CN101711528B - Compound medicinal composition for destroying and expelling rotifers and protozoa and preparation method thereof - Google Patents
Compound medicinal composition for destroying and expelling rotifers and protozoa and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a compound medicinal composition for destroying and expelling rotifers and protozoa and a preparation method thereof, which belong to the field of veterinary medicament. The compound medicinal composition comprises rhizome zingiberis, stone-like omphalia, areca-nut, common carpesium fruit, male fern rhizome, the tuber of stemona, kuh-seng and anhydrous cupric sulfate. The compound medicinal composition of the invention can effectively control fulminant rotifers and protozoa diseases in culture ponds of fishes, shrimps and crabs, and particularly can avoid the shrimps and the crabs hypoxia caused by the fulminant rotifers and protozoa diseases in the culture ponds of the shrimps and the crabs; and at the same time, the compound medicinal composition can kill the protozoa such as chilodonella, the rotifers and the like and the resting eggs of the rotifers. The compound medicinal composition is green, safe and environmentally-friendly, and has no toxic or side effect on the shrimps and the crabs; the compound medicinal composition does not generate medicament residue harm to human health and medicament resistance, and does not pollute the environment; and in the compound medicinal composition, 95 percent of medicament grain has the diameter of 50 microns, the effective component of the medicament can be released quickly, the medicament dosage can be reduced, the medicament resource is saved, and the cost is reduced.
Description
Technical field
The present invention relates to a kind of wheel animalcule and protozoic compound medicament composition and preparation method thereof killed, belong to field of veterinary.
Background technology
The former chamber of wheel Eimeria animal trolley Piroplasmea, build is small, is the important component part of water body zooplankton.In fish pond, sewage pond, the wheel animalcule biomass often accounts for the first place in zooplankton biomass.In fish production, wheel animalcule is a kind of good animality natural bait, and most fries are from endogenous nutrition to the exogenous nutrition transformation stage, and wheel animalcule is the most agreeable to the taste high-quality bait.
Yet in recent years along with aquaculture scale, breeding density constantly increase, for pursuing higher cultured output, increase economic efficiency, raiser's high-quality manufactured feed of throwing something and feeding in a large number causes the breeding water body load increasing, and breeding environment obviously worsens.Especially at northern area, water resources shortage, breeding water body use the old water in pond or do the water source with the sanitary sewage after the self-purification, and mud is thicker, chip is more, be very easy to cause the pond waters eutrophication, for wheel animalcule, protozoic excessive multiplication have been created suitable condition.In case breeding water body wheel animalcule amount reproduction, a large amount of phytoplanktons such as algae in the water body of can ingesting cause water hypoxia, cause fish, shrimp to raise the nose above water to breathe and even general pond; Some wheel animalcule also can large quantities ofly be bonded to the shrimp body, makes shrimp body thorax appendage body become sepia or brown-black generation ulcer symptom, causes prawn appetite to subtract greatly, moves about slow, and serious also can cause the culture shrimp crab dead in batch, causes serious economic loss to the raiser.
The general Symptoms of breeding water body fulminant wheel animalcule disease is, breeding water body becomes shallow khaki by blue-green suddenly, the fish intensity of feeding obviously weakens, fish very easily occurs and raises the nose above water to breathe or general pond in the time-division close to daybreak, one deck oil film shape covering is arranged in the cultivating pool leeward, observing water body adularescent point with transparent bottle moves about, microscopy is viewed as a large amount of wheel animalcule corpse and the new small-sized wheel animalcule of breeding (being mainly gyalectiform Brachionus, crystal sac Brachionus, three limb wheel animalcules, many limbs wheel animalcule etc.) etc., also has simultaneously the protozoas such as a lot of film mouth worms, trip servant worm, oblique tube insect.
