CN101653486A - Compound Bailongsan for treating diarrhoea of nursery pig and preparation method thereof - Google Patents
Compound Bailongsan for treating diarrhoea of nursery pig and preparation method thereof Download PDFInfo
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- CN101653486A CN101653486A CN200910306303A CN200910306303A CN101653486A CN 101653486 A CN101653486 A CN 101653486A CN 200910306303 A CN200910306303 A CN 200910306303A CN 200910306303 A CN200910306303 A CN 200910306303A CN 101653486 A CN101653486 A CN 101653486A
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- oxytetracycline
- metronidazole
- nursery pig
- bailongsan
- sow
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Abstract
The invention discloses a compound Bailongsan for treating diarrhoea of nursery pig and a preparation method thereof, and aims at providing a safe, convenient, effective and high-efficiency compound Bailongsan for treating diarrhoea of nursery pig and a preparation method thereof with simple-process and easy-implementation. The simple-process and easy-implementati comprises the following components by weight: 20-40% of gentian, 5-15% of coptis, 1-10% of oxytetracycline, 1-10% of metronidazole and the balance of pulsatilla. The Bailongsan is combined with the traditional Chinese medicines and the Western medicines to be taken by sow from which the milk is used for treating diarrhoea of nursery pig. The traditional Chinese medicines, such as the pulsatilla, the gentian and the coptis, have the functions of clearing heat and drying dampness and removing heat from the blood and relieving diarrhea; and oxytetracycline and metronidazole have the antimicrobial function, therefore the combination above has the functions of increasing antimicrobial spectrum, reducing drug resistance of bacteria, and treating the nursery pig by the components of the traditional Chinese medicines and the Western medicines through milk, and is characterized by safe pharmaceutical composition and unremarkable side effect to sow, thereby preventing the bacterial infection and reducing the rate of the bacterial infection to the sow and the nursery pig.
Description
Technical field
The present invention relates to the white dragon of a kind of suckling porcine compound looses and preparation method thereof.
Background technology
Suckling pig diarrhoea is a kind of commonly encountered diseases, and this kind disease mainly occurs in piglet between age of sucking.Cause that this sick main cause is a bacterial infection, mainly contain that escherichia coli, Salmonella and anaerobe etc. cause.
This kind disease does not also have good Therapeutic Method now.Because after piglet is suffered from diarrhoea, weak, cause stress easily, the method of taking to inject causes piglet to faint from fear, suffer a shock easily even causes death, and other conventional methods are because special physiological stage of suckling pig, and can not realize, thereby in breeding process, cause piglet that very big mortality rate is arranged, bring very big puzzlement to the culturist.
Summary of the invention
The present invention is in order to overcome weak point of the prior art, provides a kind of and can treat suckling pig diarrhoea, and instant effect, safe in utilization, the white dragon of compound recipe looses easily.
It is simple that another object of the present invention provides a kind of technology, the preparation method that the white dragon of the compound recipe that the easy above-mentioned suckling pig of realizing is used looses.
The present invention is achieved through the following technical solutions:
A kind ofly be used for the treatment of the white dragon of suckling pig diarrheal compound recipe and loose, it is characterized in that, form by following raw material by weight percentage: Radix Gentianae 20~40%, Rhizoma Coptidis 5~15%, oxytetracycline 1~10%, metronidazole 1~10%, the Radix Pulsatillae of surplus.
A kind of above-mentioned preparation method that the white dragon of suckling pig diarrheal compound recipe looses that is used for the treatment of, it is characterized in that, comprise the steps: Radix Gentianae, Rhizoma Coptidis, Radix Pulsatillae pulverize separately are sieved back the mixing, in batch mixer, fully mixed 1 hour with oxytetracycline first, nitre azoles again, promptly get white imperial the loosing of suckling pig diarrheal compound recipe that be used for the treatment of of the present invention, form by following raw material by weight percentage in this powder: Radix Gentianae 20~40%, Rhizoma Coptidis 5~15%, oxytetracycline 1~10%, metronidazole 1~10%, the Radix Pulsatillae of surplus.
Wherein preferable consisting of: Radix Gentianae 25~35% by weight percentage, Rhizoma Coptidis 8~12%, oxytetracycline 4~7%, metronidazole 4~7%, the Radix Pulsatillae of surplus.
