CN103191291A - Traditional Chinese medicine composition for treating viral myocarditis - Google Patents

Traditional Chinese medicine composition for treating viral myocarditis Download PDF

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CN103191291A
CN103191291A CN2013101436210A CN201310143621A CN103191291A CN 103191291 A CN103191291 A CN 103191291A CN 2013101436210 A CN2013101436210 A CN 2013101436210A CN 201310143621 A CN201310143621 A CN 201310143621A CN 103191291 A CN103191291 A CN 103191291A
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radix
rhizoma
grass
chinese medicine
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CN103191291B (en
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王金磊
吕军荣
马世爱
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王金磊
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Abstract

The invention provides a traditional Chinese medicine composition for treating viral myocarditis. The composition is prepared from daphne koreana nakai, purple flower holly leaf, liquorice, lily, evening primrose of safflower, giant knotweed rhizome, baical skullcap root, rhizome of medical angiopteris, snake slough, paniculate swallowwort root, olive, dangshen, glossy privet fruit, lagochilus lanatonodus, rhizoma corydalis and long pepper. The composition can be clinically used for treating viral myocarditis.

Description

A kind of Chinese medicine composition for the treatment of viral myocarditis
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of viral myocarditis.
Background technology
Viral myocarditis refers to the acute or chronic myocarditis disease that caused by various viruses, and is in the majority with child and the adult below 40 years old.Wherein, 35% patient falls ill between 10-30 year, and adult's age of onset is many in 31-35 year.Patient about 90% is chief complaint with arrhythmia or head sees symptom, common cardiopalmus, uncomfortable in chest, pareordia dull pain, dizziness, symptom such as weak, can occur fainting even this syndrome of Ah one, serious symptom diffusivity myocarditis can cause acute heart failure, easily merges cardiogenic shock or causes cardiomyopathy.Because Pathogenesis of Viral Myocarditis still imperfectly understands, therefore, doctor trained in Western medicine does not still have the specific treatment method at present, the clinical symptomatic treatments such as immunosuppressant, interferon and myocardial cell nutrient that adopt more, and the life-time service effect is bad.Draw through inventor's long-term practice, the Chinese medicine viral myocarditis of curing the disease has better effect, obtains good effect.
Summary of the invention
The Chinese medicine composition of the treatment viral myocarditis that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt Radix Cochleariae officinalis grass, Ilex purpurea Hassk.[I.chinensis Sims, Radix Glycyrrhizae, Bulbus Lilii, oenothera rosea L' Her. Ex Aif, Rhizoma Polygoni Cuspidati, Radix Scutellariae, Rhizoma Angiopteridis Officinalis, Periostracum Serpentis, Radix Cynanchi Paniculati, olive, Radix Codonopsis, Fructus Ligustri Lucidi, chaetomers cleftlip grass, Rhizoma Corydalis, Piper longum according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention and make Radix Cochleariae officinalis grass 30-50 part, Ilex purpurea Hassk.[I.chinensis Sims 25-40 part, Radix Glycyrrhizae 25-40 part, Bulbus Lilii 25-40 part, oenothera rosea L' Her. Ex Aif 20-30 part, Rhizoma Polygoni Cuspidati 20-30 part, Radix Scutellariae 20-30 part, Rhizoma Angiopteridis Officinalis 20-30 part, Periostracum Serpentis 10-20 part, Radix Cynanchi Paniculati 10-20 part, olive 10-20 part, Radix Codonopsis 10-20 part, Fructus Ligustri Lucidi 10-20 part, chaetomers cleftlip grass 10-20 part, Rhizoma Corydalis 10-15 part, Piper longum 1-5 part by following raw material medicaments.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of Radix Cochleariae officinalis grass, 35 parts of Ilex purpurea Hassk.[I.chinensis Sims, 35 parts in Radix Glycyrrhizae, 30 parts of Bulbus Liliies, 25 parts of oenothera rosea L' Her. Ex Aif, 25 parts of Rhizoma Polygoni Cuspidati, 22 parts of Radix Scutellariaes, 22 parts of Rhizoma Angiopteridis Officinaliss, 16 parts of Periostracum Serpentiss, 16 parts of Radix Cynanchi Paniculatis, 16 parts of olives, 16 parts of Radix Codonopsis, 15 parts of Fructus Ligustri Lucidi, 15 parts of chaetomers cleftlip grass, 12 parts of Rhizoma Corydalis, 3 parts of Piper longums.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Cochleariae officinalis grass: hot, warm.Promoting the flow of QI-blood by warming the meridian, promoting blood circulation and stopping pain.Be used for coronary heart disease, angina pectoris, thromboangiitis obliterans, arthritis, diseases such as chilblain.
