CN101716286B - Traditional Chinese medicine composition for treating hemorrhagic stroke - Google Patents
Traditional Chinese medicine composition for treating hemorrhagic stroke Download PDFInfo
- Publication number
- CN101716286B CN101716286B CN2009102275205A CN200910227520A CN101716286B CN 101716286 B CN101716286 B CN 101716286B CN 2009102275205 A CN2009102275205 A CN 2009102275205A CN 200910227520 A CN200910227520 A CN 200910227520A CN 101716286 B CN101716286 B CN 101716286B
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- cerebral
- medicine composition
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for adjuvantly treating the hemorrhagic stroke. The traditional Chinese medicine composition is prepared from the following raw medicine materials in parts by weight: 3-10 parts of pseudo-ginseng, 3-10 parts of cattail pollen, 3-10 parts of rhizoma bletillae, 3-6 parts ofcarbonized hair, 2-5 parts of scorpion, 3-10 parts of rhizoma gastrodiae, 10-15 parts of uncaria rhynchophylla, 15-20 parts of sea-ear shell, 10-15 parts of chrysanthemum, 1-3 parts of antelope horn,1.5-6 parts of arisaema cum bile and 10-15 parts of plantain seed. The composition has the double regulating effects of stopping bleeding and dissolving stasis, not only can stop bleeding without stasis, but also can dissolve the stasis without bleeding, thereby effectively making up for the defect that western medicine is easy to cause thrombus during stopping bleeding. The composition is used for the auxiliary treatment of the hemorrhagic stroke caused by cerebral arteriole bleeding because of high blood pressure, cerebral arteriosclerosis, cerebral arteritis, cerebral bottom aneurysm or cerebral artery and vein deformity, and the like and has unexpected good effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition of auxiliary treatment hemorrhagic cerebral apoplexy.
Background technology
Hemorrhagic cerebral apoplexy belongs to motherland's medical science " apoplexy " category.The sick beginning of apoplexy one sees " interior warp ", and titles such as coma, emotional syncope, hemiplegia, hemiplegia, miliaria wind are arranged.Its pathogenesis is the angry or burbulent wine of being worried, addiction to greasy and sweet foods savoury, and interior wind, fire, expectorant, the stasis of blood of making causes that liver-yang is opened cruelly, QI and blood is contrary disorderly, hold the phlegm-fire upper punch under the arm, causes blood oozing from the body openings or subcuta neous tissue brain arteries and veins.Clinical in dizziness headache or sudden faint, syncope, mouthful eye
Tiltedly, hemiplegia, dysphonia or aphasia etc. are primary symptom.
Hemorrhagic cerebral apoplexy, comprise that brain essence is hemorrhage, cerebellar hemorrhage, subarachnoid hemorrhage etc., account for about 40% of acute cerebral stroke, its mortality rate, disability rate are high, and when using the western medicine primary disease merely, can only adopt supporting treatment to the ill, effect is not remarkable, moreover in the acute hemorrhage phase, if give hemorrhage, as 6-aminocaprolc acid, not only uncertain therapeutic efficacy is cut, and can cause venous thrombosis.Though there are a lot of patients to keep life, stay a maimed health, bring very big burden for society and family.
Summary of the invention
For overcoming the deficiencies in the prior art part, the object of the present invention is to provide a kind of Chinese medicine composition of auxiliary treatment hemorrhagic cerebral apoplexy, said composition has the dual regulation of hemostasis, dissipating blood stasis, can stop blooding and does not stay the stasis of blood, again can blood stasis dispelling and unlikely hemorrhage.
For achieving the above object, the technical scheme taked of the present invention is as follows:
A kind of Chinese medicine composition of auxiliary treatment hemorrhagic cerebral apoplexy, described Chinese medicine is made by each crude drug of following portions by weight:
3～10 parts of Radix Notoginseng, 3～10 parts of Pollen Typhaes, 3～10 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 3～6 parts of Crinis Carbonisatus, 2～5 parts of Scorpios, 3～10 parts in Rhizoma Gastrodiae, 10～15 parts of Ramulus Uncariae Cum Uncis, 15～20 parts of Concha Haliotidis, 10～15 parts of Flos Chrysanthemis, 1～3 part of Cornu Saigae Tataricae, 1.5～6 parts of Arisaema Cum Bile, 10～15 parts of Semen Plantaginiss.
