CN101686917A - 带有可可脂和二羟基丙基铵盐的个人护理组合物 - Google Patents
带有可可脂和二羟基丙基铵盐的个人护理组合物 Download PDFInfo
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- CN101686917A CN101686917A CN200880015028A CN200880015028A CN101686917A CN 101686917 A CN101686917 A CN 101686917A CN 200880015028 A CN200880015028 A CN 200880015028A CN 200880015028 A CN200880015028 A CN 200880015028A CN 101686917 A CN101686917 A CN 101686917A
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- cocoa butter
- personal care
- salt
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Abstract
提供了一种个人护理组合物，当该组合物施用到皮肤时，其提供了改进的半透明性来显示健康的肤色。该组合物基于二羟基丙基季铵盐和可可脂的混合物。
Description
发明背景
本发明涉及个人护理配制剂，特别是用于面部和身体的产品，其使得下面的皮肤呈现出可见的健康自然颜色。
生命活力通常显现在一个人的脸上。吸引人的特征包括一个人所拥有的皮肤的天然外表。半透明性是化妆品配制剂的一个性能，其使得光线转移到表皮中，以使下面的皮肤可见。这包括了血管的清楚呈现。略带粉红色的健康肤色源自于其中。
US专利7175836B1(Hart等人)公开了一种含有共轭亚油酸的油包水化妆品组合物，其显现出具有提高亮度和光彩的作用。
本发明的一个目标是提供一种化妆品组合物，其特别是通过达到改进的半透明性而带来了一种天然外表的健康颜色。
发明内容
提供了一种个人护理组合物，其包括：
(i)0.05-30重量％的结构AB的二羟基丙基季铵盐，
其中A是盐AB的阳离子带电成分，B是盐AB的阴离子带电成分，并且A具有单个季铵化的氮原子、至少两个羟基基团和不高于250的分子量；
(ii)0.01-30重量％的可可脂。
具体实施方式
目前已经发现通过一种包括二羟基丙基季铵盐和可可脂的组合物，能够赋予皮肤半透明性。
因此，本发明一个重要的原料是结构AB的二羟基丙基季铵盐，其中A是盐AB的阳离子带电成分，B是盐AB的阴离子带电成分，A具有一个季铵化的氮原子、至少两个羟基基团和下面的分子量：不高于250但是优选不高于200，并且最理想是不高于170。
阴离子带电成分B可以是有机或者无机的，并且限定该材料是化妆上可接受的。典型的无机阴离子是卤化物(卤离子)，硫酸根(盐)，磷酸根(盐)，硝酸根(盐)和硼酸根(盐)。最优选的是卤化物，特别是氯化物。有机阴离子抗衡离子包括甲基硫酸根(盐)，甲苯酰硫酸根(盐)，乙酸根(盐)，柠檬酸根(盐)，酒石酸根(盐)，乳酸根(盐)，葡糖酸根(盐)和苯磺酸根(盐)。负性带电成分B的数目和电荷足以中和成分A的正电荷。
一种优选的季铵盐的实施方案是二羟基丙基三(C1-C3烷基或者羟烷基)铵盐。
这些盐可以在多种合成方法中获得，最特别是通过氯羟丙基三(C1-C3烷基或者羟烷基)铵盐的水解来获得。季铵化的铵基上的C1-C3烷基或者羟烷基成分通常是甲基，乙基，正丙基，异丙基，羟乙基，羟甲基及其混合物。特别优选的是三甲基铵基，其在INCI命名法中被称为“三甲基铵(trimonium)”基团。最优选的物质是1，2-二羟基丙基三甲基氯化铵，其中C1-C3烷基是甲基基团。
另外一种有用的季铵盐物质是结构(I)的材料。
季铵盐的量范围可以是个人护理组合物的0.05-30重量％，优选0.1-25重量％，更优选1-15重量％，最理想的是5-10重量％。
