CN106880670B - A kind of medicine for treating scabies - Google Patents

A kind of medicine for treating scabies Download PDF

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CN106880670B
CN106880670B CN201710190166.8A CN201710190166A CN106880670B CN 106880670 B CN106880670 B CN 106880670B CN 201710190166 A CN201710190166 A CN 201710190166A CN 106880670 B CN106880670 B CN 106880670B
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grams
medicine
parts
scabies
medicinal powder
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CN106880670A (en
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顾银根
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a kind of medicine for treating scabies, the components by weight percent of the medicine are as follows：13 parts of rhubarb, 12 parts of camphor, 34 parts of sulphur, 12 parts of corter pseudolaricis, 1 part of calamine, 1 part of zinc oxide；Each components by weight percent is well mixed, is ground into 80~100 mesh medicinal powder, adds 25 grams of glycerine in every 50 grams of medicinal powder, 25 grams of vaseline stir, external-applied ointment is made in sterilization.The medicine of the present invention, advantages of simple is formulated, each component cooperates, complemented each other, and there are obvious curative effects to treatment scabies, controls difficulty in relapse after healing, can effectively kill sarcoptic mite, anti-itch detoxification, hygroscopic sore, have no toxic side effect.Cost is cheap, can be widely applied to each department, particularly rural area shortage of medical services and medicines area, simultaneously, mitigates common people's burden in effectively treatment scabies.

Description

A kind of medicine for treating scabies
Technical field
The present invention relates to field of traditional Chinese, is specifically related to a kind of external used medicine for treating scabies.
Background technology
Scabies, the traditional Chinese medical science be referred to as " stubborn dermatitis ", be by itch mite in human body skin epidermis caused contagious infection skin Skin disease, can between contactee spread and epidemic.Clinical manifestation has papule, blister and tunnel, pruritus scroti with the tender part of skin Property tubercle, night itch aggravation with the characteristics of.Skin lesion is pinhead-sized papulo-vesicle and bleb.It can often be found by sarcoptic mite at webs The tunnel excavated, female adult can be chosen with needle point in tunnel face.This is the peculiar symptom of scabies, is often accompanied by night itching.
Medicine traditional at present, which exists, treats the deficiencies of not thorough, simply Symptomatic position is played temporary slow Solution, handle does not hide thoroughly kills in subcutaneous worm's ovum.The procreation mode of sarcoptic mite female adult is that 0.5-5mm tunnel is chiseled in skin Road, then ovulated in tunnel, ovum is hatched 3-4 days in tunnel and forms larva, and in general medicine is difficult to go deep into where worm's ovum Worm's ovum is killed in tunnel, therefore is only the adult for killing skin surface, is often recurred again after 3-4 days.Medication is repeatedly easy repeatedly Develop immunity to drugs, protracted inflammation is not cured.
The content of the invention
It is an object of the invention to provide one kind can effectively kill scabies worm, and controls difficulty in relapse after healing, mitigates patient's pain Bitter scabies medicine thing.
In order to solve the above technical problems, the present invention adopts the following technical scheme that：
A kind of medicine for treating scabies, it is characterised in that：The components by weight percent of the medicine is as follows：Rhubarb 1-3 parts, camphor 1-2 parts, sulphur 3-4 parts, corter pseudolaricis 1-2 parts, 1 part of calamine, 1 part of zinc oxide；Each components by weight percent is well mixed, crushed Into 80~100 mesh medicinal powder, 25 grams of glycerine of addition, 25 grams of vaseline stir in every 50 grams of medicinal powder, and sterilization is made outer Use ointment.
The medicine of the invention described above treatment scabies is further characterized in that：75mg is added in per the above-mentioned external-applied ointments of 100g ~750mg dexamethasone powder, mixing are mixed thoroughly.
Because the secretion of sarcoptic mite stimulates skin, there is erythema, papule, blister, tubercle etc. plus factor, skins such as scratchings The scabies patient of secondary eczematization skin lesion, dexamethasone is added in the medicine of the present invention, external application can mitigate and prevent group The reaction to inflammation is knitted, so as to the performance to reduce inflammation.Suppress inflammatory cell, including macrophage and leucocyte are in inflammation part Gather, and suppress phagocytosis, the release of lysosomal enzyme and the synthesis and release of inflammation chemistry intermediary.
The medicine for the treatment of scabies provided by the invention, has sterilization, antipruritic and antisepsis, is formulated advantages of simple, each group Divide and cooperate, complement each other, there are obvious curative effects to treatment scabies, control difficulty in relapse after healing, can effectively kill sarcoptic mite, antipruritic solution Poison, hygroscopic sore, has no toxic side effect.Manufacture craft is simple, and cost is cheap, the characteristics of meeting the traditional Chinese medical science " letter, just, test, be honest and clean ", can be with Each department, particularly rural area shortage of medical services and medicines area are widely used in, simultaneously, mitigate common people's burden in effectively treatment scabies.
Embodiment
To enable your auditor and the public to further appreciate that the feature and its advantage of the present invention, spy is with embodiment to this The embodiment of invention is described in detail as follows：
The order of severity or age are infected according to scabies patient, can accordingly adjust the content of each composition in medicine of the present invention.
Embodiment one：
10 grams of rhubarb, 5 grams of camphor, 20 grams of sulphur, 5 grams of corter pseudolaricis, 5 grams of calamine, 5 grams of zinc oxide are taken, by this six kinds Bulk drug is well mixed by each components by weight percent, is ground into 50 grams of 80~100 mesh medicinal powder, and 25 grams of addition is sweet in 50 grams of medicinal powder Oil, 25 grams of vaseline stir, and 100 grams of external-applied ointments are made in sterilization.
In use, medicine is coated onto affected part, once in the morning and once at night, it is used continuously five days and cures, if any scrotum knot Section then needs continuous use ten days.
Embodiment two：
20 grams of rhubarb, 20 grams of camphor, 30 grams of sulphur, 10 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization.Application method is same as above.
Embodiment three：
10 grams of rhubarb, 10 grams of camphor, 40 grams of sulphur, 20 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization.Application method is same as above.
Example IV：
30 grams of rhubarb, 10 grams of camphor, 30 grams of sulphur, 10 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization.Application method is same as above.
The scabies patient changed for the concurrent eczema sample of skin, according to eczema situation, scabies can be treated in the invention described above Medicine in add dexamethasone powder, the amount of addition is：75mg~750mg dexamethasone is added in per the above-mentioned external-applied ointments of 100g Powder, it is sufficiently mixed after mixing thoroughly, medicine is coated onto affected part, once in the morning and once at night, is used continuously five days and cures, if any scrotum Tubercle then needs continuous use ten days.
Embodiment five：
10 grams of rhubarb, 5 grams of camphor, 20 grams of sulphur, 5 grams of corter pseudolaricis, 5 grams of calamine, 5 grams of zinc oxide are taken, by this six kinds Bulk drug is well mixed by each components by weight percent, is ground into 50 grams of 80~100 mesh medicinal powder, and 25 grams of addition is sweet in 50 grams of medicinal powder Oil, 25 grams of vaseline stir, and 100 grams of external-applied ointments are made in sterilization, 75mg is added in 100 grams of external-applied ointments Rice loose powder is filled in, is sufficiently mixed and mixes thoroughly.In use, medicine is coated onto affected part, once in the morning and once at night, continuous use is controlled for five days More, continuous use ten days is then needed if any scrotum tubercle.
Embodiment six：
20 grams of rhubarb, 20 grams of camphor, 30 grams of sulphur, 10 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization, are added in 200 grams of external-applied ointments 1500mg dexamethasone powder, is sufficiently mixed and mixes thoroughly.Application method is same as above.
Embodiment seven：
10 grams of rhubarb, 10 grams of camphor, 40 grams of sulphur, 20 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization, are added in 200 grams of external-applied ointments 750mg dexamethasone powder, is sufficiently mixed and mixes thoroughly.Application method is same as above.
Embodiment eight：
15 grams of rhubarb, 15 grams of camphor, 40 grams of sulphur, 10 grams of corter pseudolaricis, 10 grams of calamine, 10 grams of zinc oxide are taken, by this Six kinds of bulk drugs are well mixed by each components by weight percent, are ground into 100 grams of 80~100 mesh medicinal powder, and 50 are added in 100 grams of medicinal powder Gram glycerine, 50 grams of vaseline stir, and 200 grams of external-applied ointments are made in sterilization, are added in 200 grams of external-applied ointments 750mg dexamethasone powder, is sufficiently mixed and mixes thoroughly.Application method is same as above.