Further, the parts by weight of described each crude drug are preferably:
10 parts of Radix Notoginseng, 10 parts of Pollen Typhaes, 10 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 6 parts of Crinis Carbonisatus, 5 parts of Scorpios, 10 parts in Rhizoma Gastrodiae, 10 parts of Ramulus Uncariae Cum Uncis, 15 parts of Concha Haliotidis, 10 parts of Flos Chrysanthemis, 1.5 parts of Cornu Saigae Tataricae, 3 parts of Arisaema Cum Bile, 15 parts of Semen Plantaginiss.
Described Chinese medicine composition technology is routinely made decoct, pill or capsule.
Preparation method and using method:
Acute stage, with being decocted in water for oral dose or nasal feeding: in by weight/volume, take by weighing Radix Notoginseng 3～10g, Pollen Typhae 3～10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3～10g, Crinis Carbonisatus 3～6g, Scorpio 2～5g, Rhizoma Gastrodiae 3～10g, Ramulus Uncariae Cum Uncis 10～15g, Concha Haliotidis 15～20g, Flos Chrysanthemi 10～15g, Cornu Saigae Tataricae 1～3g, Arisaema Cum Bile 1.5～6g, Semen Plantaginis 10～15g, then this 12 flavor Chinese medicine is put into marmite, first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, 30 minutes at a simmer of reuse, the about 350ml of taking liquid; Second fries in shallow oil and adds water 500ml, boils earlier the back reuse with high heat 25 minutes at a simmer, the about 350ml of taking liquid; Two boil medicine liquid mix after clothes at twice, morning and evening service once, decoction being taken warmly or nasal feeding.
Recovery Phase of diseases: take by weighing Radix Notoginseng 3～10g, Pollen Typhae 3～10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3～10g, Crinis Carbonisatus 3～6g, Scorpio 2～5g, Rhizoma Gastrodiae 3～10g, Ramulus Uncariae Cum Uncis 10～15g, Concha Haliotidis 15～20g, Flos Chrysanthemi 10～15g, Cornu Saigae Tataricae 1～3g, Arisaema Cum Bile 1.5～6g, Semen Plantaginis 10～15g by weight ratio, then this 12 flavor Chinese medicine is pulverized the back and cross 100 orders or 120 mesh sieves, after making superfine medicated powder: 1. medicated powder and honey are made honeyed pill in 1: 1.5 ratio, every ball 3g obeys 6g, every day at every turn and obeys twice; 2. the Capsules of medicated powder being packed into, is obeyed 6, every day three times at every 0.3g at every turn.
Pharmacology of the present invention is as follows:
Radix Notoginseng: not only stopped blooding, but also the blood that looses, and be used for the various internal and external haemorrhage diseases of human body.Radix Notoginseng can stop blooding, again can dissipating blood stasis, drug effect is distinguished, hemostasis is arranged and do not stay the stasis of blood, blood stasis dispelling and do not hinder just characteristics, really be mass formed by blood stasis good medicine.It is better to join the Crinis Carbonisatus curative effect.As " Records of Tradition Chinese and Western Medicine in Combination " " Bleeding-Stopping Bolus ", Compendium of Material Medica " Radix Notoginseng hemostasis dissipating blood stasis ... cure mainly bruise ".Drug research proves in recent years: Radix Notoginseng styptic activity composition is β-N-diacid acyl group-L-α, β-diaminopropionic acid, has anastalsis, can significantly shorten the rabbit clotting time; Radix Notoginseng blood stasis dispelling composition is arasaponin, flavonoid glycoside ..., remarkable anticoagulation is arranged, the energy anticoagulant promotes fibrinolytic, and whole blood viscosity is descended; Radix Notoginseng can increase the anesthetized animal coronary flow, reduces myocardial oxygen consumption, promotes arteria coronaria infarct side to prop up circulation and forms, increase cardiac output, and antiarrhythmic effect is arranged, existing anastalsis, do not influence the blood circulation of arteria coronaria again, be the drug of first choice of treatment hemorrhagic cerebral apoplexy.
Pollen Typhae: hemostasis, blood stasis dispelling, diuresis is used for various internal and external haemorrhage diseases.Pollen Typhae can stop blooding, again can blood stasis dispelling, its diuresis is useful to reducing intracranial pressure.No matter Pollen Typhae belongs to the cold heat that belongs to hemorrhage, has or not blood stasis, all can use it with the disease compatibility, but suitable especially with true folder stasis of blood person.In recent years drug research proves: Pollen Typhae contains compositions such as flavone, Palmic acid, isorhamnetin, sterol phenols, and the promotion Blood clotting is arranged, and the rabbit clotting time is obviously shortened; Pollen Tyjphae prevents the atherosclerotic effect of rabbit bait, can suppress the intestinal absorption cholesterol, changes lipid composition, and effects such as blood pressure lowering, expansion blood vessel, increase coronary flow are arranged.