本发明另外一种重要的成分是可可脂。术语“可可脂”也称作可可豆油(可可脂(theobroma oil))。这种材料是通过对可可豆进行榨出、煎煮或者溶剂萃取而获得的。尤其通常的是一种生产方法，在其中将可可豆在热或者冷板之间进行挤压。典型的性能为比重是0.858-0.864(100/25℃)，熔点是30-35℃，折射率(n40/D)是1.4537-1.4585；皂化值是188-200和碘值是32-43。可可脂的量可以是该个人护理组合物的0.01-30重量％，优选0.1-15重量％，更优选0.5-10重量％，最理想是1-5重量％。
润肤剂材料可以用作化妆上可接受的载体。这些材料可以处于下面的形式中：天然或者合成的酯类、烃类和有机硅。润肤剂的量可以是该个人护理组合物的下面范围中的任何量：0.1-60重量％，优选1-30重量％。
其中，所述的酯润肤剂是：
(a)具有10-24个碳原子的饱和脂肪酸的烷基酯。其例子包括新戊酸山萮基酯，异壬酸异壬基酯(isononyl isonanonoate)，十四烷酸异丙酯和硬脂酸辛基酯。
(b)醚-酯类例如乙氧基化的饱和脂肪醇的脂肪酸酯。
(c)多羟基醇酯。单-和二-脂肪酸乙二醇酯，单-和二-脂肪酸二甘醇酯，聚乙二醇(200-6000)单-和二-脂肪酸酯，单-和二-脂肪酸丙二醇酯，聚丙二醇2000单硬脂酸酯，乙氧基化的单硬脂酸丙二醇酯，单-和二-脂肪酸甘油基酯，聚甘油聚脂肪酯，乙氧基化的单-硬脂酸甘油基酯，单硬脂酸1，3-丁二醇酯，二硬脂酸1，3-丁二醇酯，聚氧乙烯多元醇脂肪酸酯，脂肪酸脱水山梨糖醇酯，和聚氧乙烯脂肪酸脱水山梨糖醇酯是令人满意的多羟基醇酯。特别有用的是季戊四醇，三羟甲基丙烷和C1-C30醇的新戊二醇酯。
(d)蜡酯例如蜂蜡，鲸蜡和三山萮蜡。
(e)脂肪酸的糖酯例如聚山嵛酸蔗糖酯和聚棉籽酸蔗糖酯。
天然酯类润肤剂主要基于单-、二-和三-甘油酯。代表性的甘油酯包括葵花籽油，棉花籽油，琉璃苣油，琉璃苣籽油，樱草油，蓖麻油和氢化蓖麻油，米糠油，大豆油，橄榄油，红花油，乳木果油，荷荷芭油(jojobaoil)及其组合。动物来源的润肤剂的代表是羊毛脂油和羊毛脂衍生物。该天然酯的量是个人护理组合物的0.1-20重量％。
烃类(其是合适的化妆上可接受的载体)包括矿脂，矿物油，C11-C13异链烷烃，聚丁烯，特别是异十六烷，如市售自Presperse Inc的Permethyl 101A。
具有10-30个碳原子的脂肪酸也适于作为化妆上可接受的载体。这个种类示例性的是壬酸，月桂酸，十四烷酸，棕榈酸，硬脂酸，异硬脂酸，油酸，亚麻油酸，亚麻酸，羟基硬脂酸和山嵛酸。
广泛的多种有机硅可以用作本发明的润肤剂，该有机硅包括在室温时是液体、固体或者半固体浓度的材料。液体有机硅包括硅油，其可以被分为挥发性和非挥发性的种类。作为此处使用的，术语“挥发性”指的是这些材料在环境温度时具有可测量的蒸气压。挥发性硅油优选是选自环状(聚环甲基硅氧烷)或者线性聚二甲基硅氧烷，其含有3-9个，优选4-5个硅原子。市售的挥发性硅油包括DC200，DC244，DC245，DC344和DC345，全部由Dow Coming Corporation提供；SF-1204，SF-1202Silicone Fluids，来自GE Silicones的GE7207和GE7158；和来自SWSSilicones Corporation的SWS-03314。
有用的非挥发性硅油包括聚烷基硅氧烷，聚烷基芳基硅氧烷和聚醚硅氧烷共聚物。此处有用的本质上非挥发性的聚烷基硅氧烷包括例如25℃时粘度为5×10-6-0.1m2/s的聚二甲基硅氧烷。其中，在本发明的组合物中有用的非挥发性润肤剂优选是25℃时粘度为1×10-5-4×10-4m2/s的聚二甲基硅氧烷。代表性的市售材料包括在Viscasil系列下售自G.E.Silicones和在DC200系列下售自Dow Coming Corporation的聚烷基硅氧烷。聚烷基芳基硅氧烷包括聚甲基苯基硅氧烷例如SF1075甲基-苯基流体和556化妆品级流体(售自Dow Coming Corporation)也可以是有用的。示例性的聚氧亚烷基醚共聚物是市售自G.E.Silicones的SF1066，和获自Shin-Etsu的PEG-10聚二甲基硅氧烷。