At present, generation for control breeding water body fulminant wheel animalcule and protozoa disease, the raiser adopts chemicals or pesticide insecticidal materials full pool spilling head method to kill wheel animalcule etc. mostly, can play preferably killing effect at short notice, but because the toxic and side effect of these medicines own is larger, the culture shrimp crab there is larger injury, the careless slightly mortality that will cause the culture shrimp crab; In addition, this type of medicine is limited to the Resting Eggs of Rotifers In The Water killing action, and wheel animalcule often can be caused disease by amount reproduction again a period of time after the medication.So what the raiser need to find a kind of highly effective and safe in a hurry kills wheel animalcule and protozoic medicine.
Summary of the invention
The object of the present invention is to provide a kind of green, safety, environmental protection, kill wheel animalcule and protozoic compound medicament composition efficiently, be applicable to shrimp crab culturing pool by water hypoxia and the general pool that fulminant wheel animalcule disease causes, simultaneously the protozoa such as oblique tube insect, Trichodina and Resting Eggs of Rotifers In The Water in the water body had killing action.This compound medicament composition adds chemicals copper sulphate on the basis of Chinese herbal medicine, can not only play quick killing action to the wheel animalcule in the water body and protozoa, and can keep lastingly water body Chinese traditional medicine concentration, play and continue thoroughly to kill wheel animalcule and protozoic effect in the water body.In addition, the present invention is by using superfine communication technique, break the Chinese herbal medicine cell wall and the granularity that obtains less than 50 microns impalpable powder, powder diameter is little, be evenly distributed, the quality homogeneous, be conducive to the release of effective ingredient, reduce dosage, save medicinal material, reduce cost.This pharmaceutical composition safe range is large, the situation of having avoided using the pest control with insecticide medicine easily to cause cultivating fish, shrimp, the crab casualties occurs, have no side effect by the recommended dose use, higher to culture shrimp, crab, fish safe concentration, can not damage and water body pollutes the cultivation object, can not produce harm humans health medicament residue, free from environmental pollution, can not cause drug induced disease.
Another object of the present invention is to provide the preparation method of this compound medicament composition.
The objective of the invention is to be achieved through the following technical solutions:
The invention provides a kind of wheel animalcule and protozoic compound medicament composition killed, it comprises the raw material of following weight proportioning: 1-40 parts of rhizoma zingiberis, 1-60 parts of stone-like omphalias, 1-60 parts of betel nuts, 1-60 parts of Lappula echinatas, 1-100 parts of thick wood-fern rhizomes, 1-60 parts of the tubers of stemona, 1-60 parts of kuh-sengs, 1-200 parts of anhydrous cupric sulfates.
Further, the raw material weight proportioning of described compound medicament composition is: 5-30 parts of rhizoma zingiberis, 10-50 parts of stone-like omphalias, 10-50 parts of betel nuts, 10-50 parts of Lappula echinatas, 20-80 parts of thick wood-fern rhizomes, 10-50 parts of the tubers of stemona, 10-50 parts of kuh-sengs, 20-150 parts of anhydrous cupric sulfates.
Further, the raw material weight proportioning of described compound medicament composition is: 10-20 parts of rhizoma zingiberis, 15-40 parts of stone-like omphalias, 15-40 parts of betel nuts, 15-40 parts of Lappula echinatas, 30-70 parts of thick wood-fern rhizomes, 15-40 parts of the tubers of stemona, 15-40 parts of kuh-sengs, 40-120 parts of anhydrous cupric sulfates.
Of the present inventionly kill wheel animalcule and protozoic compound medicament composition can be other formulation, the preferred powder of the present invention.
For better and fully play the drug effect of this compound medicament composition, diameter of aspirin particle should be in 50 μ m.
The present invention also provides the above-mentioned preparation method who kills wheel animalcule and protozoic compound medicament composition, and its step is as follows:
1) takes by weighing by weight ratio herbal raw material and drying and processing;
2) Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
3) Chinese herbal medicine and the anhydrous cupric sulfate after taking by weighing by weight ratio ultramicro grinding and processing, mixing, and get final product.
