RU2462262C2 - Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха - Google Patents
Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха Download PDFInfo
- Publication number
- RU2462262C2 RU2462262C2 RU2009129212/15A RU2009129212A RU2462262C2 RU 2462262 C2 RU2462262 C2 RU 2462262C2 RU 2009129212/15 A RU2009129212/15 A RU 2009129212/15A RU 2009129212 A RU2009129212 A RU 2009129212A RU 2462262 C2 RU2462262 C2 RU 2462262C2
- Authority
- RU
- Russia
- Prior art keywords
- meala
- etval
- methyl
- meleu
- csa
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87841407P | 2007-01-04 | 2007-01-04 | |
| USUS60/878,414 | 2007-01-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2009129212A RU2009129212A (ru) | 2011-02-10 |
| RU2462262C2 true RU2462262C2 (ru) | 2012-09-27 |
Family
ID=39514754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009129212/15A RU2462262C2 (ru) | 2007-01-04 | 2008-01-03 | Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8450281B2 (enExample) |
| EP (1) | EP2124992A2 (enExample) |
| JP (1) | JP5801534B2 (enExample) |
| CN (2) | CN101616683A (enExample) |
| AU (1) | AU2008204344B2 (enExample) |
| BR (1) | BRPI0806265A2 (enExample) |
| CA (1) | CA2674296C (enExample) |
| HK (1) | HK1210951A1 (enExample) |
| IL (1) | IL199674A (enExample) |
| MX (1) | MX2009007045A (enExample) |
| RU (1) | RU2462262C2 (enExample) |
| WO (1) | WO2008084368A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009098533A1 (en) * | 2008-02-08 | 2009-08-13 | Debiopharm Sa | Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy |
| ES2541853T3 (es) | 2010-02-09 | 2015-07-27 | Neurovive Pharmaceutical Ab | Compuestos basados en sangliferina |
| WO2011098808A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| WO2011098805A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| GB201008123D0 (en) | 2010-05-17 | 2010-06-30 | Biotica Tech Ltd | Novel compounds |
| ES2703433T3 (es) | 2010-12-20 | 2019-03-08 | Neurovive Pharmaceutical Ab | Derivados de sangliferina y métodos para su producción |
| JO3063B1 (ar) | 2011-03-29 | 2017-03-15 | Neurovive Pharmaceutical Ab | مركب مبتكر وطرق لانتاجه |
| BR112014027127A2 (pt) | 2012-05-07 | 2017-06-27 | Novartis Ag | modulação farmacocinética com alisporivir |
| AR090964A1 (es) | 2012-05-09 | 2014-12-17 | Novartis Ag | Proceso para la elaboracion de undecapeptidos ciclicos |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525590A (en) * | 1987-06-17 | 1996-06-11 | Sandoz Ltd. | Cyclosporins and their use as pharmaceuticals |
| US6927208B1 (en) * | 1998-07-01 | 2005-08-09 | Debiopharm S.A. | Cyclosporin with improved activity profile |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0148748B1 (ko) | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| CA2329709A1 (en) * | 1998-04-24 | 1999-11-04 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
| US6323039B1 (en) * | 1999-06-22 | 2001-11-27 | Mitokor | Compositions and methods for assaying subcellular conditions and processes using energy transfer |
| US7368423B1 (en) | 2001-12-05 | 2008-05-06 | The Scripps Research Institute | Composition and method for treating chronic allograft rejection |
| GB0320638D0 (en) * | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| WO2009098533A1 (en) * | 2008-02-08 | 2009-08-13 | Debiopharm Sa | Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy |
-
2008
- 2008-01-03 EP EP08702176A patent/EP2124992A2/en not_active Withdrawn
- 2008-01-03 AU AU2008204344A patent/AU2008204344B2/en not_active Ceased
- 2008-01-03 US US12/522,118 patent/US8450281B2/en not_active Expired - Fee Related
- 2008-01-03 CN CN200880001665A patent/CN101616683A/zh active Pending
- 2008-01-03 WO PCT/IB2008/000003 patent/WO2008084368A2/en not_active Ceased
- 2008-01-03 RU RU2009129212/15A patent/RU2462262C2/ru not_active IP Right Cessation
- 2008-01-03 BR BRPI0806265-0A patent/BRPI0806265A2/pt not_active Application Discontinuation
- 2008-01-03 CA CA2674296A patent/CA2674296C/en not_active Expired - Fee Related
- 2008-01-03 JP JP2009544475A patent/JP5801534B2/ja not_active Expired - Fee Related
- 2008-01-03 CN CN201510378165.7A patent/CN105056207A/zh active Pending
- 2008-01-03 MX MX2009007045A patent/MX2009007045A/es active IP Right Grant
-
2009
- 2009-07-02 IL IL199674A patent/IL199674A/en active IP Right Grant
-
2010
- 2010-05-20 HK HK15111764.4A patent/HK1210951A1/xx unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525590A (en) * | 1987-06-17 | 1996-06-11 | Sandoz Ltd. | Cyclosporins and their use as pharmaceuticals |
| US6927208B1 (en) * | 1998-07-01 | 2005-08-09 | Debiopharm S.A. | Cyclosporin with improved activity profile |
Non-Patent Citations (1)
| Title |
|---|
| Irwin WA., et al., "Mitochondrial dysfunction and apoptosis in myopathic mice with collagen VI deficiency." Nat Genet. 2003 Dec; 35(4): 367-71. Epub 2003 Nov 16. * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008204344A9 (en) | 2012-06-28 |
| WO2008084368A2 (en) | 2008-07-17 |
| AU2008204344B2 (en) | 2013-01-31 |
| WO2008084368A9 (en) | 2009-02-26 |
| WO2008084368A8 (en) | 2009-09-17 |
| IL199674A0 (en) | 2010-04-15 |
| US20100041593A1 (en) | 2010-02-18 |
| RU2009129212A (ru) | 2011-02-10 |
| CN105056207A (zh) | 2015-11-18 |
| CA2674296C (en) | 2015-11-24 |
| AU2008204344A1 (en) | 2008-07-17 |
| CN101616683A (zh) | 2009-12-30 |
| EP2124992A2 (en) | 2009-12-02 |
| JP5801534B2 (ja) | 2015-10-28 |
| CA2674296A1 (en) | 2008-07-17 |
| HK1210951A1 (en) | 2016-05-13 |
| US8450281B2 (en) | 2013-05-28 |
| MX2009007045A (es) | 2009-10-07 |
| JP2010514834A (ja) | 2010-05-06 |
| BRPI0806265A2 (pt) | 2011-09-06 |
| IL199674A (en) | 2016-10-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2462262C2 (ru) | Неиммуносупрессорный циклоспорин для лечения врожденной миопатии ульриха | |
| JP3089350B2 (ja) | シクロフィリンロタマーゼ活性の阻害剤 | |
| US8697657B2 (en) | Combination therapies using cyclosporine and aromatic cationic peptides | |
| US11154587B2 (en) | Use of peptides to stimulate the immune system | |
| BRPI0721259A2 (pt) | composto, composiÇço farmacÊutica, uso de composto, e, processo para a fabricaÇço de composto | |
| CN101939021B (zh) | 用于治疗肌营养不良症的非免疫抑制性环孢素 | |
| KR20070036033A (ko) | 보체 C5a 수용체 조절제를 이용한 신경계 증상의치료방법 | |
| HK1137364A (en) | Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy | |
| Zhang | Development of cyclophilin inhibitors for the treatment of pancreatitis | |
| HK1148665B (en) | Non-immunosuppressive cyclosporin for the treatment of muscular dystrophy | |
| LT5132B (lt) | Nepeptidiniai ccr1 receptorių antagonistai derinyje su ciklosporinu a širdies transplanto atmetimui gydyti |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20190104 |