Pseudobulbus Bletillae (Rhizoma Bletillae): astringing to arrest bleeding, be used for inside and outside all hemorrhages, be the astringing to arrest bleeding key medicine, anastalsis is good.Pseudobulbus Bletillae (Rhizoma Bletillae) and Radix Notoginseng compatibility both can be strengthened anastalsis, and unlikely again blood stasis is detained.In recent years drug research proves: the mucous matter 56.7%～60.5% of Pseudobulbus Bletillae (Rhizoma Bletillae), multiple polysaccharide etc. is wherein arranged, and the clotting time of shortening is arranged and suppress the fibrinolytic effect, have good anastalsis.
Crinis Carbonisatus: astringing to arrest bleeding, the blood stasis dispelling diuresis, the astringing to arrest bleeding effect of existing similar charred Petiolus Trachycarpi again can dissipating blood stasis, so there is not the trouble of staying the stasis of blood, compatibility Radix Notoginseng effect is more excellent.
Scorpio: the master goes into Liver Channel, has both calmed down liver-wind, and expel wind to dredge collateral has good relieving convulsion effect again, and with Cornu Saigae Tataricae, Rhizoma Gastrodiae, the Ramulus Uncariae Cum Uncis compatibility strengthens suppressing the hyperactive liver to relieve the wind syndrome, and the merit of town's liver YANG hyperactivity suppressing can be used for diseases such as hyperpyrexia, coma, contracture.In recent years drug research proves: Scorpio preserved material and decoct all have remarkable persistent hypotensive effect, and clear-headed animal is had obvious sedation.
Rhizoma Gastrodiae: main go into Liver Channel, both ceased liver-wind, so suppressing the hyperactive liver sun again is for controlling dizziness and headache good medicine.Rhizoma Gastrodiae must with the armillaria mellea symbiosis, form extremely close nutrition relationship with armillaria mellea in its growth and breeding process.In recent years studies have shown that: Rhizoma Gastrodiae can reduce peripheral blood vessel and effects such as coronary vascular resistance, blood pressure lowering.The solid culture material of armillaria mellea has pharmacological action similar to Rhizoma Gastrodiae and clinical efficacy, so armillaria mellea can be medicinal for Rhizoma Gastrodiae.In recent years use armillaria mellea sheet treatment hyperlipemia, serum cholesterol, serum levels of triglyceride etc. are obviously descended, systolic pressure or diastolic pressure also have decline in various degree simultaneously.Therefore, Rhizoma Gastrodiae also has the effect of blood fat reducing.
Ramulus Uncariae Cum Uncis: go into Liver Channel, both removing heat from the liver, the suppressing the hyperactive liver sun is used for excessive rising of liver-YANG headache, dizziness again, and compatibility Rhizoma Gastrodiae, Concha Haliotidis, Flos Chrysanthemi curative effect are better.In recent years studies have shown that: Ramulus Uncariae Cum Uncis contains Ramulus Uncariae cum Uncis alkali, isorhynchophylline, useful 20% Ramulus Uncariae Cum Uncis decoct treatment hypertension, and it has gentle hypotensive effect.
Concha Haliotidis: specially go into Liver Channel, both suppressing the hyperactive liver sun, removing heat from the liver is the key medicine of cool liver town liver again.Control the headache of overabundant liver-fire with Ramulus Uncariae Cum Uncis, Flos Chrysanthemi compatibility, fidgety irritability is better." Records of Tradition Chinese and Western Medicine in Combination " " Concha Haliotidis, little salty, the slightly cool in nature of flavor are the key medicine of cool liver town liver ... can cool liver hold concurrently for it and can press down liver, ache so be apt to control in the brain hyperemia, do dizzy.Therefore disease polyphyly irritability, liver-fire are held the blood upper punch under the arm also.”
Flos Chrysanthemi: cold in naturely go into Liver Channel, can the heat clearing away suppressing the hyperactive liver, thus with Concha Haliotidis with having a headache dizzy with the rising for the treatment of the liver sun.In recent years studies have shown that: the Flos Chrysanthemi preparation, coronary artery dilator is arranged, coronary blood flow increasing, and hypotensive effect is arranged.