In the pharmaceutical composition of the present invention each drug component and consumption thereof are to control principle according to the dialectical opinion of Chinese veterinarian's prescription, get by repeatedly practising in a large number, and raw material comprises rhizoma zingiberis, stone-like omphalia, betel nut, Lappula echinata, thick wood-fern rhizome, the tuber of stemona, kuh-seng, anhydrous cupric sulfate.
Advantage of the present invention and beneficial effect are:
1) the present invention brings into play the combined effect of compound preparation, can kill fast and effectively the wheel animalcule in the breeding water body, and there is good preventive and therapeutic effect on shrimp crab breeding water body anoxic and the general pool of especially the wheel animalcule amount reproduction being caused, simultaneously Resting Eggs of Rotifers In The Water are had killing action;
2) compound medicament composition of the present invention can also be killed the protozoas such as Trichodina in the breeding water body, cup worm, oblique tube insect fast, can effectively prevent and treat the diseases such as cultured fishes gill rot that caused by protozoas such as Trichodinas;
3) compound medicament composition of the present invention is as main take Chinese herbal medicine, safe concentration is high, the conventional use can not damage cultivated animals, avoided pest control with insecticide safety of medicine scope little, easily cause the situation of the cultivated animals casualties to occur, simultaneously can the polluted-water environment, do not cause drug induced disease, do not produce the medicament residue of harm humans health etc. yet;
4) compound medicament composition of the present invention is being killed on wheel animalcule and the protozoas such as oblique tube insect, Trichodina, and dosage is few, and is easy to use, has avoided the shortcomings such as simple Chinese herbal medicine expelling parasite, insecticidal materials consumption be large; Because of the use of the technology such as ultramicro grinding, effectively raise effect of drugs, save herb resource, increase the cost performance of medicine.
, it should be understood that described embodiment only is for the present invention is described, rather than limit the scope of the invention by any way more specific description the present invention by the following example.
Embodiment
Embodiment 1
10 parts of rhizoma zingiberis, 15 parts of stone-like omphalias, 15 parts of betel nuts, 15 parts of Lappula echinatas, 30 parts of thick wood-fern rhizomes, 15 parts of the tubers of stemona, 15 parts of kuh-sengs, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
40 parts of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfates, mixing, and get final product.
Experimental example 2
20 parts of rhizoma zingiberis, 40 parts of stone-like omphalias, 40 parts of betel nuts, 40 parts of Lappula echinatas, 70 parts of thick wood-fern rhizomes, 40 parts of the tubers of stemona, 40 parts of kuh-sengs, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
120 parts of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfates, mixing, and get final product.
Embodiment 3
1 part of rhizoma zingiberis, 1 part of stone-like omphalia, 1 part of betel nut, 1 part of Lappula echinata, 1 part of thick wood-fern rhizome, 1 part of the tuber of stemona, 1 part of kuh-seng, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
1 part of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfate, mixing, and get final product.
Embodiment 4
40 parts of rhizoma zingiberis, 60 parts of stone-like omphalias, 60 parts of betel nuts, 60 parts of Lappula echinatas, 100 parts of thick wood-fern rhizomes, 60 parts of the tubers of stemona, 60 parts of kuh-sengs, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
200 parts of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfates, mixing, and get final product.
Embodiment 5
5 parts of rhizoma zingiberis, 10 parts of stone-like omphalias, 10 parts of betel nuts, 10 parts of Lappula echinatas, 20 parts of thick wood-fern rhizomes, 10 parts of the tubers of stemona, 10 parts of kuh-sengs, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
20 parts of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfates, mixing, and get final product.
Embodiment 6
30 parts of rhizoma zingiberis, 50 parts of stone-like omphalias, 50 parts of betel nuts, 50 parts of Lappula echinatas, 80 parts of thick wood-fern rhizomes, 50 parts of the tubers of stemona, 50 parts of kuh-sengs, drying and processing;
Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
150 parts of Chinese herbal medicine after taking by weighing ultramicro grinding and process by said ratio and anhydrous cupric sulfates, mixing, and get final product.