Ilex purpurea Hassk.[I.chinensis Sims: bitter, puckery, cool.Heat-clearing and toxic substances removing, promoting tissue regeneration and ulcer healing, promoting blood circulation and hemostasis.Be used for the cough due to lung-heat, laryngopharynx swelling and pain, dysentery,
Diarrhoea, biliary tract infection, urinary tract infection, angina pectoris, burn and scald, the pyretic toxicity carbuncle, ulcer of the lower limb, leprelcosis, eczema, chilblain is chapped, thromboangiitis obliterans, diseases such as traumatic hemorrhage.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, relieving spasm to stop pain, the mediation property of medicine.Be used for abundant expectoration cough, pathopyretic ulcer.
Bulbus Lilii: sweet, little hardship is slightly cold GUIXIN, lung meridian.Nourishing YIN to relieve dryness, clearing away heart-fire for tranquillization.Cure mainly the fidgets due to deficiency palpitation with fear due to unsuccessful of deficiency of YIN chronic cough or feelings will, insomnia and dreamful sleep.
Oenothera rosea L' Her. Ex Aif: bitter, cool.Detoxifcation, blood stasis dispelling.Be used for hot carbuncle toxin, coronary heart disease, diseases such as hypertension.
Rhizoma Polygoni Cuspidati: bitter, cold.Return liver, gallbladder, lung meridian.Promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, expelling phlegm for arresting cough.Be used for jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, carbuncle sore tumefacting virus, venom, cough due to lung-heat etc.
Radix Scutellariae: bitter, cold, attach to the lung and stomach meridians.Heat clearing and damp drying, eliminating fire and detoxication.Outer be used for carbuncle sore tumefacting virus, damp and hot painful abdominal mass is vexed.
Rhizoma Angiopteridis Officinalis: little hardship, cold.GUIXIN, liver, gallbladder meridian.Tranquilizing by nourishing the heart, clearing heat for detumescence, cough-relieving.Be used for the neurasthenia, schizophrenia, icterohepatitis, mumps, carbuncle, venom, pneumonia, cough, diseases such as coronary heart disease.
Periostracum Serpentis: sweet, salty, flat.Return Liver Channel.Dispel the wind, arresting convulsion, nebula removing, antipruritic, removing toxic substances and promoting subsidence of swelling.Be used for infantile convulsion and twitch cornea cataracta, rubella pruritus, aphtha, furunculosis, diseases such as scald.
Radix Cynanchi Paniculati: hot, hot, return spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching, promoting blood circulation and detoxication, detumescence is used for gastropathy, toothache, rheumatic arthralgia, lumbago, epigastric pain, cholecystitis, the urine water conservancy is had loose bowels dysentery, eczema, urticaria, venom.
Olive: little hardship, flat.Loosening bowel to relieve constipation, skin ulcer is held back in detoxifcation.Be used for the dryness of the intestine constipation, burn due to hot liquid or fire, hypertension, hyperlipidemia, coronary heart disease etc.
Radix Codonopsis: sweet, flat.Return spleen, lung meridian.QI invigorating, promote the production of body fluid, nourish blood.Be used for the empty asthenia of body of deficiency of QI in middle-JIAO, lung qi loses empty cough tachypnea, and breathing hard that hinder in gas Tianjin two is thirsty, dizzy cardiopalmus etc.
Fructus Ligustri Lucidi: sweet, bitter, cool.Return liver, kidney channel.Liver and kidney tonifying, clearind deficient heat makes eye bright.Be used for Light-headedness, soreness of the waist and knees, cards such as tinnitus.