Cornu Saigae Tataricae: significant suppressing the hyperactive liver and subsiding YANG effect is arranged, with same usefulness of suppressing the hyperactive liver and subsiding YANG medicine such as Concha Haliotidis, Flos Chrysanthemi, Rhizoma Gastrodiaes, the dizzy more remarkable treatment effect for the treatment of the liver sun rising.In recent years studies have shown that: Cornu Saigae Tataricae phosphoric acid calcium, keratin etc." book on Chinese herbal medicine is new again ": " tranquilizing mind, only night sweat, consumer edema, blood stasis removing blood, tissue regeneration promoting blood, the pathogenic fire reducing therapeutic method to keep the adverse QI flowing downwards, the relieving restlessness of quenching the thirst.”
Arisaema Cum Bile (another name Arisaema Cum Bile): return the liver and gall warp, both removing heat-phlegm, dispelling wind and relieving convulsion again cures mainly apoplexy, wind syndrome of head, disease such as dizzy.
Semen Plantaginis: diuresis eliminating dampness by diuresis, liver heat removing and eyesight improving, remarkable diuresis is arranged.Control hypertension and can fry in shallow oil soup for tea-drinking with Semen Plantaginis.
More than all medicine compatibilities, gather the effect of suppressing the hyperactive liver and subsiding YANG, hemostasia and dissipation blood stasis altogether, be used for the treatment of because of liver-yang rises suddenly and sharply, sun rises pneumatic, QI and blood superinverse, hold under the arm and cover blood oozing from the body openings or subcuta neous tissue brain arteries and veins due to the clear key on the phlegm-fire, disease is seen dizziness headache, even the soldier so faints, syncope, mouthful eye
Tiltedly, hemiplegia, hemianesthesia, dysphonia or wait disease in silence.
The present composition has the dual regulation of hemostasis, dissipating blood stasis, can stop blooding and does not stay the stasis of blood, again can blood stasis dispelling and unlikely hemorrhage, and remedy the Western medicine hemostasis effectively and easily caused thrombotic drawback.Clinical practice for many years proves, the present composition is used for all having obtained beyond thought good result because of hypertension causes the auxiliary treatment that the hemorrhage and cerebral arteriosclerosis of brain small artery, cerebral arteritis, brain bottom aneurysm or brain artery and vein deformity etc. cause hemorrhagic cerebral apoplexy.
The specific embodiment
Below in conjunction with specific embodiment technical scheme of the present invention is done to introduce in detail further, but protection scope of the present invention is not limited thereto:
Embodiment 1
Radix Notoginseng 3g, Pollen Typhae 6g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g, Crinis Carbonisatus 4g, Scorpio 2g, Rhizoma Gastrodiae 3g, Ramulus Uncariae Cum Uncis 13g, Concha Haliotidis 20g, Flos Chrysanthemi 13g, Cornu Saigae Tataricae 3g, Arisaema Cum Bile 6g, Semen Plantaginis 13g.
Acute stage,, with being decocted in water for oral dose or nasal feeding: above-mentioned 12 flavor Chinese medicines are put into marmite, and first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, and 30 minutes at a simmer of reuse, the about 350ml of taking liquid; Second fries in shallow oil and adds water 500ml, boils earlier the back reuse with high heat 25 minutes at a simmer, the about 350ml of taking liquid; Two boil medicine liquid mix after clothes at twice, morning and evening service once, decoction being taken warmly or nasal feeding.
Recovery Phase of diseases: above-mentioned 12 flavor Chinese medicines are pulverized the back and are crossed 100 orders or 120 mesh sieves, make superfine medicated powder after: 1. medicated powder and honey are made honeyed pill by 1: 1.5 weight ratio, every ball 3g obeys 6g, every day at every turn and obeys twice; 2. the Capsules of medicated powder being packed into, is obeyed 6, every day three times at every 0.3g at every turn.
Embodiment 2
Radix Notoginseng 10g, Pollen Typhae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Crinis Carbonisatus 6g, Scorpio 5g, Rhizoma Gastrodiae 10g, Ramulus Uncariae Cum Uncis 10g, Concha Haliotidis 15g, Flos Chrysanthemi 10g, Cornu Saigae Tataricae 1.5g, Arisaema Cum Bile 3g, Semen Plantaginis 15g.
Acute stage,, with being decocted in water for oral dose or nasal feeding: above-mentioned 12 flavor Chinese medicines are put into marmite, and first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, and 30 minutes at a simmer of reuse, the about 350ml of taking liquid; Second fries in shallow oil and adds water 500ml, boils earlier the back reuse with high heat 25 minutes at a simmer, the about 350ml of taking liquid; Two boil medicine liquid mix after clothes at twice, morning and evening service once, decoction being taken warmly or nasal feeding.
