The invention belongs to the Chinese Traditional Medicine application in Modern Nursing field, particularly in the application in treatment patient bedridden in long term complication incontinence dermatitis.Incontinence dermatitis clinical manifestation is: erythema, edema, impregnate, strip off, damaged, pimple and vesicle are formed.Present invention solves the technical problem that as, while there is better healing effect, solving the side effect that western medicine incontinence dermatitis is brought.The technical scheme is that a kind of Chinese medicine composition treating incontinence dermatitis of employing, said composition is made up of the crude drug of following weight ratio: Gypsum Fibrosum powder (calcined) 3000 parts, Cortex Phellodendri 2500 parts, Radix Glycyrrhizae 1000 parts, 1500 parts of Indigo Naturalis powder, Radix Arnebiae (Radix Lithospermi) 500 parts, Borneolum Syntheticum 500 parts, Pollen Pini 1000 parts.By each finely ground powder of crude drug pulverizer, add appropriate white vaseline, glycerol, be stirred continuously raw material medicated powder, namely prepare Chinese medicine composition cream.Observing from clinical efficacy, the Chinese medicine composition of the present invention has the effect for the treatment of incontinence dermatitis really, and total effective rate is high.

Description

A kind of Chinese medicine composition treating incontinence dermatitis
Technical field
The invention belongs to the Chinese Traditional Medicine application in Modern Nursing field, particularly in the application in treatment patient bedridden in long term complication.
Background technology
Incontinence dermatitis (Incontinence-associateddermatitis, IAD) refers to that skin is long-term or is repeated exposure in urine and feces the inflammation caused, and accompanies or without vesicle and skin injury.This disease is a kind of complication that incontinent patients is common, will also result in the generation of some other disease simultaneously, such as pain, infection and pressure ulcer.Incontinence dermatitis clinical manifestation is: erythema (erythema), edema (edema), dipping (maceration), strip off, the formation of damaged, pimple and vesicle.The border of wound is generally unintelligible, in disperse shape, with pruritus or pain and insecondary fungal infection.Incontinence dermatitis sometimes with one, second phase pressure ulcer clinical manifestation more similar, but the region that incontinence dermatitis occurs is not or not apophysis position, generally in disperse shape and at some skinfold places.Incontinence dermatitis is the complication that long-term bedridden patients is common, inpatient sickness rate 20-27%, long-term care mechanism sickness rate 3.4-7.6%.At present, the sickness rate of incontinence dermatitis has the trend risen year by year, though there being multiple therapy methods, but does not have specific medicament so far.Doctor trained in Western medicine is the ointment such as many uses antibiotic, antiallergic, corticosteroids when treating incontinence dermatitis, how because of the application of high amount of drug and apply irrational phenomenon, and the dysbacteriosis that causes, the appearance of hormone side effect.
Summary of the invention
Present invention solves the technical problem that:
While there is better healing effect, solve the side effect that western medicine incontinence dermatitis is brought.
Technical scheme:
A kind of Chinese medicine composition treating incontinence dermatitis, said composition is made up of the crude drug of following weight ratio: Gypsum Fibrosum powder (calcined) 3000 parts, Cortex Phellodendri 2500 parts, Radix Glycyrrhizae 1000 parts, 1500 parts of Indigo Naturalis powder, Radix Arnebiae (Radix Lithospermi) 500 parts, Borneolum Syntheticum 500 parts, Pollen Pini 1000 parts.
By each finely ground powder of crude drug pulverizer, add appropriate white vaseline, glycerol, be stirred continuously raw material medicated powder, namely prepare Chinese medicine composition cream.
Chinese medicine composition side of the present invention solves:
Gypsum Fibrosum fire forges external for monarch, expelling pus and promoting granulation, removing dampness;Cortex Phellodendri heat clearing and damp drying, eliminating fire and detoxication is minister.Help and disappear rash with Indigo Naturalis, Radix Arnebiae (Radix Lithospermi), Borneolum Syntheticum, Pollen Pini cooling blood and removing stasis, make with effect of Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription.Reaching clearing heat and expelling damp, cooling blood and removing stasis receives the merit of rash.The effect of various raw material of Chinese medicine medicines in the present invention:
One, Gypsum Fibrosum Preparatum
[nature and flavor] are sweet, pungent, puckery, cold, and odorless is lightly seasoned.
[return through] lung, stomach warp.
[function cures mainly] removing dampness, granulation promoting, sore, hemostasis.External treatment ulcer being unable to heal, eczema pruritus, burn due to hot liquid or fire, traumatic hemorrhage.Gypsum Fibrosum grinds external into powder after forging, the above all surgery diseases for the treatment of, has the effect of heat clearing away, convergence, granulation promoting, often closes hydrargrum oxydatum crudum, Cortex Phellodendri, the equivalent use of Indigo Naturalis.
Two, Pollen Pini
[nature and flavor] are sweet, temperature, nontoxic
[return through] enters liver channel of foot-Jueyin, spleen meridian.
[function cures mainly] dispels the wind QI invigorating, removing dampness, hemostasis.Control all skin ulcers and wet rotten, wound hemorrhage.
" herbal classic is met former ": except rheumatism, treatment of smallpox skin ulcer wets rotten.
" medicine will is planted in Jiangsu ": prevention miliaria.Outer as wound hemostasis agent.
" Traditional Chinese Medicine in Sichuan will ": astringing to arrest bleeding.Controlling skin eczema, impetigo wets and rotten does not form a scab.
Three, Indigo Naturalis
[nature and flavor] are salty, cold.
[return through] returns Liver Channel.
[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.
