CN102698222A - Drug for treating bradycardia and preparation method of drug - Google Patents

Abstract

The invention discloses a drug for treating bradycardia and a preparation method of the drug, and belongs to difficult diesase category in the field of traditional Chinese medicine. The drug is characterized by comprising 17 drugs including prepared lateral radix of aconite, red ginseng, pseudo-ginseng and the like. The drug is prepared into the dosage forms such as troche, water-bindered pill and oral liquid. Bradycardia belongs to a disease form in western medicine arrhythmia, and Chinese medicine believes that pathogenesis of bradycardia is life-gate fire deficiency, heart-kidney yang (Chinese character) deficiency as causes and qi (Chinese character) stagnation, blood stasis and phlegm stagnates as symptoms; the bradycardia is a stubborn disease with asthenia in origin and asthenia in superficiality and mixture of asthenia and sthenia; the clinical features are: cardiopalmus, palpitation, precordial discomfort, weak chest pant, fatigue and force shortage, dizzy giddy, epigastralgia, pale tongue, white and thick or greasy coated tongue, fine and uneven pulse, oppressed breadth and mind or stabbing pain on a severe patient, dull pain, brachypnea, heart rate at about 40 per minute, suppressed waking in sleeping, frequent die feeling, surprise terror and emotional stress, and medical doctors advocate to providing a pacemaker as to these situations. The drug disclosed by the invention is a product by 20 years of clinical research practices, and over 80 critical patients who refuse to be installed with the pacemaker are cured. The drug has stable curative effect without adding any western medicine preparation, and no pure traditional Chinese medicine preparation similar with the drug disclosed by the invention is found out according to the existing data at present.

Description

Bradycardic medicine of a kind of treatment and preparation method thereof

One, technical field:

The present invention is bradycardic medicine of a kind of treatment and preparation method thereof, belongs to tcm field difficult disease category.

Two, background technology:

1, bradycardia is ARR a kind of pathological changes, is because of heart collecting moving arhythmicity, and under normal circumstances, the impulsion of heartbeat originates from sinuatrial node, its rhythm and pace of moving things rule, and heart rate is in 60-100 time/minute scope; Impulsion propagates into two atrium earlier, passes through normal propagation approach in atrioventricular node and the ventricle then, spreads two ventricles with certain speed, is called normal sinus rhythm.All cardiomotilitys that departs from this normal cardiac rhythm all belong to arrhythmia; Common have sinus bradycardia, early rich, paroxysmal tachycardia, atrioventricular block, sinuatrial node conduction block, a preexcitation syndrome etc.; Even not serious when primary disease begins, also possibly develop into serious arrhythmia, so very important.

ARR major lesions is at the heart, but with other internal organs substantial connection arranged because Chinese medicine think human body be one unified whole.Heart master blood house mind, main gods, the motive promote heart collecting moving under the synergism of lung qi, and with the blood transport whole body, each internal organs normal function of nutrition is movable.Taste are reservoir of food and drink, biochemical former of QI and blood, main in gas, ascending the clear and descending the turbid is drawn essence of water and grainization and is given birth to nutrient blood and support whole body, so title " the foundation of acquired constitution ".Kidney storing essence master water, main bone is given birth to marrow, and brain being the marrow sea is the house of mental activity, relies on painstaking effort, and the keeping of kidney essense is dominated thinking, the spirit and consciousness function; The kidney being a ZANG-organ containing both water and fire, the built-in gate of vitality is kidney-yang, and promptly kidney yang is some vigour that inherent father and mother give, so claim Yuanyang again.Yuanyang is that promotionization is given birth to vital organs of the human body functional activities, and qiactivity of triple energizer is movable, and the motive power of human body growth promoter, reproductive function, so the title kidney is " the congenital foundation ".The kidney-yang temperature of the gate of vitality is smoked the taste digesting food, draw precise and tiny, under the effect of heart-yang extracting juice change and red be Weihe blood, annotate nutrition whole body in arteries and veins, five-elements theory is called " fire generating earth ".The gate of vitality is kidney-yang (kidney yang) is each internal organs sun the dominator of QI, in the human life activity, occupy an leading position, and as there is the sun in universe, be the origin of all things on earth growth especially.Heart kidney belongs to shaoyin channel together, and meridians link to each other, and QI and blood communicates, and heartbeat is unable, slow, arrhythmia so flaccidity of the heart-yang occurs, and necessary temperature compensation kidney life is kidney-yang to subsidize heart-yang, just can keep normal physiological function.Blood stored in the liver, main catharsis, body is cloudy and with sun, dominant force feelings will is considered, and the catharsis function of liver directly has influence on the functional activity of heart.So ARR pathological changes, inseparable relation is arranged with vital organs of the human body normal physiological function.