Recovery Phase of diseases: above-mentioned 12 flavor Chinese medicines are pulverized the back and are crossed 100 orders or 120 mesh sieves, make superfine medicated powder after: 1. medicated powder and honey are made honeyed pill by 1: 1.5 weight ratio, every ball 3g obeys 6g, every day at every turn and obeys twice; 2. the Capsules of medicated powder being packed into, is obeyed 6, every day three times at every 0.3g at every turn.
Embodiment 3
Radix Notoginseng 7g, Pollen Typhae 3g, Pseudobulbus Bletillae (Rhizoma Bletillae) 6g, Crinis Carbonisatus 3g, Scorpio 3.5g, Rhizoma Gastrodiae 7g, Ramulus Uncariae Cum Uncis 15g, Concha Haliotidis 17g, Flos Chrysanthemi 15g, Cornu Saigae Tataricae 1g, Arisaema Cum Bile 1.5g, Semen Plantaginis 10g.
Acute stage,, with being decocted in water for oral dose or nasal feeding: above-mentioned 12 flavor Chinese medicines are put into marmite, and first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, and 30 minutes at a simmer of reuse, the about 350ml of taking liquid; Second fries in shallow oil and adds water 500ml, boils earlier the back reuse with high heat 25 minutes at a simmer, the about 350ml of taking liquid; Two boil medicine liquid mix after clothes at twice, morning and evening service once, decoction being taken warmly or nasal feeding.
Recovery Phase of diseases: above-mentioned 12 flavor Chinese medicines are pulverized the back and are crossed 100 orders or 120 mesh sieves, make superfine medicated powder after: 1. medicated powder and honey are made honeyed pill by 1: 1.5 weight ratio, every ball 3g obeys 6g, every day at every turn and obeys twice; 2. the Capsules of medicated powder being packed into, is obeyed 6, every day three times at every 0.3g at every turn.
Clinical trial
1.1 physical data
From year August in January, 2000 to 2009, accept hemorrhagic cerebral apoplexy patient totally 66 examples for medical treatment.All case is all made a definite diagnosis through multiple inspections such as health check-up and head CTs, and does not have liver, kidney, core function badness.Be divided into treatment at random and organize 33 examples, wherein: male 20 examples, women 13 examples, 28～70 years old age, average 47.5 years old; Matched group 33 examples, wherein male 19 examples, women 14 examples, 29～70 years old age, average 48.1 years old.Two groups are not all had significant difference (P＞0.05) at aspects such as sex, age, the state of an illness, have comparability, see table 1 for details.
Table 1 liang group case ordinary circumstance
Annotate: two groups relatively: P＞0.05
1.2 diagnostic criteria
1. the not smooth inducement of in love will, 2. confused suddenly servant, hemiplegia, mouthful eye
Tiltedly, dysphonia or lose consciousness servant, severe headache, dysphoria, dysphonia, companion's projectile vomiting suddenly, 3. red tongue with yellow fur, stringy and large pulse, 4. head CT shows: the intracranial hemorrhage focus is arranged.
1.3 Therapeutic Method
Matched group: adopt the routine of western medicine treatment, inhale O
2, the blood pressure regulation enalapril, control intracranial pressure 20% mannitol, prevention infection is selected antibiotic according to patient's the state of an illness and drug sensitive test, prevention stress ulcer losec, other takes symptomatic treatment.
Treatment group: add the embodiment of the invention 2 prescriptions on routine of western medicine treatment basis at matched group.Acute stage,, with being decocted in water for oral dose or nasal feeding: the flavor of 12 in embodiment 2 prescriptions Chinese medicine is put into marmite, and first fries in shallow oil and adds water 600ml and soaked 30 minutes, after boiling with high heat earlier, and 30 minutes at a simmer of reuse, the about 350ml of taking liquid; Second fries in shallow oil and adds water 500ml, boils earlier the back reuse with high heat 25 minutes at a simmer, the about 350ml of taking liquid; Two boil medicine liquid mix after clothes at twice, morning and evening service once, decoction being taken warmly or nasal feeding.
Recovery Phase of diseases: will 12 in embodiment 2 prescriptions flavor Chinese medicine pulverize the back and cross 100 orders or 120 mesh sieves, make superfine medicated powder after: 1. medicated powder and honey are made honeyed pill by 1: 1.5 weight ratio, every ball 3g obeys 6g, every day at every turn and obeys twice; 2. the Capsules of medicated powder being packed into, is obeyed 6, every day three times at every 0.3g at every turn.