另外一个种类的非挥发性有机硅是乳化的和非乳化的有机硅弹性体。这个种类代表性的是聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物，市售的如Dow Coming 9040，General Electric SFE 839，和Shin-Etsu KSG-18。有机硅蜡例如Silwax WS-L(聚二甲基硅氧烷共聚多元醇月桂酸酯)也会是有用的。
有机硅的量可以是个人护理组合物的0.05-50重量％，优选是0.5-40重量％，更优选是2-20重量％，最理想的是5-12重量％。
表面活性剂也可以存在于本发明的组合物中。当存在时，表面活性剂的总浓度是个人护理组合物的0.1-50重量％，优选1-25重量％，最理想的是1-10重量％，并且主要的取决于个人护理品的类型。该表面活性剂可以选自阴离子，非离子，阳离子和两性离子表面活性剂。特别优选的非离子表面活性剂是具有选自下面的这些：用基于每摩尔疏水物为2-100mol的环氧乙烷或者环氧丙烷缩合的C10-C20脂肪醇或者酸疏水物；用2-20mol烯化氧缩合的C2-C10烷基酚；单-和二-脂肪酸乙二醇酯；脂肪酸单甘油酯；脱水山梨糖醇，单-和二-C8-C20脂肪酸；和聚氧乙烯脱水山梨糖醇及其组合。烷基多糖苷和糖化脂肪酰胺(例如甲基葡糖酰胺)和三烷基氧化胺也是合适的非离子表面活性剂。
优选的阴离子表面活性剂包括皂类，烷基醚硫酸盐和磺酸盐，烷基硫酸盐和磺酸盐，烷基苯磺酸盐，烷基和二烷基磺化琥珀酸盐，C8-C20酰基异硫代硫酸盐，C8-C20烷基醚磷酸盐，C8-C20肌氨酸盐，C8-C20酰基乳酰乳酸盐，磺化乙酸盐及其组合。
有用的两性离子表面活性剂包括椰油酰胺丙基甜菜碱，C12-C20三烷基甜菜碱，月桂基两性醋酸钠和月桂基二两性醋酸钠。
辅助性润湿剂可以用于本发明中。这些润湿剂通常是多羟基醇类型的材料。典型的多羟基醇包括甘油，丙二醇，二丙二醇，聚丙二醇，聚乙二醇，山梨糖醇，羟丙基山梨糖醇，己二醇，1，3-丁二醇，异丙二醇，1，2，6-己三醇，乙氧基化甘油，丙氧基化甘油及其混合物。辅助性润湿剂的量可以是个人护理组合物的0.2-40重量％，优选1-25重量％，最优选2-15重量％范围内的任意值。最优选的是甘油作为辅助性润湿剂或者增湿剂。
防晒剂也可以包括在本发明的组合物中。特别优选的是这样的材料，如肉桂酸乙基己基对甲氧基酯，可用的如丁基甲氧基二苯甲酰基甲烷(Avobenzene)，可用的如和苯甲酮-3，也称为羟苯甲酮。无机防晒剂活性物质可以使用例如微细的(1-100nm)二氧化钛和氧化锌。当存在时，防晒剂的量通常的范围可以是个人护理组合物的0.1-30重量％，优选2-20重量％，最理想的是4-10重量％。
防腐剂可以期望的混入到本发明的个人护理组合物中，来保护抗潜在的有害的微生物的生长。特别优选的防腐剂是苯氧基乙醇，对羟基苯甲酸甲基酯，对羟基苯甲酸丙酯，咪唑烷基脲，二羟甲基二甲基乙内酰脲，乙二胺四乙酸盐(EDTA)，脱水乙酸钠，甲基氯异噻唑啉酮，甲基异噻唑啉酮，碘丙基丁基氨基甲酸酯和苄醇。应当根据组合物的用途和防腐剂与其他成分之间可能的不相容性来选择防腐剂。防腐剂优选的用量范围是该个人护理组合物的0.0001-2重量％。
本发明的组合物可以包括维生素。示例性的维生素是维生素A(视黄醇)，维生素B2，维生素B3(烟酰胺)，维生素B6，维生素C，维生素E，叶酸和维生素H。也可以使用维生素的衍生物。例如，维生素C衍生物包括四异棕榈酸抗坏血酸酯，磷酸抗坏血酸镁和抗坏血酸糖苷。维生素E的衍生物包括维生素E乙酸酯，维生素E棕榈酸酯和维生素E亚油酸酯。也可以使用DL-泛酰醇和衍生物。当存在于本发明的组合物中时，维生素的总量范围可以是该个人护理组合物的0.001-10重量％，优选0.01-1重量％，最理想的是0.1-0.5重量％。
另外一种类型的有用物质可以是酶例如淀粉酶，氧化酶，蛋白酶，脂肪酶，纤维素酶，弹性蛋白酶及其组合。
皮肤增亮化合物可以包括在本发明的组合物中。示例性的物质是胎盘提取物，乳酸，烟酰胺，熊果苷，曲酸，阿魏酸，豌豆(Actiwhite LS9808，来自Cognis)，间苯二酚和衍生物，包括4-取代的间苯二酚及其组合。这些试剂的量可以是个人护理组合物的0.1-10重量％，优选0.5-2重量％。
