CN103316098B - Rhinitis and nasal polyp liquid medicine and production method thereof - Google Patents

Rhinitis and nasal polyp liquid medicine and production method thereof Download PDF

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Publication number
CN103316098B
CN103316098B CN201310167818.8A CN201310167818A CN103316098B CN 103316098 B CN103316098 B CN 103316098B CN 201310167818 A CN201310167818 A CN 201310167818A CN 103316098 B CN103316098 B CN 103316098B
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grams
liquid medicine
radix
rhinitis
herba selaginellae
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CN103316098A (en
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黄德林
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Abstract

The present invention discloses a rhinitis and nasal polyp liquid medicine and a production method thereof, belongs to the technical field of medicine, and specifically relates to a preparation method of the liquid medicine, wherein disadvantages of inaccurate treatment effect, expensive price and inconvenient promotion use of the current rhinitis treatment drug are overcome with the present invention. The formula of the liquid medicine comprises: 5-7 g of periostracum cicadae, 4-6 g of true lacquertree seed, 7-9 g of lobed kudzuvine root, 9-11 g of licorice root, 4-6 g of divaricate saposhnikovia, 4-6 g of sappsn wood, 18-22 g of moellendorff spikemoss herb, 18-22 g of doederlein spikemoss herb, 14-16 g of giant knotweed rhizome, 4-6 g of coptis chinensis, 2.5-3.5 g of mirabilite, 4-6 g of angelica, honey and a preservative, wherein the honey content is 8-12% of the mass of the liquid medicine, and the preservative content is 0.04-0.06% of the mass of the liquid medicine. The production method comprises: weighing the bulk drugs according to the ratio, adding the drugs to a pot, adding water, decocting for 1 h with mild fire after boiling, filtering the decocted drug liquid, pouring the filtrate into a dish, heating to evaporate partial water, adding mirabilite and honey, uniformly stirring, carrying out filtration concentration to achieve 90-110 ml, adding a preservative, dissolving, and filling in bottles to be spare. The rhinitis and nasal polyp liquid medicine is a pure traditional Chinese medicine preparation, and has characteristics of accurate treatment effect, good effect, low cost, simple preparation, safety and practicality.

Description

A kind of rhinitis nasal polyp liquid medicine and preparation method thereof
Technical field
The invention belongs to medical technical field, be specifically related to prescription composition of rhinitis nasal polyp liquid medicine and preparation method thereof.
Background technology
Rhinitis refers to the inflammation of nasal membrane and submucous tissue, shows as hyperemia or edema submucous tissue hypertrophy, the symptom such as patient often occurs nasal obstruction, watery nasal discharge, plays spray, rhinocnesmus, throat's discomfort, cough.It is because of acute or chronic nasal mucosa be subject to virus, courses of infection or irritating effect impaired due to, often there is dizziness, headache in patient, easily tired, hypomnesis, long-term pathological changes can be brought for hypoxgia state to health, affect other organ normal function metabolism and produce pathological changes, as acute otitis media, sinusitis, chronic pharyngolaryngitis etc., so rhinitis is also the potential root of various diseases.
Rhinitis on market and the drug for treating rhinitis of having authorized recently then, practical value is little, part medication effect is fuzzy, slightly resultful part medicine is expensive or preparation process is complicated, be unfavorable for that large area is universal, feature of the present invention is: cost is low, successful is stable, safety simple, easy to use is enriched, made in medicine source, side effect is few.Chronic rhinitis is repeatedly that acute inflammation could not thoroughly be cured and change into chronic rhinitis, nasal mucosa swelling vascular compression, blood flow be obstructed metabolism produce obstacle, focus can not effectively be repaired, inflammation is persistent and cause mucous epithelium cilium to come off, become multiple layer cube rawhide, by edema, then be there is proliferation of fibrous tissue and made pachymucosa in tela submucosa, of a specified duration can be Fructus Mori shape or Polypoid changes, periosteum and osseous tissue hypertrophy, concha nasalis sclerotin is also loose change, the obvious hypertrophy of concha nasalis inferior or concha nasalis inferior and middle nasal concha are all loose, often cause nasal cavity obstruction etc.
