DK2129797T3 - Nukleinsyrepåvisning - Google Patents
NukleinsyrepåvisningInfo
- Publication number
- DK2129797T3 DK2129797T3 DK08709576.6T DK08709576T DK2129797T3 DK 2129797 T3 DK2129797 T3 DK 2129797T3 DK 08709576 T DK08709576 T DK 08709576T DK 2129797 T3 DK2129797 T3 DK 2129797T3
- Authority
- DK
- Denmark
- Prior art keywords
- nucleic acid
- acid detection
- detection
- nucleic
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0703996A GB0703996D0 (en) | 2007-03-01 | 2007-03-01 | Nucleic acid detection |
PCT/GB2008/000707 WO2008104794A2 (en) | 2007-03-01 | 2008-02-29 | Nucleic acid detection |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2129797T3 true DK2129797T3 (da) | 2013-07-08 |
Family
ID=37965755
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08709576.6T DK2129797T3 (da) | 2007-03-01 | 2008-02-29 | Nukleinsyrepåvisning |
Country Status (8)
Country | Link |
---|---|
US (1) | US9340832B2 (da) |
EP (1) | EP2129797B8 (da) |
JP (1) | JP5394937B2 (da) |
CN (1) | CN101680029B (da) |
DK (1) | DK2129797T3 (da) |
ES (1) | ES2414286T3 (da) |
GB (1) | GB0703996D0 (da) |
WO (1) | WO2008104794A2 (da) |
Families Citing this family (52)
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EP2071035A1 (en) * | 2007-12-13 | 2009-06-17 | Epigenomics AG | Facilitator and method for amplification |
AU2009223671B2 (en) | 2008-03-11 | 2014-11-27 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
US20100285478A1 (en) | 2009-03-27 | 2010-11-11 | Life Technologies Corporation | Methods, Compositions, and Kits for Detecting Allelic Variants |
US9534255B2 (en) | 2008-12-17 | 2017-01-03 | Life Technologies Corporation | Methods, compositions, and kits for detecting allelic variants |
CN101633957A (zh) * | 2009-06-26 | 2010-01-27 | 北大工学院绍兴技术研究院 | 用于检测小rna的方法及试剂盒 |
ES2577017T3 (es) | 2009-12-22 | 2016-07-12 | Sequenom, Inc. | Procedimientos y kits para identificar la aneuploidia |
JP2013523097A (ja) * | 2010-03-30 | 2013-06-17 | モノクアント・ピーティーワイ・リミテッド | オリゴヌクレオチド機能性を制御する方法 |
CN101871007B (zh) * | 2010-05-07 | 2014-04-30 | 无锡锐奇基因生物科技有限公司 | 用标记探针进行检测和熔解曲线分析的方法 |
ES2605303T3 (es) * | 2010-07-29 | 2017-03-13 | F. Hoffmann-La Roche Ag | Detección cualitativa y cuantitativa de ácidos nucleicos microbianos |
US9353406B2 (en) * | 2010-10-22 | 2016-05-31 | Fluidigm Corporation | Universal probe assay methods |
AU2012249531B2 (en) | 2011-04-29 | 2017-06-29 | Sequenom, Inc. | Quantification of a minority nucleic acid species |
US9796748B2 (en) | 2011-05-02 | 2017-10-24 | President And Fellows Of Harvard College | Spatial sequestration of dynamic nucleic acid circuits |
KR102252447B1 (ko) * | 2011-05-04 | 2021-05-17 | 바이오셉트 인코포레이티드 | 핵산 서열 변이체를 검출하는 방법 |
US9586987B2 (en) | 2011-09-08 | 2017-03-07 | Kabushiki Kaisha Dnaform | Primer set for isothermal amplication of a target nucleic acid sequence |
GB201116131D0 (en) * | 2011-09-19 | 2011-11-02 | Epistem Ltd | Probe |
US20140377762A1 (en) * | 2011-12-19 | 2014-12-25 | 360 Genomics Ltd. | Method for enriching and detection of variant target nucleic acids |
CN102559661B (zh) * | 2012-01-18 | 2014-06-04 | 厦门基科生物科技有限公司 | 一种新型连接酶反应介导的扩增方法及用途 |
WO2013119888A1 (en) | 2012-02-09 | 2013-08-15 | President And Fellows Of Harvard College | Selective nucleic acid amplification from nucleic acid pools |
EP2820129A1 (en) | 2012-03-02 | 2015-01-07 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
CA2878979C (en) | 2012-07-13 | 2021-09-14 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
US9416405B2 (en) * | 2012-11-02 | 2016-08-16 | Life Technologies Corporation | Compositions, methods and kits for enhancing PCR specificity |
US9222122B2 (en) | 2012-11-20 | 2015-12-29 | Src, Inc. | System and method for rapid detection and identification of nucleic acid labeled tags |