Observe example 1
Adopt the variable concentrations gradient solution of the embodiment of the invention 1 to the emergency toxicology experimental observation of gyalectiform Brachionus
Test is carried out in the test tube of laboratory.The gyalectiform Brachionus picks up from Jinnan District prawn culturing pond, Tianjin, and placing volume is the conical flask cultivation wheel animalcule of 250mL, and water temperature is between 25～28 ℃, and culture vessel places on the experimental bench of avoiding direct sunlight, throws something and feeds with Saccharomyces cerevisiae.
The compounding pharmaceutical water be running water through boiling cooling processing, drug concentration is made as 0 μ g/L, 50 μ g/L, 100 μ g/L, 150 μ g/L, 200 μ g/L, 300 μ g/L, 400 a μ g/L7 concentration gradient, each concentration gradient is established 3 repetitions.Get 21 test tubes and organize into groups respectively, add respectively the experimental liquid 10mL of each concentration gradient in every test tube, go out immature wheel animalcule with the phytoplankton net filtration, each adds randomly draw 30 not with the immature wheel animalcule of ovum at every test tube.Duration of test is not inflated, and a small amount of yeast of throwing something and feeding several times every day is respectively at 6,12,24h checks dead number of wheel animalcule of each group.Experiment repeats 3 times, medicine half lethal concentration 24h LC
50The employing probit method is tried to achieve.
Result of the test sees Table 1, and as can be seen from the table, along with drug concentration raises, the wheel animalcule lethality is in rising trend, when concentration below 100 μ g/L, the wheel animalcule lethality does not reach 50% behind the 24h, lethality is all lower; When drug concentration is higher than 150 μ g/L, the lethality of wheel animalcule surpasses 50%.Can try to achieve medicine with probit method is 24h LC to the half lethal concentration of wheel animalcule
50=134.07 μ g/L, its linear regression equation are Y=3.07X-1.54, LC
5095% credibility interval be 105.92～169.70 μ g/L.
Table 1 drug concentration and wheel animalcule mortality
Observe example 2
Adopt the medicine of the embodiment of the invention 2 preparations to the emergency toxicology experimental observation of Penaeus Vannmei
Test is carried out in large northern agricultural fish culture clinical labororatory.The test prawn is available from aquatic products wholesale market, Hongqiao, Beijing, and body length is 8～12cm, buys back to support in aquarium temporarily afterwards.The test water body is the running water through the sudden and violent gas disposal of 48h, any bait of not throwing something and feeding during supporting temporarily, and the water body inflation keeps water temperature at 25 ± 1 ℃.
Infusion method is adopted in test, establish altogether 5 concentration gradient medicine groups (0.5mg/L, 1.0mg/L, 2.0mg/L, 4.0mg/L and 8.0mg/L) and 1 blank group that does not add medicine, establish 3 repetitions (1 aquarium is 1 repetition) for every group, each aquarium is put Penaeus Vannmei 10 tails, specifically sees Table 2.After on-test, Continuous Observation, record prawn death toll.
Table 2 compound medicament composition is to Penaeus Vannmei emergency toxicology test grouping
The results are shown in Table 3.Control group and 0.5mg/L drug concentration group, prawn is movable normal, does not find the prawn phenomena of mortality; 4.0mg/L group, average mortality reaches 60%, 8.0mg/L group behind the 48h, and prawn is all dead behind the 24h.Trying to achieve medicine with probit method is LC to the 48h half lethal concentration of Penaeus Vannmei
50=3.19mg/L, 24h half lethal concentration are LC
50=3.31mg/L, press the Te Lunbao formula (
) to calculate this compound medicament composition be 0.92mg/L to the safe concentration of Penaeus Vannmei.