The efficacy effect of each group medicine: 1. Lignum Sappan, Semen toxicodendri verniciflni, Mirabilitum, Cicadae move back, Radix Saposhnikoviae, this group medicine plays to be moisturized, softening the hard mass, promoting the circulation of blood, removing blood stasis with potent drugs, removing food stagnancy, goes wind, pain relieving, is intended to the digestion of the pathological product of intralesional to expel, and to focus, provides repairing condition.Chinese medicine Lignum Sappan sweet in the mouth, salty, pungent, property is flat, promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving; Semen toxicodendri verniciflni is warm in nature, promoting blood circulation and hemostasis, antalgic; Mirabilitum bitter in the mouth, salty, warm in nature, ward off dirty wash turbid, the removing mass of assaulting fortified position, diuretic removing the relative excess, removing toxic substances and promoting subsidence of swelling; Cicadae moves back sweet salty, cool in nature, loose wind heat, and lung qi dispersing, determines convulsion; Radix Saposhnikoviae is pungent, sweet, slightly warm in nature, expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.2. Rhizoma Polygoni Cuspidati, Herba Selaginellae Doederleinii, Herba Selaginellae Moellendorfii, Rhizoma Coptidis, that this group medicine plays is antibacterial, antiviral, anticancer, prevent long-term inflammation to cause focus cytopathy.The micro-hardship of Rhizoma Polygoni Cuspidati, cold nature, heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy; Herba Selaginellae Doederleinii taste is micro-puckery, warm in nature, dispel the wind, and cold expelling, detumescence; Herba Selaginellae Moellendorfii acrid in the mouth, micro-sweet, property is flat, clearing away heat-damp and promoting diuresis, hemostasis; Rhizoma Coptidis bitter in the mouth, cold in nature, nontoxic, heat clearing and damp drying, eliminating fire and detoxication.3. Radix Puerariae, Radix Angelicae Sinensis, this group medicine plays increases blood flow and protection blood vessel reinforcement tissue metabolism to blood circulation, is beneficial to reparation.Radix Puerariae sweet in the mouth, pungent, cool in nature, induce sweat and bring down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal; Radix Angelicae Sinensis sweet in the mouth; Pungent; Bitter; Warm in nature, enrich blood, to invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Radix Glycyrrhizae plays antiinflammatory and antiallergic action, inflammation is effectively controlled in adrenal cortex effect, improves clinical symptoms.Radix Glycyrrhizae sweet in the mouth, property is flat, nontoxic, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Mel plays and promotes mucomembranous cell and wound tissue to repair.Mel sweet in the mouth, property is flat, harmonizing the spleen and stomach, relieving spasm to stop pain, nourishing the lung to arrest cough, loosening bowel to relieve constipation, skin moistening granulation promoting, removing toxic substances.
Summary of the invention
The object of this invention is to provide a kind of determined curative effect, effective, cost is low, makes simply safe and practical pure Chinese medicine rhinitis nasal polyp liquid medicine and preparation method thereof.
The present invention is achieved by following scheme:
A kind of prescription composition of rhinitis nasal polyp liquid medicine is: Cicadae moves back 8~12% and the antiseptic that 5~7 grams, 4~6 grams of Semen toxicodendri verniciflni, 7~9 grams of Radix Puerariaes, 9~11 grams, Radix Glycyrrhizae, 4~6 grams of Radix Saposhnikoviaes, 4~6 grams of Lignum Sappans, 18~22 grams of Herba Selaginellae Moellendorfiis, 18~22 grams of Herba Selaginellae Doederleiniis, 14~16 grams of Rhizoma Polygoni Cuspidati, 4~6 grams of Rhizoma Coptidis, 2.5~3.5 grams of Mirabilitums, 4~6 grams of Radix Angelicae Sinensis, Mel account for liquid medicine quality and accounts for 0.04~0.06% of liquid medicine quality.
Preferably, prescription composition is: Cicadae moves back 10% and the antiseptic that 6 grams, 5 grams of Semen toxicodendri verniciflni, 8 grams of Radix Puerariaes, 10 grams, Radix Glycyrrhizae, 5 grams of Radix Saposhnikoviaes, 5 grams of Lignum Sappans, 20 grams of Herba Selaginellae Moellendorfiis, 20 grams of Herba Selaginellae Doederleiniis, 15 grams of Rhizoma Polygoni Cuspidati, 5 grams of Rhizoma Coptidis, 3 grams of Mirabilitums, 5 grams of Radix Angelicae Sinensis, Mel account for liquid medicine quality and accounts for 0.05% of liquid medicine quality.