US11060145B2 (en) | 2013-03-13 | 2021-07-13 | Sequenom, Inc. | Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus |
GB201310584D0 (en) * | 2013-06-13 | 2013-07-31 | Base4 Innovation Ltd | Droplet storage method |
CA2917627A1 (en) * | 2013-07-18 | 2015-01-22 | President And Fellows Of Harvard College | Specific nucleic acid amplification with compounded selectivity |
CN111100912B (zh) * | 2013-11-26 | 2023-06-30 | 杭州联川基因诊断技术有限公司 | 测定使用的杂交结构 |
EP3117011B1 (en) | 2014-03-13 | 2020-05-06 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
CN104677866A (zh) * | 2014-03-25 | 2015-06-03 | 中国科学院大连化学物理研究所 | 测定CP装载siRNA体系中siRNA释放的方法 |
US9909167B2 (en) | 2014-06-23 | 2018-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | On-slide staining by primer extension |
GB201412316D0 (en) | 2014-07-10 | 2014-08-27 | Momentum Bioscience Ltd | Detecting the absence of micro-organisms |
ES2890776T3 (es) | 2015-03-13 | 2022-01-24 | Life Technologies Corp | Métodos, composiciones y kits para la captura, la detección y la cuantificación del ARN pequeño |
US20180127803A1 (en) * | 2015-05-10 | 2018-05-10 | Quandx Inc. | Ultra sensitive probes for detection of nucleic acid |
US20200087726A1 (en) * | 2015-05-10 | 2020-03-19 | Quandx Inc. | Ultra sensitive probes for detection of nucleic acid |
CN105274096A (zh) * | 2015-09-07 | 2016-01-27 | 中国人民解放军第三军医大学第一附属医院 | 桥式序列区掺入错配碱基的桥式荧光探针及其应用和方法 |
CN105506082B (zh) * | 2015-12-24 | 2019-04-09 | 杭州师范大学附属医院 | 利用链转移型引物扩增核酸及融合探针的方法 |
EP3490616B1 (en) | 2016-07-27 | 2022-09-28 | The Board of Trustees of the Leland Stanford Junior University | Highly-multiplexed fluorescent imaging |
US10081829B1 (en) | 2017-06-13 | 2018-09-25 | Genetics Research, Llc | Detection of targeted sequence regions |
US10947599B2 (en) | 2017-06-13 | 2021-03-16 | Genetics Research, Llc | Tumor mutation burden |
EP3638813A4 (en) * | 2017-06-13 | 2021-06-02 | Genetics Research, LLC, D/B/A ZS Genetics, Inc. | ISOLATION OF TARGET NUCLEIC ACIDS |
US10527608B2 (en) | 2017-06-13 | 2020-01-07 | Genetics Research, Llc | Methods for rare event detection |
CN107881218B (zh) * | 2017-11-23 | 2021-09-28 | 中国科学院合肥物质科学研究院 | 一种用于端粒酶活性检测的球形核酸荧光探针及其制备方法和用途 |
CN108251502B (zh) * | 2017-12-27 | 2021-12-24 | 深圳华大基因股份有限公司 | 一种外周血游离肿瘤dna的富集方法、试剂盒及其应用 |
CN110240999B (zh) * | 2018-03-09 | 2022-09-06 | 浙江品级基因科技有限公司 | 一种提高循环肿瘤dna检出率的检测装置及方法 |
EP3807420A1 (en) | 2018-06-12 | 2021-04-21 | Keygene N.V. | Nucleic acid amplification method |
US11921049B2 (en) * | 2018-11-09 | 2024-03-05 | Shaofeng Ding | Pyrophosphorolysis activated fluorescence to measure PAP amplification of nucleic acid |
CN109828120B (zh) * | 2019-03-12 | 2021-07-30 | 南京大学 | 基于靶标激发金纳米粒子表面dna循环的蛋白质荧光分析方法 |
EP4045682A4 (en) * | 2019-10-15 | 2024-01-17 | Univ Florida | APTAMER-BASED SYSTEM FOR QUANTIFICATION OF ANTITHROMBIN III IN BLOOD |
JP2024506707A (ja) * | 2021-02-16 | 2024-02-14 | バイオフィデリティ・リミテッド | ポリヌクレオチド検出のための方法 |
CN113234803A (zh) * | 2021-06-17 | 2021-08-10 | 上海理工大学 | 一种新型核酸扩增方法 |
Family Cites Families (30)
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FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
GB9211979D0 (en) | 1992-06-05 | 1992-07-15 | Buchard Ole | Uses of nucleic acid analogues |
US6376178B1 (en) * | 1993-09-03 | 2002-04-23 | Duke University | Method of nucleic acid sequencing |
US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
DE69735313T2 (de) | 1996-06-04 | 2006-11-02 | University Of Utah Research Foundation, Salt Lake City | Fluoreszenz-Donor-Akzeptor Paar |
US6248518B1 (en) | 1996-10-29 | 2001-06-19 | Board Of Regents Of University Of Nebraska | Method for detecting point mutations in DNA utilizing fluorescence energy transfer |