Penaeus Vannmei death condition under the table 3 different pharmaceutical concentration
Observe example 3
The embodiment of the invention 3 and meal thereof are observed the result for the treatment of of wheel animalcule disease
In June, 2007 is at Jinghai district shrimp culture pond, choose at random 60 mouthfuls of the fishing breeding ponds (area is 10～15 mu not to be waited) that the wheel animalcule disease has occured in various degree, the depth of water is 1～1.5 meter, and anoxic floating head phenomenon is in various degree arranged early morning, and microscopy finds that a large amount of wheel animalcules multiply.Take respectively following measures to prevent and treat, at first early morning alee the wheel animalcule close quarters concentrate (concentration 0.3ppm) and the compound meal of the compound medicament composition of embodiment 3 preparations of splashing, afternoon is (concentration 0.2ppm) and the compound meal of the compound medicament composition of full pool spilling head embodiment 3 preparations then, and aforesaid operations is repeated once after 3 days again in the interval.Record cultivation situation and microscopically every day and observe wheel animalcule quantity.Concrete condition sees Table 4.
Table 4 medicine is to prawn culturing pond wheel animalcule killing effect experimental result
In the table 4, compound medicament composition and the compound medicament composition meal of embodiment 3 preparations all have the good effect of killing to wheel animalcule in the prawn culturing pond, it is more thorough that the compound medicament composition of the present embodiment 3 is killed wheel animalcule, all do not find wheel animalcule after the medication but comparatively speaking.Therefore the compound medicament composition that adopts the present embodiment 3 obviously is better than compound medicament composition meal group killing on the wheel animalcule effect.
Observe example 4
Adopt the medicine of the embodiment of the invention 4 preparations that the result for the treatment of of shrimp culture pond fulminant wheel animalcule disease is observed
Present case is carried out result for the treatment of to the shrimp-cultivation pool pool, Jinnan District Ba Litai town, Tianjin fulminant wheel animalcule disease and is observed.In May, 2008, fulminant wheel animalcule disease occurs in 51 mouthfuls of prawn culturing ponds, Jinnan District Ba Litai town, Tianjin.The morbidity pond waters becomes shallow khaki by green suddenly, and the prawn intensity of feeding obviously weakens, and beginning is gathered in the edge, pond in a large number, and the floating head phenomenon occurs.One deck oil membranoid substance is arranged in the leeward, pond, observe water body adularescent point with transparent bottle and move about, microscopy is observed and is found a large amount of wheel animalcule corpse and the small-sized wheel animalcule of new breeding etc.
Discovery is investigated in the morbidity pond, locality life and the industrial sewage all hung oneself and tan by the sun processing in its water source, content of organics is higher, and mud is not cleared up in the morbidity pond throughout the year, Pond Silt thicker (deeply reaching 1 meter), the other feed of a large amount of high nutrition of throwing something and feeding in breeding process, water pollution is serious, and water quality sharply worsens.Be directed to this, we take comprehensive control measures.The compound medicament composition of elder generation's full pool spilling head the present embodiment 4 preparations, making water body Chinese traditional medicine concentration is 0.2ppm, splashed once in the interval in 3 days again; After one week, use again little ecological end of large north farming and change only bottom material of pond for breeding is improved.The result pond of falling ill is substantially controlled, and 43 mouthfuls of ponds in two months similar disease do not occur again, and there was a small amount of wheel animalcule breeding in other several mouthfuls of ponds after one month, and is after using the course for the treatment of this compound medicament composition, fully controlled again.
Observe example 5
The medicine of the employing embodiment of the invention 5 preparations is observed the result for the treatment of of the fish gill-rot diseases that the protozoas such as cultivating pool Trichodina, oblique tube insect cause
(1) 15 mu of the crane Long Hu of Xiangyin County, Hunan raisers' culturing pool, pond mean depth of water 1.2m puts the grass carp fry in a suitable place to breed.On April 25th, 2008, discovery had fry to flock together, and moved about around the limit, pond, presented " horse race " symptom, and fry begins mortality.Pick up fry and examine under a microscope, find that the fry gill and body surface have a large amount of Trichodinas parasitic.April 26 began to use this compound medicament composition, full pool spilling head makes the pond waters drug concentration reach 0.2ppm." horse race " symptom does not appear in second day, fry, begins to recover to ingest, and fry is dead obviously to be reduced.April 28 again full pool spilling head once, the water body drug concentration is 0.15ppm, after 2 days, it is normal that fry recovers substantially.