Chaetomers cleftlip grass: sweet, cool.Removing stasis to stop bleeding, the granulation promoting pain relieving.Be used for coronary heart disease, angina pectoris, Peptic Ulcers, hemorrhage disease such as grade.
Rhizoma Corydalis: hot, bitter, warm.Return liver, stomach, the heart, lung, spleen channel.Invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.Be used for all pains of trusted subordinate's waist knee joint, menoxenia, traumatic injury etc.
Fructus Piperis Longi: hot, hot.Return spleen, stomach, large intestine, lung, bladder, liver, kidney channel.Warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving.Be used for coldness and pain in the epigastrium, headache, toothache, nasal sinusitis, diseases such as angina pectoris are had loose bowels in vomiting.
Viral myocarditis belongs to motherland's medical science palpitation with fear, palpitation with a distress feeling, the thoracic obstruction, sick category such as dizzy.The patient is many lost by plain body empty, the deficiency of both vital energy and Yin of the heart, so that after their early stage experiences seasonal pathogen, evil poison invasion immediately, in accumulate in the heart the moon of more feeling frustrated.Heresy is stayed and is not gone, and heart arteries and veins is impaired, hematogenous blockage.Radix Cochleariae officinalis grass temperature qualcomm meridian, promoting blood circulation and stopping pain among the present invention, for monarch drug, Ilex purpurea Hassk.[I.chinensis Sims heat-clearing and toxic substances removing, invigorate blood circulation, the invigorating middle warmer of Radix Glycyrrhizae QI invigorating, the detoxifcation pain relieving, the Bulbus Lilii yin nourishing is calmed the nerves, the oenothera rosea L' Her. Ex Aif eliminating toxic substances to remove stasis, is ministerial drug, the Rhizoma Polygoni Cuspidati detoxification and removing stasis, scutellaria detoxification, Rhizoma Angiopteridis Officinalis tranquilizing by nourishing the heart, Periostracum Serpentis arresting convulsion detoxifcation, Radix Cynanchi Paniculati, olive promoting blood circulation and detoxication, Radix Codonopsis, Fructus Ligustri Lucidi supplementing QI for promoting the production of body fluid, chaetomers cleftlip grass, Rhizoma Corydalis blood-activating analgetic, the Piper longum warming middle-JIAO to relieve pain.All medicines share the effect of playing supplementing QI and nourishing YIN, detoxification and removing stasis, blood-promoting and mind-easing altogether, find through clinical practice, and viral myocarditis is had unique curative effect.
Chinese medicine composition of the present invention was in 2006 to 2010 clinical observation viral myocarditis 80 routine patients, and clinical report is as follows:
1, physical data
Among the 80 routine patients, male 47 examples, women 33 examples, 19~45 years old age, average 32 ± 6.8 years old, the course of disease 14 days~6 months.
2, diagnostic criteria
" traditional Chinese medical science disease diagnosis criterion of therapeutical effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Clinical manifestation is: uncomfortable in chest or breast dull pain, severe palpitation, dizziness, weakly breathe hard, spontaneous sweating, heating, the nausea of feeling sick, xerostomia drinking-water, joint aches.The heart sign has cardiac dilatation, arrhythmia heart murmur, hear sounds low blunt etc.
3, Therapeutic Method
3.1 prescription: Radix Cochleariae officinalis grass 40g, Ilex purpurea Hassk.[I.chinensis Sims 35g, Radix Glycyrrhizae 35g, Bulbus Lilii 30g, oenothera rosea L' Her. Ex Aif 25g, Rhizoma Polygoni Cuspidati 25g, Radix Scutellariae 22g, Rhizoma Angiopteridis Officinalis 22g, Periostracum Serpentis 16g, Radix Cynanchi Paniculati 16g, olive 16g, Radix Codonopsis 16g, Fructus Ligustri Lucidi 15g, chaetomers cleftlip grass 15g, Rhizoma Corydalis 12g, Piper longum 3g.
3.2 preparation and using method: said medicine technology is routinely made decoction, and 1 dose of every day, every day 2 times, 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 formulate with reference to " clinical disease diagnosis is according to curing the improvement standard ":