Two groups treat 20 days respectively after, all carry out the head CT inspection before and after two groups of treatments, observe intracranial hematoma absorbing state and clinical symptoms improvement situation.
1.3 therapeutic evaluation
1.3.1 produce effects: consciousness is clear, limb functional recover, smooth running, clear, mouthful eye of language
Tiltedly recover; Head CT shows: absorption of hematoma is complete.
1.3.2 effectively: clinical symptoms improvement rate and head CT are observed the intracranial hematoma absorbance more than 70%.
1.3.3 take a turn for the better: clinical card shape improvement rate and head CT are observed the intracranial hematoma absorbance more than 50%.
1.3.4 invalid: clinical symptoms does not have obvious improvement rate and head CT is observed the intracranial hematoma absorbance less than 50%.
1.4 statistical method
Data are represented with rate, adopt X
2Check is that difference has statistical significance with P＜0.05.
1.5 result
1.5.1 two groups of doing well,improving situations relatively before and after the treatment
The treatment group adds Chinese medicine composition clinical symptoms improvement rate of the present invention (85%) at matched group on routine of western medicine treatment basis and obviously is better than matched group merely with routine of western medicine treatment back clinical symptoms improvement rate (53%), sees table 2 for details.
The table 2 liang forward and backward clinical symptoms of group treatment is improved routine number and improvement rate
Annotate: improvements=produce effects+effectively+improvement, below roughly the same.
1.5.2 the two groups of head CTs in treatment front and back observe the intracranial hematoma absorbance and the improvement rate compares
The treatment group adds at matched group that intracranial hematoma absorbance (90%) significantly is better than matched group merely with the intracranial hematoma absorbance (69%) after the routine of western medicine treatment behind the Chinese medicine composition of the present invention on routine of western medicine treatment basis, sees table 3 for details.
Head CT shows that the absorption of hematoma effect relatively reaches the improvement rate before and after the table 3 liang group treatment
1.5.3 untoward reaction
Matched group has 4 examples stress ulcer hemorrhage to occur, has 3 examples hematuria to occur, has 2 examples lower limb vein thrombus to occur; The treatment group is not seen thrombosis, does not also have other untoward reaction.
Model case
Case 1
Wei so-and-so, man, 40 years old, cadre, be Si Zhuan township Guo Xu Cun people, come the inventor to locate to go to a doctor on July 16th, 2004 with " hemorrhagic cerebral apoplexy (ventricular hemorrhage) ", in family numbers of patients generation, told 4 o'clock yesterday afternoons, because of feelings will not smooth, and dizzy suddenly, headache, once in the locality treatment, the commentaries on classics of not getting better.About 11 of evenings, left limb numbness, paralysis appear, slurred speech, mouthful eye suddenly
Tiltedly, confusion, for asking further treatment, the emergency inventor locates to go to a doctor.Looking into head CT shows: ventricular hemorrhage, the about 20～30ml of amount.Have a medical check-up: dizzy headache, left limb paralysis, numbness, slurred speech, mouthful eye
Tiltedly, flushing rough, red tongue with yellow fur, stringy and large pulse, blood pressure 180/100mmhg, heart rate 80 times/minute is breathed 37.5 ℃ of 20 times/minute, body temperature.
Determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs: the patient hinders strongly fragrant fire-transformation because of feelings will and causes liver-yang and rise suddenly and sharply, and QI and blood is disorderly contrary, on disturb key hyperamization clearly overflow the brain arteries and veins and dizziness, headache appear, quadriplegia, numbness, slurred speech, mouthful eye appear in side partially
Tiltedly, flushing rough, red tongue with yellow fur, stringy and large pulse, be resembling of depressed liver and heat transmission.
Tcm diagnosis: hemorrhagic cerebral apoplexy (liver-yang rises suddenly and sharply, blood oozing from the body openings or subcuta neous tissue brain arteries and veins), doctor trained in Western medicine is referred to as " cerebral hemorrhage ".
The rule of treatment: suppressing the hyperactive liver and subsiding YANG, hemostasia and dissipation blood stasis.
Side's medicine: the embodiment of the invention 2 prescriptions, preparation and using method.
Western medicine: the blood pressure regulation enalapril, control intracranial pressure 20% mannitol, prevention infection is selected antibiotic according to patient's the state of an illness and drug sensitive test, prevention stress ulcer losec, other takes symptomatic treatment.