A kind of manufacture method of rhinitis nasal polyp liquid medicine is as follows:
Take Cicadae move back 4~6 grams of 5~7 grams, 4~6 grams of Semen toxicodendri verniciflni, 7~9 grams of Radix Puerariaes, 9~11 grams, Radix Glycyrrhizae, 4~6 grams of Radix Saposhnikoviaes, 4~6 grams of Lignum Sappans, 18~22 grams of Herba Selaginellae Moellendorfiis, 18~22 grams of Herba Selaginellae Doederleiniis, 14~16 grams of Rhizoma Polygoni Cuspidati, 4~6 grams of Rhizoma Coptidis and Radix Angelicae Sinensis totally ten one kinds of medicines put into pot and add water to super powder one-inch, boil latter 1 hour at a simmer, after the liquid medicine filter of decocting is poured in a dish and is put well, add water to again in the pot of medicinal residues, water will exceed powder one-inch, decoction is the same, twice totally; Then getting the liquid medicine hybrid filtering of decocting for twice removes slag, get it filled and add 2.5~3.5 grams of Mirabilitums, Mel after water boiler portion and account for 8~12% of liquid medicine quality and stir to refilter and be concentrated into 90~110 milliliters, adding preservative agent accounts for 0.04~0.06% of liquid medicine quality, and after dissolving, sub-bottle fill is standby.
Beneficial effect of the present invention: cost is low, successful is stable, and medicine source is abundant, makes simply, safety easy to use, side effect is few, has the very wide prospect of marketing.
The specific embodiment
Below in conjunction with concrete embodiment, the present invention is described in further detail, to make those skilled in the art can implement according to this with reference to description word.
Embodiment 1:
Take Cicadae move back 5 grams of 6 grams, 5 grams of Semen toxicodendri verniciflni, 8 grams of Radix Puerariaes, 10 grams, Radix Glycyrrhizae, 5 grams of Radix Saposhnikoviaes, 5 grams of Lignum Sappans, 20 grams of Herba Selaginellae Moellendorfiis, 20 grams of Herba Selaginellae Doederleiniis, 15 grams of Rhizoma Polygoni Cuspidati, 5 grams of Rhizoma Coptidis and Radix Angelicae Sinensis totally ten one kinds of medicines put into pot and add water to super powder one-inch, boil latter 1 hour at a simmer, after the liquid medicine filter of decocting is poured in a dish and is put well, add water to again in the pot of medicinal residues, water will exceed powder one-inch, decoction is the same, twice totally; Then get the liquid medicine hybrid filtering of decocting for twice and remove slag, add 3 grams of Mirabilitums, Mel and account for 10% of liquid medicine quality and stir to refilter and be concentrated into 100 milliliters after the water boiler portion of getting it filled, adding preservative agent accounts for 0.05% of liquid medicine quality, and after dissolving, sub-bottle fill is standby.Usage: collunarium, each 2; Every day three times.Child can use with water for injection two-fold dilution.
Embodiment 2:
Take Cicadae move back 4 grams of 5 grams, 4 grams of Semen toxicodendri verniciflni, 7 grams of Radix Puerariaes, 9 grams, Radix Glycyrrhizae, 4 grams of Radix Saposhnikoviaes, 4 grams of Lignum Sappans, 18 grams of Herba Selaginellae Moellendorfiis, 18 grams of Herba Selaginellae Doederleiniis, 14 grams of Rhizoma Polygoni Cuspidati, 4 grams of Rhizoma Coptidis and Radix Angelicae Sinensis totally ten one kinds of medicines put into pot and add water to super powder one-inch, boil latter 1 hour at a simmer, after the liquid medicine filter of decocting is poured in a dish and is put well, add water to again in the pot of medicinal residues, water will exceed powder one-inch, decoction is the same, twice totally; Then get the liquid medicine hybrid filtering of decocting for twice and remove slag, add 2.5 grams of Mirabilitums, Mel and account for 8% of liquid medicine quality and stir to refilter and be concentrated into 90 milliliters after the water boiler portion of getting it filled, adding preservative agent accounts for 0.04% of liquid medicine quality, and after dissolving, sub-bottle fill is standby.Usage: collunarium, each 2; Every day three times.Child can use with water for injection two-fold dilution.
