BRPI0806265A2 - ciclosporina não-imunossupressora para tratamento de distrofia muscular congênita de ullrich - Google Patents
ciclosporina não-imunossupressora para tratamento de distrofia muscular congênita de ullrich Download PDFInfo
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- BRPI0806265A2 BRPI0806265A2 BRPI0806265-0A BRPI0806265A BRPI0806265A2 BR PI0806265 A2 BRPI0806265 A2 BR PI0806265A2 BR PI0806265 A BRPI0806265 A BR PI0806265A BR PI0806265 A2 BRPI0806265 A2 BR PI0806265A2
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- Prior art keywords
- derivative
- cyclosporin
- formula
- immunosuppressive
- csa
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
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- Chemical & Material Sciences (AREA)
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- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US87841407P | 2007-01-04 | 2007-01-04 | |
| US60/878,414 | 2007-01-04 | ||
| PCT/IB2008/000003 WO2008084368A2 (en) | 2007-01-04 | 2008-01-03 | Non-immunosuppressive cyclosporin for treatment of ullrich congenital muscular dystrophy |
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|---|---|
| BRPI0806265A2 true BRPI0806265A2 (pt) | 2011-09-06 |
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| EP (1) | EP2124992A2 (enExample) |
| JP (1) | JP5801534B2 (enExample) |
| CN (2) | CN101616683A (enExample) |
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| CA (1) | CA2674296C (enExample) |
| HK (1) | HK1210951A1 (enExample) |
| IL (1) | IL199674A (enExample) |
| MX (1) | MX2009007045A (enExample) |
| RU (1) | RU2462262C2 (enExample) |
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| WO2009098533A1 (en) * | 2008-02-08 | 2009-08-13 | Debiopharm Sa | Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy |
| JP5894935B2 (ja) | 2010-02-09 | 2016-03-30 | ニューロヴィベ プハルマセウトイカル エービー | サングリフェリン系化合物 |
| WO2011098805A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| WO2011098808A1 (en) | 2010-02-09 | 2011-08-18 | Biotica Technology Limited | Sanglifehrin based compounds |
| GB201008123D0 (en) | 2010-05-17 | 2010-06-30 | Biotica Tech Ltd | Novel compounds |
| CN103619336B (zh) | 2010-12-20 | 2017-10-27 | 纽洛维弗制药有限公司 | Sanglifehrin衍生物及其制备方法 |
| JO3063B1 (ar) | 2011-03-29 | 2017-03-15 | Neurovive Pharmaceutical Ab | مركب مبتكر وطرق لانتاجه |
| US20150133369A1 (en) | 2012-05-07 | 2015-05-14 | Steven Kovacs | Pharmacokinetic modulation with alisporivir |
| AR090964A1 (es) | 2012-05-09 | 2014-12-17 | Novartis Ag | Proceso para la elaboracion de undecapeptidos ciclicos |
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| EP0296122B1 (en) * | 1987-06-17 | 1993-09-29 | Sandoz Ag | Cyclosporins and their use as pharmaceuticals |
| GB2222770B (en) | 1988-09-16 | 1992-07-29 | Sandoz Ltd | Pharmaceutical compositions containing cyclosporins |
| US6268398B1 (en) * | 1998-04-24 | 2001-07-31 | Mitokor | Compounds and methods for treating mitochondria-associated diseases |
| BR9911724A (pt) * | 1998-07-01 | 2001-03-20 | Debiopharm Sa | Ciclosporina que tem um perfil de atividade melhorado |
| US6323039B1 (en) * | 1999-06-22 | 2001-11-27 | Mitokor | Compositions and methods for assaying subcellular conditions and processes using energy transfer |
| US7368423B1 (en) | 2001-12-05 | 2008-05-06 | The Scripps Research Institute | Composition and method for treating chronic allograft rejection |
| GB0320638D0 (en) * | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
| WO2009098533A1 (en) * | 2008-02-08 | 2009-08-13 | Debiopharm Sa | Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy |
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- 2008-01-03 RU RU2009129212/15A patent/RU2462262C2/ru not_active IP Right Cessation
- 2008-01-03 CN CN200880001665A patent/CN101616683A/zh active Pending
- 2008-01-03 US US12/522,118 patent/US8450281B2/en not_active Expired - Fee Related
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- 2008-01-03 AU AU2008204344A patent/AU2008204344B2/en not_active Ceased
- 2008-01-03 EP EP08702176A patent/EP2124992A2/en not_active Withdrawn
- 2008-01-03 CN CN201510378165.7A patent/CN105056207A/zh active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2008084368A8 (en) | 2009-09-17 |
| AU2008204344A9 (en) | 2012-06-28 |
| RU2462262C2 (ru) | 2012-09-27 |
| US20100041593A1 (en) | 2010-02-18 |
| CN101616683A (zh) | 2009-12-30 |
| JP5801534B2 (ja) | 2015-10-28 |
| HK1210951A1 (en) | 2016-05-13 |
| IL199674A0 (en) | 2010-04-15 |
| CA2674296A1 (en) | 2008-07-17 |
| JP2010514834A (ja) | 2010-05-06 |
| AU2008204344B2 (en) | 2013-01-31 |
| US8450281B2 (en) | 2013-05-28 |
| WO2008084368A9 (en) | 2009-02-26 |
| RU2009129212A (ru) | 2011-02-10 |
| CA2674296C (en) | 2015-11-24 |
| AU2008204344A1 (en) | 2008-07-17 |
| CN105056207A (zh) | 2015-11-18 |
| IL199674A (en) | 2016-10-31 |
| WO2008084368A2 (en) | 2008-07-17 |
| MX2009007045A (es) | 2009-10-07 |
| EP2124992A2 (en) | 2009-12-02 |
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