Claims (3)

  1. A kind of 1. medicine for treating scabies, it is characterised in that：The components by weight percent of the medicine is as follows：Rhubarb 1-3 parts, camphor 1- 2 parts, sulphur 3-4 parts, corter pseudolaricis 1-2 parts, 1 part of calamine, 1 part of zinc oxide；Each components by weight percent is well mixed, is ground into 80~100 mesh medicinal powder, add 25 grams of glycerine in every 50 grams of medicinal powder, 25 grams of vaseline stir, and external application is made in sterilization Ointment, 75mg~750mg dexamethasone powder often is added in the 100g external-applied ointments, mixing is mixed thoroughly.
  2. 2. the medicine for the treatment of scabies according to claim 1, it is characterised in that：The components by weight percent of the medicine is as follows：It is raw 2 parts of rheum officinale, 1 part of camphor, 4 parts of sulphur, 1 part of corter pseudolaricis, 1 part of calamine, 1 part of zinc oxide；Each components by weight percent is mixed equal It is even, 80~100 mesh medicinal powder are ground into, add 25 grams of glycerine in every 50 grams of medicinal powder, 25 grams of vaseline stir, sterilization External-applied ointment is made, adds 75mg~750mg dexamethasone powder in every 100g external-applied ointments, mixing is mixed thoroughly.
  3. 3. the medicine for the treatment of scabies according to claim 1 or 2, it is characterised in that：Add in per the above-mentioned external-applied ointments of 100g Enter 375mg dexamethasone powder, mixing is mixed thoroughly.
CN201710190166.8A 2017-03-28 2017-03-28 A kind of medicine for treating scabies Active CN106880670B (en)

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CN201710190166.8A CN106880670B (en) 2017-03-28 2017-03-28 A kind of medicine for treating scabies

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CN106880670B true CN106880670B (en) 2018-02-23

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* Cited by examiner, † Cited by third party
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CN113171377A (en) * 2021-05-21 2021-07-27 龙小山 External liquid medicine for treating skin diseases and preparation method and application thereof

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CN100358547C (en) * 2003-07-10 2008-01-02 姜延德 Tinea cruris ointment

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