US5849497A (en) | 1997-04-03 | 1998-12-15 | The Research Foundation Of State University Of New York | Specific inhibition of the polymerase chain reaction using a non-extendable oligonucleotide blocker |
FR2779154B1 (fr) | 1998-05-27 | 2002-07-12 | Bio Merieux | Procede d'amplification d'au moins une sequence nucleotidique particuliere et amorces de mise en oeuvre |
GB9811415D0 (en) | 1998-05-28 | 1998-07-22 | Dedar Limited | Gasifiers |
GB9902971D0 (en) * | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Assay |
ATE501269T1 (de) | 1999-03-18 | 2011-03-15 | Exiqon As | Detektion von genmutationen mittels lna primer |
US20020025519A1 (en) | 1999-06-17 | 2002-02-28 | David J. Wright | Methods and oligonucleotides for detecting nucleic acid sequence variations |
JP2003517309A (ja) | 1999-12-02 | 2003-05-27 | ディーエヌエー サイエンシーズ インコーポレーテッド | 単一ヌクレオチドの変異及びジェノタイピングの決定方法 |
JP3638516B2 (ja) | 2000-09-28 | 2005-04-13 | 株式会社日立製作所 | 核酸検出方法および核酸検出キット |
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EP1430150B1 (en) | 2001-09-24 | 2015-08-19 | One Lambda, Inc. | Diagnostic probe detection system |
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US20030211483A1 (en) | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
US20040091905A1 (en) | 2002-07-01 | 2004-05-13 | Baochuan Guo | Method for detecting mutated polynucleotides within a large population of wild-type polynucleotides |
WO2004018626A2 (en) * | 2002-08-21 | 2004-03-04 | Epoch Biosciences, Inc. | Abasic site endonuclease assay |
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WO2004065628A1 (en) | 2003-01-21 | 2004-08-05 | Guoliang Fu | Quantitative multiplex detection of nucleic acids |
CA2516299A1 (en) | 2003-02-18 | 2004-09-02 | Applera Corporation | Compositions and methods for multiplex analysis of polynucleotides |
WO2005038039A2 (en) * | 2003-10-13 | 2005-04-28 | Genaco Biomedical Products, Inc. | Method for multiplex primer based amplification of nucleic acids |
US20060183136A1 (en) | 2004-11-05 | 2006-08-17 | Genevieve Pont-Kingdon | Method for haplotyping and genotyping by melting curve analysis of hybridization probes |
WO2007008997A2 (en) | 2005-07-12 | 2007-01-18 | The Board Of Trustees Of The Leland Stanford Junior University | Template specific inhibition of pcr |
WO2007045890A1 (en) | 2005-10-21 | 2007-04-26 | Primerdesign Ltd | Probe |
US20100009355A1 (en) | 2006-03-14 | 2010-01-14 | Kolodney Michael S | Selective amplification of minority mutations using primer blocking high-affinity oligonucleotides |
GB0703997D0 (en) * | 2007-03-01 | 2007-04-11 | Oxitec Ltd | Methods for detecting nucleic sequences |
-
2007
- 2007-03-01 GB GB0703996A patent/GB0703996D0/en not_active Ceased
-
2008
- 2008-02-29 US US12/529,204 patent/US9340832B2/en active Active
- 2008-02-29 ES ES08709576T patent/ES2414286T3/es active Active
- 2008-02-29 WO PCT/GB2008/000707 patent/WO2008104794A2/en active Application Filing
- 2008-02-29 DK DK08709576.6T patent/DK2129797T3/da active
- 2008-02-29 CN CN200880012820.5A patent/CN101680029B/zh active Active
- 2008-02-29 JP JP2009551271A patent/JP5394937B2/ja not_active Expired - Fee Related
- 2008-02-29 EP EP08709576.6A patent/EP2129797B8/en not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
GB0703996D0 (en) | 2007-04-11 |
JP2010519897A (ja) | 2010-06-10 |
CN101680029A (zh) | 2010-03-24 |
EP2129797B8 (en) | 2013-05-15 |
EP2129797B1 (en) | 2013-04-03 |
EP2129797A2 (en) | 2009-12-09 |
ES2414286T3 (es) | 2013-07-18 |
WO2008104794A2 (en) | 2008-09-04 |
US20100227320A1 (en) | 2010-09-09 |
WO2008104794A3 (en) | 2008-11-20 |
CN101680029B (zh) | 2013-09-25 |
JP5394937B2 (ja) | 2014-01-22 |
US9340832B2 (en) | 2016-05-17 |
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