CN101616683A - 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 - Google Patents

用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 Download PDF

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Publication number
CN101616683A
CN101616683A CN200880001665A CN200880001665A CN101616683A CN 101616683 A CN101616683 A CN 101616683A CN 200880001665 A CN200880001665 A CN 200880001665A CN 200880001665 A CN200880001665 A CN 200880001665A CN 101616683 A CN101616683 A CN 101616683A
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China
Prior art keywords
cyclosporine
meala
derivative
etval
csa
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Pending
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CN200880001665A
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English (en)
Chinese (zh)
Inventor
保罗·伯纳迪
格里哥尔·弗格尼奥克斯
拉斐尔·克莱博
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Debiopharm SA
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Debiopharm SA
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Publication date
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Priority to CN201510378165.7A priority Critical patent/CN105056207A/zh
Publication of CN101616683A publication Critical patent/CN101616683A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN200880001665A 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 Pending CN101616683A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510378165.7A CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87841407P 2007-01-04 2007-01-04
US60/878,414 2007-01-04

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510378165.7A Division CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Publications (1)

Publication Number Publication Date
CN101616683A true CN101616683A (zh) 2009-12-30

Family

ID=39514754

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201510378165.7A Pending CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素
CN200880001665A Pending CN101616683A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201510378165.7A Pending CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Country Status (12)

Country Link
US (1) US8450281B2 (enExample)
EP (1) EP2124992A2 (enExample)
JP (1) JP5801534B2 (enExample)
CN (2) CN105056207A (enExample)
AU (1) AU2008204344B2 (enExample)
BR (1) BRPI0806265A2 (enExample)
CA (1) CA2674296C (enExample)
HK (1) HK1210951A1 (enExample)
IL (1) IL199674A (enExample)
MX (1) MX2009007045A (enExample)
RU (1) RU2462262C2 (enExample)
WO (1) WO2008084368A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
AU2011214135B2 (en) 2010-02-09 2014-07-31 Neurovive Pharmaceutical Ab Sanglifehrin based compounds
WO2011098808A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
WO2011098805A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
CN103619336B (zh) 2010-12-20 2017-10-27 纽洛维弗制药有限公司 Sanglifehrin衍生物及其制备方法
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
AU2013259841A1 (en) 2012-05-07 2014-10-30 Novartis Ag Pharmacokinetic modulation with alisporivir
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
WO1999055321A1 (en) * 1998-04-24 1999-11-04 Mitokor Compounds and methods for treating mitochondria-associated diseases
ES2255275T3 (es) * 1998-07-01 2006-06-16 Debiopharm S.A. Nueva ciclosporina con perfil de actividad mejorado.
US6323039B1 (en) * 1999-06-22 2001-11-27 Mitokor Compositions and methods for assaying subcellular conditions and processes using energy transfer
US7368423B1 (en) 2001-12-05 2008-05-06 The Scripps Research Institute Composition and method for treating chronic allograft rejection
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy

Also Published As

Publication number Publication date
IL199674A (en) 2016-10-31
HK1210951A1 (en) 2016-05-13
RU2462262C2 (ru) 2012-09-27
AU2008204344B2 (en) 2013-01-31
US8450281B2 (en) 2013-05-28
MX2009007045A (es) 2009-10-07
CA2674296A1 (en) 2008-07-17
BRPI0806265A2 (pt) 2011-09-06
CA2674296C (en) 2015-11-24
JP5801534B2 (ja) 2015-10-28
WO2008084368A2 (en) 2008-07-17
US20100041593A1 (en) 2010-02-18
AU2008204344A1 (en) 2008-07-17
WO2008084368A8 (en) 2009-09-17
IL199674A0 (en) 2010-04-15
EP2124992A2 (en) 2009-12-02
RU2009129212A (ru) 2011-02-10
JP2010514834A (ja) 2010-05-06
CN105056207A (zh) 2015-11-18
WO2008084368A9 (en) 2009-02-26
AU2008204344A9 (en) 2012-06-28

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