无日光晒黑剂(sunless tanner)也可以配制到本发明的组合物中。这个种类代表性的是二羟基丙酮，赤藓酮糖，三羟乙基芦丁，黑色素，mahkanni及其混合物。辅助剂包括氨基酸，缩氨酸，胺及其组合。无日光晒黑剂的量可以是个人护理组合物的0.1-15重量％，优选0.5-10重量％，最理想的是1-5重量％。
脱落促进剂可以存在。示例性是α-羟基羧酸和β-羟基羧酸。术语“酸”表示不但包括游离酸，而且包括盐和其的C1-C30烷基或者芳基酯，以及从环状或线性内酯结构中除去水而产生的内酯。代表性的酸是乙醇酸，乳酸和苹果酸。水杨酸是代表性的β-羟基羧酸。当存在时，这些材料的量可以是个人护理组合物的0.01-15重量％。
多种草药提取物可以任选的包括在本发明的组合物中。该提取物可以是在溶剂中水溶性的或者水不溶性的，其分别是亲水性或者疏水性的。水和乙醇是优选的提取物溶剂。示例性提取物包括来自下面的这些：绿茶、甘菊、欧亚甘草、芦荟、葡萄籽、蜜柑(Citrus unshui)、柳树皮、鼠尾草、百里香和迷迭香。
还可以包括这样的材料，如硫辛酸，视黄氧基(retinoxy)三甲基硅烷(在Silcare 1 M-75商标下获自Clariant Corp.)，脱氢表雄甾酮(DHEA)及其组合。神经酰胺(包括神经酰胺1，神经酰胺3，神经酰胺3B和神经酰胺6)以及仿神经酰胺也可以是有用的。这些材料的量可以是个人护理组合物的0.000001-10重量％，优选0.0001-1重量％。
着色剂、遮光剂和研磨剂也可以包括在本发明的组合物中。每个这些物质的范围可以是该个人护理组合物的0.05-5重量％，优选0.1-3重量％。
本发明的个人护理组合物可以处于任何的形式中。这些形式可以包括洗液、霜剂、滚擦式配制剂、贴剂、摩丝、气雾剂和非气雾剂喷剂和织物(例如无纺织物)-施用的配料。
广泛的多种包装材料可以用来存储和传递该个人护理组合物。包装材料通常取决于个人护理最终用途的类型。例如，留在皮肤上的洗液和霜剂，无日光晒黑剂和沐浴露通常使用塑料容器，该容器在分配端具有盖子封闭的开口。典型的盖子是螺帽、非气雾剂泵和上翻式铰链的盖子。由压缩气体加压的并且具有喷嘴的金属罐头用作可喷射形式的个人护理品的包装材料。梳洗棒(Toilet bars)可以具有由纤维质的或者塑料包装纸组成的包装材料或者处于纸盒中，或者甚至包装在热缩塑料膜中。
此处提及的全部文献，包括全部的专利、专利申请和出版的公开文献以它们整个在此引入本发明中作为参考。
应当指出的是在所规定浓度或者量的任何范围内，任何具体的更高的浓度可以与任何更低的浓度或者量进行组合。
下面的实施例将更充分的说明本发明的实施方案。除非另有指示，否则此处和附加的权利要求中所提及的全部的份数、百分比和比例是重量单位的。
实施例1
表I中概括了一种本发明代表性的化妆品洗液形式的个人护理组合物。
表I
实施例2
这里表示的是一种混有本发明的季铵盐和可可脂的皮肤霜剂。
表II
| 成分 | 重量％ |
| 甘油 | 10.00 |
| 烟酰胺 | 5.00 |
| 二羟基丙基三甲基氯化铵 | 5.00 |
| 可可脂 | 5.00 |
| Permethyl 101A1 | 3.00 |
| Sepigel 3052 | 2.50 |
| Q2-14033 | 2.00 |
| 亚麻子油 | 1.33 |
| Arlatone 21214 | 1.00 |
| 十六烷醇CO-1695 | 0.72 |
| SEFA棉花酸酯5 | 0.67 |
| 维生素E乙酸酯 | 0.50 |
| 泛酰醇 | 0.50 |
| 硬脂醇 | 0.48 |
| 二氧化钛 | 0.40 |
| EDTA二钠 | 0.10 |
| Glydant Plus6 | 0.10 |
| PEG-100硬脂酸酯 | 0.10 |
| 硬脂酸 | 0.10 |
| 净化水 | 余量 |
1异十六烷，Presperse Inc.，South Plainfield，新泽西
2聚丙烯酰胺(和)C13-14异链烷烃(和)Laureth-7，SeppicCorporation，Fairfield，新泽西
3聚二甲基硅氧烷(和)聚二甲基硅氧烷醇，Dow Coming Corp.Midland，M1