After treatment 20 days, patient's dizziness, headache fade away, and left side paralyzed limbs function returns to the energy walking states gradually, lamprophonia, mouthful eye
Tiltedly recover normal, controlling of blood pressure is about 120/70mmhg, and head CT shows: this absorption of intracranial hematoma hexyl reaches the clinical cure standard.So far there is not recurrence through repeatedly following up a case by regular visits to.
Case 2
Pan so-and-so, the woman, 68 years old, the peasant was Li Gu people from village, Si Zhuan township, came the inventor to locate to go to a doctor 10 o'clock on the 18th February in 2000 with " hemorrhagic cerebral apoplexy (subarachnoid hemorrhage) ".Family numbers of patients is not smooth because of feelings will for telling before 20 days, and occur severe headache suddenly, fall forward dusk, a day symptom does not have obvious improvement surplus suddenly treating about 20 to county people's hospital, locate and change the inventor over to, disease is seen: severe headache, stiffness of the neck, dysphoria, confusion, slurred speech, companion's vomiting, red tongue with yellow fur stringy pulse.Head CT shows subarachnoid hemorrhage, blood pressure 170/95mmhg, pulse: 84 times/minute, breathe 37 ℃ of body temperature 20 times/minute.
Determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs: the patient is not smooth because of feelings will, strongly fragrant and fire-transformation, cause that liver-yang rises suddenly and sharply, the QI and blood superinverse, hold under the arm and cover clear key on the phlegm-fire, thus occur suddenly severe headache, dysphoria, base to dusk servant, slurred speech, red tongue with yellow fur stringy pulse, be the event of the interior amenorrhea network of heresy of wind-fire and phlegm-heat.
Diagnosis: hemorrhagic cerebral apoplexy (liver-yang rises suddenly and sharply, blood oozing from the body openings or subcuta neous tissue brain arteries and veins), doctor trained in Western medicine is referred to as subarachnoid hemorrhage.
The rule of treatment: suppressing the hyperactive liver and subsiding YANG, hemostasia and dissipation blood stasis.
Side's medicine: the embodiment of the invention 2 prescriptions, preparation and using method.
Western medicine: three weeks of absolute bed rest are raised 15 degree to head, blood pressure regulation enalapril, control intracranial pressure 20% mannitol, prophylactic use calcium-channel antagonists nimodipine, all the other symptomatic treatments.
The back patient has a headache and to fade away around treatment, realizes clearly, and the lamprophonia head CT shows: intracranial hemorrhage kitchen range basic absorption, controlling of blood pressure reach the clinical cure standard about 120/75mmhg.Through repeatedly following up a case by regular visits to so far not recurrence.
Claims (3)
1. the Chinese medicine composition of an auxiliary treatment hemorrhagic cerebral apoplexy is characterized in that described Chinese medicine made by each crude drug of following portions by weight:
3～10 parts of Radix Notoginseng, 3～10 parts of Pollen Typhaes, 3～10 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 3～6 parts of Crinis Carbonisatus, 2～5 parts of Scorpios, 3～10 parts in Rhizoma Gastrodiae, 10～15 parts of Ramulus Uncariae Cum Uncis, 15～20 parts of Concha Haliotidis, 10～15 parts of Flos Chrysanthemis, 1～3 part of Cornu Saigae Tataricae, 1.5～6 parts of Arisaema Cum Bile, 10～15 parts of Semen Plantaginiss.
2. the Chinese medicine composition of auxiliary treatment hemorrhagic cerebral apoplexy as claimed in claim 1 is characterized in that the parts by weight of described each crude drug are:
10 parts of Radix Notoginseng, 10 parts of Pollen Typhaes, 10 parts of Pseudobulbus Bletillae (Rhizoma Bletillae), 6 parts of Crinis Carbonisatus, 5 parts of Scorpios, 10 parts in Rhizoma Gastrodiae, 10 parts of Ramulus Uncariae Cum Uncis, 15 parts of Concha Haliotidis, 10 parts of Flos Chrysanthemis, 1.5 parts of Cornu Saigae Tataricae, 3 parts of Arisaema Cum Bile, 15 parts of Semen Plantaginiss.