Embodiment 3:
Take Cicadae move back 6 grams of 7 grams, 6 grams of Semen toxicodendri verniciflni, 9 grams of Radix Puerariaes, 11 grams, Radix Glycyrrhizae, 6 grams of Radix Saposhnikoviaes, 6 grams of Lignum Sappans, 22 grams of Herba Selaginellae Moellendorfiis, 22 grams of Herba Selaginellae Doederleiniis, 16 grams of Rhizoma Polygoni Cuspidati, 6 grams of Rhizoma Coptidis and Radix Angelicae Sinensis totally ten one kinds of medicines put into pot and add water to super powder one-inch, boil latter 1 hour at a simmer, after the liquid medicine filter of decocting is poured in a dish and is put well, add water to again in the pot of medicinal residues, water will exceed powder one-inch, decoction is the same, twice totally; Then get the liquid medicine hybrid filtering of decocting for twice and remove slag, add 3 grams of Mirabilitums, Mel and account for 12% of liquid medicine quality and stir to refilter and be concentrated into 110 milliliters after the water boiler portion of getting it filled, adding preservative agent accounts for 0.05% of liquid medicine quality, and after dissolving, sub-bottle fill is standby.
Model case: example 1 beam, female, 13 years old, family was in Si Lena merit village, Ningming County, symptom is that nasal obstruction, tinnitus, two nasal mucosa are dry, congested, in JIUYUE in 1992, within 20th, come to cure, be diagnosed as general rhinitis, with this patent drugs water droplet nose, every day three times, each two, 1 bottle 10 milliliters these liquid medicine of medication are cured, so far not recurrence.Example 2 Baos, man, 20 years old, stays in the friend of Si Leyoufu village, Ningming County group village, symptom for nasal obstruction dizzy sneeze, two nasal mucosa edema, the white nose epicoele of state polyp hypertrophy secretions many, on May 13rd, 1992, cure, be diagnosed as allergic rhinitis, nasal polyp, with this patent drugs water droplet nose, every day three times, each two, with 10 bottles 10 milliliters these liquid medicine, cure, do not recur so far.Example 3 Huangs, female, 24 years old, live tectogene Xin Lu street, on August 16th, 1993, cure, be diagnosed as nasal polyp, with this patent drugs water droplet nose, every day three times, each two, with 10 bottles 10 milliliters these liquid medicine, cure, do not recur so far.Example 4 is foretold certain, female, and 56 years old, live Ningming Xin Jie, cure February 9 nineteen ninety-five, is diagnosed as general rhinitis, with this patent drugs water droplet nose, every day three times, each two, with 2 bottles 10 milliliters these liquid medicine, cure, do not recur so far.Example 5 what certain, female, 20 years old, in tectogene department store, on April 23rd, 2010, cure, be diagnosed as general rhinitis, with this patent drugs water droplet nose, every day three times, each two, with 3 bottles 10 milliliters these liquid medicine healings, do not recur so far.Example 6 Lee, man, 42 years old, in tectogene sugar refinery, on June 6th, 2011, cure, be diagnosed as allergic rhinitis, with this patent drugs water droplet nose, every day three times, each two, with 4 bottles 10 milliliters these liquid medicine healings.
Treatment diagnostic criteria:
Cure: rhinoscopy, nasal mucosa swelling is disappeared, and without mucus or purulent secretion, mucosa is salmon pink, and nasal cavity spaciousness is smooth, and patient's subjective symptoms disappears, and ventilation is good.
Take a turn for the better: after patient's medication, feel that symptom alleviates, secretions is few before than medication, good before ventilation ratio medication, rhinoscopy mucous hyperemia turns red or talks redness, Fructus Mori shape or Polypoid changes more tiny by dark red.
Be clearly better: between the upper healing state that approaches between the two.
Invalid: before and after medication, all equally not change.