4脱水山梨糖醇单硬脂酸酯和蔗糖椰油酸酯，ICIAmericas Inc.，Wilming-n，德国
5脂肪酸的蔗糖酯
6DMDM乙内酰脲(和)碘丙基丁基氨基甲酸酯，Lonza Inc.，Fairlawn，新泽西
实施例3
表III的配方是混有本发明的季铵盐和可可脂另外一种示例性的化妆品组合物。
表III
| 成分 | 重量％ |
| 聚有机硅-12 | 29 |
| 聚环甲基硅氧烷 | 59 |
| 甘油 | 10 |
| 二羟基丙基三甲基氯化铵 | 1.2 |
| 聚二甲基硅氧烷共聚多元醇 | 0.5 |
| 可可脂 | 0.3 |
实施例4
表IV报告了一种混有本发明的季铵盐和可可脂的相对无水组合物。
表IV
| 成分 | 重量％ |
| 聚环甲基硅氧烷 | 60.65 |
| 甘油 | 11.00 |
| 聚二甲基硅氧烷 | 10.10 |
| 角鲨烷 | 6.00 |
| 可可脂 | 4.00 |
| 二羟基丙基三甲基氯化铵 | 5.00 |
| 异硬脂酸 | 1.90 |
| 琉璃苣籽油 | 0.90 |
| 棕榈酸视黄基酯 | 0.25 |
| 神经酰胺6 | 0.10 |
| 维生素E | 0.10 |
实施例5
表V概括了一种带有适于本发明的季铵盐和可可脂的气雾剂包装的发泡清洁剂。
表V
| 成分 | 重量％ |
| 葵花籽油 | 10.00 |
| 甘油 | 10.00 |
| 马来酸化的大豆油 | 5.00 |
实施例6
描述了本发明的一种一次使用的、单一用途的个人护理湿巾产品。制备了一种70/30聚酯/人造丝无纺湿巾，其的重量是1.8g，尺寸是15cm×20cm。在这个湿巾上充入下表V1所示的1.0g的组合物，该组合物包括季铵盐和有机硅微乳液。
表VI
| 成分 | 重量％ |
| 二羟基丙基三甲基氯化铵 | 4.00 |
| 甘油 | 12.00 |
| 可可脂 | 1.00 |
| 癸酰基两性二乙酸二钠 | 1.00 |
| 葡糖酸内酯 | 0.90 |
| 有机硅微乳液 | 0.85 |
| 山榆 | 0.50 |
| PEG-400氢化蓖麻油 | 0.50 |
| 香味剂 | 0.20 |
| 维生素E乙酸酯 | 0.001 |
| 水 | 余量 |
实施例7
本发明的一种示例性的梳洗棒表示在表V1I中。
表VII
| 成分 | 重量％ |
| 钠皂(85/15牛脂/椰油) | 77.77 |
| 二羟基丙基三甲基氯化铵 | 3.50 |
| 可可脂 | 2.00 |
| 氯化钠 | 0.77 |
| 二氧化钛 | 0.40 |
| 香味剂 | 1.50 |
| EDTA二钠 | 0.02 |
| 依替膦酸钠 | 0.02 |
| 荧光增白剂 | 0.024 |
| 水 | 余量 |
实施例8
这里报道了一种混有本发明的季铵盐和可可脂的身体洗液。
表VIII
实施例9
其中报道了半透明性测量。皮肤是一种半透明物质。当光入射到皮肤上时，一小部分光在皮肤表面上被反射和散射。大部分光继续透入到皮肤中来散射，这改变了传播方向。一部分光同样被皮肤发色体例如在皮肤更深层的血液和黑色素所吸收。光在皮肤中的散射改变了光路，并且产生了光从它的初始路径的漫射。在多次散射之后，一些光没有被吸收，并且返回皮肤表面，选出到反射空间中。这个部分被称作漫反射光。这个漫反射光通过了血液和黑色素的吸收，因此带有该吸附剂的特征信号，这赋予皮肤独特的颜色。
总的皮肤光谱反射率是在皮肤表面处及其下面的反射率的总和。半透明性是皮肤内的光透射和扩散。它取决于皮肤的光学散射和吸收性能。当散射和吸收系数高时，半透明性是低的。这对应于硬的和不透明的皮肤外观，并且具有更加不平坦的纹理结构。当散射和吸收系数低时，半透明性是高的。这对应于柔软的皮肤外观，并且具有更加平坦的纹理结构。
半透明性与光谱反射率有关。皮肤的半透明性随着表面散射的降低和更多的光透入到皮肤而提高。所以，皮肤半透明性的提高对应于总光谱反射率的降低。
测试是用Minolta分光光度计CM-2500C来进行的。这个仪器利用了两个脉冲的氙气灯作为光源，并且在360-740nm的波长范围内运行。颜色空间是用公知的L*a*b*来定义的。测试是通过将该分光光度计探针轻轻的与测试区域接触，并且取三个重复的反射率光谱来进行的。这些测试是在产品施用之后10分钟、1小时和3小时进行的。