3. the Chinese medicine composition of auxiliary treatment hemorrhagic cerebral apoplexy as claimed in claim 1 or 2 is characterized in that: the dosage form of described Chinese medicine composition is decoct, pill or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102275205A CN101716286B (en) | 2009-12-17 | 2009-12-17 | Traditional Chinese medicine composition for treating hemorrhagic stroke |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102275205A CN101716286B (en) | 2009-12-17 | 2009-12-17 | Traditional Chinese medicine composition for treating hemorrhagic stroke |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101716286A CN101716286A (en) | 2010-06-02 |
| CN101716286B true CN101716286B (en) | 2011-10-05 |
Family
ID=42430983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102275205A Expired - Fee Related CN101716286B (en) | 2009-12-17 | 2009-12-17 | Traditional Chinese medicine composition for treating hemorrhagic stroke |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101716286B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1377677A (en) * | 2002-03-18 | 2002-11-06 | 刘鑫隆 | Chinese patented medicine for curing cardio-vascular and cerebrovascular diseases and its preparing method |
| CN1806835A (en) * | 2005-01-18 | 2006-07-26 | 北京天泰源医药技术开发有限公司 | Pharmaceutical composition for treating cerebral hemorrhage and its preparation method |
-
2009
- 2009-12-17 CN CN2009102275205A patent/CN101716286B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1377677A (en) * | 2002-03-18 | 2002-11-06 | 刘鑫隆 | Chinese patented medicine for curing cardio-vascular and cerebrovascular diseases and its preparing method |
| CN1806835A (en) * | 2005-01-18 | 2006-07-26 | 北京天泰源医药技术开发有限公司 | Pharmaceutical composition for treating cerebral hemorrhage and its preparation method |
Non-Patent Citations (3)
| Title |
|---|
| 张春燕等.急性出血性中风的中医药治疗进展.《甘肃中医学院学报》.1999,第16卷(第1期),51-53. * |
| 张觉人等.中风辨治的现代思考.《辽宁中医杂志》.2005,第32卷(第9期),907-908. * |
| 樊永平等.中医药治疗出血性中风研究进展.《北京中医》.2005,第24卷(第2期),121-124. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101716286A (en) | 2010-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101342356B (en) | Traditional Chinese medicine preparation for congestion retardarce, haemal tube obstruction and preparation method thereof | |
| CN102698222A (en) | Drug for treating bradycardia and preparation method of drug | |
| CN106668607A (en) | Traditional Chinese medicine for treating gout | |
| CN103182012A (en) | Medicine for treating ischemic cerebral apoplexy and preparation method thereof | |
| CN101229345B (en) | Qi-replenishing and blood-enriching medicine | |
| CN103463467B (en) | A kind of seedling prescription wine with nourishing kidney yin | |
| CN102198181B (en) | Antithrombotic and thrombosis-eliminating preparation | |
| CN102188670B (en) | Medicament for treating extrauterine pregnancy | |
| CN101450189B (en) | Medicine for curing angiocardiopathy and cerebrovascular disease and its preparing method | |
| CN101716286B (en) | Traditional Chinese medicine composition for treating hemorrhagic stroke | |
| CN106938048A (en) | A kind of Chinese medicine preparation for treating cardiovascular and cerebrovascular disease | |
| CN105833055A (en) | Traditional Chinese medicine composition for treating hypertension, hyperlipidemia and hyperglycemia and preparing method and application thereof | |
| CN102579688B (en) | Blood pressure reducing chrysanthemum and dogbane leaf traditional Chinese medicine preparation | |
| CN111166849A (en) | Medicated bath composition for removing fatigue and improving sleep | |
| CN101129797B (en) | Medicine for treating closure type exogenous injury and internal damage and method of producing the same | |
| CN104605051A (en) | Double hemp-folium cortex eucommiae tea and preparing method thereof | |
| CN109771567A (en) | A kind of formula of Chinese herbal medicine supporting vital QI and dispersing blood stasis toxin expelling tumour | |
| CN103239626A (en) | Medicament formula for healthcare and treatment of middle-aged and elderly people | |
| CN103830495A (en) | Traditional Chinese medicine composition for treating fundus hemorrhage caused by diabetic retinopathy and preparation method thereof | |
| CN102614459B (en) | Traditional Chinese medicine spray for rapidly curing myocardial ischemia and preparation method thereof | |
| CN103099896A (en) | Herb tea for treating cardiovascular and cerebrovascular diseases | |
| CN102614461A (en) | Spray for rapidly relieving stenocardia and preparation method thereof | |
| CN102895352B (en) | Pharmaceutical composition and application thereof | |
| CN107617064A (en) | A kind of Chinese medicine preparation for treating menopausal syndrome and preparation method thereof | |
| CN105233075A (en) | Traditional Chinese medicine combination treating coronary heart disease |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20111005 Termination date: 20141217 |
|
| EXPY | Termination of patent right or utility model |