CN101653474B

CN101653474B - Medicine for treating hemorrhoid and its preparing process

Info

Publication number: CN101653474B
Application number: CN2009103071173A
Authority: CN
Inventors: 刘承彪
Original assignee: Individual
Current assignee: Individual
Priority date: 2009-09-17
Filing date: 2009-09-17
Publication date: 2011-04-06
Anticipated expiration: 2029-09-17
Also published as: CN101653474A

Abstract

The invention relates to a medicine for treating hemorrhoid and its preparing process. The medicine comprises 20-50 parts by weight of Folium Artemisiae Argyi, 20-40 parts by weight of Chinese honeylocust spine, 15-45 parts by weight of sophora flower, 15-50 parts by weight of glossy ganoderma and 0.2-1 part by weight of 60 vol% of liquor . The medicine for treating hemorrhoid has advantages of safety, short treatment course, high yield, and low cost.

Description

The medicine and the preparation method that are used for the treatment of hemorrhoid

Technical field

The present invention relates to a kind of injection, particularly a kind of medicine and preparation method that is used for the treatment of hemorrhoid.

Background technology

Hemorrhoid are human distinctive commonly encountered diseases, frequently-occurring disease.Show that according to relevant reconnaissance information the sickness rate of anorectal disease is 59.1%, hemorrhoid account for 87.25% in all anal and intestinal diseases, and wherein common with internal hemorrhoid, account for 52.19% of all anal and intestinal diseases.The men and women all can fall ill, and women's sickness rate is 67%, and male's sickness rate is 53.9%; Any age all can fall ill, and wherein the people in 20-40 year comparatively more sees, and increases the weight of with advancing age and gradually, so saying of the fat Krupp of Gui department arranged.

Medical science indication hemorrhoid comprise internal hemorrhoid, external hemorrhoid, mixed hemorrhoid, are the venous plexus generation varicose of anal orifice and rectal intestine bottom and anal mucosa and a kind of chronic disease of the one or more softish vein group that forms.If suffer from hemorrhoid, the wall of vein of anal enlargement distortion will become very thin, so very easily breaks during defecation.Internal hemorrhoid is long hemorrhoid at the anus catheter section start, if expansible vein is positioned at more below, almost is on the anal canal mouth, and the vein of this varicose just is external hemorrhoid.No matter thrombosis all may take place in internal hemorrhoid or external hemorrhoid.When thrombosis takes place, the blood clotting in bulk in the hemorrhoid, thus cause pain.

Tradition hemorrhoid treating method has operative therapy, oral medicine, medicine for external use and pastes medication, ligation, cover bundle therapy etc., wherein: though the advantage that the traditional operation therapy produces effect, but there are postoperative pain and long being in hospital and problem such as healing time, and there is certain recurrence probability in the traditional operation therapy, the particularly important is it and excised the anus pad more or less, thereby have patient to have incontinence phenomenon in various degree to take place after surgery; Oral medicine, medicine for external use and subsides medicine expectant treatment can improve symptom, and it is slow not only to take effect, and is difficult to eliminate focus, not thorough, and long-term prescription cost height has side effect to health; Ligation, cover are pricked therapy can make the podex blood circulation be obstructed, and easily produces congestion edema, pain, difficult defecation etc.

Summary of the invention

The purpose of this invention is to provide a kind of medicine and preparation method that is used for the treatment of hemorrhoid.Described medicine is used for the treatment of hemorrhoid and has safety, short treating period, cure rate height, the advantage that cost is low.

Technical scheme of the present invention is the medicine that is used for the treatment of hemorrhoid, comprises Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum and Chinese liquor, and the weight portion of its each component is:

20～50 parts of Folium Artemisiae Argyis;

20～40 parts of Spina Gleditsiaes;

15～45 parts in Flos Sophorae;

15～50 parts of Ganoderma lucidum seu Japonicumes;

0.2～1 part of 60 ° of Chinese liquor.

Optimized technical scheme of the present invention is the described medicine that is used for the treatment of hemorrhoid, comprises Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum and Chinese liquor, and the weight portion of its each component is:

20 parts of Folium Artemisiae Argyis;

20 parts of Spina Gleditsiaes;

15 parts in Flos Sophorae;

15 parts of Ganoderma lucidum seu Japonicumes;

0.3～0.4 part of 60 ° of Chinese liquor.

Be used for the treatment of the preparation method of the medicine of hemorrhoid, following steps arranged:

1) gets Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum according to above-mentioned dosage, clean 1～2 time with clear water;

2) add 2000～5000 parts in water, after boiling, intense fire boiled 50～120 minutes;

3) filter, obtain medicinal liquid, add 60 ° of Chinese liquor of above-mentioned dosage after the medicinal liquid cooling, promptly get the medicine that is used for the treatment of hemorrhoid of the present invention.

Described water is distilled water.