Best group becomes: Radix Gentianae 27% by weight percentage, Rhizoma Coptidis 9%, oxytetracycline 5%, metronidazole 5%, the Radix Pulsatillae 54%.
The present invention has following technique effect:
The white dragon of suckling porcine compound of the present invention looses Chinese medicine and western medicine is combined, and searches for food by sow, feeds piglet by milk again and treats piglet diarrhea.The present invention remedies Chinese medicine and western medicine shortcoming separately, again the powder of developing at advantage separately.Chinese medicines such as the Radix Pulsatillae, Radix Gentianae, Rhizoma Coptidis have the function of heat clearing and damp drying, eliminating pathogenic heat from blood to cure dysentery, oxytetracycline, metronidazole have antibacterial functions, combine and have the increase antimicrobial spectrum, reduce the problem of bacterial drug resistance, and the Chinese medicine and western medicine composition can both enter in the milk, suckling pig reaches therapeutic effect by the milk of searching for food, and drug regimen safety, take non-evident effect to sow, and can prevent bacterial infection, reduce the probability of sow, piglet bacterial infection, treatment suckling pig diarrhoea instant effect, safe in utilization, convenient.
The specific embodiment
Below in conjunction with specific embodiment to the detailed description of the invention.
Embodiment 1
Getting Radix Gentianae 20kg, Rhizoma Coptidis 15kg, Radix Pulsatillae 54kg pulverized No. 2 sieve backs and oxytetracycline 10kg, metronidazole 1kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Embodiment 2
Getting Radix Gentianae 40kg, Rhizoma Coptidis 5kg, Radix Pulsatillae 44kg pulverized No. 2 sieve backs and oxytetracycline 1kg, metronidazole 10kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Embodiment 3
Getting Radix Gentianae 25kg, Rhizoma Coptidis 8kg, Radix Pulsatillae 56kg pulverized No. 2 sieve backs and oxytetracycline 4kg, metronidazole 7kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Embodiment 4
Getting Radix Gentianae 35kg, Rhizoma Coptidis 12kg, Radix Pulsatillae 42kg pulverized No. 2 sieve backs and oxytetracycline 7kg, metronidazole 4kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Embodiment 5
Getting Radix Gentianae 30kg, Rhizoma Coptidis 10kg, Radix Pulsatillae 50kg pulverized No. 2 sieve backs and oxytetracycline 5.5kg, metronidazole 4.5kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Embodiment 6
Getting Radix Gentianae 27kg, Rhizoma Coptidis 9kg, Radix Pulsatillae 54kg pulverized No. 2 sieve backs and oxytetracycline 5kg, metronidazole 5kg and mixed in batch mixer that promptly get suckling porcine compound of the present invention in 1 hour imperial in vain diffusing.
Clinical trial:
1. laboratory animal:
Picked at random is 100 of the sows of suckling pig in spite of illness, every sow band piglet 8-10 head.
2. experiment medicine:
The development of the diffusing our unit of the white dragon of the suckling porcine compound of the embodiment of the invention 6 preparations;
Radix Gentianae, Rhizoma Coptidis, the Radix Pulsatillae are pressed the diffusing our unit of the white dragon prepared in laboratory of 3: 1: 6 proportional arrangement;
Complex (carrier is a glucose) the our unit's prepared in laboratory that contains oxytetracycline 5g and metronidazole 5g by 100g.
3. experimental technique:
100 sows are divided into four groups at random by the band son, 25 every group, young 9 of wherein average every headband.
The A group does not give Drug therapy for the blank group.
The B group is treated usage with Radix Gentianae, Rhizoma Coptidis, the Radix Pulsatillae by the white dragon of 3: 1: 6 proportional arrangement is diffusing: for oral administration, and every sow 50g, 1 time on the one, logotype 3 days.Feed piglet with the milk of sow every day.
C organizes the complex that contains oxytetracycline 5g and metronidazole 5g with 100g, usage: for oral administration, and every sow 50g, 2 times on the one, logotype 3 days.Feed piglet with the milk of sow every day.
The D group is treated usage with the white dragon of compound recipe of the embodiment of the invention 6 preparations is diffusing: for oral administration, and every sow 50g, 1 time on the one, logotype 3 days.Feed piglet with the milk of sow every day.
After the treatment beginning, write down ill piglet health situation of change every day and distribute, treat and add up therapeutic effect after 5 days, wherein:
Invalid: as after referring to 5 days, to suffer from the pig symptom and do not have obvious change, still keep the preceding symptom of treatment.