3, the modal cause of disease has: the one, and evil poison invasion, the interior house in the heart, the consumption impairment of QI is cloudy, and heart arteries and veins loses supports and proarrhythmia.The 2nd, direct stimulation, seven emotions discord, qi depression to blood stasis, heart arteries and veins are obstructed conduction abnormalities.The 3rd, decline of the fire from the gate of life, deficiency of heart-QI, flaccidity of the heart-yang, heartbeat is unable, and blood is not sought network, and arteries and veins gas can not normally be failed cloth.The 4th, QI and blood deficiency, imbalance of YIN and YANG and to cause arteries and veins rule not normal.To sum up state: the primary disease cause of disease has exopathogen, internal injury not, the dialectical branch that deficiency and excess is arranged, and empty more than reality, normal deficiency complicated with excess, or transform each other; Further develop normal " fainting ", " taking off " critical signs such as (being angina pectoris, myocardial infarction, sudden cardiac arrest, sudden death) that occurs like the state of an illness.

4, the present invention is only to ARR bradycardia type research treatment.Bradycardia belongs to traditional Chinese medical science insufficiency of heart-QI, flaccidity of the heart-yang pattern of syndrome, and its clinical manifestation is: cardiopalmus, palpitation with a distress feeling, pareordia discomfort, sensation of oppression over the chest with shortness of breath, spiritlessness and weakness, dizziness, aversion to cold and cold limbs, pale tongue, white fat or white being bored with of tongue, and tongue side tooth seal, deep-thready pulse is irregular; Feel oppressed in severe patient ambition or twinge, dull pain, cannot not breathe hard continuously, heart rate about 40 times/minute, and uneasy sleeping at night, frightened cautious is suppressed awakely in sleeping, dead frequently sense is arranged, and is nervous, pale complexion, inappetence, vomiting and nausea or diarrhoea, dizzy desire are fallen forward, and tired unable, speech does not have god.The common sinus bradycardia of Electrocardioscopy, arrhythmia, conduction block, myocardial ischemia often is diagnosed as coronary heart disease, nervus cardiacus functional disease etc., normal acardia organic disease.The heart rate per minute is lower than the person 50 times, and doctor trained in Western medicine advocates to settle pacemaker.

5, differential diagnosis in tcm is thought: bradycardic etiology and pathogenesis is that decline of the fire from the gate of life, deficiency of heart-YANG and kidney-YANG, hypoactivity of spleen-YANG are this, and the stagnation of QI, blood stasis, the turbid strongly fragrant resistance of expectorant are mark, belong to the card of deficiency in origin and excess in superficiality." element ask vital QI of the body connecting with natural QI opinion " cloud: " heart person, root of life, god's change also, its China is at face, it fills at blood vessels, is yang meridians of hands, leads in summer-QI." heart kidney belongs to shaoyin channel together, and is clear. Zheng Qinan " doctor's method is flexible " roll up four clouds: " few the moon is the ground of combination of essence and spirit order, the root of vigour, the master of personal life also, sick is the vigour fictitious pole to hereat, shell as for root, this point vigour clear clear under, cover the world ".Cloud again: " why the madam gives birth to and the dead not, only relies this more congenital vital qi ear, and vital qi was on 1st, and the people promptly lived one, and vital qi is died at once, and the people also dies at once, so say: people's one breath of living, gas both sun also, fire also, non-this fire of people is living.”

6, as far back as early seventies; I is the just normal zhigancao decoction of using treatise on Febrile Diseases in facing card; " Medical Treasures of the Golden Chamber " draw together the Bulbus Allii Macrostemonis Chinese liquor soup that withers, draw together the side's sanctions such as Bulbus Allii Macrostemonis Rhizoma Pinelliae soup, zhishi xiebai guizhi decoction of withering and treat ARR various disease, obtain curative effect preferably.Recognized progressively since the eighties that bradycardia disease shows one deficiency of spleen-YANG and kidneyYANG, flaccidity of the heart-yang, the deficiency-cold syndrome of decline of the fire from the gate of life resembles, and excess caused by deficiency and the difficult state of an illness of deficiency syndrome mingling with excess syndrome such as the stagnation of QI, blood stasis, expectorant be turbid occurs.According to these understanding; With reference to forefathers' experience, work out treatment bradycardia prescription evident in efficacy finally, in more than 20 years face confirms to trample, constantly sum up and improve and become the present invention; And successfully cure and confirm as bradycardia through doctor trained in Western medicine and be reluctant example surplus the device pacemaker patient 80; Heart rate was brought up to more than 60-78 time/minute, and efficacy consolidation, did not add to use any Western medicine prepn.