Ganoderma lucidum seu Japonicum of the present invention (calling Ganoderma in the following text) nature and flavor are sweet flat.The pharmaceutical component of Ganoderma is very abundant, wherein active ingredient can be divided into ten big classes, comprise ganoderan, Ganoderma polypeptide, triterpenes, 16 seed amino acids (wherein containing seven kinds of essential amino acids), protein, steroid class, mannitol, coumarin glycosides, alkaloid, organic acid (the main Fumaric acid that contains), and trace element Ge, P, Fe, Ca, Mn, Zn, etc.Ganoderma has dual regulation to human body, and the kind of curing the disease relates to each systems such as cardiovascular and cerebrovascular vessel, digestion, nerve, endocrine, breathing, motion, and is especially very remarkable to the preventive and therapeutic effect of tumor, hepatic lesions, insomnia and aging.The range of application of Ganoderma is very extensive.See with regard to differential diagnosis in tcm, because this product goes into the five internal organs kidney tonification whole body QI of five ZANG-organs, so no matter a little less than the heart, lung, the liver,spleen,kidney deficiency of five ZANG-organs, all can obey it.Ganoderma is cured the disease to plant and relates to each systems such as breathing, circulation, digestion, nerve, endocrine and motion; Contain inside and outside, woman, youngster, each section's disease of face.Its basic reason just is that Ganoderma has strengthening the body resistance, raise immunity, the huge effect that improves Abwehrkraft des Koepers.

Folium Artemisiae Argyi has the blood of regulating the flow of vital energy, by cold-damp; Warming the meridian, hemostasis, antiabortive.Main moxibustion all kinds of diseases and ailments.Control trusted subordinate's cold type of pain, the convulsion of having loose bowels, chronic dysentery is told nosebleed, hematochezia, menoxenia, metrorrhagia, leukorrhagia, frequent fetal movement, carbuncle and ulcer, scabies.

Flos Sophorae taste delicate fragrance sweetness is rich in vitamin and several mineral materials, also has the effect of heat-clearing and toxic substances removing, removing heat from blood lung moistening, blood pressure lowering, prevention of stroke simultaneously.

Spina Gleditsiae phytomorph deciduous tree, Spina jujubae is cylindrical, normal branch.Winglike compound leaf clusters mutually, and lobule 6～16 is avette to long avette, long 3～8cm, and wide 1～2cm, the tip point, the base portion wedge shape, there is serration at the edge.The raceme axil is given birth to and give birth on the top, the flower polygamy; Calyx 4 splits; Petal 4, faint yellow; Stamen 6～8; Ovary is along the suture hairiness.Pod prolate strip, long 12～35cm, wide 2～4cm, purple brown is sometimes by the white wax powder.May at florescence, really October phase.Nature and flavor, warm in nature, acrid in the mouth.The function poison holding that cures mainly, subsides a swelling, evacuation of pus, parasite killing.Be used for carbuncle from the beginning of or pusization do not burst; External treatment scabies leprosy.

Anticorrosion, weak anesthesia that Chinese liquor has, can be anticorrosion, the effect of topical pain relief.

The present invention has advantage safe in utilization for the medicine of the treatment hemorrhoid of employing pure natural plant preparation.The present invention adopts the said method configuration, is used to make injection, has the powerful hardened effect of antiinflammatory clearing away summer-heat, dispersing swelling and dissipating binds, promoting blood circulation and hemostasis.Medicine sterilization antibacterial action wide spectrum of the present invention, the medication number of times is few, and its curative effect obviously is better than present similar medicine, is particularly useful for the treatment of internal hemorrhoid, and cure rate reaches 98%.Adopt Drug therapy hemorrhoid of the present invention, only need injection 1-3 time, 1 to 3 day treatment time can finish, and therefore also had treatment time short, and patient's medication spends low, the advantage that health is had no side effect.

The unit of weight portion of the present invention can adopt milligram, gram, kilogram etc.

The specific embodiment

Embodiment 1

Get Folium Artemisiae Argyi 20 grams, Spina Gleditsiae 20 grams, Flos Sophorae 15 grams, Ganoderma lucidum seu Japonicum 15 grams clean 1～2 time with clear water; Add water 2000 grams, boil the back intense fire and boiled 50～60 minutes, liquid is the tea yellow; Filter, obtain medicinal liquid, add 60 ° of Chinese liquor, 0.2～1 gram after the medicinal liquid cooling, promptly get the medicine that is used for the treatment of hemorrhoid of the present invention.

Embodiment 2

Get Folium Artemisiae Argyi 50 grams, Spina Gleditsiae 40 grams, Flos Sophorae 45 grams, Ganoderma lucidum seu Japonicum 50 grams clean 1～2 time with clear water; Add water 5000 grams, boil the back intense fire and boil about 120 minutes, liquid is the tea yellow; Filter, obtain medicinal liquid, add 60 ° of Chinese liquor, 0.2～1 gram after the medicinal liquid cooling, promptly get the medicine that is used for the treatment of hemorrhoid of the present invention.

