CN101628116A - Pharmaceutical composition for treating herpes zoster - Google Patents

Pharmaceutical composition for treating herpes zoster Download PDF

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Publication number
CN101628116A
CN101628116A CN200910090819A CN200910090819A CN101628116A CN 101628116 A CN101628116 A CN 101628116A CN 200910090819 A CN200910090819 A CN 200910090819A CN 200910090819 A CN200910090819 A CN 200910090819A CN 101628116 A CN101628116 A CN 101628116A
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CN
China
Prior art keywords
pharmaceutical composition
vitamin
medicine
composition according
herpes zoster
Prior art date
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Pending
Application number
CN200910090819A
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Chinese (zh)
Inventor
宋泽龙
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Individual
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Individual
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Publication date
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Priority to CN200910090819A priority Critical patent/CN101628116A/en
Publication of CN101628116A publication Critical patent/CN101628116A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a pharmaceutical composition for treating herpes zoster, which comprises the following components by weight percent: 14%-32% of antiviral drug, 41%-64% of local anesthetic, 14%-32% of drug for treating neuritis and 0.3%-1% of cortical hormone drug and drug carrier. The pharmaceutical composition can shorten the disease course and rapidly relief the suffering to the maximum extent due to mutual collaboration and mutual enhancement of all components in the pharmaceutical composition, and the medication is convenient and easy, thereby being easy to accept by patients.

Description

The pharmaceutical composition of treatment herpes zoster
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of herpes zoster.
Background technology
Herpes zoster is a kind of infectious neuritis dermatoses that herpesvirus causes.The shallow table nerve and the skin that mainly involve intercostal nerves, nervi trigeminus and other positions.Pain and herpes are one of feature of primary disease, and especially for the gerontal patient, pain is violent unusually.If malpractice, some patient still has the pain sequela after erythra disappears fully.
Summary of the invention
Technical problem to be solved by this invention is: a kind of pharmaceutical composition for the treatment of herpes zoster is provided, based on this pharmaceutical composition, can alleviates the patient suffering rapidly and effectively, shorten the course of disease.
In order to address the above problem, the invention discloses a kind of pharmaceutical composition for the treatment of herpes zoster, by weight percentage, said composition comprises:
Antiviral drugs 14%~32%
Local anesthetic 41%~64%
Treat neuritic medicine 14%~32%
Corticosteroids medicine 0.3%~1%
And pharmaceutical carrier.
Preferably, described antiviral drugs is: ribavirin, acyclovir, penciclovir, Flos Lonicerae, Radix Isatidis, Folium Isatidis, Pheretima or Realgar.
Preferably, described local anesthetic is: lignocaine, procaine or tetracaine.
Preferably, the neuritic medicine of described treatment is: vitamin B 1, vitamin B 2, vitamin B 6, vitamin B 12Or vitamin C.
Preferably, described corticosteroids medicine is: dexamethasone, prednisone, hydrocortisone, Pevisone, fluocinolone acetonide, triamcinolone acetonide.
Preferably, described pharmaceutical carrier is: distilled water, sodium chloride solution, newborn matter base or oil base.
In the present invention: on antiviral basis, local anesthetic strengthened by corticoid class medicine and treatment neuritis class medicine is repaired neural effect, strengthened the tolerance of body simultaneously to disease, because collaborative mutually, the mutual enhanced effect of each component of medicine, at utmost shorten the course of disease, remove misery rapidly, medication is convenient and easy, and the patient is acceptant.
The specific embodiment
For above-mentioned purpose of the present invention, feature and advantage can be become apparent more, the present invention is further detailed explanation below in conjunction with the specific embodiment.
The pharmaceutical composition that the present invention treats herpes zoster mainly comprises following four kinds of compositions:
One, antiviral ingredients, can adopt the combination of following one or several medicines: ribavirin, acyclovir or penciclovir, some Chinese medicine ingredients with antiviral efficacy are also passable, for example, and Flos Lonicerae, Radix Isatidis, Folium Isatidis, Pheretima, Realgar etc.;
Two, the local anesthesia composition plays sealing process to nerve root, can adopt following one or several medicines: lignocaine, procaine or tetracaine;
Three, treat neuritic composition, be used for trophic nerve nuclear and repair nerve, can adopt following one or several medicines: vitamin B 1, vitamin B 6, vitamin B 12, vitamin C;
Four, 17-hydroxy-11-dehydrocorticosterone composition, be used to reduce herpes zoster and ooze out, eliminate herpes, mitigation symptoms, can adopt following one or several medicines: dexamethasone, prednisone, hydrocortisone, Pevisone, fluocinolone acetonide, triamcinolone acetonide, or other glucocorticoid.
Pharmaceutical composition of the present invention can be for liquid, also can be ointment, and this depends on the kind of the pharmaceutical carrier of above-mentioned four kinds of compositions.For example, pharmaceutical carrier can be distilled water, 0.9% sodium chloride injection, newborn matter base or oil base, for example vaseline oil base.
If desire configuration aforementioned pharmaceutical compositions can adopt following method:
With weight portion be
14~32 parts of antiviral drugs
41~64 parts of local anesthetics
Treat 14~32 parts of neuritic medicines
0.3~1 part of corticosteroids medicine
Be added in the pharmaceutical carrier, form the said mixture of 100 weight portions.The composition that wherein each kind of component can adopt and the type of pharmaceutical carrier have been described in detail in the above, do not repeat them here.
Embodiment one:
At normal temperatures, with 100~200 milligrams of ribavirins, vitamin B 1300~400 milligrams of 100~200 milligrams, 2~5 milligrams of dexamethasone, lignocaine are dissolved in 25 milliliter 0.9% the sodium chloride injection.
Therapeutic Method:
With the medicine of above-mentioned configuration, immerse sterile gauze, after the conventional cleaning of patient's illing skin, directly soak allows the affected part wet through in the affected part as far as possible, twice on the one.
Embodiment two:
At normal temperatures, with 1 milliliter of ribavirin injection (containing 100 milligrams of ribavirins), lignocaine injection 20 milliliters of (containing 400 milligrams of lignocaine), vitamin Bs 1Injection (contains vitamin B for 2 milliliters 1100 milligrams), 2 milliliters of (containing 2 milligrams of dexamethasone) compatibilities of dexamethasone injection.
Therapeutic Method:
With the medicine of above-mentioned configuration, immerse sterile gauze, after the conventional cleaning of patient's illing skin, directly soak allows the affected part wet through in the affected part as far as possible, twice on the one.Also the medicine of above-mentioned configuration can be directly used in partial closure.
Embodiment three:
At normal temperatures, with 100 milligrams of ribavirins, 400 milligrams of lignocaine, vitamin B 12 milligrams of 100 milligrams, dexamethasone are added in the vaseline emulsifiable pastes of 25 grams.
Therapeutic Method:
With patient's illing skin is conventional clean after, the ointment of above-mentioned configuration directly is applied in the affected part, twice on the one.
Observe 100 routine patients, clinical treatment is the result show: soak 30 minutes to 1 hour, and pain relieving fully, in 24 hours, the obvious atrophy of vesicle, in addition shrivelled, incrustation decortication in 3~5 days.The present invention treats banded antiherpetic compositions by means of antiviral drugs, neuritic medicine of treatment and the synergy that reduces the corticosteroids medicine and the local anesthesia analgesic drug product that ooze out mitigation symptoms, at utmost shortened the course of disease, remove the patient suffering rapidly, have better curative effect; And medication is convenient, economical; The patient is acceptant.
More than a kind of pharmaceutical composition for the treatment of herpes zoster provided by the present invention is described in detail, used specific case herein principle of the present invention and embodiment are set forth, the explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof; Simultaneously, for one of ordinary skill in the art, according to thought of the present invention, the part that all can change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.