Isatin in Indigo Naturalis is beautiful, and paraplasm granulocyte and oxyphil cell are had effect by indirubin.Can resisting pathogenic microbes, for instance anthrax bacillus, streptococcus pneumoniae, shigella, vibrio cholera, staphylococcus aureus and Staphylococcus albus etc..Indigo Naturalis can also treat epidemic febrile disease intenseness of heat, macule, spits blood, spits blood, and pediatric epilepsy scared, skin ulcer swells, erysipelas, snake bite and insect sting etc.
" key medicine divides agent ": " heat extraction detoxifies, and holding concurrently can removing heat from blood."
Four, Cortex Phellodendri
[nature and flavor] are bitter, cold
[return through] kidney, bladder, large intestine channel
[function cures mainly]: heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever
Clinical practice: 1, damp-heat vaginal discharge, pyretic stranguria, foot swelling and pain in knee, dysentery, jaundice.2, sore swollen toxin, eczema eczema.Feature: kind clear damp-heat in lower-JIAO among heat clearing and damp drying, and kind eliminating fire and detoxication, controls carbuncle sore, eczema, eczema, Shang Shanqing phase fire, reducing the asthenic fever, hectic fever due to YIN-deficiency consumptive fever, sore swollen toxin, eczema pruritus nourishing YIN to lower pathogenic fire, hyperactivity of fire caused by deficiency of YIN
Five, Borneolum Syntheticum
[nature and flavor] gas delicate fragrance, taste is refrigerant arduous, cool.
[return through] returns through entering the heart, lung meridian.
[function cures mainly] this product bitter cold, has the merit of clearing away heat to alleviate pain, detumescence.Swell and ache for skin infection, do not hold back after bursting.This product also has heat-clearing and toxic substances removing, erosion prevention and muscle growing effect.
Six, Radix Arnebiae (Radix Lithospermi)
[nature and flavor] are bitter, cold
[return through] enters percardium, Liver Channel
[function cures mainly] removing heat from blood, invigorates blood circulation, rash of detoxifying.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.Function cures mainly: removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances.Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer
Seven, Radix Glycyrrhizae
[nature and flavor] property is put down, sweet in the mouth
[return through] returns 12 warps.
[function cures mainly] has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic so that the pharmacological action such as anticancer, cure mainly laryngopharynx swelling and pain, cellulitis skin infection Radix Glycyrrhizae agent has antiinflammatory and the function of resistance state reflection.
Beneficial effects of the present invention:
The present invention is pure Chinese medicine ingredients, autoimmune function can be improved, its can cover mucocutaneous on, the various virulence factors of skin surface there is very strong fixing, inhibitory action, and strengthen mucosal barrier defence capability by be combineding with each other with mucosal glycoproteins, thus preventing increasing the weight of of disease damage, reduce the relapse rate of incontinence dermatitis.
And cream is relatively good to the permeability of skin, permeability is good, has refrigerant sensation;Fat content is low, is easier cleaning, will not pollute clothes.
The pharmaceutical composition of the present invention does not enter blood circulation, does not therefore affect liver, kidney, nervus centralis and cardiovascular function, has no side effect, and simple and easy to do, clinical expansion is easy.
Detailed description of the invention
Observe clinical patient 30 example, wherein male 12 examples, female 18 example, all adopt Chinese medicine composition cream of the present invention treatment.
Using method:
First cleaning local skin with warm water, then give painting incontinence dermatitis place outside Chinese medicine composition cream of the present invention, every day 2-3 time, consumption is advisable to smoothen dermatitis happening part every time, keeps local desiccation to breathe freely.Using three courses for the treatment of altogether, a course for the treatment of is 10 days.
Curative effect determinate standard:
According to wound healing process adopts push marking scales, it is divided into following four by score value and final therapeutic effect:
1, recovery from illness: push marks 0 point of dermatitis erythema, edema, and hemorrhage disappearance, erosion are formed a scab, without sense of discomfort.
2, significant effective: push scoring 1-7 divide dermatitis erythema, edema, hemorrhage big portion transference cure, and pain substantially alleviates, and rotten to the corn face is obviously reduced, and sepage reduces (in 3 days).
3, effective: 8-14 point of dermatitis partial symptoms of push scoring alleviates or disappear, pain relief (within 6 days).
4, invalid: push mark 17 points 6 days not unchanged with epithelitis, do not heal.
In this 30 example patient, push score value is respectively such as table 1, and wherein ID is case number:
Table 1push marks
ID 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Push 9 0 13 10 11 9 1 13 12 9 8 14 3 10 11
ID 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Push 14 8 6 14 4 13 0 8 11 5 9 4 12 8 14
There are 2 example push to mark 0 point, reach recovery from illness standard, respectively case 2 and case 22.
Have 6 example push mark 1-7 divide, reach significant effective standard, respectively case 7, case 13, case 18, case 20, case 25, case 27.
22 example push scoring 8-14 are had to divide, reach effective standard, respectively case 1, case 3, case 4, case 5, case 6, case 8, case 9, case 10, case 11, case 12, case 14, case 15, case 16, case 17, case 19, case 21, case 23, case 24, case 26, case 28, case 29, case 30.
All there are not fungal infection, thinning of skin, osteoporosis, acne etc. in all of case.
Therapeutic outcome such as table 2 of 30 example patients, total effective rate reaches 100%:
Table 2 therapeutic outcome
Recovery from illness Significant effective Effectively Invalid Total effective rate
Number of cases (n) 2 6 22 0 100%
Wherein (total effective rate=cure rate+significant effective rate+effective percentage)
Sum up
Observing from clinical efficacy, the Chinese medicine composition of the present invention has the effect for the treatment of incontinence dermatitis really, and total effective rate is high, without the side effect that Western medicine brings.