Embodiment 3

Get Folium Artemisiae Argyi 35 grams, Spina Gleditsiae 30 grams, Flos Sophorae 30 grams, Ganoderma lucidum seu Japonicum 30 grams clean 1～2 time with clear water; Add water 3000 grams, boil the back intense fire and boil about 100 minutes, liquid is the tea yellow; Filter, obtain medicinal liquid, add 60 ° of Chinese liquor, 0.2～1 gram after the medicinal liquid cooling, promptly get the medicine that is used for the treatment of hemorrhoid of the present invention.

One. bacteriostatic experiment:

Experimental technique

1. the extraction of medicine: get 100～200 milliliters of the described medicines that is used for the treatment of hemorrhoid of embodiment 1-3;

2. strain is chosen:

(1) the yellow glucose fungus of standard gold

Antibacterial circle diameter with Oxford agar diffusion method analytical unit penicillin is 10mm, and with 0.5,1.0,2.0 units present curve clocklike;

(2) dysentery bacterium is used F2a;

(3) escherichia coli are isolated by clinical, uncertain sex;

(4) bacillus pyocyaneus is isolated by clinical;

(5) pneumobacillus is isolated by clinical, does not all have drug resistance, the bacterium colony typical case, and thalline is complete consistent, does not have variation or degeneration form, all can be even muddiness in meat soup, no solids precipitation person.Time spent plants in the meat soup base earlier by preserving the bacterial strain pipe, cultivates about 18 hours, and subcultivation meat soup is two, three times again, cultivates at last 8 hours, washes dish and has.

3. the preparation of culture medium:

The steamed beef soup base is to add 1% peptone in meat soup, 0.5% Sal.Bouillon agar is to add 1% agar in described steamed beef soup base, and its pH value is 7.4～7.6.When using the culture medium of new system instead, new culture medium and old culture medium are done balance test, in contrast, and in the hope of antibacterial unanimity as a result.

4. the scraps of paper:

With diameter 0.5cm circular filter paper, soak the medicine (liquid) that is used for the treatment of hemorrhoid and be put in the plate.

5. the result observes

Cultivate after 8 hours beginning observed and recorded result about 37 ℃.Obvious inhibition zone is arranged, the above person of diameter 10mm, promptly assert has bacteriostasis.

Bacteriostatic test sees the following form:

The strain name	Sterilization circle (diameter)	Inhibition zone (diameter)
			The hemolytic staphylococcus aureus	29mm	31mm
Escherichia coli	27mm	36mm
			Bacillus pyocyaneus	26mm	37mm

Dysentery bacterium	30mm	38mm
			Pneumobacillus	28mm	30mm

The result: Xenorhabdus is all produced bactericidal action, and fungistatic effect is good.

Two. clinical effectiveness

During use, get 3～3.8 milliliters of said medicine, adding distil water is diluted to 4 milliliters, promptly is made into injectable drug, during treatment with the root of injection direct injection in hemorrhoid.

The applicant is through the clinical trial of nearly 1000 examples, wherein, the patient has the men and women respectively, the crowd of age from the child to all age groups such as old men, and the state of an illness comprises that internal hemorrhoid reaches the 1-5 centimetre, not outstanding, give prominence to, one, a plurality ofly various cases such as be distributed in around the anus, adopt medicine of the present invention to inject, all cure.Cure and followed up a case by regular visits in back 6 months to 2 years, all do not have recurrence, and have no adverse reaction and toxicity.

Claims

1. a medicine that is used for the treatment of hemorrhoid is characterized in that comprising Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum and Chinese liquor, and the weight portion of its each component is:

20～50 parts of Folium Artemisiae Argyis;

20～40 parts of Spina Gleditsiaes;

15～45 parts in Flos Sophorae;

15～50 parts of Ganoderma lucidum seu Japonicumes;

0.2～1 part of 60 ° of Chinese liquor.

2. the medicine that is used for the treatment of hemorrhoid according to claim 1 is characterized in that comprising Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum and Chinese liquor, and the weight portion of its each component is:

20 parts of Folium Artemisiae Argyis;

20 parts of Spina Gleditsiaes;

15 parts in Flos Sophorae;

15 parts of Ganoderma lucidum seu Japonicumes;

0.3～0.4 part of 60 ° of Chinese liquor.

3. prepare claim 1 or the 2 described methods that are used for the treatment of the medicine of hemorrhoid, it is characterized in that following steps are arranged:

1) gets Folium Artemisiae Argyi, Spina Gleditsiae, Flos Sophorae, Ganoderma lucidum seu Japonicum according to claim 1 or 2 described dosage, clean 1～2 time with clear water;

2) add 2000～5000 parts in water, boil the back intense fire and boiled 50～120 minutes;

3) filter, obtain medicinal liquid, medicinal liquid cooling rear weight profit requires 60 ° of Chinese liquor of 1 or 2 described dosage, promptly gets the medicine that is used for the treatment of hemorrhoid of the present invention.

4. method according to claim 3 is characterized in that: described water is distilled water.