Claims (6)

1, a kind of pharmaceutical composition for the treatment of herpes zoster is characterized in that said composition comprises by weight percentage:
Antiviral drugs 14%~32%
Local anesthetic 41%~64%
Treat neuritic medicine 14%~32%
Corticosteroids medicine 0.3%~1%
And pharmaceutical carrier.
2, pharmaceutical composition according to claim 1 is characterized in that, described antiviral drugs is: ribavirin, acyclovir, penciclovir, Flos Lonicerae, Radix Isatidis, Folium Isatidis, Pheretima or Realgar.
3, pharmaceutical composition according to claim 1 is characterized in that, described local anesthetic is: lignocaine, procaine or tetracaine.
4, pharmaceutical composition according to claim 1 is characterized in that, the neuritic medicine of described treatment is: vitamin B 1, vitamin B 6, vitamin B 12Or vitamin C.
5, pharmaceutical composition according to claim 1 is characterized in that, described corticosteroids medicine is: dexamethasone, prednisone, hydrocortisone, Pevisone, fluocinolone acetonide, triamcinolone acetonide.
6, pharmaceutical composition according to claim 1 is characterized in that, described pharmaceutical carrier is: distilled water, sodium chloride solution, newborn matter base or oil base.
CN200910090819A 2009-08-10 2009-08-10 Pharmaceutical composition for treating herpes zoster Pending CN101628116A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN200910090819A CN101628116A (en) 2009-08-10 2009-08-10 Pharmaceutical composition for treating herpes zoster

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200910090819A CN101628116A (en) 2009-08-10 2009-08-10 Pharmaceutical composition for treating herpes zoster

Publications (1)

Publication Number Publication Date
CN101628116A true CN101628116A (en) 2010-01-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN200910090819A Pending CN101628116A (en) 2009-08-10 2009-08-10 Pharmaceutical composition for treating herpes zoster

Country Status (1)

Country Link
CN (1) CN101628116A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040856A (en) * 2012-12-26 2013-04-17 李忠 Medicine composition for treating varicella zoster virus disease
CN104415050A (en) * 2013-08-31 2015-03-18 何伊仁 External spray for treating viral herpes
US20160015731A1 (en) * 2013-03-13 2016-01-21 Nal Pharmaceuticals, Ltd. A topical antiviral composition containing a local anesthetic and method of making the same
CN107714682A (en) * 2017-12-13 2018-02-23 阜阳市平衡医疗保健器械有限公司 A kind of medicine for treating lumbocrural pain

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103040856A (en) * 2012-12-26 2013-04-17 李忠 Medicine composition for treating varicella zoster virus disease
US20160015731A1 (en) * 2013-03-13 2016-01-21 Nal Pharmaceuticals, Ltd. A topical antiviral composition containing a local anesthetic and method of making the same
US10682370B2 (en) * 2013-03-13 2020-06-16 Nal Pharmaceutical Group Limited Topical antiviral composition containing a local anesthetic and method of making the same
CN104415050A (en) * 2013-08-31 2015-03-18 何伊仁 External spray for treating viral herpes
CN107714682A (en) * 2017-12-13 2018-02-23 阜阳市平衡医疗保健器械有限公司 A kind of medicine for treating lumbocrural pain

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Open date: 20100120