The present invention is the crystallization of clinical research over more than 20 year, practice, does not find and the similar pure Chinese medicinal preparation of the present invention as yet according to the available data retrieval.

7, typical case: " myasthenia gravis, bradycardia case "

Open XX, the man, 38 years old, the truck driver, fat; The conscious whole body weakness of getting up morning in July, 2011, tired the breathing hard of the action heart panted, and thinks that hunger causes, do not feel any better the driving of getting on the bus reluctantly after speed is had breakfast; Unexpectedly the unable clutch of stepping on down of foot, squat down and separate just or sits ground, entirely so unable standing in the unable gearshift of hands position; Needing others firmly to pull can stand, and once privy has been separated greatly after an action of the bowels in the building site, unable standing, unmanned again help; Squat double-legged numbness, the aching and limp ground of kneeling, having no time to attend to ground, lavatory dung urine mud drenches, dirty smelly dirty, how far creeps 1m to last pouncing on; Both hands are caught a timber of building the lavatory, and the power of using up sucking is just being struggled and stood up, and unable walking in more than 10 minute is happened the workman that goes to toilet it is assisted in, bathing, changes one's clothes, has a rest ... Sobbing with grief endlessly of speech.The anxious West China hospital that send was in hospital in the 3rd day, was diagnosed as on inspection: multiple diseases such as " myasthenia gravis, bradycardia, hearts rate 40 times/minute; the conduction block of the right bundle branch of companion, arrhythmia, hypotension, fatty liver; abnormal liver function ", and be responsible for the doctor and accuse it, must the device pacemaker.The hospitalization commentaries on classics of not getting better after more than 20 day, financial resources are most, in moving home, ask my diagnosis and treatment upon somebody's introduction, and it is pale simple and unadorned to examine the meeting color; Heart rate 40 times/minute, heartbeat is unable, arrhythmia, uncomfortable in chest, the heart is tired breathes hard deep-slow pulse; Blood pressure 70/50mm mercury column, pale tongue, tongue is greasy in vain, food difference loose stool, from apogee sweating, the whole body weakness; Walking need to be helped, both feet limpings that mop floor, and sitting down and standing all needs the people to pull, and the state of an illness is complicated and seriously.Examine to ordering fire according to arteries and veins card on the decline, deficiency of spleen-YANG and kidneyYANG, flaccidity of the heart-yang, cold and damp stagnation, venation is not smooth.Though disease complicacy and old complaint is identical, the our heavy dose of decoction of urgent need, potion on the one.Further consultation after 7 days, heart rate 58 times/minute, myasthenia is improved, and rises and sits the help of not chosen, and appetite, diarrhoea take a turn for the better, blood pressure 90/70mm mercury column, the state of an illness takes a favorable turn; The continuous plus-minus with we recuperated under medical treatment March, heart rate 78 times/minute, and blood pressure 120/80mm mercury column, electrocardiogram is normal, and whole body is strong, recovers driving work.

Three, summary of the invention:

1, the present invention is made up of following medicine and weight proportion thereof:

Radix Aconiti Lateralis Preparata 10-60 part Ramulus Cinnamomi 10-50 part Rhizoma Zingiberis 10-60 part Herba Ephedrae 10-40 part Herba Asari 6-20 part Radix Ginseng Rubra 10-50 part

Radix Astragali 20-100 part Rhizoma Atractylodis Macrocephalae 10-50 part Poria 10-50 part Fructus Amomi 10-30 part Radix Glycyrrhizae Preparata 10-50 part Radix Notoginseng 10-30 part

Radix Angelicae Sinensis 10-30 part Rhizoma Chuanxiong 10-30 part Radix Salviae Miltiorrhizae 10-40 part Lignum Santali Albi 10-30 part Rhizoma Acori Graminei 10-30 part

2, preferred weight proportioning of the present invention is:

Radix Aconiti Lateralis Preparata 20-60 part Ramulus Cinnamomi 15-50 part Rhizoma Zingiberis 15-40 part Herba Ephedrae 10-30 part Herba Asari 6-15 part Radix Ginseng Rubra 15-50 part

Radix Astragali 30-100 part Rhizoma Atractylodis Macrocephalae 15-50 part Poria 15-50 part Fructus Amomi 10-30 part Radix Glycyrrhizae Preparata 15-50 part Radix Notoginseng 10-30 part

Radix Angelicae Sinensis 15-30 part Rhizoma Chuanxiong 15-30 part Radix Salviae Miltiorrhizae 15-40 part Lignum Santali Albi 10-30 part Rhizoma Acori Graminei 10-30 part

3, optimum weight proportioning of the present invention is:

30 parts of 60 parts of Rhizoma Atractylodis Macrocephalaes of 30 parts of Radixs Astragali of 10 parts of Radix Ginseng Rubra of 20 parts of Herba Asaris of 30 portions of Herba Ephedraes of 30 portions of Rhizoma Zingiberiss of 50 parts of Ramulus Cinnamomi of Radix Aconiti Lateralis Preparata

15 parts in 30 portions of Lignum Santali Albis of 30 parts of Radix Salviae Miltiorrhizaes of 30 parts of Rhizoma Chuanxiongs of 15 parts of Radix Angelicae Sinensis of 30 portions of Radix Notoginseng of 20 parts of Radix Glycyrrhizae Preparatas of 30 parts of Fructus Amomis of Poria

15 parts of Rhizoma Acori Graminei

4, the nature and flavor of prescription drug of the present invention and effect:

