CN101616683A - 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 - Google Patents

用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 Download PDF

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Publication number
CN101616683A
CN101616683A CN200880001665A CN200880001665A CN101616683A CN 101616683 A CN101616683 A CN 101616683A CN 200880001665 A CN200880001665 A CN 200880001665A CN 200880001665 A CN200880001665 A CN 200880001665A CN 101616683 A CN101616683 A CN 101616683A
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CN
China
Prior art keywords
cyclosporine
meala
derivative
etval
csa
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Pending
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CN200880001665A
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English (en)
Chinese (zh)
Inventor
保罗·伯纳迪
格里哥尔·弗格尼奥克斯
拉斐尔·克莱博
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Debiopharm SA
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Debiopharm SA
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Publication date
Application filed by Debiopharm SA filed Critical Debiopharm SA
Priority to CN201510378165.7A priority Critical patent/CN105056207A/zh
Publication of CN101616683A publication Critical patent/CN101616683A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN200880001665A 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素 Pending CN101616683A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510378165.7A CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87841407P 2007-01-04 2007-01-04
US60/878,414 2007-01-04

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510378165.7A Division CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Publications (1)

Publication Number Publication Date
CN101616683A true CN101616683A (zh) 2009-12-30

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ID=39514754

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200880001665A Pending CN101616683A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素
CN201510378165.7A Pending CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Family Applications After (1)

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CN201510378165.7A Pending CN105056207A (zh) 2007-01-04 2008-01-03 用于治疗Ullrich先天性肌营养不良的非免疫抑制性环孢霉素

Country Status (12)

Country Link
US (1) US8450281B2 (cg-RX-API-DMAC7.html)
EP (1) EP2124992A2 (cg-RX-API-DMAC7.html)
JP (1) JP5801534B2 (cg-RX-API-DMAC7.html)
CN (2) CN101616683A (cg-RX-API-DMAC7.html)
AU (1) AU2008204344B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0806265A2 (cg-RX-API-DMAC7.html)
CA (1) CA2674296C (cg-RX-API-DMAC7.html)
HK (1) HK1210951A1 (cg-RX-API-DMAC7.html)
IL (1) IL199674A (cg-RX-API-DMAC7.html)
MX (1) MX2009007045A (cg-RX-API-DMAC7.html)
RU (1) RU2462262C2 (cg-RX-API-DMAC7.html)
WO (1) WO2008084368A2 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy
WO2011098809A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
WO2011098805A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
WO2011098808A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
KR101900974B1 (ko) 2010-12-20 2018-09-21 뉴로바이브 파마슈티컬 에이비 상글리페린 유도체 및 이의 제조 방법
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
WO2013169616A1 (en) 2012-05-07 2013-11-14 Novartis Ag Pharmacokinetic modulation with alisporivir
AR090964A1 (es) 2012-05-09 2014-12-17 Novartis Ag Proceso para la elaboracion de undecapeptidos ciclicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE95193T1 (de) * 1987-06-17 1993-10-15 Sandoz Ag Cyclosporine und deren benutzung als arzneimittel.
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US6268398B1 (en) * 1998-04-24 2001-07-31 Mitokor Compounds and methods for treating mitochondria-associated diseases
PT1091975E (pt) * 1998-07-01 2006-05-31 Debiopharm Sa Nova ciclosporina com um perfil de actividade melhorado
US6323039B1 (en) * 1999-06-22 2001-11-27 Mitokor Compositions and methods for assaying subcellular conditions and processes using energy transfer
US7368423B1 (en) 2001-12-05 2008-05-06 The Scripps Research Institute Composition and method for treating chronic allograft rejection
GB0320638D0 (en) * 2003-09-03 2003-10-01 Novartis Ag Organic compounds
WO2009098533A1 (en) * 2008-02-08 2009-08-13 Debiopharm Sa Non -immunosuppressive cyclosporin for the treatment of muscular dystrophy

Also Published As

Publication number Publication date
AU2008204344A9 (en) 2012-06-28
EP2124992A2 (en) 2009-12-02
JP5801534B2 (ja) 2015-10-28
MX2009007045A (es) 2009-10-07
RU2009129212A (ru) 2011-02-10
HK1210951A1 (en) 2016-05-13
IL199674A0 (en) 2010-04-15
IL199674A (en) 2016-10-31
CN105056207A (zh) 2015-11-18
JP2010514834A (ja) 2010-05-06
WO2008084368A8 (en) 2009-09-17
CA2674296C (en) 2015-11-24
WO2008084368A9 (en) 2009-02-26
US20100041593A1 (en) 2010-02-18
CA2674296A1 (en) 2008-07-17
AU2008204344B2 (en) 2013-01-31
AU2008204344A1 (en) 2008-07-17
WO2008084368A2 (en) 2008-07-17
RU2462262C2 (ru) 2012-09-27
BRPI0806265A2 (pt) 2011-09-06
US8450281B2 (en) 2013-05-28

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