CN101680029B - 核酸检测 - Google Patents

核酸检测 Download PDF

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Publication number
CN101680029B
CN101680029B CN200880012820.5A CN200880012820A CN101680029B CN 101680029 B CN101680029 B CN 101680029B CN 200880012820 A CN200880012820 A CN 200880012820A CN 101680029 B CN101680029 B CN 101680029B
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primer
enrichment
nucleic acid
nucleotide
amplification
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CN101680029A (zh
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富国良
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Guangzhou Zhenfu Technology Co ltd
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Oxitec Ltd
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN200880012820.5A 2007-03-01 2008-02-29 核酸检测 Active CN101680029B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0703996.9 2007-03-01
GB0703996A GB0703996D0 (en) 2007-03-01 2007-03-01 Nucleic acid detection
PCT/GB2008/000707 WO2008104794A2 (en) 2007-03-01 2008-02-29 Nucleic acid detection

Publications (2)

Publication Number Publication Date
CN101680029A CN101680029A (zh) 2010-03-24
CN101680029B true CN101680029B (zh) 2013-09-25

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US (1) US9340832B2 (enExample)
EP (1) EP2129797B8 (enExample)
JP (1) JP5394937B2 (enExample)
CN (1) CN101680029B (enExample)
DK (1) DK2129797T3 (enExample)
ES (1) ES2414286T3 (enExample)
GB (1) GB0703996D0 (enExample)
WO (1) WO2008104794A2 (enExample)

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EP3117011B1 (en) 2014-03-13 2020-05-06 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
CN104677866A (zh) * 2014-03-25 2015-06-03 中国科学院大连化学物理研究所 测定CP装载siRNA体系中siRNA释放的方法
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CN108138221B (zh) * 2015-05-10 2021-11-05 康代思锐公司 用于检测核酸的超高灵敏度探针
CN105274096A (zh) * 2015-09-07 2016-01-27 中国人民解放军第三军医大学第一附属医院 桥式序列区掺入错配碱基的桥式荧光探针及其应用和方法
CN105506082B (zh) * 2015-12-24 2019-04-09 杭州师范大学附属医院 利用链转移型引物扩增核酸及融合探针的方法
CN116064727A (zh) 2016-07-27 2023-05-05 斯坦福大学托管董事会 高度复用荧光成像
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CN107881218B (zh) * 2017-11-23 2021-09-28 中国科学院合肥物质科学研究院 一种用于端粒酶活性检测的球形核酸荧光探针及其制备方法和用途
CN108251502B (zh) * 2017-12-27 2021-12-24 深圳华大基因股份有限公司 一种外周血游离肿瘤dna的富集方法、试剂盒及其应用
CN110240999B (zh) * 2018-03-09 2022-09-06 浙江品级基因科技有限公司 一种提高循环肿瘤dna检出率的检测装置及方法
CN112292460A (zh) 2018-06-12 2021-01-29 主基因有限公司 核酸扩增方法
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US11921049B2 (en) * 2018-11-09 2024-03-05 Shaofeng Ding Pyrophosphorolysis activated fluorescence to measure PAP amplification of nucleic acid
CN109828120B (zh) * 2019-03-12 2021-07-30 南京大学 基于靶标激发金纳米粒子表面dna循环的蛋白质荧光分析方法
JP7621666B2 (ja) * 2019-10-15 2025-01-27 ユニバーシティ オブ フロリダ リサーチ ファウンデーション，インコーポレイティド 血中のアンチトロンビンｉｉｉを定量するためのアプタマーベースのシステム
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Also Published As

Publication number Publication date
GB0703996D0 (en) 2007-04-11
JP5394937B2 (ja) 2014-01-22
JP2010519897A (ja) 2010-06-10
EP2129797A2 (en) 2009-12-09
DK2129797T3 (da) 2013-07-08
US20100227320A1 (en) 2010-09-09
US9340832B2 (en) 2016-05-17
CN101680029A (zh) 2010-03-24
WO2008104794A3 (en) 2008-11-20
EP2129797B1 (en) 2013-04-03
ES2414286T3 (es) 2013-07-18
EP2129797B8 (en) 2013-05-15
WO2008104794A2 (en) 2008-09-04

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Address after: 5th Floor, Building C6, Enterprise Accelerator, No. 11 Kaiyuan Avenue, Huangpu District, Guangzhou City, Guangdong Province

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Patentee before: OXITEC Ltd.

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