Radix Aconiti Lateralis Preparata: hot, sweet, big heat, GUIXIN, kidney, spleen channel.The hot sweet big heat of these article is the dry strong article of pure sun, and the key medicine of recuperating depleted YANG and rescuing the patient from collapse is used for YANG asthenia disease, and it is contrary to faint like extremity, cold spontaneous sweating, the yang depletion syndrome of faint pulse being about to disappear.Help heart-yang to promote blood circulation on these article, middle warming the spleen sun is with cold expelling, and following kidney-replenishing is controlled insufficiency of kidney-YANG, decline of the fire from the gate of life with the benefit fire.This product eliminating cold to stop pain effect that also tool is stronger is usually used in wind-cold-dampness arthralgia.Gui: acrid, sweet, warm, lungs, heart, bladder, this product can Warming yang, to help guard the table sweating Jie Ji, but also warm meridians cold pain, through the yang qi, cure cold coagulation stagnation The arthralgia, moisture inside the stop of phlegm, edema, heart yang appetite, chest pain adverse blood, heart palpitations, pulse knot generation.Rhizoma Zingiberis: hot, hot, return spleen, stomach, the heart, lung meridian, the hot yang-energy that can help taste of these article is the key medicine of warming spleen and stomach for dispelling cold, and the kind hot logical heart is supporing yang, and recuperating depleted YANG is promoted blood circulation, every and Radix Aconiti Lateralis Preparata be with controlling yang depletion syndrome, again can warming the lung to resolve fluid-retention, control cold fluid-retention and lie prostrate breathing with cough of lung.Herba Ephedrae: suffering, little hardship, temperature is returned lung, urinary bladder channel, and these article and Radix Aconiti Lateralis Preparata, Herba Asari compatibility have the effect of dispersing wind-cold, warming the kidney to activate YANG, and ephedrine has excited heart, vasoconstrictive, rising blood pressure, the effect of excited maincenter.Herba Asari: suffering, temperature is returned lung, kidney, heart channel, and the hot perfume (or spice) of these article is walked to scurry, and about the exterior and the interior that has a thorough knowledge of, dispersing cold for relieving pain power wins, and rises a suffering and looses and logical all keys, can strengthen myocardial contraction, makes the heart rate quickening, the CF increase.Radix Ginseng Rubra: sweet, little hardship, tepor, GUIXIN, lung, spleen channel, these article merit is arrogated to oneself strongly invigorating primordial QI; Arise from kidney under the vigour, up in lung, be the source of human life power, decline so be used to save first deficiency of vital energy; Faint pulse being about to disappear take off disease, can invigorating the spleen to benefit the lung, spleen lung brio is blood Wang Jinsheng then, refreshing peace intelligence increases; Be used for cardiopalmus, the insomnia, forgetful of deficiency of qi and blood again, diseases such as malaise are treatment asthenia internal injury, and emergency treatment of collapse is held up the good medicine of danger.The Radix Astragali: sweet, tepor is returned lung, spleen channel, and these article are apt to the gas of spleen reinforcing lung, and the laudatory title of the length of QI invigorating is arranged, and is good at the elevate a turnable ladder yang-energy again; Be used for all diseases of deficiency of both the splenic and pulmonary QI, as the spleen sun do not rise, the hernia of sinking of QI of middle-JIAO, proctoptosis, visceroptosis person be particularly suitable, can defend consolidating superficial resistance in fact again, hidroschesis can qi-supplementing, blood-engendering, hemostasis by invigorating QI; Promote the production of body fluid, these article also have and protect the liver, and improve renal function, and diuresis promotes hemopoietic function, defying age; The antiviral tumor, blood vessel dilating, blood pressure lowering, heart tonifying, effects such as resisting myocardial ischemia.The Rhizoma Atractylodis Macrocephalae: hardship, sweet, temperature is returned spleen, stomach warp, and these article merit is arrogated to oneself QI invigorating, and the spleen strengthening and damp drying is the spleen invigorating key medicine, again can inducing diuresis to remove edema, control phlegm retention, the exterior deficiency spontaneous perspiration, inappetence is controlled pregnant frequent fetal movement.Poria: sweet, light, flat, GUIXIN, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen-benefiting mind-tranquilizing is kindly controlled various edema, and kind spleen invigorating mind calming, calms the nerves, and controls insufficiency of the spleen all diseases and palpitation and insomnia.Fructus Amomi: suffering, temperature is returned spleen, stomach warp, and the hot fragrant temperature of these article is loose, burnt turbid damp in the kind virtueization, stagnant gas in warming the spleen, the reason stomach has good warming spleen and stopping diarrhaly, and removing dampness is whetted the appetite, the antiabortive effect of regulating the flow of vital energy.Radix Glycyrrhizae Preparata: sweet, temperature is gone into the heart, lung, stomach warp, has the spleen reinforcing lung moistening; Detoxifcation, emergency, the coordinating the actions of various ingredients in a prescription effect is so be widely used; With the severe palpitation of controlling deficiency of heart-QI, irregularly intermittent and regularly intermittent pulse, the ability invigorating the heart and spleen is with multiple arteries and veins; Control the weakness of the spleen and stomach deficiency of QI in middle-JIAO, coordinating the actions of various ingredients in a prescription is cold, hot, toxicity, so the title of " state is old " is arranged.Radix Notoginseng: sweet, little hardship, temperature is returned liver, stomach warp, and these article can stop blooding and kind blood stasis dispelling, hemostasis is arranged and do not stay the stasis of blood, blood stasis dispelling not to hinder characteristics just, and drug effect is remarkable, is mass formed by blood stasis good medicine, is used for coronary heart disease, angina pectoris, apoplexy sequela, and satisfactory effect is all arranged.Radix Angelicae Sinensis: sweet, suffering, temperature is returned liver, the heart, spleen channel; The hot row of the sweet benefit of these article, the Wen Tongzhi profit, have good enrich blood, invigorate blood circulation, analgesic effect, its sweet in the mouth and weighing; So specially can enrich blood, its gas is light and hot, so again can promoting the circulation of blood, invigorating middle warmer has row, in the row benefit arranged; Be gas medicine in the blood, also panacea in the blood, all diseases of suitable blood part.Rhizoma Chuanxiong: hot, temperature, return liver, gallbladder, pericardium channel, the hot temperature of loosing of these article is led to, is walked and do not keep, and push up on up top, and the descending sea of blood, bypass extremity are the gas medicine in the blood, have good blood-activating and qi-promoting, and the effect of wind-expelling pain-stopping is to qi depression to blood stasis the most suitable that the cold coagulation person uses of holding concurrently.The ability coronary blood flow increasing reduces myocardial oxygen consumption, and microcirculation improvement reduces surface activity of blood platelet, effects such as anticoagulant, and antagonism thrombosis has remarkable preventive effect to ischemic cerebrovascular.The red sage root: bitter, be slightly cold, the thoughts of returning home, Liver Channel, this product bitter cold is fallen and is let out, and goes into conscience blood part, is key medicine promoting blood circulation and removing blood stasis, is widely used in various hemostasis diseases, and trusted subordinate's shouting pain is controlled in the disease eliminating powder junction pain relieving, and the also kind cool serum heart, relieving restlessness are calmed the nerves.Santal: hot, temperature, return taste, lung channel, the hot fragrant temperature of this product is logical, is longer than the smooth chest diaphragm mechanism of qi of a surname, cold, the pain relieving of loosing, appetizing.Rhizoma Acori Graminei: hot, bitter temperature, GUIXIN stomach warp, these article pungent drugs can disperse and bitter drugs can purge temperature is logical, fragrance is walked to scurry, merit is arrogated to oneself resuscitation inducing and mind tranquilizing, but the removing dampness of holding concurrently eliminate the phlegm, ward off dirtyly, ability key, damp eliminating happily is turbid, refreshment will.