Claims (2)

1. treat a Chinese medicine composition for incontinence dermatitis, it is characterized by that said composition is made up of the crude drug of following weight ratio: Gypsum Fibrosum powder (calcined) 3000 parts, Cortex Phellodendri 2500 parts, Radix Glycyrrhizae 1000 parts, 1500 parts of Indigo Naturalis powder, Radix Arnebiae (Radix Lithospermi) 500 parts, Borneolum Syntheticum 500 parts, Pollen Pini 1000 parts.
2. Chinese medicine composition as claimed in claim 1, by each finely ground powder of crude drug pulverizer, adds appropriate white vaseline, glycerol, is stirred continuously raw material medicated powder, namely prepares Chinese medicine composition cream.
CN201410458609.3A 2014-09-10 2014-09-10 A kind of Chinese medicine composition treating incontinence dermatitis Active CN104173543B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105250684A (en) * 2015-10-19 2016-01-20 米培燕 Traditional Chinese medicine for treating incontinent dermatitis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101721527A (en) * 2009-09-29 2010-06-09 温志亭 Traditional Chinese medicine jewelry cream and preparation method thereof
CN102258590A (en) * 2011-07-07 2011-11-30 李元文 Calamine and natural indigo ointment and preparation method thereof
CN203342089U (en) * 2013-07-01 2013-12-18 崔证军 Arnebia root oil-immersed spunlace nonwoven fabric paste for external use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101721527A (en) * 2009-09-29 2010-06-09 温志亭 Traditional Chinese medicine jewelry cream and preparation method thereof
CN102258590A (en) * 2011-07-07 2011-11-30 李元文 Calamine and natural indigo ointment and preparation method thereof
CN203342089U (en) * 2013-07-01 2013-12-18 崔证军 Arnebia root oil-immersed spunlace nonwoven fabric paste for external use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
紫草油预防失禁性皮炎的应用研究;须月萍,金友红;《吉林医学》;20131231;第34卷(第26期);5369-5370 *

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