Cure: performance complete obiterations such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma, it is normal that electrocardiogram recovers, and it is normal that myocardium enzyme is recovered, the no abnormal performance of Color Sonography.
Produce effects: performances such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma significantly alleviate, and electrocardiogram recovers normally substantially, and it is normal that myocardium enzyme is recovered, the no abnormal performance of Color Sonography.
Effectively: performances such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma alleviate, the electrocardiogram mile abnormality, and it is normal that myocardium enzyme is recovered, the Color Sonography mile abnormality.
Invalid: performance such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma does not alleviate, and electrocardiographic abnormality does not improve, myocardium enzyme is not improved, and Color Sonography does not improve.
4.2 result: among the 80 routine patients, cure 45 examples (56.25%), produce effects 19 examples (23.75%), effective 12 examples (15%), invalid 4 examples (5%), total effective rate is 95%.
5, model case
5.1 Lee, the man, 32 years old, heating, uncomfortable in chest, cardio palmus shape, CTnI5.8ng/ml, CK-MB146U/L, Cox Ab IgM (+) headache appearred, in patient's cause half a year flu back.Electrocardio diagram: sinus rhythm, 89 times/min of heart rate; Accidental ventricular premature contraction; V4, V5, V6 lead, and the T ripple is low puts down; The Color Sonography no abnormality seen.Be diagnosed as viral myocarditis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and cardiopalmus, attack times uncomfortable in chest obviously reduce, continue to take 2 courses for the treatment of, ambulatory electrocardiogram prompting idol has ventricular premature contraction, and the S-T section is normal, the cardiac muscle zymetology normally continues to take 1 course for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year and do not had recurrence.
5.2 Chen, the woman 42 years old, consciously sharply beats in the heart, is panic-stricken, shortness of breath and fatigue, spiritlessness and too weak to speak, rapid pulse, CTnI6.2ng/ml, CK-MB132U/L, Cox Ab IgM (+).Electrocardio diagram: sinus rhythm, 78 times/min of heart rate; V4, V5, V6 lead, and the T ripple is low puts down; The Color Sonography no abnormality seen.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, and continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after 1 year and do not had recurrence.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only for explanation the present invention to the present invention without limits.
Embodiment 1, a kind of Chinese medicine composition for the treatment of viral myocarditis is to be made by Radix Cochleariae officinalis grass 30g, Ilex purpurea Hassk.[I.chinensis Sims 25g, Radix Glycyrrhizae 25g, Bulbus Lilii 25g, oenothera rosea L' Her. Ex Aif 20g, Rhizoma Polygoni Cuspidati 20g, Radix Scutellariae 20g, Rhizoma Angiopteridis Officinalis 20g, Periostracum Serpentis 10g, Radix Cynanchi Paniculati 10g, olive 10g, Radix Codonopsis 10g, Fructus Ligustri Lucidi 10g, chaetomers cleftlip grass 10g, Rhizoma Corydalis 10g, Piper longum 1g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of viral myocarditis is to be made by Radix Cochleariae officinalis grass 40g, Ilex purpurea Hassk.[I.chinensis Sims 35g, Radix Glycyrrhizae 35g, Bulbus Lilii 30g, oenothera rosea L' Her. Ex Aif 25g, Rhizoma Polygoni Cuspidati 25g, Radix Scutellariae 22g, Rhizoma Angiopteridis Officinalis 22g, Periostracum Serpentis 16g, Radix Cynanchi Paniculati 16g, olive 16g, Radix Codonopsis 16g, Fructus Ligustri Lucidi 15g, chaetomers cleftlip grass 15g, Rhizoma Corydalis 12g, Piper longum 3g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of viral myocarditis is to be made by Radix Cochleariae officinalis grass 50g, Ilex purpurea Hassk.[I.chinensis Sims 40g, Radix Glycyrrhizae 40g, Bulbus Lilii 40g, oenothera rosea L' Her. Ex Aif 30g, Rhizoma Polygoni Cuspidati 30g, Radix Scutellariae 30g, Rhizoma Angiopteridis Officinalis 30g, Periostracum Serpentis 20g, Radix Cynanchi Paniculati 20g, olive 20g, Radix Codonopsis 20g, Fructus Ligustri Lucidi 20g, chaetomers cleftlip grass 20g, Rhizoma Corydalis 15g, Piper longum 5g.