(2) the pond on a hill culturing pool of 180 mu of waters surface of changde, hunan suburban area river surname raiser, main foster grass carp, silver carp, flathead, crucian carp etc. have been put in collocation in a suitable place to breed.From in May, 2008, find every day to have a few tail grass carps dead, to about May 10 dead 50 tails.Observed May 11 and find to find tens of tails near the water surface in the lower air port of pool mouth, move about slowly, have difficulty in breathing, the body colour blackout.Throw something and feed and move about near the water surface for a long time after having a large amount of fishes to eat up food behind the feed, pick up several tails and observe, a large amount of mucus are arranged on the gill and the skin, the gill filament is red and swollen, and microscopically is observed and found to have on the gill a large amount of Trichodinas parasitic.May 12, this compound medicament composition of full pool spilling head made the water body drug concentration reach 0.25ppm, and the worm for fishing peace intestines cheek that adds simultaneously the farming of large north in the feed is peaceful.Second day, fish does not move about near the water surface afterwards for a long time at food, and the phenomena of mortality reduce to some extent; To May 14, fish death reduced to below ten tails, and full pool spilling head one deuterzooid compound medicament composition (concentration 0.2ppm) after May 15, does not have the dead generation of fish, fish food, movable normal substantially again.
(3) suburb, Huai’an, Jiangsu raiser puts 8 mu of Eriocheir sinensias in a suitable place to breed, and average weight is about 30g.On May 11st, 2008, find when throwing something and feeding bait that crab is slow in action, to ingest and weaken, food ration descends, and on indivedual crab chelas and the shell black splotch is arranged, and pulls indivedual frank crabs out, finds the parasitic a large amount of infusorians of body surface.May 12 this compound medicament composition of full pool spilling head, water body Chinese traditional medicine concentration is 0.25ppm, adds simultaneously the aquatic products multidimensional in feed; The next day deuterzooid compound medicament composition of splashing again, concentration is 0.2ppm.Next day, the crab food ration rose, and the morbidity crab reduces, and basic recovery was normal afterwards in 3 days.
Claims (6)
1. kill wheel animalcule and protozoic compound medicament composition for one kind, it is characterized in that it comprises the raw material of following weight proportioning: rhizoma zingiberis 1-40 part, stone-like omphalia 1-60 part, betel nut 1-60 part, Lappula echinata 1-60 part, thick wood-fern rhizome 1-100 part, tuber of stemona 1-60 part, kuh-seng 1-60 part, anhydrous cupric sulfate 1-200 part.
2. wheel animalcule and the protozoic compound medicament composition killed claimed in claim 1 is characterized in that described raw material weight proportioning is: rhizoma zingiberis 5-30 part, stone-like omphalia 10-50 part, betel nut 10-50 part, Lappula echinata 10-50 part, thick wood-fern rhizome 20-80 part, tuber of stemona 10-50 part, kuh-seng 10-50 part, anhydrous cupric sulfate 20-150 part.
3. wheel animalcule and the protozoic compound medicament composition killed claimed in claim 2 is characterized in that described raw material weight proportioning is: rhizoma zingiberis 10-20 part, stone-like omphalia 15-40 part, betel nut 15-40 part, Lappula echinata 15-40 part, thick wood-fern rhizome 30-70 part, tuber of stemona 15-40 part, kuh-seng 15-40 part, anhydrous cupric sulfate 40-120 part.
4. claim 1,2 or 3 described wheel animalcule and the protozoic compound medicament compositions killed is characterized in that it is a kind of powder.
5. wheel animalcule and the protozoic compound medicament composition killed claimed in claim 4 is characterized in that the diameter of aspirin particle of powder is in 50 μ m.