Claims (3)

1. a rhinitis nasal polyp liquid medicine, it is characterized in that, this liquid medicine is prepared from by following raw material: Cicadae moves back 8~12% and the antiseptic that 5~7 grams, 4~6 grams of Semen toxicodendri verniciflni, 7~9 grams of Radix Puerariaes, 9~11 grams, Radix Glycyrrhizae, 4~6 grams of Radix Saposhnikoviaes, 4~6 grams of Lignum Sappans, 18~22 grams of Herba Selaginellae Moellendorfiis, 18~22 grams of Herba Selaginellae Doederleiniis, 14~16 grams of Rhizoma Polygoni Cuspidati, 4~6 grams of Rhizoma Coptidis, 2.5~3.5 grams of Mirabilitums, 4~6 grams of Radix Angelicae Sinensis, Mel account for liquid medicine quality and accounts for 0.04~0.06% of liquid medicine quality.
2. a kind of rhinitis nasal polyp liquid medicine according to claim 1, it is characterized in that, Cicadae moves back 10% and the antiseptic that 6 grams, 5 grams of Semen toxicodendri verniciflni, 8 grams of Radix Puerariaes, 10 grams, Radix Glycyrrhizae, 5 grams of Radix Saposhnikoviaes, 5 grams of Lignum Sappans, 20 grams of Herba Selaginellae Moellendorfiis, 20 grams of Herba Selaginellae Doederleiniis, 15 grams of Rhizoma Polygoni Cuspidati, 5 grams of Rhizoma Coptidis, 3 grams of Mirabilitums, 5 grams of Radix Angelicae Sinensis, Mel account for liquid medicine quality and accounts for 0.05% of liquid medicine quality.
3. the manufacture method of a rhinitis nasal polyp liquid medicine, it is characterized in that, take Cicadae move back 4~6 grams of 5~7 grams, 4~6 grams of Semen toxicodendri verniciflni, 7~9 grams of Radix Puerariaes, 9~11 grams, Radix Glycyrrhizae, 4~6 grams of Radix Saposhnikoviaes, 4~6 grams of Lignum Sappans, 18~22 grams of Herba Selaginellae Moellendorfiis, 18~22 grams of Herba Selaginellae Doederleiniis, 14~16 grams of Rhizoma Polygoni Cuspidati, 4~6 grams of Rhizoma Coptidis, Radix Angelicae Sinensis totally ten one kinds of medicines put into pot and add water to super powder one-inch, boil latter 1 hour at a simmer, after the liquid medicine filter of decocting is poured in a dish and is put well, add water to again in the pot of medicinal residues, water will exceed powder one-inch, decoction is the same, twice totally; Then getting the liquid medicine hybrid filtering of decocting for twice removes slag, get it filled and add 2.5~3.5 grams of Mirabilitums, Mel after water boiler portion and account for 8~12% of liquid medicine quality and stir to refilter and be concentrated into 90~110 milliliters, adding preservative agent accounts for 0.04~0.06% of liquid medicine quality, and after dissolving, sub-bottle fill is standby.
CN201310167818.8A 2013-05-08 2013-05-08 Rhinitis and nasal polyp liquid medicine and production method thereof Expired - Fee Related CN103316098B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1174072A (en) * 1997-07-12 1998-02-25 迟经惠 Medicine for eliminating rhinitis and nasal polyp
CN102784255A (en) * 2011-05-18 2012-11-21 吴东红 Traditional Chinese medicine formula for treating allergic rhinitis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1174072A (en) * 1997-07-12 1998-02-25 迟经惠 Medicine for eliminating rhinitis and nasal polyp
CN102784255A (en) * 2011-05-18 2012-11-21 吴东红 Traditional Chinese medicine formula for treating allergic rhinitis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
中医药治疗慢性鼻窦炎复方分析和证治规律研究;杨宇华;《河北中医》;20070228;第29卷(第02期);175-177 *
孙明瑜等.慢性鼻窦炎的中医药治疗研究.《辽宁中医学院学报》.2000,第2卷(第01期),46-47.
慢性鼻窦炎的中医药治疗研究;孙明瑜等;《辽宁中医学院学报》;20000331;第2卷(第01期);46-47 *
杨宇华.中医药治疗慢性鼻窦炎复方分析和证治规律研究.《河北中医》.2007,第29卷(第02期),175-177.

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