数据分析如下：
1.反射率光谱变化＝“施用后的光谱”-“基线光谱(在施用之前)”。
2.ΔL*＝施用后的L*-基线的L*。
3.半透明性变化是通过ΔL*来测量的；降低的L*表现更多的半透明性。
4.相对半透明性是通过标准化的ΔL*来测量的。
标准化的ΔL*＝ΔL*/(样品A的ΔL*和样品B的ΔL*之和)
施用区域是前臂上的三个身体部位(4×5cm2)。样品和剂量如下。
i.位置1：施用2mg/cm2样品A
ii.位置2：施用0.5mg/cm2样品B
iii.位置3：施用2mg/cm2样品A和0.5mg/cm2样品B(样品A和样品B一起混合在位置3上)
样品A是一种12％的二羟基丙基三甲基氯化铵的水溶液。样品B是50％的可可脂的载体油溶液(该载体油是辛酸羊蜡酸三甘油酯)。
效力测试报告在表IX中。标准化的半透明性值表示了基线和样品施用的反射率光谱之间的反射率变化。
表IX
| 样品 | 活性成分 | 标准化的半透明性 |
| A(2mg/cm2) | 二羟基丙基三甲基氯化铵 | 0.8 |
| B(0.5mg/cm2) | 可可脂 | 0.2 |
| A+B(2mg/cm2样品A和0.5mg/cm2样品B的混合物) | 二羟基丙基三甲基氯化铵和可可脂的混合物 | 1.42 |
可可脂本身(样品B)性仅仅具有对于半透明较少的积极作用。样品A是二羟基丙基三甲基氯化铵活性剂，其提供明显更强的半透明性的提高。二羟基丙基三甲基氯化铵和可可脂的组合出人意料之外的得到了1.42的值，这显示了一种显著提高的健康肤色性能。
Claims (5)
1.一种个人护理品，其包含：
(i)0.05-30重量％的结构AB的二羟基丙基季铵盐，
其中A是盐AB的阳离子带电成分，B是盐AB的阴离子带电成分，并且A具有单个季铵化的氮原子、至少两个羟基基团和不高于250的分子量；
(ii)0.01-30重量％的可可脂。
2.根据权利要求1的组合物，其中该季铵盐是二羟基丙基三(C1-C3烷基)铵盐。
3.根据权利要求2的组合物，其中该盐是二羟基丙基三甲基氯化铵。
4.根据任何一个前述权利要求的组合物，其中可可脂的存在量是0.5-10重量％。
5.根据权利要求1的组合物，其中该二羟基丙基季铵盐的存在量是1-15重量％。
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| JP3880907B2 (ja) * | 2001-08-31 | 2007-02-14 | オリンパス株式会社 | 内視鏡用縫合器 |
| MXPA04008818A (es) * | 2002-03-12 | 2004-11-26 | Playtex Products Inc | Composiciones de locion. |
| US7527806B2 (en) * | 2002-04-26 | 2009-05-05 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Personal care article with distinct active zone |
| KR100552245B1 (ko) * | 2003-10-24 | 2006-02-14 | 주식회사 코리아나화장품 | 예덕나무 추출물을 함유하는 주름 개선 화장료 조성물 |
| US7442674B2 (en) * | 2004-03-31 | 2008-10-28 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Beauty wash product compositions delivering enhanced visual benefits to the skin with specific optical attributes |
| US8124063B2 (en) * | 2004-10-25 | 2012-02-28 | Conopco, Inc. | Method for moisturizing human skin using dihydroxypropyltri(C1-C3 alkyl) ammonium salts |