5, the present invention separates the side of prescription:

According to bradycardic main etiology and pathogenesis is deficiency of heart-YANG and kidney-YANG, hypoactivity of spleen-YANG, and decline of the fire from the gate of life is this, qi depression to blood stasis, functional activity of QI being not smooth; The strongly fragrant resistance of turbid damp is mark, belongs to deficiency syndrome mingling with excess syndrome, and the disease of deficiency in origin and excess in superficiality is so the rule of treatment is when kidney-yang to mend the gate of vitality; Help the heart, the yang-energy of kidney, taste, replenishing vital QI with drugs of warm nature QI and blood are this, blood circulation promoting and blood stasis dispelling; Promoting of the circulation of QI and removing the obstruction in the collaterals, the removing dampness of cold expelling virtue is turbid, and unimpeded mechanism of qi is mark, giving consideration to both the incidental and fundamental.So it is monarch drug that we adopt Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Rhizoma Zingiberis, Herba Ephedrae, Herba Asari, complete that to mend the gate of vitality kidney-yang, go deep into the shaoyin channel arteries and veins, help the sun of heart kidney, increase the power of heartbeat, and improve heart rate; Adopting Radix Ginseng Rubra, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Fructus Amomi, Radix Glycyrrhizae Preparata is ministerial drug, the gas of big reinforcing the heart, lung, spleen channel, the strong fortune function of gas in helping, appetite stimulator, qi-supplementing, blood-engendering, the turbid phlegm stagnancy of removing dampness; Adopting Radix Notoginseng, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae is adjuvant drug, blood circulation promoting and blood stasis dispelling, and promoting of the circulation of QI and removing the obstruction in the collaterals, dispersing the stagnated live-QI to relieve the stagnation of QI, microcirculation improvement, myocardial ischemia, anoxia increase arteria coronaria and cardiac blood flow, thereby stronger raising heart rate are improved the rhythm of the heart; Adopting Lignum Santali Albi, Rhizoma Acori Graminei is messenger drug, and Xin Xiang walks to scurry, the smooth ambition of Wen Tongxuan mechanism of qi, the ambition pain of feeling oppressed is alleviated in the refreshment of having one's ideas straightened out, doubleization be turbid ward off dirty, the chest stuffiness relieving stomach function regulating.Full side's medication is superior, and compatibility is rigorous, monarch, minister, helps, makes and show what one's be, and plays the raising heart rate altogether, improves the rhythm of the heart, treats bradycardic effect.

Four, implementation method:

1, the various drug purifications of the present invention are handled, claimed sufficient deal by the optimum weight proportioning, splendid attire is subsequent use respectively.

2, the Radix Aconiti Lateralis Preparata coarse sand is stirred to the yellow foaming, the nothing of chewing fiber crops flavor purifies subsequent use.

3, various medicines are closed even, Exposure to Sunlight or drying room are dry, pulverize to be micropowders.

4, micropowders is added binding agent such as starch, compacting is system in flakes, the heavy 0.5g of sheet, sterilization, per 100 bottled, sealings.

5, micropowders is prepared into the watered pill, big like Semen Firmianae, sterilization, the bottled sealing of every 100g.

6, with the 3rd drying for standby medicine of implementation method broken be coarser powder, add 8 times of amounts of drinking water, soak 24h, whenever stir once at a distance from 8h.

7, will soak medicine and water behind the 24h, heated and boiled 1.5h, filters the extracting juice clarification at cooling.

8, will get antiperspirant after medicinal residues add 6 times of amounts of drinking water, boil 2h, cooling, filtration, extracting juice clarification.