6. preparation method who kills wheel animalcule and protozoic compound medicament composition as claimed in claim 1 is characterized in that step is as follows:
1) takes by weighing by weight ratio herbal raw material and drying and processing;
2) Chinese herbal medicine behind the drying and processing is carried out ultramicro grinding;
3) Chinese herbal medicine and the anhydrous cupric sulfate after taking by weighing by weight ratio ultramicro grinding and processing, mixing, and get final product.
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102886005A (en) * | 2011-07-20 | 2013-01-23 | 天津瑞贝特科技发展有限公司 | Chinese medicinal composition for treating parasites in fishes cultivated in sea fresh water and preparation method thereof |
| CN102939875A (en) * | 2012-10-31 | 2013-02-27 | 薛命雄 | Method for biologically treating spirulina rotatoria by Chinese herbal medicine gelsemium elegans |
| CN103907627B (en) * | 2013-01-09 | 2015-07-01 | 中国科学院海洋研究所 | Application of tetracyclic triterpenoids in preparation of low-dosage rotifer insecticides |
| CN104686594A (en) * | 2013-12-06 | 2015-06-10 | 天津嘉创生物科技有限公司 | Traditional Chinese medicine composition capable of killing rotifer in water and preparation method thereof |
| CN104322415B (en) * | 2014-11-03 | 2016-05-11 | 苏修之 | A kind of method of the water tank culturing rice field eel that prevents trichodinasis |
| CN105012610A (en) * | 2015-08-06 | 2015-11-04 | 杨壮志 | Superfine powder traditional Chinese veterinary medicine for treating trichodiniasis of loach and preparing method |
| CN105981749A (en) * | 2016-03-11 | 2016-10-05 | 湖北隶德生物工程有限公司 | Medicament for rapidly removing rotifers in culture water body |
| CN105943594A (en) * | 2016-06-23 | 2016-09-21 | 重庆市宏东农业综合开发有限公司 | Composition for treating apiosoma of loaches |
| CN106852420A (en) * | 2016-12-31 | 2017-06-16 | 新昌县田野泉养殖技术开发有限公司 | Culture of Penaeus vannamei feed and preparation method thereof |
| CN107744550A (en) * | 2017-10-29 | 2018-03-02 | 南宁学院 | A kind of composition for preventing and treating mandarin sturgeon trichodinasis and preparation method thereof |
-
2008
- 2008-10-06 CN CN 200810223487 patent/CN101711528B/en active Active
Non-Patent Citations (6)
| Title |
|---|
| 22种植物提取物及其6种化合物对鱼类指环虫的杀灭研究;王高学等;《西北植物学报》;20061228(第12期);2567-2573页 * |
| 孙克良.胆道驱蛔定痛汤治疗胆道蛔虫症.《陕西中医》.1984,(第05期), |
| 王高学等.22种植物提取物及其6种化合物对鱼类指环虫的杀灭研究.《西北植物学报》.2006,(第12期), |
| 胆道驱蛔定痛汤治疗胆道蛔虫症;孙克良;《陕西中医》;19840505(第05期);45页 * |
| 贾锐.驱绦饮治验.《陕西中医》.1985,(第08期), |
| 驱绦饮治验;贾锐;《陕西中医》;19850805(第08期);367页 * |
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| CN101711528A (en) | 2010-05-26 |
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Effective date of registration: 20220804 Address after: 101407 Beijing city Huairou District Yanqi Economic Development Zone No. 10 North Street Patentee after: Beijing Dabeinong Animal Health Care Technology Co.,Ltd. Patentee after: Shaoshan Dabeinong Animal Medicine Co.,Ltd. Address before: 100083, Zhongguancun building, No. 27 Zhongguancun street, Beijing, Haidian District, China, 14 floor Patentee before: BEIJING DABEINONG TECHNOLOGY GROUP Co.,Ltd. Patentee before: Beijing Dabeinong Animal Health Care Technology Co.,Ltd. Patentee before: Shaoshan Dabeinong Animal Medicine Co.,Ltd. |