Effectively: after referring to 5 days, suffer from the pig symptom and change, the effect before symptom is better than treating.
Cure: after referring to 5 days, transference cure is suffered from pig and is got well.Its numeral is included in the significant digits.
Symptom is arranged during end: after referring to 5 days, suffer from pig and still have certain symptom, its symptom performance is better than before the treatment or does not have change, suffers from pig and does not cure.Its numeral has been included in the numeral of invalid number and effective number.
Result of the test is as shown in table 1.In use, the medicine side reaction does not appear in sow.
4. conclusion:
Analyze by statistics from the result of the test of table 1, the imperial in vain treatment group of loosing of the compound recipe of the embodiment of the invention 6, oxytetracycline complex treatment group and the diffusing treatment group of white dragon and matched group difference ultimate ratio are.Curative effect of the present invention is better than other two kinds of medicines.
Table 1
Numbering | Group | Invalid number | Effective number | Cure a number | A symptom number is arranged during end | A dead number |
??A | Matched group | ??225 | ??0 | ??0 | ??72 | ??153 |
??B | Bai Long looses | ??100 | ??125 | ??93 | ??64 | ??68 |
??C | The oxytetracycline complex | ??95 | ??130 | ??83 | ??81 | ??61 |
??D | The diffusing orally taken for curing of the white dragon of the compound recipe of embodiment 6 | ??28 | ??197 | ??181 | ??32 | ??12 |
Claims (4)
1. one kind is used for the treatment of white imperial the loosing of suckling pig diarrheal compound recipe, it is characterized in that, is made up of following raw material by weight percentage: Radix Gentianae 20~40%, Rhizoma Coptidis 5~15%, oxytetracycline 1~10%, metronidazole 1~10%, the Radix Pulsatillae of surplus.
2. according to claim 1ly be used for the treatment of the white dragon of suckling pig diarrheal compound recipe and loose, it is characterized in that, form by following raw material by weight percentage: Radix Gentianae 25~35%, Rhizoma Coptidis 8~12%, oxytetracycline 4~7%, metronidazole 4~7%, the Radix Pulsatillae of surplus.
3. according to claim 1ly be used for the treatment of the white dragon of suckling pig diarrheal compound recipe and loose, it is characterized in that, form by following raw material by weight percentage: Radix Gentianae 27%, Rhizoma Coptidis 9%, oxytetracycline 5%, metronidazole 5%, the Radix Pulsatillae 54%.
4. a claim 1 is described is used for the treatment of the white dragon of suckling pig diarrheal compound recipe and looses, it is characterized in that, comprise the steps: Radix Gentianae, Rhizoma Coptidis, Radix Pulsatillae pulverize separately are sieved, fully mixed 1 hour with oxytetracycline, metronidazole again, promptly get white imperial the loosing of suckling pig diarrheal compound recipe that be used for the treatment of of the present invention, form by following raw material by weight percentage in this powder: Radix Gentianae 20~40%, Rhizoma Coptidis 5~15%, oxytetracycline 1~10%, metronidazole 1~10%, the Radix Pulsatillae of surplus.
Priority Applications (1)
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CN200910306303A CN101653486A (en) | 2009-08-28 | 2009-08-28 | Compound Bailongsan for treating diarrhoea of nursery pig and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102416050A (en) * | 2011-11-25 | 2012-04-18 | 河北康利动物药业有限公司 | Veterinary medicinal preparation for treating colibacillosis and preparation method thereof |
CN105412144A (en) * | 2015-11-23 | 2016-03-23 | 广西南宁劲能农业科技有限公司 | Drug for treating piglet diarrhea and using method |
-
2009
- 2009-08-28 CN CN200910306303A patent/CN101653486A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102416050A (en) * | 2011-11-25 | 2012-04-18 | 河北康利动物药业有限公司 | Veterinary medicinal preparation for treating colibacillosis and preparation method thereof |
CN102416050B (en) * | 2011-11-25 | 2013-11-27 | 河北康利动物药业有限公司 | Veterinary medicinal preparation for treating colibacillosis and preparation method thereof |
CN105412144A (en) * | 2015-11-23 | 2016-03-23 | 广西南宁劲能农业科技有限公司 | Drug for treating piglet diarrhea and using method |
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Application publication date: 20100224 |