9, two secondary clearing medicinal liquids are closed even, boil half h, filter, clarification, sterilization is prepared as oral liquid.

10, oral liquid is divided in vial or the non-toxic plastic bottle, every bottle of 20ml, sterilization, encapsulation are whenever closed five, are equipped with suction pipe.

11, dosage forms such as the tablet of medication preparation of the present invention, the watered pill, oral liquid are said dosage forms on any pharmaceutics.

Claims (10)

1. the present invention is made up of following medicine and weight proportion thereof:

Radix Aconiti Lateralis Preparata 10-60 part Ramulus Cinnamomi 10-50 part Rhizoma Zingiberis 10-60 part Herba Ephedrae 10-40 part Herba Asari 6-20 part Radix Ginseng Rubra 10-50 part

Radix Astragali 20-100 part Rhizoma Atractylodis Macrocephalae 10-50 part Poria 10-50 part Fructus Amomi 10-30 part Radix Glycyrrhizae Preparata 10-50 part Radix Notoginseng 10-30 part

Radix Angelicae Sinensis 10-30 part Rhizoma Chuanxiong 10-30 part Radix Salviae Miltiorrhizae 10-40 part Lignum Santali Albi 10-30 part Rhizoma Acori Graminei 10-30 part

2. preferred weight proportioning of the present invention is:

Radix Aconiti Lateralis Preparata 20-60 part Ramulus Cinnamomi 15-50 part Rhizoma Zingiberis 15-40 part Herba Ephedrae 10-30 part Herba Asari 6-15 part Radix Ginseng Rubra 15-50 part

Radix Astragali 30-100 part Rhizoma Atractylodis Macrocephalae 15-50 part Poria 15-50 part Fructus Amomi 10-30 part Radix Glycyrrhizae Preparata 15-50 part Radix Notoginseng 10-30 part

Radix Angelicae Sinensis 15-30 part Rhizoma Chuanxiong 15-30 part Radix Salviae Miltiorrhizae 15-40 part Lignum Santali Albi 10-30 part Rhizoma Acori Graminei 10-30 part

3. optimum weight proportioning of the present invention is:

30 parts of 60 parts of Rhizoma Atractylodis Macrocephalaes of 30 parts of Radixs Astragali of 10 parts of Radix Ginseng Rubra of 20 parts of Herba Asaris of 30 portions of Herba Ephedraes of 30 portions of Rhizoma Zingiberiss of 50 parts of Ramulus Cinnamomi of Radix Aconiti Lateralis Preparata

15 parts in 30 portions of Lignum Santali Albis of 30 parts of Radix Salviae Miltiorrhizaes of 30 parts of Rhizoma Chuanxiongs of 15 parts of Radix Angelicae Sinensis of 30 portions of Radix Notoginseng of 20 parts of Radix Glycyrrhizae Preparatas of 30 parts of Fructus Amomis of Poria

15 parts of Rhizoma Acori Graminei

4. the various drug purifications of the present invention are handled, claimed sufficient deal by the optimum weight proportioning, splendid attire is subsequent use respectively.

5. the Radix Aconiti Lateralis Preparata coarse sand is stirred to the yellow foaming, the nothing of chewing fiber crops flavor purifies subsequent use.

6. various medicines are closed evenly, Exposure to Sunlight or drying room are dry, pulverize to be micropowders.

7. micropowders is added binding agents such as starch, compacting is system in flakes, the heavy 0.5g of sheet, sterilization, per 100 bottled, sealings.

8. micropowders is prepared into the watered pill, big like Semen Firmianae, sterilization, the bottled sealing of every 100g.

With the 3rd drying for standby medicine of implementation method broken be coarser powder, add 8 times of amounts of drinking water, soak 24h, with the medicine and the water that soak behind the 24h, heated and boiled 1.5h; Cooling, the clarification of filtration extracting juice add 6 times of amounts of water with medicinal residues again, boil 2h, and cooling, filtration, extracting juice clarification are closed two secondary clearing medicinal liquids even then; Boil half h, filter, clarify, sterilization is prepared as oral liquid, and oral liquid is divided in vial or the non-toxic plastic bottle; Every bottle of 20ml, sterilization, encapsulation are whenever closed five, are equipped with suction pipe.

10. dosage forms such as the tablet of medication preparation of the present invention, the watered pill, oral liquid are said dosage forms on any pharmaceutics, the prescription protection.