Claims (2)

1. Chinese medicine composition for the treatment of viral myocarditis is characterized in that it is to be made by following raw material medicaments:
Radix Cochleariae officinalis grass 30-50 part, Ilex purpurea Hassk.[I.chinensis Sims 25-40 part, Radix Glycyrrhizae 25-40 part, Bulbus Lilii 25-40 part, oenothera rosea L' Her. Ex Aif 20-30 part, Rhizoma Polygoni Cuspidati 20-30 part, Radix Scutellariae 20-30 part, Rhizoma Angiopteridis Officinalis 20-30 part, Periostracum Serpentis 10-20 part, Radix Cynanchi Paniculati 10-20 part, olive 10-20 part, Radix Codonopsis 10-20 part, Fructus Ligustri Lucidi 10-20 part, chaetomers cleftlip grass 10-20 part, Rhizoma Corydalis 10-15 part, Piper longum 1-5 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:
40 parts of Radix Cochleariae officinalis grass, 35 parts of Ilex purpurea Hassk.[I.chinensis Sims, 35 parts in Radix Glycyrrhizae, 30 parts of Bulbus Liliies, 25 parts of oenothera rosea L' Her. Ex Aif, 25 parts of Rhizoma Polygoni Cuspidati, 22 parts of Radix Scutellariaes, 22 parts of Rhizoma Angiopteridis Officinaliss, 16 parts of Periostracum Serpentiss, 16 parts of Radix Cynanchi Paniculatis, 16 parts of olives, 16 parts of Radix Codonopsis, 15 parts of Fructus Ligustri Lucidi, 15 parts of chaetomers cleftlip grass, 12 parts of Rhizoma Corydalis, 3 parts of Piper longums.
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Cited By (6)

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CN103948682A (en) * 2014-05-13 2014-07-30 陈雪 Traditional Chinese medicine for treating arrhythmia caused by insufficiency of heart blood
CN104306867A (en) * 2014-11-04 2015-01-28 郝晓臣 Traditional Chinese medicine preparation for curing viral myocarditis and preparation method
CN104352795A (en) * 2014-11-28 2015-02-18 张雪杰 Traditional Chinese medicine for treating yin-yang deficiency type viral myocarditis
CN105168406A (en) * 2015-10-28 2015-12-23 谢贤德 Traditional Chinese medicine composite for treating viral myocarditis and preparing method and application thereof
CN105582528A (en) * 2016-02-24 2016-05-18 薛艳 Sugar pill for treating pediatric viral myocarditis and preparation method thereof
CN105748888A (en) * 2016-04-13 2016-07-13 董伟 Traditional Chinese medicine composition for treating viral myocarditis

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103948682A (en) * 2014-05-13 2014-07-30 陈雪 Traditional Chinese medicine for treating arrhythmia caused by insufficiency of heart blood
CN104306867A (en) * 2014-11-04 2015-01-28 郝晓臣 Traditional Chinese medicine preparation for curing viral myocarditis and preparation method
CN104352795A (en) * 2014-11-28 2015-02-18 张雪杰 Traditional Chinese medicine for treating yin-yang deficiency type viral myocarditis
CN105168406A (en) * 2015-10-28 2015-12-23 谢贤德 Traditional Chinese medicine composite for treating viral myocarditis and preparing method and application thereof
CN105582528A (en) * 2016-02-24 2016-05-18 薛艳 Sugar pill for treating pediatric viral myocarditis and preparation method thereof
CN105748888A (en) * 2016-04-13 2016-07-13 董伟 Traditional Chinese medicine composition for treating viral myocarditis

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