| BRPI0515846B1 (pt) | 2004-10-25 | 2020-10-20 | Unilever N.V | composição de higiene pessoal |
| US20060088496A1 (en) * | 2004-10-25 | 2006-04-27 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Personal care compositions with salts of hydroxypropyl trialkylammonium substituted mono-saccharide |
| US7282471B2 (en) * | 2005-09-08 | 2007-10-16 | Conopco, Inc. | Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts |
| US7087560B2 (en) * | 2004-10-25 | 2006-08-08 | Unilever Home & Personal Care Usa, A Division Of Conopco, Inc. | Personal care composition with salts of dihydroxypropyltri(C1-C3 alkyl) ammonium monosubstituted polyols |
| US7176172B2 (en) * | 2004-10-25 | 2007-02-13 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Quaternary ammonium polyol salts as anti-aging actives in personal care compositions |
| US7659233B2 (en) | 2004-10-25 | 2010-02-09 | Conopco, Inc. | Personal care compositions with silicones and dihydroxypropyl trialkyl ammonium salts |
| DE102005003708B4 (de) | 2005-01-20 | 2017-11-09 | Beiersdorf Ag | Verwendung von Hautpflegeöl mit Kakaobutter |
| US7175836B1 (en) | 2005-12-23 | 2007-02-13 | Conopco, Inc. | Oil continuous phase cosmetic emulsions with conjugated linoleic acid |
-
2007
- 2007-05-30 US US11/755,008 patent/US8206754B2/en active Active
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2008
- 2008-01-21 MX MX2009011864A patent/MX2009011864A/es active IP Right Grant
- 2008-01-21 WO PCT/EP2008/050614 patent/WO2008145410A1/en active Application Filing
- 2008-01-21 DE DE602008002584T patent/DE602008002584D1/de active Active
- 2008-01-21 ES ES08708018T patent/ES2350624T3/es active Active
- 2008-01-21 AT AT08708018T patent/ATE481082T1/de not_active IP Right Cessation
- 2008-01-21 AU AU2008258099A patent/AU2008258099B2/en not_active Ceased
- 2008-01-21 CA CA2687738A patent/CA2687738C/en active Active
- 2008-01-21 JP JP2010509753A patent/JP5378363B2/ja not_active Expired - Fee Related
- 2008-01-21 KR KR1020097023590A patent/KR101163843B1/ko not_active IP Right Cessation
- 2008-01-21 ZA ZA200907500A patent/ZA200907500B/xx unknown
- 2008-01-21 CN CN2008800150285A patent/CN101686917B/zh not_active Expired - Fee Related
- 2008-01-21 EP EP08708018A patent/EP2148648B1/en not_active Not-in-force
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2013
- 2013-09-24 JP JP2013196522A patent/JP2014012728A/ja not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103140469A (zh) * | 2010-09-30 | 2013-06-05 | 陶氏环球技术有限责任公司 | 季铵多羟基化合物及其在个人护理组合物中的用途 |
| CN103140469B (zh) * | 2010-09-30 | 2016-03-02 | 陶氏环球技术有限责任公司 | 季铵多羟基化合物及其在个人护理组合物中的用途 |
| CN104131159A (zh) * | 2014-08-13 | 2014-11-05 | 铜陵有色金属集团股份有限公司金冠铜业分公司 | 冰铜的粒化收集装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2148648B1 (en) | 2010-09-15 |
| AU2008258099A1 (en) | 2008-12-04 |
| JP5378363B2 (ja) | 2013-12-25 |
| US8206754B2 (en) | 2012-06-26 |
| WO2008145410A1 (en) | 2008-12-04 |
| JP2010528077A (ja) | 2010-08-19 |
| KR20090130205A (ko) | 2009-12-18 |
| ZA200907500B (en) | 2010-07-28 |
| CA2687738A1 (en) | 2008-12-04 |
| CA2687738C (en) | 2012-10-09 |
| MX2009011864A (es) | 2010-01-14 |
| KR101163843B1 (ko) | 2012-07-11 |
| DE602008002584D1 (de) | 2010-10-28 |
| US20080299237A1 (en) | 2008-12-04 |
| EP2148648A1 (en) | 2010-02-03 |
| CN101686917B (zh) | 2012-03-21 |
| AU2008258099B2 (en) | 2010-12-02 |
| JP2014012728A (ja) | 2014-01-23 |
| ES2350624T3 (es) | 2011-01-25 |
| ATE481082T1 (de) | 2010-10-15 |
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